Summary of Fuji Astaxanthin Eye Studies 1.18.08
Static Visual Pattern High
Date of Eye fatigue Accommodation Reaction Acuity Depth Acuity (SVA) Critical Flicker evoked frequency Retinal Ocular
First Author/Company Title blood plasma
Publication questionnaire Amplitude accommodation Perception Kinetic Visual Fusion (CFF) potential component Blood flow Pressure
Acuity (KVA) (PVEP) (HFC)
-ve accommodation Test Performed
Effects of Astaxanthin on Eyestrain Induced tendencies with
improved after visual Significant Result Red Text
Iwasaki & Tawara 2006 load (p<0.0429). Also Not significant/inconclusive Black Text
by Accommodative Dysfunction astaxanthin. None
significant after 10 min
change for control. -ve negative
tended to improve.
Improved before and
The supplementation effect of astaxanthin after treatment (p<0.05). Not signficant but
Nagaki et al. 2006 "Stiffness of neck" &
on accommodation and asthenopia. "dimness of sight"
Compared to control acuity tended to
(p<0.01). Magnitude of improve with
improvement is also astaxanthin.
Nagaki et al. 2005
The effect of astaxanthin on retinal capillary
blood flow in normal volunteers.
treated plama levels
astaxanthin. improved significantly
Inconclusive. (p<0.01) (p<0.001).
Nitta et al. 2005
Effect of astaxanthin on accommodation and
asthenopia - Dose Finding - identification
Improved at 12 mg/day
+ve and -ve Not significant but
Inconclusive accommodation rate near acuity
study in healthy volunteers. (p<0.05). Improved
improved (p<0.05) at 6 tended to improve
tendency at 6 mg/day.
mg/dy. with astaxanthin.
Effect of astaxanthin on accommodation and +ve & -ve
Shiratori et al. 2005 asthenopia - Efficacy - identification study in Some improvement Improved at 2 and 4 accommodation speed
healthy volunteers. tendencies. weeks of treatment improved compared to
mitigate decline of
Inconclusive. (p<0.01). start (p<0.01) and
Effects of Astaxanthin on accommodative
Takahashi & Kajita 2005 Not significant. Some Not significant but not significant.
recovery. tendencies. tendency to improve Tendency to
Inconclusive. with astaxanthin. mitigate decline of
before and after
Nakamura et al. 2004
Changes in visual function following peroral
improved at 4 and
No change significant (p<0.05) at 4 No change
and 12 mg/day.
Effects of Astaxanthin on accommodation,
Nagaki et al. 2002
critical flicker fusion, and pattern visual
evoked potential in visual display terminal
Treated group improved
of eye fatigue No change No change
Benefits from taking natural astaxanthin Treated group
Sawaki et al. 2002 characterized by visual acuity and muscle improved
fatigue improvements in humans. No change significantly
compared to start.