BioTech

BioTech Industry 30Nov05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider Insider Net to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Shrs Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Purchased Yield (%) Quarterly Quarterly

Biotechnology & Drugs APPA A.P. Pharma, Inc. NASD Healthcare 39.413 NA NA 1.56 4.52 NA 25.264 24.200 33.76 -0.736 4.21 0.010 NA NA 3.92

Biotechnology & Drugs AAIIQ aaiPharma Inc. OTC Healthcare 6.003 NA NA 0.21 NA NA 28.586 23.000 2.16 -0.764 19.54 0.000 NA NA 0.15

Biotechnology & Drugs ASTM Aastrom Biosciences, Inc. NASD Healthcare 216.289 NA NA 2.10 7.19 NA 102.995 95.900 13.61 1.739 6.89 0.001 NA NA 23.09

Biotechnology & Drugs ABAX Abaxis, Inc. NASD Healthcare 330.953 1.26 27.50 16.53 5.04 65.71 20.021 19.400 49.68 0.205 3.10 -0.014 NA 0.01 5.60

Biotechnology & Drugs ABGX Abgenix, Inc. NASD Healthcare 1,276.837 NA 20.00 14.10 18.70 NA 90.556 80.100 83.84 -2.485 11.55 0.000 NA 381.40 10.61

Biotechnology & Drugs ABRXQ Able Laboratories Inc. OTC Healthcare 1.574 NA NA 0.09 0.01 0.09 18.517 17.700 2.03 -5.998 4.41 0.000 NA 0.00 6.81

Biotechnology & Drugs ACAD ACADIA Pharmaceuticals Inc. NASD Healthcare 241.695 NA NA 10.29 4.91 NA 23.488 17.400 33.80 0.132 25.92 -0.040 NA 3.77 3.45

Biotechnology & Drugs ACAM Acambis plc (ADR) NASD Healthcare 388.691 NA 0.00 7.25 2.23 NA 53.610 46.100 2.61 -0.048 14.01 0.000 NA 6.55 3.00

Biotechnology & Drugs ACCL Accelrys, Inc. NASD Healthcare 214.532 NA NA 8.01 2.43 NA 26.783 26.300 54.31 0.357 1.80 0.000 NA NA 1.57

Biotechnology & Drugs ABPI Accentia Biopharmaceuticals, Inc NASD Healthcare 191.980 NA NA 6.65 NA NA 28.869 2.400 NA NA 91.69 NA NA NA 0.28

Biotechnology & Drugs AKC Access Pharmaceuticals AMEX Healthcare 10.691 NA NA 0.68 NA NA 15.723 14.000 19.53 -0.290 10.96 0.000 NA NA 0.19

Biotechnology & Drugs AGNM Acrongenomics Inc. OTC Healthcare 82.209 NA NA 4.87 9.46 NA 16.881 12.700 0.00 0.000 24.77 0.000 NA 0.13 8.60

Biotechnology & Drugs ACUR Acura Pharmaceuticals, Inc. OTC Healthcare 259.881 NA NA 0.79 NA NA 328.963 291.300 0.72 0.000 11.45 0.000 NA NA 0.37

Biotechnology & Drugs ACUS Acusphere, Inc. NASD Healthcare 106.726 NA NA 4.90 1.55 NA 21.781 19.900 62.60 4.560 8.64 -2.030 NA 34.61 3.23

Biotechnology & Drugs ADZA Adeza Biomedical Corporation NASD Healthcare 325.740 1.07 29.25 18.99 3.65 45.78 17.153 11.300 68.94 1.780 34.12 -0.487 NA NA 13.73

Biotechnology & Drugs ADH Adherex Technologies Inc. (USA) AMEX Healthcare 40.071 NA NA 0.94 1.49 NA 42.629 35.500 10.00 4.262 16.72 0.000 NA NA 8.07

Biotechnology & Drugs ADLR Adolor Corporation NASD Healthcare 548.791 NA 25.00 14.04 6.67 NA 39.088 37.700 81.22 1.660 3.55 0.000 NA NA 6.76

Biotechnology & Drugs ADLS Advanced Life Sciences Holdings, Inc. NASD Healthcare 67.280 NA NA 3.74 6.35 NA 17.989 17.989 32.15 5.783 0.00 0.000 NA 0.29 8.12

Biotechnology & Drugs AVM Advanced Magnetics, Inc. AMEX Healthcare 103.772 NA NA 10.52 NA NA 9.864 8.600 26.40 -0.084 12.81 -0.198 NA NA NA

Biotechnology & Drugs APPI Advanced Plant Pharmaceuticals Inc. OTC Healthcare 1.415 NA NA 0.00 NA NA 786.382 747.100 0.00 -0.020 4.99 0.000 NA NA 0.03

Biotechnology & Drugs ATISZ Advanced Tissue Sciences OTC Healthcare 4.024 NA NA 0.06 0.28 NA 73.155 47.600 1.53 0.004 34.93 0.000 NA 30.74 1.21

Biotechnology & Drugs ADVR Advanced Viral Research OTC Healthcare 56.424 NA NA 0.08 8.10 NA 696.588 647.800 0.05 0.010 7.00 0.000 NA NA 23.84

Biotechnology & Drugs AVNC Advancis Pharmaceutical Corporation NASD Healthcare 38.345 NA 30.00 1.29 0.96 NA 29.725 15.300 8.26 -1.364 48.53 0.000 NA 2.22 3.43

Biotechnology & Drugs ANX ADVENTRX Pharmaceuticals, Inc. AMEX Healthcare 191.356 NA NA 2.85 7.70 NA 67.142 54.700 19.09 8.944 18.53 -0.044 NA NA 15.45

Biotechnology & Drugs AOLS Aeolus Pharmaceuticals, Inc. OTC Healthcare 14.438 NA NA 1.03 23.95 NA 14.017 5.600 5.72 0.000 60.05 0.155 NA 139.15 2.12

Biotechnology & Drugs AEZS AEterna Zentaris Inc. (USA) NASD Healthcare 206.461 NA NA 4.45 1.90 26.27 46.140 42.400 12.87 -0.029 8.11 0.000 NA 42.96 1.64

Biotechnology & Drugs AEMD Aethlon Medical, Inc. OTC Healthcare 5.854 NA NA 0.31 NA NA 18.885 16.500 NA NA 12.63 NA NA NA 0.01

Biotechnology & Drugs AFFX Affymetrix, Inc. NASD Healthcare 3,127.969 1.82 25.17 47.13 9.26 53.03 66.369 66.100 85.82 -8.899 0.41 -0.281 NA 35.52 4.45

Biotechnology & Drugs AKES Akesis Pharmaceuticals Inc OTC Healthcare 37.481 NA NA 2.50 83.33 NA 14.993 6.100 NA NA 59.31 NA NA NA 5.09

Biotechnology & Drugs AKN Akorn, Inc. AMEX Healthcare 109.302 NA NA 4.07 22.49 NA 26.856 10.800 23.57 -0.176 59.79 0.000 NA 17.27 2.30

Biotechnology & Drugs AMRI Albany Molecular Research NASD Healthcare 407.721 2.31 15.00 12.60 1.30 19.55 32.359 27.500 65.64 2.447 15.02 0.000 NA 7.67 7.28

Biotechnology & Drugs ALXN Alexion Pharmaceuticals, Inc. NASD Healthcare 606.489 NA NA 19.65 8.18 NA 30.865 30.300 94.86 2.286 1.83 -0.035 NA 221.99 8.14

Biotechnology & Drugs ACEL Alfacell Corporation NASD Healthcare 46.549 NA NA 1.27 14.43 NA 36.653 36.000 14.71 0.027 1.78 0.000 NA 0.00 2.77

Biotechnology & Drugs AGRX AlgoRx Pharmaceuticals, Inc. NASD Healthcare NA NA NA NA NA NA NA NA NA NA 100.00 NA NA NA NA

Biotechnology & Drugs ALKS Alkermes, Inc. NASD Healthcare 1,684.314 13.01 7.80 18.60 NA NA 90.555 87.600 95.00 5.680 3.26 -0.015 NA NA 3.78

Biotechnology & Drugs AGN Allergan, Inc. NYSE Healthcare 13,110.862 1.55 17.15 99.62 9.79 35.35 131.609 129.000 95.00 -0.732 1.98 0.000 0.40 52.37 2.71

Biotechnology & Drugs ALLP Alliance Pharmaceutical Corp. OTC Healthcare 3.309 NA NA 0.10 NA NA 34.830 32.000 0.92 -0.007 8.13 0.000 NA NA 0.50

Biotechnology & Drugs ALTH Allos Therapeutics, Inc. NASD Healthcare 115.629 NA NA 2.10 1.98 NA 55.061 32.800 23.13 0.542 40.43 0.002 NA NA 16.73

Biotechnology & Drugs ALNY Alnylam Pharmaceuticals, Inc. NASD Healthcare 341.681 NA NA 12.83 11.79 NA 26.631 10.100 16.42 2.445 62.07 0.000 NA 32.71 3.34

Biotechnology & Drugs APNO Alpha Innotech Corp. OTC Healthcare 1.901 NA NA 1.15 0.93 NA 1.653 1.420 NA NA 14.10 NA NA NA 19.31

Biotechnology & Drugs ALO Alpharma Inc. NYSE Healthcare NA NA 21.52 NA 1.66 NA 53.487 40.900 75.94 -2.883 23.53 -0.025 NA 58.73 1.06

Biotechnology & Drugs AAA Altana AG(ADR) NYSE Healthcare 7,103.537 NA 20.50 52.60 3.14 14.37 135.285 67.600 2.62 -2.256 50.03 0.000 2.31 3.00 NA

Biotechnology & Drugs ALT Alteon Inc. AMEX Healthcare 12.179 NA NA 0.21 1.59 NA 57.997 53.400 11.19 -2.582 7.93 0.000 NA NA 6.76

Biotechnology & Drugs ALTU Altus Pharmaceuticals Inc. NASD Healthcare NA NA NA NA NA NA NA NA NA NA NA NA NA NA NA

Biotechnology & Drugs AMAR Amarillo Biosciences, Inc OTC Healthcare 8.475 NA NA 0.52 NA NA 16.298 12.100 0.10 0.013 25.76 -0.012 NA NA 0.01

Biotechnology & Drugs AMRN Amarin Corporation plc (ADR) NASD Healthcare 0.000 NA NA 1.16 NA NA 0.000 0.000 0.10 0.002 0.00 0.000 NA NA 2.92

Biotechnology & Drugs MABAA American Biogenetic Sciences, Inc. OTC Healthcare 0.004 NA NA 0.00 NA NA 44.950 34.500 NA NA 23.25 NA NA NA 0.06

Biotechnology & Drugs AOB American Oriental Bioengineering, Inc. AMEX Healthcare 216.757 NA NA 4.35 4.08 14.86 49.829 16.900 4.50 2.244 66.08 0.000 NA 7.28 3.62

Biotechnology & Drugs APPX American Pharmaceutical Partners, Inc. NASD Healthcare 2,610.006 0.69 27.48 36.03 6.48 31.33 72.440 20.800 33.65 4.656 71.29 0.000 NA NA 5.37

Biotechnology & Drugs ABC AmerisourceBergen Corp. NYSE Healthcare 8,242.502 1.32 13.05 79.41 1.96 29.50 103.797 102.700 95.00 1.339 1.06 -0.125 0.25 22.26 1.32

Biotechnology & Drugs AMGN Amgen, Inc. NASD Healthcare 100,769.875 1.33 16.53 81.64 4.91 29.27 1,234.320 1,226.000 72.41 32.576 0.67 -2.087 NA 19.25 1.80

Biotechnology & Drugs AMLN Amylin Pharmaceuticals NASD Healthcare 4,142.978 NA NA 37.61 31.95 NA 110.156 104.600 95.00 15.505 5.04 -0.209 NA 289.40 8.42

Biotechnology & Drugs ANDS Anadys Pharmaceuticals, Inc. NASD Healthcare 265.711 NA NA 9.38 3.27 NA 28.327 24.400 55.38 7.089 13.86 -0.542 NA 34.49 8.37

Biotechnology & Drugs ADRX Andrx Corporation NASD Healthcare 1,321.200 1.05 17.64 18.00 1.72 17.65 73.400 71.700 79.52 -1.994 2.32 0.000 NA NA 2.99

Biotechnology & Drugs ANPI Angiotech Pharmaceuticals, Inc. (USA) NASD Healthcare 1,252.698 0.82 20.00 14.89 2.48 13.97 84.130 83.300 54.29 4.220 0.99 0.000 NA NA 8.62

Biotechnology & Drugs ANIK Anika Therapeutics, Inc. NASD Healthcare 127.895 0.59 30.00 12.18 3.45 20.39 10.500 9.700 44.04 -0.306 7.62 -0.033 NA NA 8.49

Biotechnology & Drugs ANXB Antex Biologics, Inc. OTC Healthcare 0.127 NA NA 0.01 NA NA 12.408 10.300 NA NA 16.99 NA NA NA 0.79

Biotechnology & Drugs AGEN Antigenics, Inc. NASD Healthcare 255.767 NA 0.00 5.61 5.14 NA 45.591 24.300 17.77 0.056 46.70 0.000 NA 111.71 4.52

Biotechnology & Drugs APHT Aphton Corporation NASD Healthcare 24.223 NA NA 0.40 NA NA 60.556 58.800 30.72 0.647 2.90 0.000 NA NA 0.88

Biotechnology & Drugs ARNA Arena Pharmaceuticals, Inc. NASD Healthcare 383.958 NA 30.00 10.85 3.24 NA 35.388 32.500 87.54 4.113 8.16 0.011 NA NA 2.46

Biotechnology & Drugs AGNT Argonaut Technologies, Inc OTC Healthcare 5.422 NA NA 0.26 0.17 NA 20.774 20.300 4.12 -5.132 2.28 -5.157 NA 0.21 5.64

Biotechnology & Drugs ARIA Ariad Pharmaceuticals, Inc. NASD Healthcare 393.868 NA NA 6.39 4.60 NA 61.638 57.000 52.30 6.713 7.53 0.000 NA 9.51 6.13

Biotechnology & Drugs ARQL ArQule, Inc. NASD Healthcare 254.078 NA NA 7.20 2.35 NA 35.289 34.500 57.00 1.621 2.24 0.001 NA 0.51 6.86

Biotechnology & Drugs ARRY Array BioPharma Inc. NASD Healthcare 259.098 NA 37.50 6.71 2.82 NA 38.614 34.800 72.97 0.429 9.88 -0.005 NA 12.35 6.64

Biotechnology & Drugs ARWR Arrowhead Research Corporation NASD Healthcare 107.739 NA NA 3.85 3.79 NA 27.984 13.700 10.81 1.122 51.04 0.000 NA NA 25.85







492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 30Nov05 1 of 45 10/24/2011 3:30 PM

BioTech Industry 30Nov05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider Insider Net to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Shrs Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Purchased Yield (%) Quarterly Quarterly

Biotechnology & Drugs ASPV Aspreva Pharmaceuticals Corporation NASD Healthcare 443.921 1.01 16.00 13.00 3.81 NA 34.148 19.100 28.45 1.656 44.07 0.000 NA 1.05 8.15

Biotechnology & Drugs ASTR Astralis, Ltd. OTC Healthcare 5.487 NA NA 0.06 NA NA 91.455 24.000 0.00 0.000 73.76 -0.005 NA NA 0.61

Biotechnology & Drugs AGIX AtheroGenics, Inc. NASD Healthcare 576.796 NA 25.00 15.19 NA NA 37.972 36.500 95.00 0.317 3.88 0.450 NA NA 19.19

Biotechnology & Drugs AIMM AutoImmune Inc. OTC Healthcare 15.566 NA NA 0.92 1.66 NA 16.920 16.800 28.37 0.012 0.71 0.000 NA NA 96.54

Biotechnology & Drugs AUXL Auxilium Pharmaceuticals, Inc. NASD Healthcare 162.242 NA 30.00 5.56 3.73 NA 29.180 20.800 79.34 4.569 28.72 3.503 NA 15.56 3.77

Biotechnology & Drugs AVN AVANIR Pharmaceuticals AMEX Healthcare 323.993 NA NA 2.99 31.15 NA 108.359 98.400 36.52 0.893 9.19 0.566 NA 9.48 2.36

Biotechnology & Drugs AVAN AVANT Immunotherapeutics, Inc. NASD Healthcare 129.782 NA NA 1.75 5.26 NA 74.161 73.700 20.07 0.150 0.62 0.000 NA 8.09 7.97

Biotechnology & Drugs AVXT AVAX Technologies, Inc. OTC Healthcare 19.389 NA NA 0.31 2.56 NA 62.546 61.300 3.63 0.000 1.99 0.000 NA 4.47 3.38

Biotechnology & Drugs AVII AVI BioPharma, Inc. NASD Healthcare 157.296 NA NA 3.56 4.25 NA 44.184 37.700 8.72 0.768 14.68 0.012 NA NA 12.48

Biotechnology & Drugs AVGN Avigen, Inc. NASD Healthcare 62.722 NA NA 3.00 1.08 NA 20.907 20.900 41.28 -0.127 0.03 0.000 NA 13.72 42.11

Biotechnology & Drugs AXCA Axcan Pharma Inc. (USA) NASD Healthcare 686.603 1.37 15.00 15.03 1.64 27.32 45.682 42.000 56.73 3.535 8.06 0.000 NA 30.61 3.26

Biotechnology & Drugs AXJ AXM Pharma, Inc. AMEX Healthcare 8.217 NA NA 0.42 0.95 NA 19.564 11.400 2.31 -0.147 41.73 0.000 NA 41.96 0.99

Biotechnology & Drugs AXYX Axonyx Inc. NASD Healthcare 48.307 NA NA 0.90 0.77 NA 53.681 51.900 22.29 0.305 3.32 0.000 NA 0.00 9.59

Biotechnology & Drugs BRL Barr Pharmaceuticals, Inc. NYSE Healthcare 6,188.806 1.07 15.87 57.52 4.41 24.76 107.594 99.300 75.10 1.328 7.71 -1.002 NA 1.51 4.82

Biotechnology & Drugs BTRX Barrier Therapeutics, Inc. NASD Healthcare 174.681 NA 15.00 7.25 2.02 14.72 24.094 14.900 57.45 -0.558 38.16 0.000 NA 0.59 10.50

Biotechnology & Drugs BGCC Beluga Composites Corp. OTC Healthcare 0.021 NA NA 0.60 NA NA 0.035 0.008 NA NA 77.14 NA NA 2.06 2.46

Biotechnology & Drugs BNT Bentley Pharmaceuticals, Inc. NYSE Healthcare 392.930 0.87 37.00 17.99 4.41 43.98 21.842 19.500 42.36 0.884 10.72 0.009 NA 2.78 2.53

Biotechnology & Drugs BASI Bioanalytical Systems, Inc. NASD Healthcare 25.521 NA NA 5.24 1.30 NA 4.871 3.200 13.92 -0.014 34.31 0.000 NA 78.08 1.49

Biotechnology & Drugs BCRX BioCryst Pharmaceuticals, Inc. NASD Healthcare 392.256 NA NA 14.83 11.36 NA 26.450 20.700 40.65 1.198 21.74 -0.095 NA NA 9.13

Biotechnology & Drugs BDSI BioDelivery Sciences International, Inc. NASD Healthcare 32.294 NA NA 2.75 NA NA 11.743 3.700 2.50 0.215 68.49 0.339 NA 161.51 0.16

Biotechnology & Drugs BIVN Bioenvision, Inc. NASD Healthcare 236.005 12.66 10.00 5.79 3.80 NA 40.761 38.300 46.38 1.939 6.04 -0.080 NA NA 8.35

Biotechnology & Drugs BIIB Biogen Idec Inc NASD Healthcare 14,737.176 1.51 14.07 43.42 2.15 111.59 339.410 338.200 79.06 18.510 0.36 -0.131 NA 0.63 2.75

Biotechnology & Drugs BMRN BioMarin Pharmaceutical NASD Healthcare 766.965 NA NA 10.38 NA NA 73.889 72.000 79.52 9.941 2.56 -0.032 NA NA 1.86

Biotechnology & Drugs BIOM Biomira Inc. (USA) NASD Healthcare 121.259 NA NA 1.53 5.85 NA 78.817 78.000 2.78 0.280 1.04 0.000 NA 0.56 9.25

Biotechnology & Drugs BNTK Bionet Technologies, Inc. OTC Healthcare 0.001 NA NA 0.00 0.01 NA 13.813 8.700 NA NA 37.02 NA NA NA 0.90

Biotechnology & Drugs BNRX Bionutrics, Inc. OTC Healthcare 70.065 NA NA 3.10 5.94 NA 22.602 6.400 NA NA 71.68 NA NA 11.45 0.07

Biotechnology & Drugs BPRG BioProgress PLC (USA) NASD Healthcare 87.804 NA NA 7.76 1.87 NA 11.314 10.750 0.20 0.001 4.99 0.000 NA NA 2.83

Biotechnology & Drugs BIOP BioPulse International OTC Healthcare 0.020 NA NA 0.00 NA NA 15.452 7.600 NA NA 50.81 NA NA NA 0.04

Biotechnology & Drugs BPUR Biopure Corporation NASD Healthcare 23.872 NA NA 0.98 0.53 NA 24.359 23.100 2.55 0.152 5.17 0.010 NA NA 4.43

Biotechnology & Drugs BPA BioSante Pharmaceuticals, Inc. AMEX Healthcare 83.804 NA NA 4.32 9.13 NA 19.399 16.900 23.87 -0.290 12.88 0.000 NA NA 7.03

Biotechnology & Drugs BSTE Biosite Incorporated NASD Healthcare 1,009.542 1.20 15.83 57.95 3.43 20.15 17.421 15.900 93.03 0.111 8.73 -0.023 NA 6.33 4.37

Biotechnology & Drugs BSTC BioSpecifics Technologies Corp. OTC Healthcare 7.990 NA NA 1.50 4.14 NA 5.326 3.000 2.68 0.000 43.67 0.000 NA 103.33 0.65

Biotechnology & Drugs BIOHF Biotech Holdings Ltd. (USA) OTC Healthcare 15.766 NA NA 0.17 NA NA 92.230 45.200 0.00 0.000 50.99 0.000 NA NA 0.47

Biotechnology & Drugs BTIM BioTime, Inc. OTC Healthcare 5.361 NA NA 0.30 NA NA 17.871 17.200 1.91 0.036 3.76 0.060 NA NA 2.63

Biotechnology & Drugs BTRNQ BioTransplant Inc. OTC Healthcare 0.381 NA NA 0.02 0.03 NA 25.386 19.600 0.00 0.000 22.79 0.000 NA 3.76 2.39

Biotechnology & Drugs BVF Biovail Corporation (USA) NYSE Healthcare 3,862.305 0.77 14.62 24.22 3.27 22.42 159.468 124.400 43.61 17.378 21.99 0.000 8.26 37.88 2.70

Biotechnology & Drugs BLSI Boston Life Sciences, Inc. NASD Healthcare 21.470 NA NA 2.06 11.64 NA 10.422 8.600 4.41 -0.036 17.48 0.000 NA NA 1.65

Biotechnology & Drugs BDY Bradley Pharmaceuticals, Inc. NYSE Healthcare 196.379 0.52 15.00 12.40 1.22 10.18 15.837 13.900 62.37 0.061 12.23 0.000 NA 66.55 3.27

Biotechnology & Drugs KDUS Cadus Corporation OTC Healthcare 21.030 NA NA 1.60 0.83 NA 13.144 7.500 7.59 0.027 42.94 0.000 NA NA 508.23

Biotechnology & Drugs KAL Callisto Pharmaceuticals, Inc. AMEX Healthcare 41.548 NA NA 1.33 14.78 NA 31.239 25.500 7.10 0.033 18.37 0.010 NA NA 2.61

Biotechnology & Drugs CBM Cambrex Corporation NYSE Healthcare 491.084 NA NA 18.41 1.33 30.37 26.675 25.700 95.00 2.941 3.65 -0.254 0.65 50.49 2.62

Biotechnology & Drugs CATG Cambridge Antibody Tech. Group plc (ADR) NASD Healthcare 606.710 NA 0.00 11.75 2.51 NA 51.620 32.100 3.26 -0.271 37.81 0.000 NA NA 4.38

Biotechnology & Drugs CNVX CancerVax Corporation NASD Healthcare 37.917 NA NA 1.36 0.78 NA 27.880 17.300 22.02 -0.201 37.95 0.000 NA 37.14 5.41

Biotechnology & Drugs CPD A

Caraco Pharmaceutical Laboratories Ltd. MEX Healthcare 242.847 0.18 44.00 9.20 NA NA 26.396 9.500 12.60 0.116 64.01 0.000 NA NA 3.09

Biotechnology & Drugs CAH Cardinal Health, Inc. NYSE Healthcare 27,470.902 1.28 13.00 64.15 3.09 26.25 428.229 422.600 85.74 16.170 1.31 -0.336 0.37 29.39 1.33

Biotechnology & Drugs CRME Cardiome Pharma Corp.(USA) NASD Healthcare 437.311 NA NA 8.55 6.94 NA 50.865 49.800 43.29 4.302 2.09 0.000 NA 1.07 7.98

Biotechnology & Drugs CVBT Cardiovascular Biotherapeutics, Inc. OTC Healthcare 637.405 NA NA 5.18 56.92 NA 123.051 22.100 0.00 0.000 82.04 -0.033 NA 0.00 109.31

Biotechnology & Drugs CARN Carrington Laboratories, Inc. NASD Healthcare 45.518 NA NA 4.22 3.80 NA 10.786 9.500 8.27 -0.040 11.92 0.000 NA 34.05 1.07

Biotechnology & Drugs CRA Celera Genomics, Applera Corp NYSE Healthcare 929.415 NA 0.00 12.48 NA NA 74.472 73.400 79.72 1.400 1.44 0.000 NA NA NA

Biotechnology & Drugs CELG Celgene Corporation NASD Healthcare 10,346.150 1.37 47.45 61.00 17.73 175.19 169.609 165.600 77.70 -3.154 2.36 0.000 NA 68.58 6.34

Biotechnology & Drugs CEGE Cell Genesys, Inc. NASD Healthcare 262.347 NA NA 5.76 2.91 NA 45.546 45.200 63.24 0.036 0.76 0.013 NA 217.36 2.42

Biotechnology & Drugs CTIC Cell Therapeutics, Inc. NASD Healthcare 164.538 NA 0.00 2.29 NA NA 71.851 68.800 16.76 -2.047 4.25 -0.062 NA NA 0.91

Biotechnology & Drugs CLGY Cellegy Pharmaceuticals, Inc. NASD Healthcare 18.197 NA NA 0.61 NA NA 29.832 23.900 13.79 0.240 19.89 -0.005 NA NA 1.84

Biotechnology & Drugs CVM CEL-SCI Corporation AMEX Healthcare 36.369 NA NA 0.49 15.31 NA 74.222 6.730 1.26 -0.105 90.93 -0.359 NA 0.00 7.39

Biotechnology & Drugs CEPH Cephalon, Inc. NASD Healthcare 2,967.175 0.88 19.43 51.08 5.02 NA 58.089 57.600 NA NA 0.84 -0.021 NA 288.78 4.75

Biotechnology & Drugs CERS Cerus Corporation NASD Healthcare 199.991 NA NA 8.92 5.16 18.61 22.420 21.600 42.64 1.817 3.66 0.000 NA 12.22 4.10

Biotechnology & Drugs CHTL Chantal Pharmaceutical OTC Healthcare 0.004 NA NA 0.00 0.00 NA 40.810 31.400 NA NA 23.06 NA NA 62.29 0.26

Biotechnology & Drugs CHTT Chattem Inc. NASD Healthcare 659.519 1.08 13.00 33.58 5.25 34.46 19.640 18.200 78.21 1.962 7.33 -0.284 NA 143.26 3.82

Biotechnology & Drugs CXSP ChemGenex Pharmaceuticals Limited (ADR) NASD Healthcare 87.841 NA NA 7.60 NA NA 11.480 6.770 0.03 0.003 41.03 0.000 NA NA NA

Biotechnology & Drugs CHIR Chiron Corporation NASD Healthcare 8,355.791 1.40 17.60 44.31 3.31 452.14 188.576 108.900 47.11 -0.333 42.25 0.000 NA 43.51 3.14

Biotechnology & Drugs CLRI Clearant Inc. OTC Healthcare 108.500 NA NA 2.73 52.50 NA 39.744 26.800 NA NA 32.57 NA NA 5.15 0.96

Biotechnology & Drugs CNXS CNS, Inc. NASD Healthcare 343.263 1.16 15.33 24.10 4.74 20.98 14.243 12.400 64.31 0.605 12.94 -0.252 1.00 NA 5.07

Biotechnology & Drugs CLSCE Cobalis Corporation OTC Healthcare 41.530 NA NA 1.64 NA NA 25.323 9.100 0.00 0.000 64.06 -2.298 NA NA 0.08

Biotechnology & Drugs COLY Coley Pharmaceutical Group, Inc. NASD Healthcare 402.759 NA NA 16.24 2.46 NA 24.800 24.800 20.14 4.994 0.00 0.000 NA 3.85 18.70

Biotechnology & Drugs CGPI CollaGenex Pharmaceutical, Inc NASD Healthcare 148.653 NA NA 10.26 5.23 NA 14.489 14.300 50.80 -0.246 1.30 0.024 NA NA 3.32





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 30Nov05 2 of 45 10/24/2011 3:30 PM

BioTech Industry 30Nov05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider Insider Net to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Shrs Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Purchased Yield (%) Quarterly Quarterly

Biotechnology & Drugs CBRX Columbia Laboratories NASD Healthcare 159.075 NA NA 3.81 NA NA 41.752 40.800 38.34 -1.155 2.28 -0.020 NA NA 2.69

Biotechnology & Drugs CRXX CombinatoRx, Incorporated NASD Healthcare NA NA NA NA NA NA 22.321 6.000 NA NA 73.12 NA NA 48.10 5.07

Biotechnology & Drugs CBTE Commonwealth Biotechnologies, Inc. NASD Healthcare 16.268 NA NA 5.00 2.68 NA 3.254 3.000 10.02 -0.006 7.81 -0.025 NA 79.88 5.07

Biotechnology & Drugs COGE Compare Generiks, Inc. OTC Healthcare 0.000 NA NA 0.00 0.00 0.00 4.915 3.800 NA NA 22.69 NA NA NA 1.34

Biotechnology & Drugs CGEN Compugen Ltd. (USA) NASD Healthcare 74.860 NA NA 2.70 1.90 NA 27.726 18.300 29.98 0.248 34.00 0.000 NA NA 13.67

Biotechnology & Drugs CNCT Connetics Corporation NASD Healthcare 465.829 0.59 24.43 13.23 3.93 20.53 35.210 34.800 95.00 -2.472 1.16 -0.214 NA 244.75 6.81

Biotechnology & Drugs VEGF Corautus Genetics Inc. NASD Healthcare 83.326 NA NA 4.25 5.35 NA 19.606 15.900 12.29 -0.451 18.90 0.000 NA 101.81 7.76

Biotechnology & Drugs CORT Corcept Therapeutics Incorporated NASD Healthcare 104.439 NA NA 4.60 3.30 NA 22.704 9.100 21.56 -0.100 59.92 -0.076 NA 0.14 11.54

Biotechnology & Drugs CONX Corgenix Medical Corporation OTC Healthcare 3.964 NA NA 0.42 1.28 NA 9.438 7.400 0.00 0.000 21.59 0.064 NA 42.14 3.34

Biotechnology & Drugs CGTK Corgentech, Inc. NASD Healthcare 62.617 NA NA 2.23 0.70 NA 28.079 17.400 40.38 0.705 38.03 0.000 NA 0.51 18.30

Biotechnology & Drugs COR Cortex Pharmaceuticals AMEX Healthcare 77.062 NA NA 2.35 4.10 NA 32.792 32.400 3.55 -0.365 1.20 0.000 NA NA 10.26

Biotechnology & Drugs CTRX Cotherix, Inc NASD Healthcare 367.936 NA 30.00 12.99 5.28 NA 28.325 15.800 26.82 2.277 44.22 -2.098 NA NA 6.59

Biotechnology & Drugs CVGR Covalent Group, Inc. NASD Healthcare 27.124 NA NA 2.01 3.89 NA 13.501 10.600 31.71 1.108 21.49 0.000 NA 1.00 2.46

Biotechnology & Drugs CVD Covance Inc. NYSE Healthcare 3,030.755 1.15 17.83 48.44 4.32 26.48 62.567 62.100 83.73 0.498 0.75 -0.064 NA NA 2.35

Biotechnology & Drugs CRTX Critical Therapeutics, Inc. NASD Healthcare 208.493 NA NA 6.11 2.40 NA 34.123 16.700 22.69 0.336 51.06 4.683 NA 2.34 5.97

Biotechnology & Drugs CRXL Crucell N.V. (ADR) NASD Healthcare 937.153 NA NA 25.46 6.23 NA 36.873 32.400 17.79 0.835 12.13 0.000 NA 0.47 9.39

Biotechnology & Drugs CBST Cubist Pharmaceuticals NASD Healthcare 1,253.475 3.81 28.00 23.33 57.75 NA 53.728 53.700 95.00 0.849 0.05 -0.003 NA 760.16 4.70

Biotechnology & Drugs CRGN CuraGen Corporation NASD Healthcare 233.082 NA NA 4.19 3.25 NA 55.628 47.500 64.66 3.033 14.61 0.015 NA 245.43 10.89

Biotechnology & Drugs CRIS Curis, Inc. NASD Healthcare 190.452 NA NA 3.86 4.49 NA 49.340 48.100 38.46 0.996 2.51 -0.067 NA 12.95 4.63

Biotechnology & Drugs CVTX CV Therapeutics, Inc. NASD Healthcare 1,108.829 NA NA 24.79 8.64 NA 44.729 43.800 95.00 0.378 2.08 -0.056 NA 311.40 9.59

Biotechnology & Drugs CYAN Cyanotech Corporation NASD Healthcare 13.583 NA NA 0.65 0.91 166.24 20.896 16.800 0.26 -2.344 19.60 0.000 NA 12.92 5.11

Biotechnology & Drugs CYCC Cyclacel Group plc. (ADR) NASD Healthcare NA NA NA NA NA NA NA NA NA NA 100.00 NA NA NA NA

Biotechnology & Drugs CYPB Cypress Bioscience, Inc. NASD Healthcare 178.950 NA NA 5.61 1.96 NA 31.898 31.600 73.56 0.336 0.93 -0.090 NA 0.00 22.04

Biotechnology & Drugs CYTO Cytogen Corporation NASD Healthcare 57.162 NA NA 3.05 1.92 NA 18.741 18.700 33.83 0.345 0.22 0.000 NA 0.17 5.02

Biotechnology & Drugs CYTK Cytokinetics, Inc. NASD Healthcare 241.901 NA NA 8.44 3.09 NA 28.661 19.900 45.44 1.253 30.57 -0.085 NA 12.17 7.77

Biotechnology & Drugs GTF Cytomedix, Inc. AMEX Healthcare 56.932 NA NA 2.18 7.90 NA 26.116 25.500 2.91 -0.507 2.36 0.135 NA NA 3.67

Biotechnology & Drugs CYTR CytRx Corporation NASD Healthcare 5.478 NA NA 0.93 5.08 NA 5.891 5.300 7.81 -1.078 10.03 0.000 NA NA 6.52

Biotechnology & Drugs DATA DATATRAK International, Inc. NASD Healthcare 119.236 NA NA 11.57 9.68 78.56 10.306 9.700 42.65 0.225 5.88 -0.025 NA NA 5.71

Biotechnology & Drugs DCGN deCODE genetics, Inc. NASD Healthcare 466.068 NA NA 8.52 43.03 NA 54.703 47.100 39.12 0.219 13.90 -0.005 NA 1,455.58 7.73

Biotechnology & Drugs DGENQ Deltagen, Inc. OTC Healthcare 15.152 NA NA 0.39 1.11 NA 38.852 14.000 15.91 0.000 63.97 0.000 NA 36.70 0.23

Biotechnology & Drugs DNDN Dendreon Corporation NASD Healthcare 345.512 NA NA 5.82 2.40 NA 59.366 58.700 42.42 0.963 1.12 0.000 NA 3.01 7.12

Biotechnology & Drugs DEPO DepoMed, Inc. NASD Healthcare 237.605 2.15 30.00 5.86 NA NA 40.547 29.900 60.02 0.525 26.26 -0.023 NA 0.00 2.09

Biotechnology & Drugs DSCI Derma Sciences, Inc. OTC Healthcare 7.370 NA NA 0.60 0.97 NA 12.284 3.900 0.21 0.000 68.25 0.000 NA 19.37 2.04

Biotechnology & Drugs DIGE Digene Corporation NASD Healthcare 555.211 0.96 30.00 27.57 6.67 NA 20.138 15.500 91.65 2.222 23.03 -1.136 NA 0.79 3.56

Biotechnology & Drugs DSCO Discovery Laboratories NASD Healthcare 370.516 NA NA 6.89 10.45 NA 53.776 46.800 40.09 -0.184 12.97 0.635 NA 29.66 6.48

Biotechnology & Drugs DPII Discovery Partners Int'l NASD Healthcare 60.950 NA NA 2.31 NA NA 26.385 25.600 74.74 1.544 2.97 0.000 NA NA NA

Biotechnology & Drugs DVSA Diversa Corporation NASD Healthcare 235.642 NA 50.00 5.26 1.98 NA 44.799 26.500 41.69 -1.334 40.85 -0.003 NA 11.94 3.29

Biotechnology & Drugs DOCP DocPlanet.com Inc. OTC Healthcare 0.001 NA NA 0.00 NA NA 7.596 4.100 0.03 0.000 46.02 0.000 NA NA 0.38

Biotechnology & Drugs DOR DOR BioPharma, Inc. AMEX Healthcare 12.653 NA NA 0.25 2.72 NA 50.612 48.300 7.25 -0.193 4.57 0.000 NA 2.48 3.33

Biotechnology & Drugs DOVP DOV Pharmaceutical, Inc. NASD Healthcare 329.631 NA NA 14.28 NA NA 23.083 21.300 88.84 0.241 7.72 -0.512 NA NA 6.57

Biotechnology & Drugs RDY Dr Reddy's Laboratories Limited (ADR) NYSE Healthcare 1,621.322 1.57 15.00 21.20 NA 98.87 76.539 56.600 18.79 0.571 26.05 0.000 0.54 NA NA

Biotechnology & Drugs DRUG Dragon Pharmaceuticals Inc. (USA) OTC Healthcare 40.871 NA NA 0.65 1.32 116.28 62.878 19.200 0.00 0.000 69.46 0.000 NA 136.36 0.92

Biotechnology & Drugs DRAX DRAXIS Health Inc. (USA) NASD Healthcare 170.985 NA NA 4.11 2.12 19.17 41.602 34.100 38.60 -0.274 18.03 0.000 NA NA 3.56

Biotechnology & Drugs DRRX DURECT Corporation NASD Healthcare 290.928 NA NA 5.46 26.76 NA 53.283 45.200 53.22 4.454 15.17 -0.327 NA 538.95 6.13

Biotechnology & Drugs DUSA DUSA Pharmaceuticals, Inc NASD Healthcare 180.895 NA NA 10.68 4.57 NA 16.938 15.800 70.81 1.124 6.72 0.000 NA NA 10.87

Biotechnology & Drugs DIL Dyadic International, Inc. AMEX Healthcare 47.583 NA NA 2.11 2.68 NA 22.551 15.300 4.46 -0.159 32.15 -0.008 NA 21.19 6.59

Biotechnology & Drugs DYAX Dyax Corp. NASD Healthcare 161.980 NA NA 4.26 3.48 NA 38.024 35.700 51.72 0.023 6.11 0.000 NA 24.52 3.71

Biotechnology & Drugs DVAX Dynavax Technologies Corporation NASD Healthcare 130.934 NA NA 4.40 2.20 NA 29.758 24.200 31.92 0.867 18.68 -0.025 NA NA 8.75

Biotechnology & Drugs EW Edwards Lifesciences Corp NYSE Healthcare 2,414.228 1.39 13.30 40.60 3.68 38.29 59.464 56.500 95.00 -0.885 4.99 -0.132 NA 38.15 2.10

Biotechnology & Drugs ESALY Eisai Co., Ltd (ADR) OTC Healthcare 11,280.536 1.35 12.70 39.55 2.96 25.03 285.786 211.500 0.37 0.008 26.00 0.000 NA 0.18 2.44

Biotechnology & Drugs ELN Elan Corporation, plc (ADR) NYSE Healthcare 4,394.210 NA 22.60 10.30 53.65 NA 426.622 418.100 27.91 0.855 2.00 0.000 NA 2,460.00 3.99

Biotechnology & Drugs ELI Elite Pharmaceuticals, Inc. AMEX Healthcare 33.746 NA NA 1.86 7.13 NA 18.143 18.000 9.64 -1.105 0.79 0.032 NA 55.75 3.77

Biotechnology & Drugs EMBX Embrex, Inc. NASD Healthcare 119.476 NA NA 14.69 2.30 38.69 8.133 7.200 39.62 -0.053 11.47 -0.032 NA 16.98 2.75

Biotechnology & Drugs EMIS Emisphere Technologies Inc. NASD Healthcare 110.531 NA NA 4.73 NA NA 23.368 23.000 30.61 -1.021 1.58 0.000 NA NA 1.40

Biotechnology & Drugs ENCY Encysive Pharmaceuticals, Inc. NASD Healthcare 646.759 NA 12.50 11.07 78.51 NA 58.424 57.500 95.00 3.251 1.58 -0.124 NA 1,576.90 7.27

Biotechnology & Drugs ENDP Endo Pharmaceuticals NASD Healthcare 4,025.278 0.79 20.48 30.33 5.05 25.46 132.716 69.100 55.43 1.496 47.93 -115.694 NA NA 2.13

Biotechnology & Drugs EVSC Endovasc, Inc. OTC Healthcare 3.289 NA NA 0.03 8.67 NA 126.496 118.200 0.05 0.000 6.56 -0.243 NA 52.25 1.86

Biotechnology & Drugs ENMD EntreMed, Inc. NASD Healthcare 106.154 NA NA 2.12 3.75 NA 50.073 34.600 13.13 0.277 30.90 0.000 NA NA 8.10

Biotechnology & Drugs ETOP Entropin, Inc. OTC Healthcare 0.613 NA NA 0.02 NA NA 30.645 23.300 0.01 0.000 23.97 0.000 NA NA 18.60

Biotechnology & Drugs ENZN Enzon Pharmaceuticals, Inc. NASD Healthcare 312.258 2.05 39.00 7.04 1.55 NA 44.355 44.300 76.12 -0.805 0.12 0.022 NA 198.07 5.99

Biotechnology & Drugs EPCT EpiCept Corporation NASD Healthcare NA NA NA NA NA NA NA NA NA NA 100.00 NA NA NA NA

Biotechnology & Drugs EPIX EPIX Pharmaceuticals, Inc. NASD Healthcare 109.160 NA NA 4.69 4.73 NA 23.275 23.000 59.61 -0.742 1.18 0.000 NA 498.22 5.07

Biotechnology & Drugs ERGO Ergo Science Corporation OTC Healthcare 5.814 NA NA 1.00 0.30 NA 5.814 5.500 1.93 -0.017 5.40 0.000 NA NA 1.16

Biotechnology & Drugs EXAS EXACT Sciences Corporation NASD Healthcare 37.907 NA 50.00 1.44 1.39 NA 26.324 22.400 47.05 0.877 14.91 0.000 NA 16.00 6.32

Biotechnology & Drugs EXEG eXegenics Inc. OTC Healthcare 7.320 NA NA 0.45 0.80 NA 16.267 15.300 4.90 0.027 5.95 0.000 NA NA 58.41





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BioTech Industry 30Nov05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider Insider Net to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Shrs Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Purchased Yield (%) Quarterly Quarterly

Biotechnology & Drugs EXEL Exelixis, Inc. NASD Healthcare 676.690 NA NA 8.14 11.58 NA 83.131 58.500 81.03 7.986 29.63 -0.301 NA 258.85 2.42

Biotechnology & Drugs FVRL Favrille, Inc. NASD Healthcare 71.137 NA NA 3.50 1.60 NA 20.325 7.700 8.23 -0.033 62.12 0.000 NA 14.00 6.70

Biotechnology & Drugs FHRX First Horizon Pharmaceutical Corp. NASD Healthcare 632.218 0.59 25.33 17.97 1.90 20.31 35.182 28.200 95.00 2.501 19.84 0.000 NA 45.04 7.19

Biotechnology & Drugs FLML Flamel Technologies S.A. (ADR) NASD Healthcare 452.092 NA NA 19.29 NA NA 23.437 22.700 62.14 3.850 3.14 0.000 NA NA NA

Biotechnology & Drugs FMTI Forbes Medi-Tech Inc. (USA) NASD Healthcare 60.046 NA NA 1.75 2.72 NA 34.123 33.800 8.10 0.108 0.95 0.000 NA 3.56 2.81

Biotechnology & Drugs FRX Forest Laboratories, Inc. NYSE Healthcare 13,288.814 1.09 13.43 39.34 4.07 19.06 337.794 332.700 91.65 0.300 1.51 -0.720 NA NA 5.96

Biotechnology & Drugs GGEN GalaGen Inc. OTC Healthcare 0.025 NA NA 0.00 NA NA 12.275 7.500 0.00 -0.010 38.90 0.000 NA NA 0.37

Biotechnology & Drugs GCAN GammaCan International, Inc. OTC Healthcare 31.740 NA NA 1.21 32.70 NA 26.232 21.200 NA NA 19.18 NA NA NA 10.72

Biotechnology & Drugs GSAC GelStat Corporation OTC Healthcare 3.732 NA NA 0.25 2.25 NA 14.926 14.800 1.62 -0.003 0.84 0.000 NA 27.51 2.04

Biotechnology & Drugs GENR Genaera Corporation NASD Healthcare 99.586 NA NA 1.45 2.93 NA 68.680 68.600 18.39 2.702 0.12 0.000 NA NA 9.63

Biotechnology & Drugs GLGC Gene Logic Inc. NASD Healthcare 116.285 NA NA 3.66 0.92 NA 31.772 31.200 48.47 1.685 1.80 0.013 NA 0.69 2.95

Biotechnology & Drugs GNLB Genelabs Technologies NASD Healthcare 40.000 NA NA 0.45 8.82 NA 88.869 82.800 14.12 -0.867 6.83 0.000 NA NA 2.23

Biotechnology & Drugs GMXXE GeneMax Corporation OTC Healthcare 2.334 NA NA 0.08 NA NA 29.172 21.700 NA NA 25.61 NA NA NA 0.13

Biotechnology & Drugs DNA Genentech, Inc. NYSE Healthcare 102,941.500 1.57 34.07 97.62 13.33 91.82 1,054.512 454.700 39.42 -9.044 56.88 -1.546 NA 27.03 3.54

Biotechnology & Drugs GNBT Generex Biotechnology Corporation NASD Healthcare 45.894 NA NA 0.98 6.71 NA 46.831 39.700 1.34 -0.004 15.23 0.000 NA 80.43 0.24

Biotechnology & Drugs GBIW Genesis Bioventures, Inc. OTC Healthcare 3.373 NA NA 0.11 13.75 NA 30.660 20.500 0.01 -0.004 33.14 0.000 NA 1,442.56 0.03

Biotechnology & Drugs GTOP Genitope Corporation NASD Healthcare 224.324 NA 25.00 7.90 2.40 NA 28.395 24.500 0.00 0.000 13.72 0.000 NA 0.06 15.92

Biotechnology & Drugs GHDX Genomic Health, Inc. NASD Healthcare 229.768 NA 25.00 9.39 NA NA 24.469 5.017 6.96 1.703 79.50 0.175 NA 20.65 4.48

Biotechnology & Drugs GNTA Genta Incorporated NASD Healthcare 148.742 NA NA 1.30 5.68 4.85 114.417 111.500 12.36 1.820 2.55 0.100 NA 0.50 3.75

Biotechnology & Drugs GNT Gentium S.p.A. (ADR) AMEX Healthcare 65.168 NA NA 8.10 4.58 NA 8.059 2.000 6.47 0.502 75.19 0.000 NA 28.54 2.32

Biotechnology & Drugs GNVC GenVec, Inc. NASD Healthcare 104.899 NA NA 1.65 2.95 NA 63.575 46.500 20.46 3.127 26.86 0.000 NA 8.09 5.89

Biotechnology & Drugs GENZ Genzyme Corporation NASD Healthcare 19,338.563 1.41 19.14 74.89 3.88 132.40 258.226 232.700 90.08 8.961 9.89 -0.858 NA 17.01 2.67

Biotechnology & Drugs GORX GeoPharma, Inc. NASD Healthcare 27.540 NA NA 3.06 1.64 NA 9.000 5.500 21.18 -0.085 38.89 -0.120 NA 18.83 2.63

Biotechnology & Drugs GERN Geron Corporation NASD Healthcare 594.994 NA NA 9.18 2.64 NA 64.814 61.700 34.85 11.144 4.80 -0.121 NA 0.78 23.27

Biotechnology & Drugs GILD Gilead Sciences, Inc. NASD Healthcare 24,265.105 1.11 22.85 52.99 9.26 38.77 457.919 453.600 87.70 0.377 0.94 -0.873 NA 0.02 8.58

Biotechnology & Drugs GLIAQ Gliatech Inc. OTC Healthcare 0.001 NA NA 0.00 NA NA 9.683 7.800 0.05 0.000 19.45 0.000 NA NA 0.90

Biotechnology & Drugs GLGS GlycoGenesys, Inc. NASD Healthcare 7.086 NA NA 0.55 2.38 NA 12.884 10.200 3.45 0.124 20.83 0.000 NA NA 1.97

Biotechnology & Drugs GPCB GPC Biotech AG (ADR) NASD Healthcare 326.197 NA NA 10.85 2.81 NA 30.117 27.100 1.05 0.019 10.02 0.000 NA 1.77 7.47

Biotechnology & Drugs GTCB GTC Biotherapeutics, Inc. NASD Healthcare 96.834 NA NA 1.88 3.29 NA 51.508 44.800 15.21 1.040 13.02 0.005 NA 39.99 1.42

Biotechnology & Drugs GTXI GTx, Inc. NASD Healthcare 237.093 NA NA 7.65 5.32 NA 30.993 9.700 16.95 -0.295 68.70 1.340 NA 0.06 4.56

Biotechnology & Drugs HTI Halozyme Therapeutics, Inc. AMEX Healthcare 90.082 NA NA 1.80 16.22 NA 50.046 45.700 14.40 -0.344 8.68 0.023 NA NA 3.83

Biotechnology & Drugs HBX Hana Biosciences, Inc. AMEX Healthcare 131.458 NA NA 5.93 18.42 NA 22.168 16.400 2.36 0.524 26.02 0.133 NA NA 7.20

Biotechnology & Drugs VGENQ Harvard Scientific Corp. OTC Healthcare 0.003 NA NA 0.00 NA NA 29.326 5.900 NA NA 79.88 NA NA NA NA

Biotechnology & Drugs HDVY Health Discovery Corporation OTC Healthcare 22.672 NA NA 0.20 9.09 NA 113.358 75.900 NA NA 33.04 NA NA 66.76 0.46

Biotechnology & Drugs HESG Health Sciences Group, Inc. OTC Healthcare 13.303 NA NA 0.55 NA NA 24.188 12.300 NA NA 49.15 NA NA NA 0.35

Biotechnology & Drugs HCTL Healthcare Technologies NASD Healthcare 4.622 NA NA 0.60 NA NA 7.703 2.800 0.81 0.041 63.65 0.000 NA NA NA

Biotechnology & Drugs HXBM Helix BioMedix, Inc. OTC Healthcare 19.181 NA NA 0.95 4.46 NA 20.191 17.000 0.18 0.008 15.80 0.000 NA NA 24.69

Biotechnology & Drugs HEMA HemaCare Corporation OTC Healthcare 13.360 NA NA 1.63 2.10 10.64 8.196 7.900 0.93 -0.016 3.61 0.080 NA 1.89 2.12

Biotechnology & Drugs HMGN Hemagen Diagnostics, Inc. OTC Healthcare 2.813 NA NA 0.19 NA NA 15.204 12.400 0.29 -0.020 18.44 0.031 NA NA 1.89

Biotechnology & Drugs HEB Hemispherx BioPharma, Inc AMEX Healthcare 141.664 NA NA 2.62 10.31 NA 54.070 46.500 3.24 -0.782 14.00 0.039 NA 35.99 2.39

Biotechnology & Drugs HMSL Hemosol Corp. (USA) NASD Healthcare 1.373 NA NA 0.09 0.03 NA 15.171 13.500 13.34 0.754 11.01 0.000 NA 35.23 2.57

Biotechnology & Drugs HSKA Heska Corporation NASD Healthcare 63.439 NA NA 1.27 33.42 NA 49.952 29.200 37.91 0.469 41.54 -0.074 NA 735.72 1.24

Biotechnology & Drugs HITK Hi-Tech Pharmacal Co. NASD Healthcare 304.638 NA NA 38.66 4.25 37.67 7.880 7.000 49.54 0.288 11.17 -0.254 NA NA 5.32

Biotechnology & Drugs HEPH Hollis-Eden Pharmaceuticals Inc. NASD Healthcare 113.724 NA 50.00 5.49 2.31 NA 20.715 18.900 24.13 -0.518 8.76 -0.022 NA NA 12.73

Biotechnology & Drugs HSP Hospira, Inc. NYSE Healthcare 7,125.777 2.61 7.75 44.30 5.49 27.43 160.853 159.200 68.38 0.569 1.03 0.023 NA 53.86 2.49

Biotechnology & Drugs HBSC Human BioSystems OTC Healthcare 30.276 NA NA 0.57 NA NA 53.586 53.300 0.00 0.000 0.53 -0.258 NA NA 0.37

Biotechnology & Drugs HGSI Human Genome Sciences NASD Healthcare 1,229.168 NA NA 9.38 2.56 NA 131.041 128.100 95.00 10.480 2.24 0.000 NA 125.24 11.01

Biotechnology & Drugs ICGN Icagen, Inc. NASD Healthcare 135.564 NA 0.00 6.18 3.48 NA 21.936 16.500 19.52 0.263 24.78 0.005 NA 5.23 8.99

Biotechnology & Drugs ICLR ICON plc (ADR) NASD Healthcare 597.425 0.79 20.00 42.70 2.50 48.09 13.991 11.300 73.93 0.420 19.23 0.000 NA 0.09 2.28

Biotechnology & Drugs ICOR Icoria, Inc. OTC Healthcare 10.086 NA NA 0.26 1.34 NA 39.552 36.400 0.27 -0.314 7.85 0.000 NA 77.81 1.32

Biotechnology & Drugs ICOS ICOS Corporation NASD Healthcare 1,841.759 5.19 25.50 28.72 NA NA 64.128 63.800 73.60 4.188 0.51 -0.017 NA NA 7.88

Biotechnology & Drugs IDBE ID Biomedical Corporation (USA) NASD Healthcare 1,313.721 NA NA 29.58 16.47 NA 44.167 42.800 29.07 5.256 3.10 0.000 NA 95.94 0.91

Biotechnology & Drugs IDIX Idenix Pharmaceuticals, Inc. NASD Healthcare 1,047.006 NA NA 18.82 11.12 NA 55.633 15.700 20.71 0.889 71.78 3.310 NA 3.37 3.92

Biotechnology & Drugs IDP Idera Pharmaceuticals Inc. AMEX Healthcare 76.694 NA NA 0.69 22.26 NA 111.150 91.200 5.22 5.799 17.95 0.013 NA 146.54 3.39

Biotechnology & Drugs IDXX IDEXX Laboratories, Inc. NASD Healthcare 2,306.047 2.03 14.25 71.94 6.08 32.85 32.055 32.000 93.99 0.519 0.17 -0.073 NA 0.14 3.07

Biotechnology & Drugs IDMI IDM Pharma Inc. NASD Healthcare 62.198 NA NA 3.97 2.30 NA 15.694 9.700 1.61 0.258 38.19 3.329 NA 1.01 3.96

Biotechnology & Drugs IG IGI, Inc. AMEX Healthcare 9.687 NA NA 0.80 2.42 NA 12.109 8.300 3.71 -0.003 31.46 0.133 NA NA 1.89

Biotechnology & Drugs IMCL ImClone Systems Incorporated NASD Healthcare 2,717.918 1.65 10.66 32.37 9.99 39.38 83.964 69.400 60.73 -2.616 17.35 -0.073 NA 220.80 4.41

Biotechnology & Drugs ICRP IMCOR Pharmaceutical Co. OTC Healthcare 0.892 NA NA 0.18 0.49 NA 4.956 2.500 NA NA 49.56 NA NA 10.44 0.09

Biotechnology & Drugs IMM Immtech International, Inc. AMEX Healthcare 94.086 NA NA 8.06 NA NA 11.673 8.900 9.87 0.180 23.76 0.011 NA NA 0.93

Biotechnology & Drugs ICCC ImmuCell Corporation NASD Healthcare 14.695 NA NA 5.16 1.77 32.64 2.848 2.400 0.21 -0.003 15.73 0.000 NA NA 7.72

Biotechnology & Drugs IMMFF Immune Network Ltd. OTC Healthcare 0.368 NA NA 0.02 NA NA 20.918 12.800 NA NA 38.81 NA NA NA 0.05

Biotechnology & Drugs IMGN ImmunoGen, Inc. NASD Healthcare 237.017 NA NA 5.77 2.86 NA 41.077 40.600 40.22 0.927 1.16 0.000 NA NA 10.20

Biotechnology & Drugs IMMU Immunomedics, Inc. NASD Healthcare 111.066 NA NA 2.05 NA NA 54.073 44.500 22.27 -0.422 17.70 -0.500 NA NA 2.89

Biotechnology & Drugs IPXL Impax Laboratories Inc. OTC Healthcare 570.226 0.91 32.17 9.75 6.61 1,206.68 58.485 40.000 28.25 -25.540 31.61 0.000 NA 125.32 4.43





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BioTech Industry 30Nov05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider Insider Net to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Shrs Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Purchased Yield (%) Quarterly Quarterly

Biotechnology & Drugs INCY Incyte Corporation NASD Healthcare 494.691 NA 15.00 5.93 141.19 NA 83.422 75.900 70.03 -8.064 9.02 0.003 NA 9,727.42 13.59

Biotechnology & Drugs IDEV Indevus Pharmaceuticals NASD Healthcare 188.965 NA NA 4.02 NA NA 47.006 40.800 30.47 -2.274 13.20 0.040 NA NA 4.14

Biotechnology & Drugs INHX Inhibitex, Inc. NASD Healthcare 258.945 NA NA 8.57 2.85 NA 30.215 12.600 28.16 3.322 58.30 0.000 NA 6.51 8.84

Biotechnology & Drugs ISV Insite Vision Inc. AMEX Healthcare 74.972 NA NA 0.95 158.33 NA 78.918 68.900 10.14 -0.171 12.69 0.000 NA 67.42 1.12

Biotechnology & Drugs INSM Insmed Incorporated NASD Healthcare 68.032 NA NA 1.25 10.68 NA 54.425 50.600 13.09 0.521 7.03 0.000 NA 230.60 5.25

Biotechnology & Drugs ISPH Inspire Pharmaceuticals, Inc. NASD Healthcare 313.565 NA 30.00 7.43 2.50 NA 42.203 41.600 93.73 4.990 1.43 0.000 NA 1.21 12.14

Biotechnology & Drugs INB Integrated BioPharma, Inc. AMEX Healthcare 48.967 NA NA 3.86 3.44 NA 12.686 7.600 2.83 -0.013 40.09 0.000 NA 32.80 1.96

Biotechnology & Drugs IFSC Interferon Sciences, Inc. OTC Healthcare 8.028 NA NA 0.22 14.33 NA 37.339 20.900 0.60 -0.010 44.03 0.000 NA 39.20 1.68

Biotechnology & Drugs ITMN InterMune, Inc. NASD Healthcare 482.526 NA NA 14.76 NA NA 32.691 25.500 83.21 -0.163 22.00 0.000 NA NA 3.08

Biotechnology & Drugs INIS International Isotopes Inc. OTC Healthcare 14.140 NA NA 0.08 15.40 NA 183.634 115.000 0.00 0.000 37.38 0.650 NA 137.01 1.13

Biotechnology & Drugs IPA Interpharm Holdings, Inc. AMEX Healthcare 45.921 NA NA 1.42 1.98 NA 32.339 23.100 2.14 -0.093 28.57 -0.122 NA 73.69 1.11

Biotechnology & Drugs IBCL Int'l BioChemical Industries, Inc. OTC Healthcare 0.009 NA NA 0.00 NA NA 94.162 92.500 0.01 0.000 1.76 0.000 NA NA 0.02

Biotechnology & Drugs IBPI IntraBiotics Pharmaceuticals OTC Healthcare 33.562 NA NA 3.62 0.71 NA 9.271 7.400 57.83 0.407 20.18 0.140 NA NA 137.37

Biotechnology & Drugs INGN Introgen Therapeutics, Inc NASD Healthcare 230.950 NA NA 6.22 13.95 NA 37.130 24.500 26.64 0.327 34.02 -0.687 NA 57.68 3.52

Biotechnology & Drugs IMA Inverness Medical Innovations, Inc. AMEX Healthcare 658.296 NA NA 24.05 1.62 NA 27.372 22.200 59.96 5.886 18.90 -0.011 NA 61.11 1.60

Biotechnology & Drugs IVRO InVitro International OTC Healthcare 0.348 NA NA 0.02 0.86 26.67 14.507 9.000 NA NA 37.96 NA NA NA 9.37

Biotechnology & Drugs IVGN Invitrogen Corporation NASD Healthcare 3,602.368 1.10 15.56 68.16 1.78 33.13 52.852 52.400 95.00 0.374 0.86 -0.300 NA 75.42 6.92

Biotechnology & Drugs IOX IOMED, Inc. AMEX Healthcare 20.683 NA NA 2.90 5.97 58.17 7.132 5.900 5.89 0.070 17.27 0.000 NA 11.87 7.38

Biotechnology & Drugs ISIS ISIS Pharmaceuticals, Inc. NASD Healthcare 376.170 NA NA 5.21 93.04 NA 72.201 64.400 49.74 6.054 10.81 -0.013 NA 3,902.45 4.78

Biotechnology & Drugs ILE Isolagen, Inc. AMEX Healthcare 49.929 NA 15.00 1.65 21.43 NA 30.260 28.400 29.64 -3.385 6.15 0.024 NA 3,867.64 9.48

Biotechnology & Drugs ISTA ISTA Pharmaceuticals NASD Healthcare 178.479 NA 26.67 6.90 4.36 NA 25.867 18.800 95.00 2.217 27.32 -0.136 NA 0.12 6.69

Biotechnology & Drugs ITER IT&E International Group OTC Healthcare 4.482 NA NA 0.21 7.50 NA 21.344 10.200 NA NA 52.21 NA NA 471.24 1.52

Biotechnology & Drugs ITXFF Iteration Energy, Ltd. (USA) OTC Healthcare 211.816 NA NA 4.31 1.83 NA 48.829 45.400 0.41 0.200 7.02 0.000 NA 1.03 2.31

Biotechnology & Drugs IVX IVAX Corporation AMEX Healthcare 8,225.402 0.96 22.55 30.05 4.65 42.87 273.724 156.300 56.69 -22.879 42.90 -0.145 NA 79.44 1.52

Biotechnology & Drugs KNDL Kendle International Inc. NASD Healthcare 348.322 NA NA 24.81 2.98 37.91 14.040 11.600 64.56 1.256 17.38 0.000 NA 4.68 2.25

Biotechnology & Drugs KERX Keryx Biopharmaceuticals NASD Healthcare 530.402 NA 25.00 14.07 5.14 NA 37.697 31.100 76.96 8.857 17.50 -0.031 NA NA 18.82

Biotechnology & Drugs KG King Pharmaceuticals NYSE Healthcare 3,805.837 2.26 6.21 15.74 1.85 16.90 241.794 239.900 79.84 10.315 0.78 0.000 NA 16.73 2.17

Biotechnology & Drugs KOSP KOS Pharmaceuticals, Inc. NASD Healthcare 3,139.474 0.94 21.78 67.60 4.97 21.40 46.442 18.000 41.02 0.972 61.24 -0.527 NA 0.04 2.72

Biotechnology & Drugs KOSN Kosan Biosciences Incorporated NASD Healthcare 211.738 NA NA 7.21 4.44 NA 29.367 22.800 57.47 2.763 22.36 0.000 NA 8.35 4.76

Biotechnology & Drugs KV.A K-V Pharmaceutical Company NYSE Healthcare 1,006.974 0.90 21.50 20.41 3.56 ####### 49.337 36.300 56.19 -1.189 26.42 -0.294 NA 74.42 8.00

Biotechnology & Drugs LJPC La Jolla Pharmaceutical Company NASD Healthcare 48.941 NA NA 0.66 2.39 NA 74.153 73.700 12.98 -0.043 0.61 0.000 NA 4.26 4.89

Biotechnology & Drugs LCI Lannett Company, Inc. AMEX Healthcare 179.014 NA NA 7.42 2.51 NA 24.126 10.100 4.07 -0.058 58.14 0.011 NA 12.60 2.04

Biotechnology & Drugs LSBC Large Scale Biology Corp. NASD Healthcare 9.672 NA NA 0.30 10.35 NA 32.240 25.200 2.97 -1.419 21.84 0.000 NA 668.70 0.10

Biotechnology & Drugs LCAR Lescarden Inc. OTC Healthcare 9.272 NA NA 0.30 NA 24.79 30.907 15.800 0.05 0.000 48.88 0.000 NA NA 1.01

Biotechnology & Drugs LEXG Lexicon Genetics Incorporated NASD Healthcare 257.503 NA NA 3.99 3.23 NA 64.537 58.300 53.89 0.920 9.66 -0.275 NA 46.49 1.97

Biotechnology & Drugs LSRI Life Sciences Research Inc. OTC Healthcare 144.362 0.43 25.00 11.50 56.65 12.12 12.553 9.400 2.26 -1.358 25.12 0.000 NA 2,994.18 0.56

Biotechnology & Drugs LIFC LifeCell Corporation NASD Healthcare 599.305 0.87 39.50 18.31 6.97 48.70 32.731 32.600 76.38 1.967 0.40 0.000 NA NA 6.29

Biotechnology & Drugs LCBM Lifecore Biomedical, Inc. NASD Healthcare 196.685 1.11 21.83 14.95 2.79 11.70 13.156 11.800 55.00 -0.742 10.31 0.002 NA 7.59 6.95

Biotechnology & Drugs LGND Ligand Pharmaceuticals OTC Healthcare 830.641 NA 36.10 11.21 NA NA 74.131 69.700 40.07 -28.308 5.98 0.000 NA NA 0.80

Biotechnology & Drugs LIPD Lipid Sciences, Inc. NASD Healthcare 76.606 NA NA 2.80 4.78 NA 27.359 19.000 6.20 0.628 30.55 -0.250 NA NA 6.49

Biotechnology & Drugs LRP Lorus Therapeutics Inc. (USA) AMEX Healthcare 38.228 NA NA 0.22 5.59 NA 172.805 164.200 3.88 1.763 4.98 0.000 NA 129.76 4.45

Biotechnology & Drugs LMNX Luminex Corporation NASD Healthcare 337.228 NA NA 10.66 7.44 NA 31.635 28.400 40.40 0.485 10.23 0.003 NA NA 8.09

Biotechnology & Drugs MCHM MacroChem Corporation OTC Healthcare 1.256 NA NA 0.03 0.33 NA 41.863 40.900 NA NA 2.30 NA NA NA 5.65

Biotechnology & Drugs MHA Manhattan Pharmaceuticals, Inc. AMEX Healthcare 72.108 NA NA 1.20 6.32 NA 60.090 35.300 1.00 -1.278 41.26 0.015 NA NA 7.13

Biotechnology & Drugs MTEX Mannatech, Inc. NASD Healthcare 344.766 NA NA 12.81 5.30 15.33 26.914 16.400 21.38 1.328 39.06 -0.203 2.50 0.04 1.76

Biotechnology & Drugs MNKD MannKind Corporation NASD Healthcare 648.024 NA NA 12.90 2.69 NA 50.234 25.500 22.41 6.010 49.24 8.567 NA NA 9.87

Biotechnology & Drugs MSHL Marshall Edwards, Inc. NASD Healthcare 434.437 NA NA 7.63 29.57 NA 56.938 6.800 0.84 -0.140 88.06 0.000 NA NA 4.81

Biotechnology & Drugs MATK Martek Biosciences Corp. NASD Healthcare 859.812 0.97 31.67 27.11 1.89 18.18 31.716 30.500 95.00 2.105 3.83 -0.283 NA 16.23 4.43

Biotechnology & Drugs MZT Matritech, Inc. AMEX Healthcare 28.886 NA NA 0.62 10.33 NA 46.590 45.800 5.86 -0.166 1.70 0.010 NA 27.09 1.94

Biotechnology & Drugs MTXX Matrixx Initiatives, Inc. NASD Healthcare 213.824 0.74 31.33 22.30 4.19 28.03 9.589 8.800 50.81 0.597 8.23 -0.019 NA NA 3.31

Biotechnology & Drugs MAXM Maxim Pharmaceuticals NASD Healthcare 34.041 NA NA 1.19 1.07 NA 28.606 28.500 9.23 -0.306 0.37 0.000 NA 0.78 6.68

Biotechnology & Drugs MAXY Maxygen, Inc. NASD Healthcare 270.549 NA NA 7.54 1.34 NA 35.882 26.300 35.89 0.511 26.70 -0.068 NA 0.00 21.03

Biotechnology & Drugs MDZ MDS Inc. (USA) NYSE Healthcare 2,353.377 1.08 15.00 16.51 1.76 33.06 141.756 95.000 63.44 8.958 32.98 0.000 0.67 31.77 1.82

Biotechnology & Drugs MEDX Medarex, Inc. NASD Healthcare 1,180.343 NA NA 10.60 6.32 NA 111.353 110.100 61.16 4.877 1.13 -0.149 NA 80.29 8.61

Biotechnology & Drugs MLSC Medical Discoveries, Inc. OTC Healthcare 12.940 NA NA 0.12 NA NA 107.830 84.700 NA NA 21.45 NA NA NA 0.67

Biotechnology & Drugs MRX Medicis Pharmaceutical Corporation NYSE Healthcare 1,776.836 1.02 19.82 32.66 3.51 27.45 54.404 53.400 NA NA 1.85 0.000 0.37 89.60 8.14

Biotechnology & Drugs MCU Medicure Inc. (USA) AMEX Healthcare 86.194 NA NA 1.19 13.01 NA 72.032 64.100 2.01 -3.441 11.01 0.000 NA NA 3.90

Biotechnology & Drugs MHUT Medi-Hut Co., Inc. OTC Healthcare 1.447 NA NA 0.10 0.09 0.98 14.466 10.400 0.38 0.000 28.11 2.000 NA NA 2.66

Biotechnology & Drugs MEDI MedImmune, Inc. NASD Healthcare 8,882.689 2.81 28.65 36.10 5.58 172.05 246.058 244.700 87.51 2.973 0.55 -0.155 NA 31.80 0.81

Biotechnology & Drugs TOX MEDTOX Scientific, Inc. AMEX Healthcare 58.210 0.84 20.00 7.15 1.34 24.49 8.141 7.500 41.24 0.586 7.87 -0.023 NA 17.91 2.00

Biotechnology & Drugs MEMY Memory Pharmaceuticals Corp. NASD Healthcare 78.645 NA NA 2.11 3.32 NA 37.273 30.200 31.85 3.963 18.98 5.229 NA 10.72 3.61

Biotechnology & Drugs VIVO Meridian Bioscience, Inc. NASD Healthcare 462.387 1.57 16.25 19.26 NA 37.21 24.008 17.700 57.66 4.011 26.27 -1.817 1.66 NA NA

Biotechnology & Drugs MBRX Metabasis Therapeutics, Inc. NASD Healthcare 149.921 NA NA 5.94 4.11 NA 25.239 13.400 25.28 0.759 46.91 2.599 NA 8.76 4.86

Biotechnology & Drugs MOGN MGi Pharma, Inc. NASD Healthcare 1,492.000 0.62 53.70 19.26 8.73 41.45 77.466 77.100 90.67 4.326 0.47 -0.067 NA 163.50 8.30

Biotechnology & Drugs MLARE Micro Laboratories, Inc. OTC Healthcare 1.192 NA NA 0.02 NA 36.36 59.619 9.500 NA NA 84.07 NA NA NA 0.00





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BioTech Industry 30Nov05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider Insider Net to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Shrs Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Purchased Yield (%) Quarterly Quarterly

Biotechnology & Drugs MII MicroIslet, Inc. AMEX Healthcare 70.022 NA NA 1.74 19.55 NA 40.242 23.500 4.51 0.257 41.60 0.000 NA 2.81 3.67

Biotechnology & Drugs MLNM Millennium Pharmaceuticals, Inc. NASD Healthcare 3,293.891 55.17 15.00 10.61 1.54 NA 310.452 301.200 73.40 13.890 2.98 -1.111 NA 8.77 4.71

Biotechnology & Drugs MRVT Miravant Medical Technologies OTC Healthcare 10.134 NA NA 0.27 NA NA 37.533 35.900 2.67 -0.013 4.35 0.000 NA NA 2.54

Biotechnology & Drugs MNTA Momenta Pharmaceuticals, Inc. NASD Healthcare 700.338 NA NA 22.99 4.20 NA 30.463 15.600 57.33 9.059 48.79 -0.200 NA 1.67 28.87

Biotechnology & Drugs MGRM Monogram Biosciences Inc. NASD Healthcare 225.109 NA NA 1.77 3.57 NA 127.180 122.100 57.84 73.561 3.99 -0.017 NA 8.85 2.25

Biotechnology & Drugs MCET MultiCell Technologies, Inc. OTC Healthcare 21.826 NA NA 0.67 4.53 NA 32.576 22.900 0.00 0.000 29.70 -0.020 NA 0.00 7.16

Biotechnology & Drugs MYL Mylan Laboratories Inc. NYSE Healthcare 4,500.510 1.04 16.55 20.92 7.70 36.06 215.130 180.400 53.39 -55.506 16.14 -0.771 1.15 2.37 4.70

Biotechnology & Drugs MYMXE Mymetics Corporation OTC Healthcare 17.158 NA NA 0.10 NA NA 171.867 118.600 0.16 0.000 30.99 0.000 NA NA 0.02

Biotechnology & Drugs MYOG Myogen, Inc. NASD Healthcare 835.414 NA 18.00 20.12 4.63 NA 41.522 25.900 74.84 9.888 37.62 -0.941 NA 0.43 11.64

Biotechnology & Drugs MYGN Myriad Genetics, Inc. NASD Healthcare 608.571 NA NA 19.66 4.76 NA 30.955 11.100 65.44 -0.646 64.14 0.000 NA NA 5.70

Biotechnology & Drugs NABI Nabi Biopharmaceuticals NASD Healthcare 201.882 NA 10.00 3.40 0.85 NA 59.377 59.000 84.38 0.331 0.63 0.017 NA 51.87 3.47

Biotechnology & Drugs NSTK Nastech Pharmaceutical NASD Healthcare 298.620 NA NA 14.46 4.72 NA 20.651 14.400 41.85 2.542 30.27 -0.368 NA 7.66 7.87

Biotechnology & Drugs NHCT National Healthcare Technology, Inc. OTC Healthcare 27.620 NA NA 1.50 NA NA 18.414 8.500 NA NA 53.84 NA NA NA NA

Biotechnology & Drugs NTOL Natrol, Inc. NASD Healthcare 25.694 NA NA 1.90 0.68 84.97 13.523 6.700 42.45 0.195 50.46 -0.022 NA 21.12 3.40

Biotechnology & Drugs NAII Natural Alternatives International, Inc. NASD Healthcare 35.446 NA NA 5.87 1.29 21.69 6.039 4.900 7.22 -0.001 18.86 0.100 NA 13.27 2.30

Biotechnology & Drugs NAWL Naturewell, Inc. OTC Healthcare 0.437 NA NA 0.00 NA NA 118.221 72.100 0.00 0.000 39.01 0.000 NA NA 0.07

Biotechnology & Drugs NTY NBTY, Inc. NYSE Healthcare 1,329.652 0.85 13.67 19.79 1.88 15.59 67.188 56.600 74.55 -2.354 15.76 -0.100 NA 42.15 3.00

Biotechnology & Drugs NEOG Neogen Corporation NASD Healthcare 165.098 1.24 16.50 20.08 2.88 26.27 8.222 7.100 25.94 0.085 13.65 -0.057 NA NA 4.43

Biotechnology & Drugs NEOL NeoPharm, Inc. NASD Healthcare 218.882 NA 0.00 9.22 6.99 NA 23.740 18.900 70.38 0.257 20.39 0.028 NA NA 4.04

Biotechnology & Drugs NEOP Neoprobe Corporation OTC Healthcare 15.242 NA NA 0.26 2.86 NA 58.623 53.400 0.40 0.019 8.91 0.024 NA 1.34 8.71

Biotechnology & Drugs NERX NeoRx Corporation NASD Healthcare 33.293 NA NA 0.97 4.57 NA 34.322 31.800 5.62 -0.092 7.35 0.000 NA 55.37 2.21

Biotechnology & Drugs NTEC Neose Technologies, Inc. NASD Healthcare 59.008 NA 0.00 1.80 1.24 NA 32.782 30.800 54.74 -0.433 6.05 0.000 NA 33.50 4.36

Biotechnology & Drugs NTII Neurobiological Tech. NASD Healthcare 108.604 NA NA 4.01 11.69 NA 27.083 14.100 25.88 -0.040 47.94 0.000 NA NA 1.38

Biotechnology & Drugs NRMX Neurochem Inc. (USA) NASD Healthcare 465.935 NA NA 13.40 8.87 NA 34.579 22.600 21.43 0.263 34.64 0.000 NA 14.49 3.89

Biotechnology & Drugs NBIX Neurocrine Biosciences, Inc. NASD Healthcare 2,195.712 2.96 25.00 59.46 5.43 NA 36.928 35.800 95.00 2.949 3.06 -0.100 NA 15.11 8.49

Biotechnology & Drugs NRGN Neurogen Corporation NASD Healthcare 259.721 NA NA 7.51 2.08 NA 34.583 26.000 37.79 0.141 24.82 0.000 NA 9.79 11.00

Biotechnology & Drugs NRGX Neurologix, Inc. OTC Healthcare 49.086 NA NA 1.85 7.97 NA 26.533 15.900 27.47 0.000 40.08 0.000 NA 0.32 24.17

Biotechnology & Drugs NRPH New River Pharmaceuticals, Inc. NASD Healthcare 882.921 NA NA 48.66 1,131.63 NA 18.145 6.200 29.27 1.692 65.83 -0.907 NA 6.87 11.22

Biotechnology & Drugs BBAL New York Health Care, Inc. OTC Healthcare 28.248 NA NA 0.85 3.81 NA 33.233 32.600 NA NA 1.90 NA NA NA 1.23

Biotechnology & Drugs NEXM NexMed, Inc. NASD Healthcare 61.074 NA NA 1.12 19.65 NA 54.530 52.300 11.33 -4.495 4.09 0.005 NA 144.60 1.50

Biotechnology & Drugs NTMD NitroMed, Inc. NASD Healthcare 484.024 NA 0.00 15.88 7.54 NA 30.480 17.100 84.46 5.317 43.90 -0.060 NA 28.65 3.03

Biotechnology & Drugs NASI North American Scientific, Inc. NASD Healthcare 40.201 NA NA 2.40 0.73 NA 16.751 14.100 35.99 -1.164 15.83 0.007 NA NA 1.47

Biotechnology & Drugs NFLD Northfield Laboratories NASD Healthcare 341.112 NA 10.00 12.75 3.79 NA 26.754 24.500 21.17 -0.059 8.43 0.000 NA NA 27.92

Biotechnology & Drugs NWBT Northwest Biotherapeutics OTC Healthcare 2.671 NA NA 0.14 NA NA 19.078 18.900 0.00 0.000 0.93 0.000 NA NA 0.04

Biotechnology & Drugs NVAX Novavax, Inc. NASD Healthcare 180.722 NA NA 3.68 8.11 NA 49.111 42.300 10.18 0.541 13.87 -1.576 NA 181.96 2.27

Biotechnology & Drugs NOVN Noven Pharmaceuticals, Inc. NASD Healthcare 263.591 0.59 34.00 11.17 1.96 40.60 23.598 22.700 85.61 0.534 3.81 -0.003 NA 0.11 3.99

Biotechnology & Drugs NVO Novo Nordisk A/S (ADR) NYSE Healthcare 19,473.104 1.59 10.71 54.99 4.67 18.46 354.694 261.800 2.46 -0.360 26.19 0.000 1.56 8.02 1.95

Biotechnology & Drugs NVGN Novogen Limited (ADR) NASD Healthcare 392.804 NA NA 20.09 9.27 NA 19.420 17.480 3.93 -0.016 9.99 0.000 NA 1.35 8.48

Biotechnology & Drugs NPSP NPS Pharmaceuticals, Inc. NASD Healthcare 554.324 NA NA 12.06 NA NA 45.964 44.800 84.14 5.335 2.53 0.006 NA NA 7.51

Biotechnology & Drugs NPHCE Nutra Pharma Corp. OTC Healthcare 11.944 NA NA 0.18 175.00 NA 68.252 60.700 NA NA 11.06 NA NA NA 0.20

Biotechnology & Drugs NUTR Nutraceutical Int'l Corp. NASD Healthcare 146.186 NA NA 12.75 1.86 11.79 11.466 10.900 71.87 0.062 4.94 0.000 NA 6.32 3.08

Biotechnology & Drugs NXXI Nutrition 21, Inc. NASD Healthcare 26.502 NA NA 0.69 2.77 NA 38.409 32.800 2.08 0.026 14.60 0.000 NA NA 2.86

Biotechnology & Drugs NUVO Nuvelo, Inc. NASD Healthcare 367.490 NA 0.00 8.69 5.74 NA 42.289 41.500 64.10 0.309 1.87 0.000 NA 20.57 2.31

Biotechnology & Drugs NXTM NxStage Medical, Inc. NASD Healthcare 266.528 NA NA 13.20 NA NA 20.192 5.500 0.00 0.000 72.76 0.699 NA 48.29 2.27

Biotechnology & Drugs NYMX Nymox Pharmaceutical Corporation NASD Healthcare 59.543 NA NA 2.25 83.33 NA 26.464 12.700 0.51 -0.003 52.01 0.000 NA 68.97 0.17

Biotechnology & Drugs OMDI OmniMed International, Inc. OTC Healthcare 6.248 NA NA 12.00 NA NA 0.521 0.020 NA NA 96.16 NA NA NA 0.08

Biotechnology & Drugs ONCY Oncolytics Biotech, Inc. (USA) NASD Healthcare 139.524 NA NA 4.20 4.92 NA 33.037 32.700 11.12 0.078 1.02 0.000 NA 0.46 20.42

Biotechnology & Drugs ONCR Oncor, Inc. OTC Healthcare 0.013 NA NA 0.00 NA NA 33.554 24.500 0.15 0.000 26.98 0.000 NA NA 5.83

Biotechnology & Drugs ONXX Onyx Pharmaceuticals, Inc. NASD Healthcare 912.387 NA 25.00 25.78 7.33 NA 35.391 32.900 89.61 0.704 7.04 0.000 NA 24.09 6.53

Biotechnology & Drugs ONI Oragenics, Inc. AMEX Healthcare 10.038 NA NA 0.66 7.25 NA 15.209 7.600 2.47 0.040 50.03 0.000 NA NA 1.29

Biotechnology & Drugs ORCH Orchid Cellmark, Inc. NASD Healthcare 169.347 NA 30.00 6.90 3.37 NA 24.543 24.500 50.42 2.385 0.17 0.002 NA 0.00 2.78

Biotechnology & Drugs ORCY Organic Recycling Technologies Inc. OTC Healthcare 9.943 NA NA 0.45 NA NA 22.095 20.300 NA NA 8.12 NA NA NA 0.14

Biotechnology & Drugs ORGT OrganiTECH USA, Inc. OTC Healthcare 4.456 NA NA 0.21 NA NA 21.218 6.800 NA NA 67.95 NA NA NA 0.34

Biotechnology & Drugs OSCI Oscient Pharmaceuticals Corporation NASD Healthcare 150.184 NA 30.00 1.95 3.33 NA 77.018 68.200 38.14 0.513 11.45 -4.062 NA 387.95 5.04

Biotechnology & Drugs OSIP OSI Pharmaceuticals, Inc. NASD Healthcare 1,358.156 NA 23.33 23.83 2.57 NA 56.994 54.300 85.89 -4.468 4.73 -0.012 NA 31.44 14.04

Biotechnology & Drugs OXGN OXiGENE, Inc. NASD Healthcare 96.232 NA NA 4.68 2.79 NA 20.563 19.900 11.18 0.046 3.22 0.150 NA NA 9.70

Biotechnology & Drugs OXIS OXIS International, Inc. OTC Healthcare 11.439 NA NA 0.27 2.09 NA 42.368 11.200 0.27 0.085 73.57 0.000 NA 0.00 7.14

Biotechnology & Drugs PBME Pacific Biometrics, Inc. OTC Healthcare 14.790 NA NA 1.16 NA NA 12.750 9.000 0.23 0.029 29.41 -0.316 NA NA 1.13

Biotechnology & Drugs PHLI PacificHealth Laboratories, Inc. OTC Healthcare 1.075 NA NA 0.11 NA NA 10.237 8.000 0.00 0.000 21.85 0.000 NA 1,011.86 0.98

Biotechnology & Drugs PTIE Pain Therapeutics, Inc. NASD Healthcare 316.364 NA NA 7.21 4.78 NA 43.878 30.100 42.72 0.402 31.40 0.061 NA NA 9.44

Biotechnology & Drugs PTN Palatin Technologies, Inc. AMEX Healthcare 226.267 NA NA 3.85 16.74 NA 58.771 52.500 17.41 0.557 10.67 0.012 NA 0.21 2.37

Biotechnology & Drugs PGNT Paligent Inc. OTC Healthcare 0.975 NA NA 0.03 NA 6.96 32.491 14.900 0.05 0.000 54.14 0.000 NA NA 0.26

Biotechnology & Drugs PANC Panacos Pharmaceuticals, Inc. NASD Healthcare 378.465 NA NA 7.69 30.40 NA 49.215 26.800 36.92 12.668 45.54 -3.325 NA 5.20 2.06

Biotechnology & Drugs PRX Par Pharmaceutical Companies, Inc NYSE Healthcare 919.479 1.66 12.17 26.85 1.99 29.88 34.245 34.100 95.00 2.588 0.42 0.015 NA 43.69 4.36

Biotechnology & Drugs PRXL PAREXEL International Corporation NASD Healthcare 555.976 1.17 17.50 20.89 2.62 NA 26.614 26.300 95.00 1.346 1.18 0.001 NA 0.76 1.55





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 30Nov05 6 of 45 10/24/2011 3:30 PM

BioTech Industry 30Nov05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider Insider Net to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Shrs Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Purchased Yield (%) Quarterly Quarterly

Biotechnology & Drugs PPRX Peninsula Pharmaceuticals, Inc. NASD Healthcare NA NA NA NA NA NA NA NA NA NA 100.00 NA NA NA NA

Biotechnology & Drugs PPCO Penwest Pharmaceuticals NASD Healthcare 391.643 NA NA 17.92 6.01 NA 21.855 21.800 81.37 2.316 0.25 -0.031 NA NA 12.78

Biotechnology & Drugs PPHM Peregrine Pharmaceuticals NASD Healthcare 162.697 NA NA 0.98 9.80 NA 166.018 164.300 7.06 -1.165 1.03 0.235 NA 5.28 5.09

Biotechnology & Drugs PRGO Perrigo Company NASD Healthcare 1,390.905 1.73 8.57 14.89 2.34 NA 93.412 77.100 72.34 4.837 17.46 0.000 1.14 116.45 1.84

Biotechnology & Drugs PHFRQ Pharmaceutical Formulations, Inc. OTC Healthcare 0.603 NA NA 0.01 NA NA 86.161 83.300 NA NA 3.32 NA NA NA 0.69

Biotechnology & Drugs PPDI NASD

Pharmaceutical Product Development, Inc. Healthcare 3,346.505 1.16 19.20 57.90 4.41 27.14 57.798 49.100 77.94 0.786 15.05 -0.693 0.34 1.03 2.04

Biotechnology & Drugs PCOP Pharmacopeia Drug Discovery, Inc. NASD Healthcare 47.159 NA NA 3.15 1.24 NA 14.971 14.400 69.21 1.680 3.81 0.006 NA NA 3.84

Biotechnology & Drugs PCYC Pharmacyclics, Inc. NASD Healthcare 148.237 NA NA 7.47 2.41 NA 19.844 18.300 75.71 1.581 7.78 0.000 NA NA 12.06

Biotechnology & Drugs PFTR PharmaFrontiers Corp. OTC Healthcare 15.045 NA NA 0.73 0.49 NA 20.610 14.900 0.00 0.000 27.70 0.023 NA 5.00 2.14

Biotechnology & Drugs PPRT PharmaPrint Inc. OTC Healthcare 0.002 NA NA 0.00 NA NA 23.984 22.500 NA NA 6.19 NA NA NA 0.06

Biotechnology & Drugs PHRM Pharmion Corporation NASD Healthcare 593.781 0.53 33.75 18.63 1.63 28.85 31.872 26.500 75.50 1.931 16.85 -0.028 NA 0.00 6.74

Biotechnology & Drugs PARS Pharmos Corporation NASD Healthcare 38.626 NA NA 2.03 0.81 NA 19.028 18.700 6.09 0.062 1.72 0.000 NA 0.00 20.62

Biotechnology & Drugs PLTT Pilot Therapeutics Holdings, Inc. OTC Healthcare 0.750 NA NA 0.07 NA NA 11.545 2.600 NA NA 77.48 NA NA NA 0.25

Biotechnology & Drugs PLRS Pluristem Life Systems, Inc. OTC Healthcare 5.156 NA NA 0.08 2.89 NA 63.653 36.200 NA NA 43.13 NA NA 1.05 4.65

Biotechnology & Drugs POTP Point Therapeutics, Inc. OTC Healthcare 76.827 NA NA 3.27 5.22 NA 23.495 22.680 28.52 -0.059 3.47 0.035 NA 0.09 3.86

Biotechnology & Drugs POLXF Polydex Pharmaceuticals Limited NASD Healthcare 18.772 NA NA 6.15 2.31 NA 3.052 2.700 0.52 -0.008 11.53 0.000 NA 11.84 3.17

Biotechnology & Drugs PROAQ Polymer Research Corp. of America OTC Healthcare 0.532 NA NA 0.25 1.70 NA 2.129 0.900 0.14 0.000 57.73 0.000 NA 687.86 0.69

Biotechnology & Drugs PWRM Power3 Medical Products, Inc. OTC Healthcare 10.128 NA NA 0.16 NA NA 65.345 23.500 0.01 0.010 64.04 0.000 NA NA 0.02

Biotechnology & Drugs POZN POZEN Inc. NASD Healthcare 313.444 NA NA 10.84 17.68 NA 28.916 25.000 43.50 0.726 13.80 0.001 NA NA 2.43

Biotechnology & Drugs PRAI PRA International NASD Healthcare 648.908 1.28 14.50 28.49 3.60 23.21 22.777 12.100 71.32 1.535 46.88 -6.382 NA NA 1.27

Biotechnology & Drugs PRCS Praecis Pharmaceuticals NASD Healthcare 41.977 NA NA 4.00 0.80 NA 10.494 9.200 NA NA 12.33 NA NA 60.21 2.28

Biotechnology & Drugs PRAN Prana Biotechnology Limited (ADR) NASD Healthcare 19.353 NA NA 1.50 1.32 NA 12.814 5.720 3.75 -0.016 55.36 0.000 NA NA 8.35

Biotechnology & Drugs PME PreMD Inc. AMEX Healthcare 28.812 NA NA 1.33 13.19 NA 21.544 19.200 1.11 0.239 10.88 0.000 NA 223.36 9.11

Biotechnology & Drugs PBIO Pressure BioSciences, Inc. NASD Healthcare 11.149 NA NA 4.60 1.18 NA 2.424 2.400 0.62 -0.001 0.99 0.005 NA NA 5.12

Biotechnology & Drugs PGLAF Progen Industries Limited (USA) NASD Healthcare 80.850 NA NA 1.98 4.25 NA 40.557 38.100 0.93 0.014 6.06 0.000 NA NA 16.79

Biotechnology & Drugs PGNX Progenics Pharmaceuticals, Inc. NASD Healthcare 650.294 NA NA 26.55 5.10 NA 24.493 19.800 77.99 3.550 19.16 -0.034 NA NA 15.34

Biotechnology & Drugs PRW Pro-Pharmaceuticals, Inc. AMEX Healthcare 79.488 NA NA 2.91 14.92 NA 27.315 22.300 2.37 0.012 18.36 0.000 NA NA 5.06

Biotechnology & Drugs PDLI Protein Design Labs, Inc. NASD Healthcare 3,131.221 1.85 40.00 27.75 5.66 NA 112.837 109.300 95.00 11.721 3.13 -1.353 NA 90.71 3.32

Biotechnology & Drugs PPTI Protein Polymer Technologies, Inc. OTC Healthcare 16.816 NA NA 0.25 NA NA 67.262 34.900 0.01 0.000 48.11 0.000 NA 0.00 9.55

Biotechnology & Drugs PPMD Protide Pharmaceuticals OTC Healthcare 0.604 NA NA 0.15 2.54 NA 4.029 3.400 NA NA 15.61 NA NA 29.71 2.61

Biotechnology & Drugs PVCT Provectus Pharmaceuticals, Inc. OTC Healthcare 16.232 NA NA 0.95 1.79 NA 17.086 11.300 0.10 -0.008 33.86 0.000 NA 21.92 0.48

Biotechnology & Drugs PSDV pSivida Limited (ADR) NASD Healthcare 103.779 NA NA 4.70 1.74 NA 21.931 19.960 0.29 0.008 8.99 0.000 NA NA 6.80

Biotechnology & Drugs PMD Psychemedics Corp. AMEX Healthcare 61.747 NA NA 11.95 7.27 16.77 5.167 5.000 32.90 0.036 3.23 0.000 3.35 NA 4.40

Biotechnology & Drugs QLTI QLT Inc. (USA) NASD Healthcare 620.413 0.59 17.50 6.71 0.69 NA 92.461 91.800 52.80 -2.199 0.71 -0.006 NA 19.02 10.04

Biotechnology & Drugs QSC Questcor Pharmaceuticals AMEX Healthcare 47.064 NA NA 0.89 10.23 1,745.10 52.881 44.400 6.14 -1.314 16.04 1.129 NA 12.75 4.46

Biotechnology & Drugs REGN Regeneron Pharmaceuticals, Inc. NASD Healthcare 612.734 NA NA 10.91 4.49 NA 56.163 36.400 53.06 1.248 35.19 -7.542 NA 146.65 9.69

Biotechnology & Drugs RGN RegeneRx Biopharmaceut. AMEX Healthcare 122.278 NA NA 3.25 13.37 NA 37.624 30.400 0.75 0.032 19.20 2.154 NA NA 16.86

Biotechnology & Drugs RNVS Renovis, Inc. NASD Healthcare 458.161 NA NA 15.84 4.05 NA 28.924 22.600 60.93 3.559 21.86 -0.073 NA 3.46 10.56

Biotechnology & Drugs RGEN Repligen Corporation NASD Healthcare 88.040 NA NA 2.92 3.38 81.61 30.151 28.400 18.59 1.315 5.81 -0.050 NA NA 6.65

Biotechnology & Drugs RIGL Rigel Pharmaceuticals, Inc. NASD Healthcare 193.542 NA NA 8.01 1.86 NA 24.163 22.000 80.98 3.923 8.95 -0.327 NA 1.93 8.70

Biotechnology & Drugs SLXP Salix Pharmaceuticals Ltd NASD Healthcare 887.983 0.90 26.00 19.22 3.69 NA 46.201 43.700 79.43 -0.209 5.41 -0.010 NA 0.15 3.90

Biotechnology & Drugs LIV Samaritan Pharmaceuticals, Inc. AMEX Healthcare 57.132 NA NA 0.42 20.00 NA 136.029 127.700 0.59 0.022 6.12 0.000 NA NA 5.04

Biotechnology & Drugs SGMO Sangamo Biosciences, Inc. NASD Healthcare 97.851 NA NA 3.85 4.36 NA 25.416 10.800 34.65 0.596 57.51 0.000 NA NA 11.01

Biotechnology & Drugs SGNCE Sanguine Corporation OTC Healthcare 11.602 NA NA 0.15 36.25 5.70 80.013 39.200 NA NA 51.01 NA NA NA 9.66

Biotechnology & Drugs SNY sanofi-aventis (ADR) NYSE Healthcare 108,890.039 1.28 10.15 40.85 NA NA 2,670.283 1,900.000 6.86 1.467 28.85 0.000 1.87 NA NA

Biotechnology & Drugs SNTS Santarus, Inc. NASD Healthcare 266.825 NA 30.00 6.05 3.89 NA 44.103 39.800 46.34 8.742 9.76 0.030 NA 0.08 4.99

Biotechnology & Drugs SVNTE Savient Pharmaceuticals, Inc. NASD Healthcare 234.600 NA NA 3.86 1.57 NA 60.777 57.400 56.54 1.414 5.56 0.012 NA 0.11 2.38

Biotechnology & Drugs SCLN SciClone Pharmaceuticals NASD Healthcare 179.759 NA NA 3.92 3.41 NA 45.857 44.800 20.01 1.707 2.31 1.316 NA 10.64 4.59

Biotechnology & Drugs DDD SCOLR Pharma Inc. AMEX Healthcare 145.845 NA NA 4.17 8.34 NA 34.975 32.200 6.26 -0.055 7.93 -0.018 NA 0.07 17.65

Biotechnology & Drugs SGEN Seattle Genetics, Inc. NASD Healthcare 210.202 NA NA 4.96 2.54 NA 42.379 28.400 56.07 0.193 32.99 -0.200 NA NA 3.93

Biotechnology & Drugs STLT Select Therapeutics Inc. OTC Healthcare 0.002 NA NA 0.00 NA NA 17.560 15.000 NA NA 14.58 NA NA NA NA

Biotechnology & Drugs SNT Senesco Technologies, Inc. AMEX Healthcare 24.129 NA NA 1.56 4.32 NA 15.467 13.400 11.54 0.099 13.36 0.006 NA NA 10.19

Biotechnology & Drugs SNTKY Senetek PLC (ADR) OTC Healthcare 12.192 NA NA 0.20 NA NA 60.961 60.500 0.03 0.000 0.10 0.000 NA NA 2.33

Biotechnology & Drugs SNMX Senomyx Inc. NASD Healthcare 364.568 NA NA 12.29 10.58 NA 29.664 24.600 59.06 -0.122 17.07 -0.277 NA NA 7.00

Biotechnology & Drugs SGHL Sentigen Holding Corp. NASD Healthcare 41.110 NA NA 5.50 2.98 NA 7.475 5.100 1.38 0.000 31.77 0.000 NA 6.14 6.62

Biotechnology & Drugs SEPR Sepracor Inc. NASD Healthcare 5,861.038 0.41 92.00 55.25 NA NA 106.082 97.800 95.00 4.319 7.81 -0.589 NA NA 3.92

Biotechnology & Drugs SQNM Sequenom, Inc. NASD Healthcare 32.525 NA NA 0.81 1.74 NA 40.229 38.900 9.85 -0.513 3.30 0.000 NA 28.16 1.80

Biotechnology & Drugs SRLS SeraCare Life Sciences NASD Healthcare 301.826 1.41 20.00 22.44 3.32 34.42 13.450 11.400 42.77 0.667 15.24 -0.330 NA 22.80 4.73

Biotechnology & Drugs SERO Serologicals Corporation NASD Healthcare 711.964 1.01 17.67 20.58 1.81 40.29 34.595 34.100 NA NA 1.43 -0.236 NA 30.14 5.01

Biotechnology & Drugs SRA Serono S.A. (ADR) NYSE Healthcare 10,929.960 1.29 12.80 18.75 5.48 NA 582.931 220.000 1.34 1.666 62.26 0.000 2.00 32.74 1.68

Biotechnology & Drugs SFCC SFBC International, Inc. NASD Healthcare 288.509 0.41 24.50 15.64 0.94 10.08 18.447 17.100 89.46 1.097 7.30 0.003 NA 53.46 2.88

Biotechnology & Drugs SFPH Sheffield Pharmaceuticals OTC Healthcare 0.030 NA NA 0.25 NA NA 0.118 0.036 NA NA 69.49 NA NA NA NA

Biotechnology & Drugs SHPGY Shire plc (ADR) NASD Healthcare 6,123.743 1.49 15.04 36.95 3.54 NA 165.731 160.633 31.45 12.928 3.08 0.000 0.46 0.01 1.33

Biotechnology & Drugs SIGA SIGA Technologies, Inc. NASD Healthcare 24.911 NA NA 0.94 9.22 NA 26.501 18.000 2.80 -0.221 32.08 0.000 NA 9.46 0.52

Biotechnology & Drugs SVA Sinovac Biotech Ltd. AMEX Healthcare 217.925 NA NA 5.80 16.07 NA 37.573 18.000 2.37 0.458 52.09 0.000 NA 21.70 1.27





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 30Nov05 7 of 45 10/24/2011 3:30 PM

BioTech Industry 30Nov05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider Insider Net to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Shrs Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Purchased Yield (%) Quarterly Quarterly

Biotechnology & Drugs RNAI Sirna Therapeutics, Inc. NASD Healthcare 214.383 NA NA 3.60 4.74 NA 59.551 24.500 56.27 13.948 58.86 10.984 NA 3.69 9.31

Biotechnology & Drugs SKYE SkyePharma PLC (ADR) NASD Healthcare 575.817 NA NA 9.17 10.35 NA 62.790 51.490 0.66 -0.056 18.00 0.000 1.91 389.30 0.96

Biotechnology & Drugs SLXA Solexa, Inc. NASD Healthcare 231.040 NA NA 8.85 5.77 NA 26.106 14.100 15.77 1.817 45.99 2.918 NA 0.22 2.95

Biotechnology & Drugs SNUS Sonus Pharmaceuticals, Inc. NASD Healthcare 127.187 NA NA 4.21 5.82 NA 30.211 29.400 20.24 3.937 2.68 0.000 NA 0.26 4.27

Biotechnology & Drugs DIAGF Spectral Diagnostics, Inc (USA) OTC Healthcare 7.988 NA NA 0.40 2.53 NA 19.860 18.300 0.00 0.000 7.86 0.000 NA 250.26 2.78

Biotechnology & Drugs SPPI Spectrum Pharmaceuticals, Inc. NASD Healthcare 97.214 NA NA 4.16 1.57 NA 23.369 22.800 35.61 4.801 2.43 0.008 NA NA 12.97

Biotechnology & Drugs SLXCF Stellar Pharmaceuticals Inc. (USA) OTC Healthcare 21.055 NA NA 0.90 7.41 NA 23.266 17.700 NA NA 23.92 NA NA NA 4.89

Biotechnology & Drugs STEM StemCells, Inc. NASD Healthcare 274.999 NA NA 4.25 7.96 NA 64.706 63.400 15.31 2.085 2.02 0.000 NA 5.01 12.44

Biotechnology & Drugs STGN Stratagene Corporation NASD Healthcare 229.463 1.37 15.00 10.34 3.75 30.73 22.192 8.800 18.76 0.585 60.35 -0.266 9.67 6.57 2.00

Biotechnology & Drugs STRV Strativation Inc. OTC Healthcare 0.479 NA NA 0.07 NA NA 6.836 2.300 NA NA 66.36 NA NA NA NA

Biotechnology & Drugs SUPG SuperGen, Inc. NASD Healthcare 294.017 NA NA 5.70 4.55 NA 51.582 47.000 48.26 3.944 8.88 -0.013 NA NA 6.76

Biotechnology & Drugs SWME Swiss Medica, Inc. OTC Healthcare 13.307 NA NA 0.15 4.55 NA 88.715 75.100 0.06 0.010 15.35 0.085 NA 41.48 1.73

Biotechnology & Drugs SYMBA Symbollon Pharmaceuticals, Inc. OTC Healthcare 8.276 NA NA 1.07 6.41 NA 7.735 6.400 NA NA 17.26 NA NA NA 8.59

Biotechnology & Drugs SYNB Synbiotics Corporation OTC Healthcare 3.382 NA NA 0.10 1.64 NA 33.822 14.800 NA NA 56.24 NA NA 119.31 1.72

Biotechnology & Drugs SYBD Synthetic Blood Int'l Inc OTC Healthcare 12.966 NA NA 0.10 6.67 NA 129.660 127.100 0.02 0.000 1.97 0.000 NA NA 14.03

Biotechnology & Drugs TNOX Tanox, Inc. NASD Healthcare 754.816 NA NA 16.83 3.72 NA 44.849 25.000 58.28 1.024 44.26 -0.207 NA 2.46 12.84

Biotechnology & Drugs TPPH Tapestry Pharmaceuticals, Inc. NASD Healthcare 11.559 NA NA 0.34 0.84 NA 34.239 31.100 11.72 0.411 9.17 0.000 NA 24.33 5.17

Biotechnology & Drugs TGEN Targeted Genetics Corporation NASD Healthcare 47.955 NA NA 0.56 1.40 NA 85.634 60.100 3.88 0.034 29.82 -0.423 NA 24.53 5.01

Biotechnology & Drugs TARO Taro Pharmaceutical Industries Ltd. NASD Healthcare 398.795 0.45 30.38 13.67 1.06 19.90 29.173 26.900 77.59 3.603 7.79 0.000 NA 70.45 2.36

Biotechnology & Drugs TCPI TCPI, Inc. OTC Healthcare 0.126 NA NA 0.00 0.01 NA 96.905 91.100 0.02 0.000 5.99 0.000 NA 1.30 0.64

Biotechnology & Drugs TECH Techne Corporation NASD Healthcare 2,202.234 2.11 13.00 56.65 7.52 33.15 38.874 36.400 86.25 1.036 6.36 -0.102 NA 4.89 10.56

Biotechnology & Drugs TELK Telik, Inc. NASD Healthcare 865.694 NA 54.00 16.64 4.11 NA 52.025 51.600 95.00 3.545 0.82 0.000 NA 0.65 13.38

Biotechnology & Drugs TRCA Tercica, Inc. NASD Healthcare 303.771 NA NA 9.60 4.38 NA 31.643 16.100 40.25 2.321 49.12 -0.610 NA NA 9.93

Biotechnology & Drugs TEVA NASD

Teva Pharmaceutical Industries Ltd (ADR) Healthcare 25,056.174 0.93 22.98 41.34 4.50 26.96 606.100 557.600 66.24 49.750 8.00 0.000 0.61 34.19 2.03

Biotechnology & Drugs IMNR The Immune Response Corp. OTC Healthcare 8.581 NA NA 0.17 NA NA 52.008 29.700 3.61 0.153 42.89 9.683 NA NA 0.69

Biotechnology & Drugs MDCO The Medicines Company NASD Healthcare 950.176 1.41 33.00 19.11 5.40 485.02 49.721 44.700 95.00 1.139 10.10 -0.005 NA NA 4.91

Biotechnology & Drugs QGLY The Quigley Corporation NASD Healthcare 186.310 NA NA 15.96 8.10 82.69 11.674 9.100 4.19 0.024 22.05 0.000 NA 6.84 3.49

Biotechnology & Drugs TGX Theragenics Corporation NYSE Healthcare 100.352 NA NA 3.14 0.87 NA 31.959 31.300 34.44 -1.315 2.06 0.035 NA NA 16.89

Biotechnology & Drugs THRX Theravance, Inc. NASD Healthcare 1,328.620 NA NA 21.03 11.50 NA 63.177 44.600 31.88 1.229 29.41 0.000 NA 2.22 4.38

Biotechnology & Drugs TWTI Third Wave Technologies NASD Healthcare 120.823 NA 25.00 2.93 2.69 NA 41.236 34.900 59.25 1.302 15.36 0.058 NA 24.37 2.82

Biotechnology & Drugs THLD Threshold Pharmaceuticals, Inc. NASD Healthcare 499.426 NA NA 13.41 10.79 NA 37.243 16.800 22.90 1.415 54.89 -1.449 NA 1.21 6.24

Biotechnology & Drugs TBV Tiens Biotech Group (USA), Inc. AMEX Healthcare 342.401 NA NA 4.80 4.08 14.03 71.334 3.600 0.24 0.132 94.95 0.000 NA 12.69 7.57

Biotechnology & Drugs TTP Titan Pharmaceuticals AMEX Healthcare 47.174 NA NA 1.45 3.03 NA 32.534 30.200 18.43 -0.409 7.17 0.158 NA NA 4.46

Biotechnology & Drugs TRMS Trimeris, Inc. NASD Healthcare 242.085 NA NA 11.02 12.31 NA 21.968 19.900 93.97 1.017 9.41 0.179 NA NA 5.78

Biotechnology & Drugs TRIB Trinity Biotech plc (ADR) NASD Healthcare 115.846 NA NA 8.23 NA 21.96 14.076 12.625 10.26 0.610 10.31 0.000 NA 19.67 2.75

Biotechnology & Drugs TMGU Trinity Medical Group USA, Inc. OTC Healthcare 0.002 NA NA 0.00 NA NA 19.518 9.900 NA NA 49.28 NA NA NA 0.34

Biotechnology & Drugs TRPS Tripos, Inc. NASD Healthcare 29.538 NA NA 2.92 0.86 17.28 10.116 9.600 42.91 0.223 5.10 -0.025 NA 41.36 1.01

Biotechnology & Drugs UGNE Unigene Laboratories OTC Healthcare 283.108 NA NA 3.45 NA 2,464.29 82.060 77.000 0.38 0.006 6.20 0.000 NA NA 0.54

Biotechnology & Drugs UTHR United Therapeutics Corporation NASD Healthcare 1,682.518 0.81 35.00 72.79 7.05 42.90 23.115 22.600 95.00 -2.822 2.23 -0.220 NA 0.25 8.58

Biotechnology & Drugs UG United-Guardian, Inc. AMEX Healthcare 53.085 NA NA 10.75 3.79 20.15 4.938 2.800 7.51 -0.019 43.30 -0.001 1.67 NA 23.72

Biotechnology & Drugs VRX Valeant Pharmaceuticals International NYSE Healthcare 1,525.236 0.85 49.94 16.46 3.13 NA 92.663 92.200 95.00 3.112 0.50 0.012 1.88 161.96 3.11

Biotechnology & Drugs VLTS Valentis, Inc. NASD Healthcare 32.878 NA NA 2.20 2.82 NA 14.945 12.400 35.14 0.132 17.03 0.005 NA NA 5.11

Biotechnology & Drugs VAPH Vaso Active Pharmaceuticals, Inc. OTC Healthcare 5.164 NA NA 0.50 NA NA 10.329 5.700 1.09 0.019 44.82 0.000 NA NA 1.36

Biotechnology & Drugs VXGN VaxGen, Inc. OTC Healthcare 266.163 NA NA 8.99 8.44 NA 29.607 29.600 22.66 1.336 0.02 0.000 NA 0.01 1.47

Biotechnology & Drugs VNLS Vernalis plc (ADR) NASD Healthcare 175.172 NA NA 2.25 4.26 NA 77.850 54.500 1.03 0.042 29.99 0.000 NA 104.93 3.59

Biotechnology & Drugs VRTX Vertex Pharmaceuticals Incorporated NASD Healthcare 2,547.554 NA NA 25.70 19.07 NA 99.127 95.300 89.10 5.831 3.86 -0.240 NA 223.18 3.48

Biotechnology & Drugs VIAC Viacell, Inc. NASD Healthcare 228.584 NA 0.00 5.96 3.80 NA 38.353 27.200 24.80 3.587 29.08 -0.050 NA 3.49 4.87

Biotechnology & Drugs VICL Vical Incorporated NASD Healthcare 150.521 NA NA 5.33 1.94 NA 28.240 25.900 25.05 -0.086 8.29 0.000 NA 12.99 6.15

Biotechnology & Drugs VION Vion Pharmaceuticals, Inc. NASD Healthcare 122.069 NA NA 1.85 2.30 NA 65.983 65.300 53.07 1.894 1.03 -0.001 NA NA 11.64

Biotechnology & Drugs VQPH VioQuest Pharmaceuticals, Inc . OTC Healthcare 18.719 NA NA 1.05 12.50 NA 17.828 9.400 NA NA 47.27 NA NA NA 1.02

Biotechnology & Drugs VGNI Viragen International, Inc. OTC Healthcare 12.155 NA NA 0.17 NA NA 73.669 13.400 NA NA 81.81 NA NA NA 3.14

Biotechnology & Drugs VRA Viragen, Inc. AMEX Healthcare 21.613 NA NA 0.55 NA NA 39.297 38.400 10.38 1.633 2.28 0.050 NA NA 3.50

Biotechnology & Drugs VRAL Viral Genetics, Inc. OTC Healthcare 47.238 NA NA 0.51 14.17 NA 92.624 35.200 0.06 0.000 62.00 0.000 NA 57.69 0.11

Biotechnology & Drugs VBAC Virbac Corporation OTC Healthcare 85.104 NA NA 3.80 4.08 22.21 22.396 8.300 2.82 -0.008 62.94 0.000 NA 83.78 1.01

Biotechnology & Drugs VPHM ViroPharma Incorporated NASD Healthcare 1,038.305 0.86 19.00 17.92 11.96 17.98 57.941 55.700 61.97 11.720 3.87 0.024 NA 99.97 2.71

Biotechnology & Drugs PRH VitaCube Systems Holdings, Inc. AMEX Healthcare 14.959 NA NA 1.56 2.42 NA 9.589 5.300 NA NA 44.73 NA NA NA 16.49

Biotechnology & Drugs VTLV Vital Living, Inc. OTC Healthcare 4.230 NA NA 0.04 0.23 NA 105.754 84.600 0.78 0.000 20.00 0.000 NA 15.81 0.45

Biotechnology & Drugs VVUS VIVUS, Inc. NASD Healthcare 148.719 NA NA 3.34 5.44 NA 44.527 43.200 46.22 1.832 2.98 -0.044 NA 18.04 2.92

Biotechnology & Drugs VYRX Vyrex Corporation OTC Healthcare 0.637 NA NA 0.08 NA NA 8.493 7.300 NA NA 14.05 NA NA NA 0.14

Biotechnology & Drugs WPI Watson Pharmaceuticals, Inc. NYSE Healthcare 3,691.248 2.44 9.17 33.31 1.76 23.23 110.815 105.400 82.18 5.401 4.89 -0.205 NA 28.17 5.30

Biotechnology & Drugs WFHCQ Women First HealthCare OTC Healthcare 0.005 NA NA 0.00 NA NA 26.658 16.000 0.00 0.000 39.98 0.000 NA NA 0.16

Biotechnology & Drugs XCYT Xcyte Therapies, Inc. NASD Healthcare 7.672 NA NA 0.39 0.25 NA 19.672 14.400 16.64 0.149 26.80 0.000 NA 14.27 5.70

Biotechnology & Drugs XKEM Xechem International, Inc OTC Healthcare 7.012 NA NA 0.03 NA NA 259.689 248.200 0.19 0.000 4.42 0.000 NA NA 0.08

Biotechnology & Drugs XNPT XenoPort, Inc. NASD Healthcare 258.253 NA NA 13.08 3.34 NA 19.744 13.800 27.26 0.222 30.10 0.013 NA 2.07 8.90

Biotechnology & Drugs XOMA XOMA Limited NASD Healthcare 151.015 NA NA 1.75 NA NA 86.294 76.900 17.62 -2.590 10.89 0.005 NA NA 4.61





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BioTech Industry 30Nov05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider Insider Net to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Shrs Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Purchased Yield (%) Quarterly Quarterly

Biotechnology & Drugs XTLB XTL Biopharmaceuticals Ltd.(ADR) NASD Healthcare 136.192 NA NA 8.05 8.99 NA 16.918 16.580 0.00 0.000 2.00 0.000 NA NA 6.04

Biotechnology & Drugs YMI YM BioSciences Inc. (USA) AMEX Healthcare 124.093 NA NA 2.98 4.52 NA 41.412 40.600 12.49 -1.734 1.96 0.000 NA NA 8.14

Biotechnology & Drugs ZILA Zila, Inc. NASD Healthcare 156.499 NA 27.50 3.41 3.04 NA 45.894 45.400 25.11 0.474 1.08 0.000 NA 7.36 3.33

Biotechnology & Drugs ZONA Zonagen, Inc. NASD Healthcare 48.584 NA NA 4.82 2.53 NA 10.080 9.900 23.33 -0.642 1.79 0.000 NA NA 31.01

Biotechnology & Drugs ZMTX ZymeTx, Inc. OTC Healthcare 0.516 NA NA 0.06 NA NA 8.606 6.600 0.00 0.000 23.31 0.000 NA NA 0.20

Biotechnology & Drugs ZGEN ZymoGenetics, Inc. NASD Healthcare 1,083.536 NA 15.00 16.51 3.12 NA 65.629 32.800 34.96 6.728 50.02 -0.030 NA NA 15.25

Major Drugs ABT Abbott Laboratories NYSE Healthcare 58,372.723 1.45 9.67 37.63 4.09 17.51 1,551.228 1,541.500 62.16 -5.132 0.63 -0.049 2.92 46.15 1.25

Major Drugs ARXT Adams Respiratory Therapeutics, Inc. NASD Healthcare 1,510.872 0.98 30.00 45.37 9.21 NA 33.301 29.200 58.80 19.545 12.31 -1.447 NA NA 7.29

Major Drugs ACL Alcon, Inc. NYSE Healthcare 42,766.273 1.61 20.32 139.40 16.70 41.06 306.788 73.600 23.30 2.383 76.01 0.000 0.71 37.68 1.48

Major Drugs ALLI Allion Healthcare, Inc. NASD Healthcare 200.351 2.66 17.50 15.65 3.00 NA 12.802 4.000 45.19 2.990 68.75 0.000 NA 2.38 3.21

Major Drugs APNS Applied Neurosolutions, Inc. OTC Healthcare 32.084 NA NA 0.34 17.90 NA 94.365 86.200 5.44 0.004 8.65 -1.375 NA 0.11 3.82

Major Drugs AZN AstraZeneca PLC (ADR) NYSE Healthcare 77,084.703 1.13 12.32 46.86 5.69 17.19 1,645.000 1,628.600 9.18 10.886 1.00 0.000 1.62 9.37 1.94

Major Drugs AVRX Avalon Pharmaceuticals, Inc. NASD Healthcare 45.810 NA 25.00 5.45 NA NA 8.406 2.750 0.48 0.040 67.29 1.088 NA 300.90 0.26

Major Drugs BAY Bayer AG (ADR) NYSE Healthcare 29,680.148 2.61 5.00 40.71 2.32 16.15 730.342 723.000 4.03 0.868 1.00 0.000 1.73 84.69 1.94

Major Drugs BMY Bristol Myers Squibb Co. NYSE Healthcare 42,319.543 4.16 4.17 21.63 3.76 16.30 1,956.521 1,942.700 67.55 -3.839 0.71 -0.001 5.18 54.78 1.53

Major Drugs LLY Eli Lilly & Co. NYSE Healthcare 58,536.352 1.60 10.20 51.50 4.93 44.01 1,136.628 981.300 70.56 28.326 13.67 -2.652 2.95 57.19 2.35

Major Drugs GSK GlaxoSmithKline plc (ADR) NYSE Healthcare 147,035.688 1.89 8.43 50.47 11.62 18.42 2,913.170 2,884.050 9.51 1.182 1.00 0.000 2.82 96.17 1.50

Major Drugs JNJ Johnson & Johnson NYSE Healthcare 183,523.438 1.50 10.91 61.69 4.98 19.72 2,974.930 2,945.200 64.01 -19.256 1.00 -0.045 2.14 6.56 2.54

Major Drugs MRK Merck & Co., Inc. NYSE Healthcare 64,899.250 -3.18 -3.93 29.68 3.66 14.20 2,186.632 2,164.800 61.17 -7.787 1.00 0.000 5.12 41.16 1.65

Major Drugs NVD Novadel Pharma Inc AMEX Healthcare 52.371 NA NA 1.29 6.58 NA 40.597 29.000 5.91 -0.316 28.57 0.029 NA 0.00 3.82

Major Drugs NVS Novartis AG (ADR) NYSE Healthcare 123,906.102 1.46 11.54 53.19 3.90 33.56 2,329.500 2,300.000 9.56 20.427 1.27 0.000 1.66 21.75 1.48

Major Drugs PFE Pfizer Inc. NYSE Healthcare 157,600.453 1.32 7.95 21.38 2.35 19.38 7,371.396 7,310.800 62.05 1.076 0.82 -0.310 3.56 18.18 1.61

Major Drugs PBH Prestige Brands Holdings, Inc. NYSE Healthcare 605.495 1.15 11.60 12.10 1.53 420.87 50.041 33.000 58.07 -1.717 34.05 0.033 NA 124.85 2.67

Major Drugs RHHBY Roche Holding Ltd. (ADR) OTC Healthcare 130,746.891 1.81 14.29 75.75 5.40 26.06 1,725.125 1,382.400 0.28 0.104 19.87 0.000 NA 24.51 3.89

Major Drugs SHR Schering AG (ADR) NYSE Healthcare 12,328.373 1.31 12.10 65.00 3.25 17.61 190.000 24.700 3.38 -0.377 87.00 0.000 1.97 7.74 2.47

Major Drugs SGP Schering-Plough Corp. NYSE Healthcare 28,153.906 1.66 19.78 19.05 4.78 NA 1,477.895 1,434.700 77.12 33.704 2.92 -0.100 1.15 37.59 2.25

Major Drugs SNSS Sunesis Pharmaceuticals, Inc. NASD Healthcare 111.593 NA NA 5.20 2.58 NA 21.460 6.700 4.81 1.033 68.78 1.095 NA 5.76 5.27

Major Drugs SNTA Synta Pharmaceuticals Corp. NASD Healthcare NA NA NA NA NA NA NA NA NA NA 100.00 NA NA NA NA

Major Drugs WYE Wyeth NYSE Healthcare 55,301.082 1.50 8.80 41.20 4.88 49.89 1,342.259 1,335.100 74.50 9.581 0.53 -0.008 2.43 68.85 1.58









492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 30Nov05 9 of 45 10/24/2011 3:30 PM

BioTech Industry 30Sep05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs APPA A.P. Pharma, Inc. NASD Healthcare 43.870 NA NA 1.74 4.18 NA 25.210 24.200 37.17 -0.190 4.02 1 NA NA 4.77

Biotechnology & Drugs AAIIQ aaiPharma Inc. OTC Healthcare 18.580 NA NA 0.65 NA NA 28.590 23.000 4.26 -4.350 19.54 -1 NA NA 0.13

Biotechnology & Drugs ASTM Aastrom Biosciences, Inc. NASD Healthcare 238.470 NA NA 2.35 7.28 NA 101.480 96.300 12.09 5.060 5.10 2 NA NA 38.14

Biotechnology & Drugs ABAX Abaxis, Inc. NASD Healthcare 260.000 2.18 25.00 13.05 4.14 63.45 19.920 19.300 48.81 -0.330 3.13 2 NA 0.00 5.85

Biotechnology & Drugs ABGX Abgenix, Inc. NASD Healthcare 1,139.100 -0.32 20.00 12.68 11.22 NA 89.830 79.500 88.74 5.780 11.50 0 NA 3.06 12.10

Biotechnology & Drugs ABRXQ Able Laboratories Inc. OTC Healthcare 2.780 NA NA 0.15 0.03 0.17 18.520 17.700 34.55 -9.230 4.41 0 NA 0.00 6.81

Biotechnology & Drugs ACAD ACADIA Pharmaceuticals Inc. NASD Healthcare 266.790 NA NA 11.37 4.36 NA 23.460 17.400 33.28 2.390 25.84 2 NA 0.03 6.45

Biotechnology & Drugs ACAM Acambis plc (ADR) NASD Healthcare 459.430 NA NA 8.57 2.58 NA 53.610 46.100 2.70 -0.030 14.01 0 NA 0.07 3.00

Biotechnology & Drugs ACCL Accelrys, Inc. NASD Healthcare 176.620 NA NA 6.76 1.95 NA 26.130 25.700 54.27 -1.050 1.63 0 NA NA 1.58

Biotechnology & Drugs AKC Access Pharmaceuticals AMEX Healthcare 13.840 NA NA 0.88 NA NA 15.720 14.000 23.04 -0.410 10.96 0 NA NA 0.19

Biotechnology & Drugs AGNM Acrongenomics Inc. OTC Healthcare 92.950 NA NA 5.70 11.09 NA 16.310 12.200 0.00 0.000 25.19 0 NA 0.00 1.32

Biotechnology & Drugs ACUR Acura Pharmaceuticals, Inc. OTC Healthcare 13.200 NA NA 0.57 NA NA 23.150 19.900 0.72 0.020 14.05 0 NA NA 1.04

Biotechnology & Drugs ACUS Acusphere, Inc. NASD Healthcare 116.400 NA NA 5.44 1.60 NA 21.400 19.600 50.88 0.550 8.40 -2 NA 0.36 3.12

Biotechnology & Drugs ADZA Adeza Biomedical Corporation NASD Healthcare 293.430 1.32 33.67 17.41 3.42 32.58 16.850 11.100 64.21 6.080 34.14 -12 NA NA 13.50

Biotechnology & Drugs ADH Adherex Technologies Inc. (USA) AMEX Healthcare 40.920 NA NA 1.12 1.80 NA 36.540 30.800 NA NA 15.70 NA NA NA 4.77

Biotechnology & Drugs ADLR Adolor Corporation NASD Healthcare 417.450 -0.31 25.00 10.68 4.28 NA 39.090 37.700 78.80 2.410 3.55 0 NA NA 7.82

Biotechnology & Drugs ADLS Advanced Life Sciences Holdings, Inc. NASD Healthcare 88.600 NA NA 4.97 NA NA 17.830 17.800 NA NA 0.15 NA NA NA 0.06

Biotechnology & Drugs AVM Advanced Magnetics, Inc. AMEX Healthcare 95.780 NA NA 9.71 3.26 NA 9.860 8.600 27.25 -0.210 12.81 0 NA NA 9.26

Biotechnology & Drugs APPI Advanced Plant Pharmaceuticals Inc. OTC Healthcare 1.490 NA NA 0.00 NA NA 786.380 747.100 0.00 0.000 5.00 0 NA NA 0.03

Biotechnology & Drugs ATISZ Advanced Tissue Sciences OTC Healthcare 3.730 NA NA 0.05 0.26 NA 73.150 47.600 1.52 -0.010 34.93 0 NA 0.31 1.21

Biotechnology & Drugs ADVR Advanced Viral Research OTC Healthcare 69.650 NA NA 0.10 9.09 NA 696.490 647.700 0.05 -0.150 7.01 2 NA NA 26.31

Biotechnology & Drugs AVNC Advancis Pharmaceutical Corporation NASD Healthcare 41.880 -0.03 30.00 1.41 0.91 NA 29.700 15.300 13.33 -0.280 48.48 2 NA 0.05 3.69

Biotechnology & Drugs ANX ADVENTRX Pharmaceuticals, Inc. AMEX Healthcare 224.500 NA NA 3.40 23.94 NA 66.030 54.100 8.21 3.100 18.07 4 NA NA 7.34

Biotechnology & Drugs AOLS Aeolus Pharmaceuticals, Inc. OTC Healthcare 15.700 NA NA 1.12 26.05 NA 14.020 5.600 5.72 0.000 60.05 36 NA 1.39 2.12

Biotechnology & Drugs AEZS AEterna Zentaris Inc. (USA) NASD Healthcare 221.470 NA NA 4.80 1.89 21.69 46.140 42.400 13.01 4.840 8.11 0 NA 0.44 1.73

Biotechnology & Drugs AEMD Aethlon Medical, Inc. OTC Healthcare 4.150 NA NA 0.22 NA NA 18.890 16.500 NA NA 12.63 NA NA NA 0.01

Biotechnology & Drugs AFFX Affymetrix, Inc. NASD Healthcare 2,951.290 1.88 26.00 46.23 9.10 46.58 63.840 63.600 95.00 0.750 0.37 -23 NA 0.37 4.48

Biotechnology & Drugs AKES Akesis Pharmaceuticals Inc OTC Healthcare 112.440 NA NA 7.50 250.00 NA 14.990 6.100 NA NA 59.31 NA NA NA 5.09

Biotechnology & Drugs AKN Akorn, Inc. AMEX Healthcare 88.900 NA NA 3.40 12.41 NA 26.150 10.500 24.88 0.710 59.84 0 NA 0.18 2.24

Biotechnology & Drugs AMRI Albany Molecular Research NASD Healthcare 394.000 1.38 15.00 12.18 1.27 20.31 32.350 27.400 58.12 0.720 15.30 2 NA 0.16 7.91

Biotechnology & Drugs ALXN Alexion Pharmaceuticals, Inc. NASD Healthcare 777.380 NA NA 27.65 7.88 NA 28.110 27.200 95.00 -0.300 3.25 -8 NA 1.53 8.80

Biotechnology & Drugs ACEL Alfacell Corporation NASD Healthcare 69.270 NA NA 1.90 14.39 NA 36.460 35.800 14.72 0.120 1.80 0 NA 0.04 3.68

Biotechnology & Drugs ALKS Alkermes, Inc. NASD Healthcare 1,521.320 -9.22 5.50 16.80 NA NA 90.550 87.600 94.82 3.380 3.26 -3 NA NA 3.78

Biotechnology & Drugs AGN Allergan, Inc. NYSE Healthcare 11,982.460 1.69 16.79 91.62 10.56 38.22 130.780 128.200 95.00 8.570 1.98 0 0.44 0.51 2.61

Biotechnology & Drugs ALLP Alliance Pharmaceutical Corp. OTC Healthcare 3.750 NA NA 0.11 NA NA 34.120 31.700 3.24 0.780 7.09 0 NA NA 0.50

Biotechnology & Drugs ALTH Allos Therapeutics, Inc. NASD Healthcare 134.240 NA NA 2.44 2.12 NA 55.020 52.800 22.15 1.810 4.03 4 NA NA 26.15

Biotechnology & Drugs ALNY Alnylam Pharmaceuticals, Inc. NASD Healthcare 239.570 NA NA 11.30 8.04 NA 21.200 8.100 9.10 -0.100 61.79 0 NA 0.27 3.75

Biotechnology & Drugs ALO Alpharma Inc. NYSE Healthcare 1,325.160 0.72 33.50 24.87 1.58 NA 53.280 40.700 78.51 -2.600 23.62 0 0.72 0.64 1.06

Biotechnology & Drugs AAA Altana AG(ADR) NYSE Healthcare 7,620.600 NA NA 56.33 3.50 15.21 135.290 67.600 4.32 3.750 50.03 0 2.16 0.04 NA

Biotechnology & Drugs ALT Alteon Inc. AMEX Healthcare 17.400 NA NA 0.30 1.65 NA 58.000 53.400 15.99 -0.760 7.93 0 NA NA 6.14

Biotechnology & Drugs AMAR Amarillo Biosciences, Inc OTC Healthcare 4.400 NA NA 0.27 NA NA 16.300 12.100 0.10 0.020 25.76 -1 NA NA 0.01

Biotechnology & Drugs AMRN Amarin Corporation plc (ADR) NASD Healthcare 55.900 NA NA 1.48 1.47 NA 37.770 15.500 0.10 0.020 58.96 0 NA NA 5.07

Biotechnology & Drugs MABAA American Biogenetic Sciences, Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 44.950 34.500 NA NA 23.25 NA NA NA 0.06

Biotechnology & Drugs AOB American Oriental Bioengineering, Inc. AMEX Healthcare 182.470 NA NA 4.55 4.80 16.53 40.100 13.600 NA NA 66.09 NA NA 0.13 2.74

Biotechnology & Drugs APPX American Pharmaceutical Partners, Inc. NASD Healthcare 3,297.040 1.29 27.77 45.66 8.78 41.77 72.210 20.800 28.27 0.270 71.19 1 NA NA 4.11

Biotechnology & Drugs ABC AmerisourceBergen Corp. NYSE Healthcare 8,023.490 1.91 12.25 77.30 1.91 23.45 103.800 102.700 95.00 2.290 1.06 -5 0.13 0.21 1.28

Biotechnology & Drugs AMGN Amgen, Inc. NASD Healthcare 98,297.380 1.44 17.38 79.67 5.01 36.31 1,233.810 1,225.500 70.05 21.750 0.67 -18 NA 0.20 1.63

Biotechnology & Drugs AMLN Amylin Pharmaceuticals NASD Healthcare 3,635.030 NA NA 34.79 93.27 NA 104.480 99.400 95.00 19.820 4.87 -17 NA 9.86 8.94

Biotechnology & Drugs ANDS Anadys Pharmaceuticals, Inc. NASD Healthcare 302.150 NA NA 10.67 13.39 NA 28.320 24.400 30.36 1.480 13.84 -8 NA 0.25 3.44

Biotechnology & Drugs ADRX Andrx Corporation NASD Healthcare 1,130.710 1.27 17.23 15.43 1.51 14.94 73.280 71.600 83.74 1.660 2.29 0 NA NA 3.51

Biotechnology & Drugs ANPI Angiotech Pharmaceuticals, Inc. (USA) NASD Healthcare 1,179.420 0.78 20.00 14.02 2.42 11.84 84.120 83.300 49.37 -0.010 0.98 0 NA NA 8.09

Biotechnology & Drugs ANIK Anika Therapeutics, Inc. NASD Healthcare 123.900 NA NA 11.82 3.59 26.05 10.480 9.700 47.03 0.930 7.47 -11 NA NA 9.93

Biotechnology & Drugs ANXB Antex Biologics, Inc. OTC Healthcare 0.010 NA NA 0.00 NA NA 12.410 10.300 NA NA 16.99 NA NA NA 0.79

Biotechnology & Drugs AGEN Antigenics, Inc. NASD Healthcare 247.110 NA 0.00 5.42 3.69 NA 45.590 24.300 17.24 0.220 46.70 0 NA 0.85 4.92

Biotechnology & Drugs APHT Aphton Corporation NASD Healthcare 37.620 NA NA 0.63 NA NA 59.720 58.000 29.68 -1.450 2.88 0 NA NA 1.25

Biotechnology & Drugs ARNA Arena Pharmaceuticals NASD Healthcare 349.680 NA NA 9.90 2.61 NA 35.320 32.400 79.66 3.740 8.27 2 NA NA 2.98

Biotechnology & Drugs AGNT Argonaut Technologies, Inc OTC Healthcare 6.420 NA NA 0.31 0.20 NA 20.770 20.300 30.16 -0.620 2.28 -24 NA 0.00 5.64

Biotechnology & Drugs ARIA Ariad Pharmaceuticals, Inc. NASD Healthcare 393.640 -0.77 10.00 7.43 9.39 NA 52.980 49.100 48.22 4.480 7.32 0 NA 0.21 3.84

Biotechnology & Drugs ARQL ArQule, Inc. NASD Healthcare 275.380 NA NA 7.83 2.53 NA 35.170 34.400 52.58 1.720 2.19 2 NA 0.01 7.29

Biotechnology & Drugs ARRY Array BioPharma Inc. NASD Healthcare 276.380 -0.18 37.50 7.18 2.78 NA 38.490 33.200 72.84 0.390 13.75 -2 NA 0.10 5.99

Biotechnology & Drugs ASPV Aspreva Pharmaceuticals Corporation NASD Healthcare 485.240 29.71 16.00 14.26 4.39 NA 34.030 7.200 23.68 5.490 78.84 0 NA 0.01 10.65

Biotechnology & Drugs ASTR Astralis, Ltd. OTC Healthcare 13.720 NA NA 0.15 NA NA 91.450 24.000 0.00 -0.600 73.76 0 NA NA 0.61

Biotechnology & Drugs AGIX AtheroGenics, Inc. NASD Healthcare 605.440 -0.28 25.00 16.03 NA NA 37.770 36.300 95.00 1.440 3.89 13 NA NA 22.23

Biotechnology & Drugs AIMM AutoImmune Inc. OTC Healthcare 15.400 NA NA 0.91 1.61 NA 16.920 16.800 28.29 -0.360 0.71 0 NA NA 80.02

Biotechnology & Drugs AUXL Auxilium Pharmaceuticals, Inc. NASD Healthcare 145.180 -0.11 30.00 4.98 2.89 NA 29.150 20.700 63.74 2.570 28.99 6 NA 0.13 4.43







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Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs AVN AVANIR Pharmaceuticals AMEX Healthcare 334.830 NA NA 3.09 32.19 NA 108.360 98.400 35.87 6.710 9.19 1 NA 0.10 2.36

Biotechnology & Drugs AVAN AVANT Immunotherapeutics, Inc. NASD Healthcare 96.380 NA NA 1.30 3.32 NA 74.140 73.700 19.76 1.120 0.59 0 NA 0.07 9.25

Biotechnology & Drugs AVXT AVAX Technologies, Inc. OTC Healthcare 19.390 NA NA 0.31 2.56 NA 62.550 61.300 3.63 -0.050 1.99 0 NA 0.05 3.38

Biotechnology & Drugs AVII AVI BioPharma, Inc. NASD Healthcare 116.650 NA NA 2.64 3.02 NA 44.180 37.700 6.94 -1.440 14.68 1 NA NA 16.84

Biotechnology & Drugs AVGN Avigen, Inc. NASD Healthcare 58.100 NA NA 2.78 0.87 NA 20.900 20.800 40.73 -0.520 0.48 0 NA 0.12 32.97

Biotechnology & Drugs AXCA Axcan Pharma Inc. (USA) NASD Healthcare 590.180 1.74 15.00 12.92 1.45 20.81 45.680 42.000 49.01 3.070 8.06 0 NA 0.31 3.08

Biotechnology & Drugs AXJ AXM Pharma, Inc. AMEX Healthcare 25.430 NA NA 1.30 2.93 NA 19.560 11.400 3.06 -0.410 41.73 0 NA 0.42 0.99

Biotechnology & Drugs AXYX Axonyx Inc. NASD Healthcare 61.720 NA NA 1.15 0.91 NA 53.670 51.900 21.69 -1.830 3.29 4 NA 0.00 8.37

Biotechnology & Drugs BRL Barr Pharmaceuticals, Inc. NYSE Healthcare 5,855.750 1.12 15.65 54.92 4.60 27.08 106.620 98.400 74.78 1.590 7.71 -23 NA 0.02 4.66

Biotechnology & Drugs BTRX Barrier Therapeutics, Inc. NASD Healthcare 202.060 -0.17 22.50 8.39 2.05 15.81 24.080 14.900 59.79 -1.410 38.13 0 NA 0.01 12.51

Biotechnology & Drugs BGCC Beluga Composites Corp. OTC Healthcare 0.050 NA NA 1.46 NA NA 0.030 0.010 NA NA 77.14 NA NA 0.02 2.46

Biotechnology & Drugs BNT Bentley Pharmaceuticals, Inc. NYSE Healthcare 258.110 0.89 32.00 11.95 2.98 32.92 21.600 19.300 38.64 -0.120 10.64 1 NA 0.03 2.49

Biotechnology & Drugs BASI Bioanalytical Systems, Inc. NASD Healthcare 26.450 NA NA 5.43 1.35 NA 4.870 3.200 14.60 0.080 34.31 0 NA 0.78 1.49

Biotechnology & Drugs BCRX BioCryst Pharmaceuticals, Inc. NASD Healthcare 255.830 NA NA 9.78 6.26 NA 26.160 16.500 36.69 -0.170 36.92 -1 NA NA 14.95

Biotechnology & Drugs BDSI BioDelivery Sciences International, Inc. NASD Healthcare 13.080 NA NA 1.80 NA NA 7.270 1.600 1.06 0.010 77.99 0 NA 0.58 0.66

Biotechnology & Drugs BIVN Bioenvision, Inc. NASD Healthcare 325.690 -1.87 10.00 8.03 4.03 NA 40.560 40.500 43.38 0.770 0.15 -2 NA NA 14.03

Biotechnology & Drugs BIIB Biogen Idec Inc NASD Healthcare 13,357.540 1.69 14.39 39.48 1.98 95.63 338.340 337.200 76.69 0.600 0.34 -3 NA 0.01 3.32

Biotechnology & Drugs BMRN BioMarin Pharmaceutical NASD Healthcare 643.250 NA NA 8.73 NA NA 73.680 71.800 66.43 3.610 2.56 1 NA NA 0.90

Biotechnology & Drugs BIOM Biomira Inc. (USA) NASD Healthcare 108.770 NA NA 1.38 4.31 NA 78.820 78.000 2.45 -1.390 1.04 0 NA NA 13.67

Biotechnology & Drugs BNTK Bionet Technologies, Inc. OTC Healthcare 0.000 NA NA 0.00 0.01 NA 13.810 8.700 NA NA 37.02 NA NA NA 0.90

Biotechnology & Drugs BNRX Bionutrics, Inc. OTC Healthcare 41.280 NA NA 1.84 3.53 NA 22.440 6.400 NA NA 71.48 NA NA 0.12 0.12

Biotechnology & Drugs BPRG BioProgress PLC (USA) NASD Healthcare 53.400 NA NA 4.72 1.11 NA 11.310 10.750 0.20 0.000 4.99 0 NA NA 2.83

Biotechnology & Drugs BIOP BioPulse International OTC Healthcare 0.020 NA NA 0.00 NA NA 15.450 7.600 NA NA 50.81 NA NA NA 0.04

Biotechnology & Drugs BPUR Biopure Corporation NASD Healthcare 27.040 NA NA 1.11 0.60 NA 24.360 23.100 1.93 0.470 5.17 1 NA NA 4.43

Biotechnology & Drugs BPA BioSante Pharmaceuticals, Inc. AMEX Healthcare 64.990 NA NA 3.35 5.94 NA 19.400 16.900 26.72 -0.180 12.88 -11 NA NA 7.90

Biotechnology & Drugs BSTE Biosite Incorporated NASD Healthcare 1,067.370 1.37 15.57 61.86 3.86 22.10 17.250 15.700 93.09 -0.410 9.01 -15 NA 0.07 4.34

Biotechnology & Drugs BSOU Bio-Solutions International, Inc. OTC Healthcare 4.430 NA NA 8.50 NA NA 0.520 0.020 NA NA 96.16 NA NA NA 0.08

Biotechnology & Drugs BIOI BioSource International, Inc. NASD Healthcare 124.150 NA NA 12.59 3.06 288.76 9.860 8.300 26.32 -0.770 15.83 0 NA NA 3.50

Biotechnology & Drugs BSTC BioSpecifics Technologies Corp. OTC Healthcare 7.460 NA NA 1.40 3.87 NA 5.330 3.000 2.69 0.000 43.67 0 NA 1.03 0.65

Biotechnology & Drugs BIOHF Biotech Holdings Ltd. (USA) OTC Healthcare 19.460 NA NA 0.21 NA NA 92.230 45.200 0.00 0.000 50.99 0 NA NA 0.47

Biotechnology & Drugs BTIM BioTime, Inc. OTC Healthcare 7.680 NA NA 0.43 NA NA 17.870 17.200 1.70 0.010 3.76 2 NA NA 2.63

Biotechnology & Drugs BTRNQ BioTransplant Inc. OTC Healthcare 0.630 NA NA 0.03 0.04 NA 25.390 19.600 0.00 -0.010 22.79 0 NA 0.04 2.39

Biotechnology & Drugs BVF Biovail Corporation (USA) NYSE Healthcare 3,725.300 0.84 16.09 23.37 3.51 33.71 159.410 124.300 34.52 -3.850 22.02 0 NA 0.42 2.05

Biotechnology & Drugs BLSI Boston Life Sciences, Inc. NASD Healthcare 21.990 NA NA 2.11 11.92 NA 10.420 8.600 4.76 0.070 17.48 0 NA NA 1.65

Biotechnology & Drugs BDY Bradley Pharmaceuticals, Inc. NYSE Healthcare 172.940 0.33 20.00 10.92 1.07 8.97 15.840 13.900 61.42 -1.480 12.23 0 NA 0.67 3.27

Biotechnology & Drugs KDUS Cadus Corporation OTC Healthcare 21.290 NA NA 1.62 0.84 NA 13.140 7.500 7.38 0.720 42.94 3 NA NA 697.94

Biotechnology & Drugs KAL Callisto Pharmaceuticals, Inc. AMEX Healthcare 40.920 NA NA 1.31 14.56 NA 31.240 25.500 6.99 0.560 18.37 6 NA NA 2.61

Biotechnology & Drugs CBM Cambrex Corporation NYSE Healthcare 500.710 2.15 11.67 18.96 1.36 NA 26.410 25.400 87.58 -0.240 3.82 -7 0.63 0.55 2.83

Biotechnology & Drugs CATG Cambridge Antibody Tech. Group plc (ADR) NASD Healthcare 676.730 NA NA 13.11 2.74 NA 51.620 32.100 3.78 0.010 37.81 0 NA NA 4.38

Biotechnology & Drugs CNVX CancerVax Corporation NASD Healthcare 95.900 NA NA 3.44 1.64 NA 27.880 17.300 22.56 -0.830 37.94 0 NA 0.25 3.90

Biotechnology & Drugs CPD A

Caraco Pharmaceutical Laboratories Ltd. MEX Healthcare 229.340 0.33 33.00 8.69 NA NA 26.390 9.500 12.06 0.260 64.00 0 NA NA 2.83

Biotechnology & Drugs CAH Cardinal Health, Inc. NYSE Healthcare 27,078.440 1.43 13.05 63.44 3.15 26.42 426.840 421.200 82.86 -1.440 1.32 -14 0.38 0.31 1.33

Biotechnology & Drugs CRME Cardiome Pharma Corp.(USA) NASD Healthcare 447.110 NA NA 8.79 5.20 NA 50.870 49.800 35.89 3.290 2.09 0 NA 0.01 5.80

Biotechnology & Drugs CVBT Cardiovascular Biotherapeutics, Inc. OTC Healthcare 1,078.290 NA NA 8.80 77.88 NA 122.530 22.100 0.00 0.000 81.96 2 NA 0.00 30.82

Biotechnology & Drugs CARN Carrington Laboratories, Inc. NASD Healthcare 45.280 NA NA 4.21 3.36 156.91 10.760 9.500 8.65 -0.540 11.68 -1 NA 0.25 1.29

Biotechnology & Drugs CRA Celera Genomics, Applera Corp NYSE Healthcare 903.350 NA 0.00 12.13 1.10 NA 74.470 73.400 79.56 1.430 1.44 0 NA NA 16.42

Biotechnology & Drugs CELG Celgene Corporation NASD Healthcare 9,119.770 2.30 42.06 54.32 16.25 159.44 167.890 164.000 81.67 -2.820 2.32 -3 NA 0.71 8.14

Biotechnology & Drugs CEGE Cell Genesys, Inc. NASD Healthcare 248.650 NA NA 5.48 2.65 NA 45.370 45.000 63.41 -0.440 0.82 6 NA 2.09 2.65

Biotechnology & Drugs CTIC Cell Therapeutics, Inc. NASD Healthcare 187.260 NA 0.00 2.86 NA NA 65.480 62.900 22.39 -8.600 3.93 -6 NA NA 0.94

Biotechnology & Drugs CLGY Cellegy Pharmaceuticals, Inc. NASD Healthcare 42.660 NA NA 1.43 NA NA 29.830 23.900 13.00 0.710 19.89 5 NA NA 1.84

Biotechnology & Drugs CVM CEL-SCI Corporation AMEX Healthcare 34.880 NA NA 0.47 14.69 NA 74.220 6.730 1.41 0.120 90.93 -4 NA 0.00 7.39

Biotechnology & Drugs CEPH Cephalon, Inc. NASD Healthcare 2,695.250 0.94 17.85 46.42 4.80 NA 58.060 57.500 NA NA 0.97 -4 NA 3.73 6.52

Biotechnology & Drugs CERS Cerus Corporation NASD Healthcare 198.020 NA NA 8.86 4.91 27.22 22.350 21.600 34.76 0.350 3.36 0 NA 0.12 4.10

Biotechnology & Drugs CHTL Chantal Pharmaceutical OTC Healthcare 0.000 NA NA 0.00 0.00 NA 40.810 31.400 NA NA 23.06 NA NA 0.62 0.26

Biotechnology & Drugs CHTT Chattem Inc. NASD Healthcare 702.330 1.60 10.60 35.50 NA 36.43 19.780 18.300 68.91 -0.280 7.50 -24 NA NA NA

Biotechnology & Drugs CXSP ChemGenex Pharmaceuticals Limited (ADR) NASD Healthcare 72.900 NA NA 6.35 NA NA 11.480 6.770 NA NA 41.03 NA NA NA NA

Biotechnology & Drugs CHIR Chiron Corporation NASD Healthcare 8,200.950 1.92 18.60 43.65 3.31 NA 187.880 108.500 50.63 11.510 42.25 0 NA 0.44 3.15

Biotechnology & Drugs CLRI Clearant Inc OTC Healthcare 146.900 NA NA 4.10 32.54 NA 35.830 24.200 0.00 0.000 32.46 -2 NA 0.02 1.74

Biotechnology & Drugs CNXS CNS, Inc. NASD Healthcare 366.130 1.57 15.33 26.07 5.34 24.01 14.040 12.200 61.20 0.280 13.13 -24 0.92 NA 5.44

Biotechnology & Drugs CLSCE Cobalis Corporation OTC Healthcare 13.930 NA NA 0.55 NA NA 25.320 9.100 0.00 0.000 64.06 0 NA NA 0.08

Biotechnology & Drugs COLY Coley Pharmaceutical Group, Inc. NASD Healthcare 451.370 NA NA 18.20 NA NA 24.800 24.800 NA NA 0.00 NA NA 1.18 1.51

Biotechnology & Drugs CGPI CollaGenex Pharmaceutical, Inc NASD Healthcare 143.210 NA NA 9.92 4.24 NA 14.440 14.200 52.25 -0.110 1.64 2 NA NA 3.77

Biotechnology & Drugs CBRX Columbia Laboratories NASD Healthcare 156.990 NA NA 3.76 NA NA 41.750 40.800 41.11 0.210 2.28 1 NA NA 3.00

Biotechnology & Drugs CBTE Commonwealth Biotechnologies, Inc. NASD Healthcare 14.220 NA NA 4.44 2.49 NA 3.200 2.900 10.36 0.020 9.49 -1 NA 0.84 4.10

Biotechnology & Drugs COGE Compare Generiks, Inc. OTC Healthcare 0.000 NA NA 0.00 0.00 0.00 4.910 3.800 NA NA 22.69 NA NA NA 1.34





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 30Sep05 11 of 45 10/24/2011 3:30 PM

BioTech Industry 30Sep05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs CGEN Compugen Ltd. (USA) NASD Healthcare 91.770 NA NA 3.31 2.16 NA 27.730 18.300 29.09 0.110 34.00 0 NA NA 9.09

Biotechnology & Drugs CNCT Connetics Corporation NASD Healthcare 591.390 0.86 30.29 16.91 5.85 48.48 34.970 34.600 95.00 -2.390 1.07 -29 NA 2.87 6.19

Biotechnology & Drugs VEGF Corautus Genetics Inc. NASD Healthcare 77.880 NA NA 4.45 5.30 NA 17.500 14.500 16.34 -0.340 17.15 0 NA 1.28 7.70

Biotechnology & Drugs CORT Corcept Therapeutics Incorporated NASD Healthcare 113.520 NA NA 5.00 3.10 NA 22.700 9.100 22.00 -0.210 59.92 -22 NA 0.00 22.39

Biotechnology & Drugs CONX Corgenix Medical Corporation OTC Healthcare 4.050 NA NA 0.65 4.96 NA 6.230 4.700 0.00 0.000 24.52 3 NA 1.15 1.31

Biotechnology & Drugs CGTK Corgentech, Inc. NASD Healthcare 66.130 NA NA 2.36 0.74 NA 28.020 17.400 38.01 0.770 37.90 0 NA 0.00 7.82

Biotechnology & Drugs COR Cortex Pharmaceuticals AMEX Healthcare 77.650 NA NA 2.37 3.65 NA 32.760 32.400 4.95 -0.380 1.11 1 NA NA 11.84

Biotechnology & Drugs CTRX Cotherix, Inc NASD Healthcare 334.510 -0.30 30.00 13.95 5.22 NA 23.980 13.600 20.96 -1.040 43.28 0 NA NA 10.40

Biotechnology & Drugs CVGR Covalent Group, Inc. NASD Healthcare 34.830 NA NA 2.58 4.82 NA 13.500 10.600 34.66 0.810 21.49 0 NA 0.01 2.56

Biotechnology & Drugs CVD Covance Inc. NYSE Healthcare 2,990.600 1.31 19.13 47.99 4.53 27.75 62.320 61.900 84.27 -1.560 0.67 -6 NA NA 2.42

Biotechnology & Drugs CRTX Critical Therapeutics, Inc. NASD Healthcare 320.720 NA NA 9.42 3.23 NA 34.050 16.700 21.87 3.340 50.95 14 NA 0.02 8.25

Biotechnology & Drugs CRXL Crucell N.V. (ADR) NASD Healthcare 988.570 NA NA 26.81 6.37 NA 36.870 32.400 15.45 0.730 12.13 0 NA 0.01 9.39

Biotechnology & Drugs CBST Cubist Pharmaceuticals NASD Healthcare 1,154.100 -1.13 30.00 21.54 48.73 NA 53.580 53.500 95.00 4.510 0.15 -1 NA 7.00 4.63

Biotechnology & Drugs CRGN CuraGen Corporation NASD Healthcare 253.580 NA NA 4.95 3.49 NA 51.230 43.700 69.19 1.300 14.69 0 NA 3.11 11.79

Biotechnology & Drugs CRIS Curis, Inc. NASD Healthcare 221.190 NA NA 4.59 5.14 NA 48.190 47.100 37.44 1.190 2.26 -12 NA 0.11 4.65

Biotechnology & Drugs CVTX CV Therapeutics, Inc. NASD Healthcare 1,191.040 NA NA 26.75 88.58 NA 44.520 43.700 95.00 12.480 1.85 -2 NA 30.27 6.79

Biotechnology & Drugs CYAN Cyanotech Corporation NASD Healthcare 20.060 NA NA 0.96 1.32 38.37 20.900 16.800 11.50 0.010 19.60 0 NA 0.13 4.77

Biotechnology & Drugs CYPB Cypress Bioscience, Inc. NASD Healthcare 170.910 NA NA 5.41 1.85 NA 31.590 29.400 73.13 0.970 6.94 -4 NA 0.00 23.44

Biotechnology & Drugs CYTO Cytogen Corporation NASD Healthcare 69.310 NA NA 4.04 2.37 NA 17.160 17.100 39.60 -1.430 0.33 0 NA 0.09 2.96

Biotechnology & Drugs CYTK Cytokinetics, Inc. NASD Healthcare 233.020 NA NA 8.14 2.65 NA 28.630 17.900 41.18 2.930 37.47 0 NA 0.11 8.81

Biotechnology & Drugs GTF Cytomedix, Inc. AMEX Healthcare 62.330 NA NA 2.45 8.51 NA 25.440 21.000 4.98 0.980 17.46 5 NA NA 3.26

Biotechnology & Drugs CYTR CytRx Corporation NASD Healthcare 55.810 NA NA 0.97 3.06 NA 57.540 53.500 9.70 -1.380 7.02 0 NA NA 8.20

Biotechnology & Drugs DATA DATATRAK International, Inc. NASD Healthcare 115.170 NA NA 11.21 9.87 74.66 10.270 9.750 40.60 0.020 5.10 -4 NA NA 6.40

Biotechnology & Drugs DCGN deCODE genetics, Inc. NASD Healthcare 457.980 NA NA 8.39 20.77 NA 54.590 47.900 39.87 0.890 12.25 -1 NA 7.19 7.18

Biotechnology & Drugs DGENQ Deltagen, Inc. OTC Healthcare 9.320 NA NA 0.24 0.69 NA 38.850 14.000 15.91 0.000 63.97 0 NA 0.37 0.23

Biotechnology & Drugs DNDN Dendreon Corporation NASD Healthcare 398.190 NA 0.00 6.71 2.43 NA 59.340 58.700 41.03 -1.760 1.08 1 NA 0.03 10.30

Biotechnology & Drugs DEPO DepoMed, Inc. NASD Healthcare 257.880 -0.48 30.00 6.48 58.91 NA 39.800 29.400 61.36 -0.790 26.13 -1 NA 0.00 3.71

Biotechnology & Drugs DSCI Derma Sciences, Inc. OTC Healthcare 8.840 NA NA 0.72 1.16 NA 12.280 3.900 0.21 0.000 68.25 0 NA 0.19 2.04

Biotechnology & Drugs DIGE Digene Corporation NASD Healthcare 573.290 1.67 30.00 28.50 7.19 NA 20.120 15.300 88.98 1.090 23.94 -16 NA 0.01 3.06

Biotechnology & Drugs DSCO Discovery Laboratories NASD Healthcare 346.850 NA NA 6.45 11.46 NA 53.780 46.800 41.32 1.850 12.97 -5 NA 0.37 5.68

Biotechnology & Drugs DPII Discovery Partners Int'l NASD Healthcare 84.430 NA NA 3.22 0.81 NA 26.220 25.500 76.45 -2.620 2.75 0 NA 0.00 13.03

Biotechnology & Drugs DVSA Diversa Corporation NASD Healthcare 258.160 NA NA 5.79 1.99 NA 44.590 26.400 44.86 0.300 40.79 -1 NA 0.12 3.68

Biotechnology & Drugs DOCP DocPlanet.com Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 7.600 4.100 0.03 0.000 46.02 0 NA NA 0.38

Biotechnology & Drugs DOR DOR BioPharma, Inc. AMEX Healthcare 16.700 NA NA 0.33 3.59 NA 50.610 48.300 7.72 0.840 4.57 0 NA 0.03 3.33

Biotechnology & Drugs DOVP DOV Pharmaceutical, Inc. NASD Healthcare 391.220 NA NA 16.98 30.99 NA 23.040 21.200 88.82 2.440 7.99 -7 NA 6.37 6.85

Biotechnology & Drugs RDY Dr Reddy's Laboratories Limited (ADR) NYSE Healthcare 1,489.140 3.02 15.00 19.46 3.07 170.22 76.540 56.600 17.96 0.420 26.05 0 0.59 0.19 2.28

Biotechnology & Drugs DRUG Dragon Pharmaceuticals Inc. (USA) OTC Healthcare 46.530 NA NA 0.74 1.45 NA 62.880 19.200 0.00 0.000 69.46 0 NA 1.33 1.02

Biotechnology & Drugs DRAX DRAXIS Health Inc. (USA) NASD Healthcare 192.190 NA NA 4.62 2.54 19.39 41.600 34.100 40.50 0.170 18.03 0 NA NA 3.39

Biotechnology & Drugs DRRX DURECT Corporation NASD Healthcare 358.310 NA NA 6.85 34.95 NA 52.310 37.600 45.65 0.680 28.12 5 NA 6.05 7.32

Biotechnology & Drugs DUSA DUSA Pharmaceuticals, Inc NASD Healthcare 179.390 -0.14 67.10 10.60 4.14 NA 16.920 15.800 64.22 0.670 6.64 0 NA 0.00 12.08

Biotechnology & Drugs DIL Dyadic International, Inc. AMEX Healthcare 56.380 NA NA 2.50 2.78 NA 22.550 15.300 5.17 0.500 32.15 -1 NA 0.18 7.35

Biotechnology & Drugs DYAX Dyax Corp. NASD Healthcare 212.140 NA NA 5.59 3.83 NA 37.950 35.600 51.73 3.000 6.19 0 NA 0.21 4.36

Biotechnology & Drugs DVAX Dynavax Technologies Corporation NASD Healthcare 165.810 NA NA 6.70 2.90 NA 24.750 20.300 35.85 -0.250 17.97 -2 NA NA 9.90

Biotechnology & Drugs EW Edwards Lifesciences Corp NYSE Healthcare 2,655.760 1.68 13.55 44.41 4.01 33.30 59.800 56.800 95.00 3.770 5.02 -10 NA 0.41 2.30

Biotechnology & Drugs ESALY Eisai Co., Ltd (ADR) OTC Healthcare 12,207.220 3.16 7.10 42.70 3.01 25.43 285.790 211.500 0.37 0.150 26.00 0 NA 0.00 2.44

Biotechnology & Drugs ELN Elan Corporation, plc (ADR) NYSE Healthcare 3,500.540 -0.34 26.30 8.86 24.34 NA 395.100 387.200 28.71 2.810 2.00 0 NA 13.65 3.75

Biotechnology & Drugs ELI Elite Pharmaceuticals, Inc. AMEX Healthcare 54.070 NA NA 2.98 11.42 NA 18.140 18.000 15.74 -0.820 0.79 2 NA 0.56 3.77

Biotechnology & Drugs EMBX Embrex, Inc. NASD Healthcare 90.680 NA NA 11.25 1.81 28.59 8.060 7.200 40.63 -0.160 10.67 -2 NA 0.18 2.83

Biotechnology & Drugs EMIS Emisphere Technologies Inc. NASD Healthcare 104.990 NA NA 4.50 35.71 NA 23.330 22.900 35.03 -0.230 1.84 0 NA 3.76 1.38

Biotechnology & Drugs ENCY Encysive Pharmaceuticals, Inc. NASD Healthcare 685.850 -0.68 12.50 11.78 26.47 NA 58.220 57.300 91.50 3.150 1.58 -7 NA 5.03 8.22

Biotechnology & Drugs ENDP Endo Pharmaceuticals NASD Healthcare 3,525.930 0.76 20.64 26.67 4.87 26.53 132.210 68.900 54.55 -0.630 47.88 0 NA NA 2.31

Biotechnology & Drugs EVSC Endovasc, Inc. OTC Healthcare 3.490 NA NA 0.03 15.00 NA 116.460 109.100 0.06 0.020 6.32 0 NA 0.76 0.09

Biotechnology & Drugs ENMD EntreMed, Inc. NASD Healthcare 119.070 NA NA 2.39 3.67 NA 49.820 31.700 12.63 -1.670 36.37 1 NA NA 13.27

Biotechnology & Drugs ETOP Entropin, Inc. OTC Healthcare 0.920 NA NA 0.03 NA NA 30.650 23.300 0.01 0.000 23.97 0 NA NA 18.60

Biotechnology & Drugs ENZN Enzon Pharmaceuticals, Inc. NASD Healthcare 289.470 5.08 39.00 6.60 1.01 NA 43.860 43.800 77.68 0.920 0.14 1 NA 1.40 6.85

Biotechnology & Drugs EPIX EPIX Pharmaceuticals, Inc. NASD Healthcare 179.200 NA NA 7.70 6.25 NA 23.270 23.000 63.48 0.680 1.17 0 NA 4.01 5.29

Biotechnology & Drugs ERGO Ergo Science Corporation OTC Healthcare 7.500 NA NA 1.29 0.39 NA 5.810 5.500 2.24 0.000 5.40 0 NA NA 1.17

Biotechnology & Drugs EXAS EXACT Sciences Corporation NASD Healthcare 47.800 -0.06 50.00 1.82 1.57 NA 26.270 22.300 43.81 -0.980 15.10 0 NA 0.14 6.93

Biotechnology & Drugs EXEG eXegenics Inc. OTC Healthcare 6.510 NA NA 0.40 0.71 NA 16.270 15.300 4.73 0.010 5.95 0 NA NA 58.41

Biotechnology & Drugs EXEL Exelixis, Inc. NASD Healthcare 585.730 -0.39 15.00 7.65 20.51 NA 76.570 54.100 77.66 1.870 29.34 -9 NA 5.17 2.15

Biotechnology & Drugs EYET Eyetech Pharmaceuticals, Inc. NASD Healthcare 808.120 NA NA 17.96 6.18 NA 45.000 35.100 63.37 -4.720 21.99 -14 NA 0.02 4.08

Biotechnology & Drugs FVRL Favrille, Inc. NASD Healthcare 92.360 NA NA 4.55 1.77 NA 20.300 7.700 8.40 -0.730 62.06 3 NA 0.13 8.61

Biotechnology & Drugs FHRX First Horizon Pharmaceutical Corp. NASD Healthcare 696.700 0.69 30.03 19.87 2.17 24.07 35.060 28.100 95.00 5.330 19.86 0 NA 0.47 5.97

Biotechnology & Drugs FLML Flamel Technologies S.A. (ADR) NASD Healthcare 438.260 NA NA 18.70 4.17 448.23 23.440 22.700 46.53 -1.050 3.15 0 NA 0.03 3.83

Biotechnology & Drugs FMTI Forbes Medi-Tech Inc. (USA) NASD Healthcare 68.540 NA NA 2.01 2.82 NA 34.100 33.800 7.87 -0.070 0.88 0 NA 0.04 3.27





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BioTech Industry 30Sep05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs FRX Forest Laboratories, Inc. NYSE Healthcare 13,245.470 1.19 14.10 38.97 4.44 17.25 339.890 334.700 90.89 -1.600 1.53 -1 NA NA 5.31

Biotechnology & Drugs GGEN GalaGen Inc. OTC Healthcare 0.020 NA NA 0.00 NA NA 12.280 7.500 0.08 0.000 38.90 0 NA NA 0.37

Biotechnology & Drugs GCAN GammaCan International, Inc. OTC Healthcare 26.760 NA NA 1.02 27.57 NA 26.230 21.200 NA NA 19.18 NA NA NA 10.72

Biotechnology & Drugs GSAC GelStat Corporation OTC Healthcare 5.220 NA NA 0.35 3.15 NA 14.930 14.800 1.64 0.010 0.84 2 NA 0.28 2.04

Biotechnology & Drugs GENR Genaera Corporation NASD Healthcare 131.690 NA NA 1.92 5.96 NA 68.620 67.800 17.34 -3.380 1.20 0 NA NA 7.32

Biotechnology & Drugs GNSC Genaissance Pharm. Inc. NASD Healthcare 49.220 NA NA 1.39 3.60 NA 35.410 24.600 24.01 -0.440 30.53 0 NA 0.31 1.50

Biotechnology & Drugs GLGC Gene Logic Inc. NASD Healthcare 155.270 NA NA 4.89 0.93 NA 31.750 31.200 43.12 0.530 1.74 3 NA 0.01 3.36

Biotechnology & Drugs GNLB Genelabs Technologies NASD Healthcare 56.880 NA NA 0.64 7.71 NA 88.870 82.800 15.09 -6.220 6.83 0 NA 0.04 2.72

Biotechnology & Drugs GMXX GeneMax Corporation OTC Healthcare 3.500 NA NA 0.12 NA NA 29.170 21.700 0.00 0.000 25.61 0 NA NA 0.13

Biotechnology & Drugs DNA Genentech, Inc. NYSE Healthcare 89,623.250 2.07 34.09 84.21 11.23 88.94 1,064.280 458.900 40.50 14.170 56.88 -61 NA 0.06 3.45

Biotechnology & Drugs GNBT Generex Biotechnology NASD Healthcare 26.740 NA NA 0.67 4.25 NA 39.790 34.200 1.58 0.010 14.05 1 NA 0.79 0.16

Biotechnology & Drugs GBI Genesis Bioventures, Inc. AMEX Healthcare 3.370 NA NA 0.11 13.75 NA 30.660 20.500 0.02 0.010 33.14 0 NA 14.43 0.03

Biotechnology & Drugs GTOP Genitope Corporation NASD Healthcare 196.170 NA NA 6.94 1.93 NA 28.270 24.400 39.35 0.420 13.68 -10 NA 0.00 24.52

Biotechnology & Drugs GHDX Genomic Health, Inc. NASD Healthcare 281.440 NA NA 11.55 NA NA 24.370 5.020 NA NA 79.41 NA NA 0.14 6.34

Biotechnology & Drugs GNTA Genta Incorporated NASD Healthcare 143.040 NA NA 1.50 8.07 5.48 95.360 93.900 12.93 -2.560 1.53 2 NA 0.01 2.53

Biotechnology & Drugs GNT Gentium S.p.A. (ADR) AMEX Healthcare 57.500 NA NA 7.41 3.96 NA 7.760 1.900 NA NA 75.51 NA NA 0.45 1.75

Biotechnology & Drugs GNVC GenVec, Inc. NASD Healthcare 130.100 NA NA 2.05 4.68 NA 63.460 46.400 17.75 -0.410 26.89 1 NA 0.16 3.63

Biotechnology & Drugs GENZ Genzyme Corporation NASD Healthcare 18,388.080 1.63 19.50 71.64 3.91 129.39 256.670 231.400 90.85 11.240 9.85 -26 NA 0.25 2.42

Biotechnology & Drugs GORX GeoPharma, Inc. NASD Healthcare 31.050 NA NA 3.45 1.86 NA 9.000 5.500 22.13 1.140 38.89 -2 NA 0.19 2.63

Biotechnology & Drugs GERN Geron Corporation NASD Healthcare 645.100 NA NA 10.27 4.33 NA 62.810 59.900 20.77 0.330 4.64 -3 NA 0.01 23.55

Biotechnology & Drugs GILD Gilead Sciences, Inc. NASD Healthcare 22,231.050 1.62 19.55 48.76 9.28 39.32 455.930 451.700 91.22 19.190 0.93 -20 NA 0.00 9.13

Biotechnology & Drugs GLIAQ Gliatech Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 9.680 7.800 0.05 0.000 19.45 0 NA NA 0.90

Biotechnology & Drugs GLGS GlycoGenesys, Inc. NASD Healthcare 13.270 NA NA 1.03 4.46 NA 12.880 10.200 2.49 -0.050 20.83 0 NA NA 1.97

Biotechnology & Drugs GPCB GPC Biotech AG (ADR) NASD Healthcare 380.160 NA NA 12.64 2.47 NA 30.080 27.100 0.99 0.000 9.90 0 NA 0.01 11.37

Biotechnology & Drugs GTCB GTC Biotherapeutics, Inc. NASD Healthcare 65.180 NA NA 1.39 2.27 NA 46.890 40.900 14.52 -1.300 12.78 4 NA 0.44 1.38

Biotechnology & Drugs GTXI GTx, Inc. NASD Healthcare 229.630 NA NA 9.31 5.07 NA 24.660 7.700 22.46 -0.050 68.78 1 NA 0.00 5.67

Biotechnology & Drugs GLFD Guilford Pharmaceuticals NASD Healthcare 170.010 NA 0.00 3.65 NA NA 46.580 43.900 67.19 -2.870 5.75 5 NA NA 2.90

Biotechnology & Drugs HTI Halozyme Therapeutics, Inc. AMEX Healthcare 105.920 NA NA 2.12 11.46 NA 49.960 45.700 15.12 1.130 8.53 6 NA NA 6.15

Biotechnology & Drugs HBX Hana Biosciences, Inc. AMEX Healthcare 77.850 NA NA 4.25 11.24 NA 18.320 13.600 0.00 -1.700 25.75 7 NA NA 9.96

Biotechnology & Drugs VGENQ Harvard Scientific Corp. OTC Healthcare 0.000 NA NA 0.00 NA NA 29.330 5.900 NA NA 79.88 NA NA NA NA

Biotechnology & Drugs HDVY Health Discovery Corporation OTC Healthcare 16.440 NA NA 0.15 6.59 NA 113.360 75.900 NA NA 33.04 NA NA 0.67 0.46

Biotechnology & Drugs HESG Health Sciences Group, Inc. OTC Healthcare 18.620 NA NA 0.77 NA NA 24.190 12.300 NA NA 49.15 NA NA NA 0.35

Biotechnology & Drugs HCTL Healthcare Technologies NASD Healthcare 5.990 NA NA 0.78 NA NA 7.700 2.800 0.27 0.010 63.65 0 NA NA NA

Biotechnology & Drugs HXBM Helix BioMedix, Inc. OTC Healthcare 20.790 NA NA 1.03 4.12 NA 20.180 17.000 0.14 0.030 15.78 0 NA NA 16.77

Biotechnology & Drugs HEMA HemaCare Corporation OTC Healthcare 11.930 NA NA 1.46 1.98 8.22 8.170 7.900 1.13 -0.020 3.26 1 NA 0.14 2.25

Biotechnology & Drugs HMGN Hemagen Diagnostics, Inc. OTC Healthcare 3.800 NA NA 0.25 NA NA 15.200 12.400 0.42 0.020 18.44 2 NA NA 1.89

Biotechnology & Drugs HEB Hemispherx BioPharma, Inc AMEX Healthcare 87.030 NA NA 1.70 5.90 NA 51.190 44.000 4.92 0.070 14.05 6 NA 0.32 2.60

Biotechnology & Drugs HMSL Hemosol Corp. (USA) NASD Healthcare 11.680 NA NA 0.77 0.23 NA 15.170 13.500 8.37 1.270 11.01 0 NA 0.35 2.57

Biotechnology & Drugs HSKA Heska Corporation NASD Healthcare 44.330 NA NA 0.89 80.91 NA 49.810 29.100 36.97 -0.270 41.58 9 NA 21.34 1.03

Biotechnology & Drugs HITK Hi-Tech Pharmacal Co. NASD Healthcare 236.880 NA NA 30.08 3.30 29.31 7.880 6.000 45.88 0.330 23.81 -11 NA NA 5.32

Biotechnology & Drugs HEPH Hollis-Eden Pharmaceuticals Inc. NASD Healthcare 132.220 -0.08 50.00 6.39 2.42 NA 20.690 18.900 27.78 -0.010 8.66 -8 NA NA 13.43

Biotechnology & Drugs HSP Hospira, Inc. NYSE Healthcare 6,550.520 3.05 7.20 40.97 5.44 25.00 159.890 158.300 68.42 9.490 0.99 1 NA 0.58 2.54

Biotechnology & Drugs HBSC Human BioSystems OTC Healthcare 28.940 NA NA 0.54 NA NA 53.590 53.300 0.00 0.000 0.53 -17 NA NA 0.37

Biotechnology & Drugs HGSI Human Genome Sciences NASD Healthcare 1,776.540 -0.49 15.00 13.59 3.32 NA 130.720 127.900 89.77 10.510 2.16 0 NA 0.95 9.33

Biotechnology & Drugs ICGN Icagen, Inc. NASD Healthcare 146.650 NA 0.00 6.75 3.40 NA 21.730 21.730 18.49 0.180 0.00 0 NA 0.03 8.77

Biotechnology & Drugs ICLR ICON plc (ADR) NASD Healthcare 693.920 1.11 20.00 50.00 NA 52.37 13.880 13.600 72.95 -0.160 2.00 0 NA NA NA

Biotechnology & Drugs ICOR Icoria, Inc. OTC Healthcare 10.030 NA NA 0.25 0.99 NA 39.500 36.400 1.06 -1.590 7.85 0 NA 0.60 1.59

Biotechnology & Drugs ICOS ICOS Corporation NASD Healthcare 1,768.600 -0.89 25.00 27.62 NA NA 64.030 63.700 67.82 1.370 0.52 0 NA NA 8.45

Biotechnology & Drugs IDBE ID Biomedical Corporation (USA) NASD Healthcare 1,293.730 NA NA 30.05 14.02 NA 43.050 42.200 18.21 0.140 1.98 0 NA 1.36 1.66

Biotechnology & Drugs IDIX Idenix Pharmaceuticals, Inc. NASD Healthcare 1,210.670 -0.45 40.00 25.10 13.32 NA 48.230 13.700 22.13 2.430 71.60 0 NA 0.03 4.83

Biotechnology & Drugs IDP Idera Pharmaceuticals Inc. AMEX Healthcare 74.440 NA NA 0.67 11.96 NA 111.100 91.100 NA NA 18.00 NA NA 0.81 4.53

Biotechnology & Drugs IDXX IDEXX Laboratories, Inc. NASD Healthcare 2,177.200 2.04 14.25 66.88 5.55 31.25 32.550 32.500 90.96 -0.420 0.17 -10 NA 0.00 3.30

Biotechnology & Drugs IG IGI, Inc. AMEX Healthcare 11.380 NA NA 0.94 2.85 NA 12.110 8.300 3.73 0.070 31.46 0 NA NA 1.89

Biotechnology & Drugs IMCL ImClone Systems Incorporated NASD Healthcare 2,634.410 2.32 11.29 31.45 10.84 34.48 83.760 69.200 64.92 -4.050 17.39 -6 NA 2.47 4.26

Biotechnology & Drugs ICRP IMCOR Pharmaceutical Co. OTC Healthcare 0.500 NA NA 0.10 0.27 NA 4.960 2.500 NA NA 49.56 NA NA 0.10 0.09

Biotechnology & Drugs IMM Immtech International, Inc. AMEX Healthcare 134.380 NA NA 11.66 138.81 NA 11.520 8.800 8.43 0.080 23.64 0 NA NA 2.46

Biotechnology & Drugs ICCC ImmuCell Corporation NASD Healthcare 14.260 NA NA 5.01 1.74 41.66 2.850 2.400 0.35 0.010 15.70 0 NA NA 7.42

Biotechnology & Drugs IMMFF Immune Network Ltd. OTC Healthcare 0.370 NA NA 0.02 NA NA 20.920 12.800 NA NA 38.81 NA NA NA 0.05

Biotechnology & Drugs IMGN ImmunoGen, Inc. NASD Healthcare 301.480 NA NA 7.34 3.47 NA 41.070 40.500 37.96 1.000 1.40 0 NA NA 10.83

Biotechnology & Drugs IMMU Immunomedics, Inc. NASD Healthcare 110.850 NA NA 2.05 NA NA 54.070 44.800 23.00 -3.380 17.15 -1 NA NA 3.48

Biotechnology & Drugs IPXL Impax Laboratories Inc. OTC Healthcare 709.420 5.22 26.25 12.13 8.22 1,501.24 58.480 40.000 72.06 0.750 31.61 0 NA 1.25 4.44

Biotechnology & Drugs INCY Incyte Corporation NASD Healthcare 392.040 -0.24 15.00 4.70 11.61 NA 83.410 75.900 79.75 2.680 9.01 1 NA 10.36 15.09

Biotechnology & Drugs IDEV Indevus Pharmaceuticals NASD Healthcare 135.380 NA NA 2.88 NA NA 47.010 40.800 35.27 -4.060 13.20 0 NA NA 4.15

Biotechnology & Drugs INHX Inhibitex, Inc. NASD Healthcare 307.360 NA NA 10.18 4.21 NA 30.200 12.600 17.17 0.320 58.28 0 NA 0.08 6.87

Biotechnology & Drugs INKP InKine Pharmaceutical Company, Inc. NASD Healthcare 180.850 NA NA 3.65 12.54 109.15 49.550 48.300 35.73 -2.570 2.52 0 NA NA 4.73





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 30Sep05 13 of 45 10/24/2011 3:30 PM

BioTech Industry 30Sep05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs ISV Insite Vision Inc. AMEX Healthcare 50.490 NA NA 0.64 12.80 NA 78.890 68.900 10.18 1.980 12.67 0 NA 0.08 2.29

Biotechnology & Drugs INSM Insmed Incorporated NASD Healthcare 60.420 NA NA 1.34 6.63 NA 45.090 42.200 14.71 -2.680 6.41 0 NA 2.17 7.35

Biotechnology & Drugs ISPH Inspire Pharmaceuticals, Inc. NASD Healthcare 319.740 -0.27 30.00 7.60 2.43 NA 42.070 41.500 89.19 -0.760 1.36 0 NA 0.01 12.98

Biotechnology & Drugs INB Integrated BioPharma, Inc. AMEX Healthcare 26.020 NA NA 2.06 1.35 NA 12.630 5.900 2.95 -0.100 53.29 0 NA 0.22 2.01

Biotechnology & Drugs IFSC Interferon Sciences, Inc. OTC Healthcare 4.850 NA NA 0.13 8.67 NA 37.340 20.900 0.63 0.070 44.03 0 NA 0.39 1.69

Biotechnology & Drugs ITMN InterMune, Inc. NASD Healthcare 539.340 NA NA 16.55 NA NA 32.590 25.400 83.93 0.490 22.06 1 NA NA 3.45

Biotechnology & Drugs INIS International Isotopes Inc. OTC Healthcare 12.850 NA NA 0.07 14.00 NA 183.630 115.000 0.00 0.000 37.38 5 NA 1.37 1.13

Biotechnology & Drugs IPA Interpharm Holdings, Inc. AMEX Healthcare 35.710 NA NA 1.37 1.51 NA 26.060 19.300 3.01 -0.120 25.95 4 NA 0.57 1.35

Biotechnology & Drugs IBCL Int'l BioChemical Industries, Inc. OTC Healthcare 0.010 NA NA 0.00 NA NA 94.160 92.500 0.01 0.000 1.77 0 NA NA 0.02

Biotechnology & Drugs IBPI IntraBiotics Pharmaceuticals NASD Healthcare 33.280 NA NA 3.66 0.71 NA 9.090 7.300 54.47 -0.010 19.73 15 NA NA 133.09

Biotechnology & Drugs INGN Introgen Therapeutics, Inc NASD Healthcare 173.950 NA NA 5.22 8.72 NA 33.320 22.200 28.37 1.480 33.38 -11 NA 0.43 4.38

Biotechnology & Drugs IMA Inverness Medical Innovations, Inc. AMEX Healthcare 725.370 NA NA 26.53 1.93 NA 27.340 22.100 38.68 -0.470 19.17 -2 NA 0.81 1.59

Biotechnology & Drugs IVRO InVitro International OTC Healthcare 0.350 NA NA 0.02 0.86 26.67 14.510 9.000 NA NA 37.96 NA NA NA 9.37

Biotechnology & Drugs IVGN Invitrogen Corporation NASD Healthcare 3,992.150 1.53 14.00 75.23 1.98 35.00 53.070 52.600 95.00 3.270 0.88 -8 NA 0.77 6.62

Biotechnology & Drugs IOX IOMED, Inc. AMEX Healthcare 16.260 NA NA 2.47 NA 44.49 6.590 4.000 7.02 0.250 39.26 -1 NA NA NA

Biotechnology & Drugs ISIS ISIS Pharmaceuticals, Inc. NASD Healthcare 291.310 NA NA 5.05 NA NA 57.680 51.800 52.00 -0.190 10.20 -10 NA NA 2.78

Biotechnology & Drugs ILE Isolagen, Inc. AMEX Healthcare 49.930 -0.10 15.00 1.65 4.21 NA 30.260 28.400 41.09 -2.390 6.15 3 NA 7.59 11.10

Biotechnology & Drugs ISTA ISTA Pharmaceuticals NASD Healthcare 171.700 -0.16 26.67 6.64 3.44 NA 25.860 18.800 90.73 7.020 27.30 -12 NA 0.00 7.32

Biotechnology & Drugs ITER IT&E International Group OTC Healthcare 3.630 NA NA 0.17 7.08 NA 21.340 21.100 NA NA 1.14 NA NA 9.20 2.27

Biotechnology & Drugs ITXFF Iteration Energy, Ltd. (USA) OTC Healthcare 251.430 NA NA 5.15 2.19 NA 48.820 45.400 NA NA 7.01 NA NA 0.01 4.55

Biotechnology & Drugs IVX IVAX Corporation AMEX Healthcare 7,088.640 1.45 22.55 26.36 4.45 38.86 268.920 153.600 66.51 22.610 42.88 -1 NA 0.90 2.84

Biotechnology & Drugs KNDL Kendle International Inc. NASD Healthcare 379.700 NA NA 28.14 3.59 61.01 13.490 11.200 57.88 -0.070 16.99 2 NA 0.06 1.96

Biotechnology & Drugs KERX Keryx Biopharmaceuticals NASD Healthcare 590.270 -0.99 25.00 15.76 15.05 NA 37.450 30.900 54.04 0.100 17.50 0 NA NA 7.62

Biotechnology & Drugs KG King Pharmaceuticals NYSE Healthcare 3,717.930 1.58 7.18 15.38 1.92 37.56 241.740 239.800 75.65 1.290 0.80 0 NA 0.18 1.99

Biotechnology & Drugs KOSP KOS Pharmaceuticals, Inc. NASD Healthcare 3,067.300 1.12 21.83 66.93 5.42 19.90 45.830 17.800 39.75 2.190 61.16 -47 NA 0.00 2.59

Biotechnology & Drugs KOSN Kosan Biosciences Incorporated NASD Healthcare 212.670 NA NA 7.27 3.90 NA 29.250 22.700 48.21 -0.950 22.40 0 NA 0.08 4.51

Biotechnology & Drugs KV.A K-V Pharmaceutical Company NYSE Healthcare 876.040 1.04 22.38 17.77 3.24 890.28 49.300 36.200 58.73 -4.130 26.57 -6 NA 0.78 9.47

Biotechnology & Drugs LJPC La Jolla Pharmaceutical Company NASD Healthcare 56.270 NA NA 0.76 2.11 NA 74.040 73.800 13.06 -6.490 0.32 0 NA 0.04 5.68

Biotechnology & Drugs LCI Lannett Company, Inc. AMEX Healthcare 124.690 NA NA 5.17 1.80 NA 24.120 10.100 4.28 -0.230 58.12 6 NA 0.14 2.07

Biotechnology & Drugs LSBC Large Scale Biology Corp. NASD Healthcare 26.700 NA NA 0.83 7.48 NA 32.170 24.900 7.39 -0.650 22.59 0 NA 1.51 0.16

Biotechnology & Drugs LCAR Lescarden Inc. OTC Healthcare 12.360 NA NA 0.40 NA 30.94 30.910 15.800 0.06 0.000 48.88 0 NA NA 1.01

Biotechnology & Drugs LEXG Lexicon Genetics Incorporated NASD Healthcare 253.030 NA NA 3.97 2.70 NA 63.740 57.700 52.32 -0.160 9.47 -1 NA 0.40 2.02

Biotechnology & Drugs LSRI Life Sciences Research Inc. OTC Healthcare 189.690 1.35 25.00 15.12 360.00 15.13 12.550 9.400 13.09 0.220 25.08 1 NA 145.94 0.94

Biotechnology & Drugs LIFC LifeCell Corporation NASD Healthcare 694.020 1.40 39.50 21.63 8.93 64.28 32.090 32.000 72.66 5.420 0.27 -1 NA NA 6.97

Biotechnology & Drugs LCBM Lifecore Biomedical, Inc. NASD Healthcare 157.660 1.17 21.83 12.09 2.33 9.31 13.040 12.000 61.17 -0.080 7.98 2 NA 0.08 6.23

Biotechnology & Drugs LGND Ligand Pharmaceuticals OTC Healthcare 749.410 -3.05 36.10 10.14 18.26 NA 73.930 69.500 78.55 -0.360 6.00 0 NA 4.25 1.75

Biotechnology & Drugs LIPD Lipid Sciences, Inc. NASD Healthcare 74.020 NA NA 2.97 6.14 NA 24.920 17.400 4.34 0.030 30.18 0 NA NA 5.87

Biotechnology & Drugs LRP Lorus Therapeutics Inc. (USA) AMEX Healthcare 108.750 NA NA 0.63 9.50 NA 172.620 170.900 3.08 2.140 1.00 0 NA 0.77 5.53

Biotechnology & Drugs LMNX Luminex Corporation NASD Healthcare 317.260 NA NA 10.04 6.90 NA 31.600 28.400 38.95 0.490 10.13 2 NA NA 7.89

Biotechnology & Drugs MCHM MacroChem Corporation NASD Healthcare 2.140 NA NA 0.05 0.57 NA 41.860 40.900 12.93 -4.530 2.30 0 NA NA 5.65

Biotechnology & Drugs MHTT Manhattan Pharmaceuticals, Inc. OTC Healthcare 67.110 NA NA 1.30 65.00 NA 51.620 19.600 3.62 0.020 62.03 25 NA 0.39 1.36

Biotechnology & Drugs MTEX Mannatech, Inc. NASD Healthcare 319.840 NA NA 11.85 5.34 15.40 26.990 16.500 16.49 -0.030 38.87 -5 2.36 0.00 1.63

Biotechnology & Drugs MNKD MannKind Corporation NASD Healthcare 687.060 NA NA 13.69 4.56 NA 50.190 25.400 10.03 0.670 49.39 6 NA NA 2.81

Biotechnology & Drugs MSHL Marshall Edwards, Inc. NASD Healthcare 330.810 NA NA 5.81 20.03 NA 56.940 6.800 1.09 0.130 88.06 0 NA NA 6.81

Biotechnology & Drugs MATK Martek Biosciences Corp. NASD Healthcare 1,114.170 2.40 33.75 35.13 2.45 23.56 31.720 30.500 95.00 -1.460 3.83 -6 NA 0.16 4.43

Biotechnology & Drugs MZT Matritech, Inc. AMEX Healthcare 28.560 NA NA 0.63 6.70 NA 45.330 44.600 6.39 -0.780 1.62 3 NA 0.23 2.37

Biotechnology & Drugs MTXX Matrixx Initiatives, Inc. NASD Healthcare 135.300 0.66 31.50 14.22 3.01 23.72 9.520 8.400 46.25 0.330 11.72 -10 NA 0.00 3.93

Biotechnology & Drugs MAXM Maxim Pharmaceuticals NASD Healthcare 38.330 NA NA 1.34 1.21 NA 28.610 28.500 10.25 -2.170 0.37 0 NA 0.01 6.68

Biotechnology & Drugs MAXY Maxygen, Inc. NASD Healthcare 296.690 NA NA 8.29 1.40 NA 35.790 26.200 34.56 -0.270 26.79 -19 NA 0.00 25.80

Biotechnology & Drugs MDZ MDS Inc. (USA) NYSE Healthcare 2,545.950 1.92 15.00 17.96 1.90 35.68 141.760 95.000 58.90 7.250 32.98 0 0.62 0.32 1.82

Biotechnology & Drugs MEDX Medarex, Inc. NASD Healthcare 1,057.040 NA NA 9.52 5.25 NA 111.030 109.800 56.96 3.180 1.11 -4 NA 0.74 10.11

Biotechnology & Drugs MLSC Medical Discoveries, Inc. OTC Healthcare 12.940 NA NA 0.12 NA NA 107.830 84.700 0.00 0.000 21.45 0 NA NA 0.67

Biotechnology & Drugs MRX Medicis Pharmaceutical Corporation NYSE Healthcare 1,770.840 1.18 19.37 32.56 3.64 31.79 54.390 53.400 NA NA 1.82 0 0.37 0.93 7.07

Biotechnology & Drugs MCU Medicure Inc. (USA) AMEX Healthcare 65.490 NA NA 0.98 10.34 NA 66.830 58.800 5.62 0.740 12.01 0 NA NA 3.17

Biotechnology & Drugs MHUT Medi-Hut Co., Inc. OTC Healthcare 1.300 NA NA 0.09 0.08 0.88 14.470 10.400 0.38 0.000 28.11 3 NA NA 2.66

Biotechnology & Drugs MEDI MedImmune, Inc. NASD Healthcare 8,289.070 5.13 24.75 33.65 4.94 160.87 246.330 245.000 88.36 8.420 0.54 0 NA 0.30 3.33

Biotechnology & Drugs TOX MEDTOX Scientific, Inc. AMEX Healthcare 57.690 1.05 20.00 7.25 1.39 27.40 7.960 7.400 34.86 0.000 7.00 4 NA 0.34 1.37

Biotechnology & Drugs MEMY Memory Pharmaceuticals Corp. NASD Healthcare 57.010 NA NA 2.71 4.59 NA 21.040 17.000 38.22 -0.030 19.19 11 NA 0.24 2.08

Biotechnology & Drugs VIVO Meridian Bioscience, Inc. NASD Healthcare 496.960 2.38 17.50 20.70 10.07 41.84 24.010 17.700 41.15 1.280 26.28 -19 1.55 0.21 1.85

Biotechnology & Drugs MBRX Metabasis Therapeutics, Inc. NASD Healthcare 106.260 NA NA 5.83 3.43 NA 18.230 9.700 31.10 1.890 46.78 0 NA 0.07 5.72

Biotechnology & Drugs MOGN MGi Pharma, Inc. NASD Healthcare 1,673.240 0.89 44.67 23.24 12.08 NA 72.000 71.800 92.11 1.210 0.28 -1 NA 1.88 10.29

Biotechnology & Drugs MLAR Micro Laboratories, Inc. OTC Healthcare 1.970 NA NA 0.03 NA 60.00 59.620 9.500 NA NA 84.07 NA NA NA 0.00

Biotechnology & Drugs MII MicroIslet, Inc. AMEX Healthcare 87.880 NA NA 2.20 12.50 NA 39.940 24.900 5.23 -0.180 37.66 0 NA NA 24.06

Biotechnology & Drugs MLNM Millennium Pharmaceuticals, Inc. NASD Healthcare 2,879.290 -1.55 18.25 9.33 1.31 NA 308.610 299.400 71.77 19.250 2.98 -3 NA 0.09 4.28

Biotechnology & Drugs MRVT Miravant Medical Technologies OTC Healthcare 14.450 NA NA 0.39 NA NA 37.530 35.900 2.74 -2.210 4.35 0 NA NA 2.54





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 30Sep05 14 of 45 10/24/2011 3:30 PM

BioTech Industry 30Sep05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs MNTA Momenta Pharmaceuticals, Inc. NASD Healthcare 827.200 NA NA 27.25 13.96 NA 30.360 15.500 27.70 4.730 48.94 -21 NA 0.06 8.33

Biotechnology & Drugs MGRM Monogram Biosciences Inc. NASD Healthcare 296.900 NA NA 2.35 4.06 NA 126.340 125.500 0.00 0.000 0.67 -3 NA 0.06 2.93

Biotechnology & Drugs MCET MultiCell Technologies, Inc. OTC Healthcare 25.590 NA NA 0.81 5.29 NA 31.590 22.200 0.00 0.000 29.73 -6 NA 0.08 3.59

Biotechnology & Drugs MYL Mylan Laboratories Inc. NYSE Healthcare 4,210.270 1.16 16.73 19.26 2.24 31.98 218.600 205.100 77.73 -17.830 6.18 -5 1.25 0.01 5.93

Biotechnology & Drugs MYMX Mymetics Corporation OTC Healthcare 10.310 NA NA 0.06 NA NA 171.870 118.600 0.16 -0.030 30.99 0 NA NA 0.02

Biotechnology & Drugs MYOG Myogen, Inc. NASD Healthcare 950.720 -0.58 20.00 23.50 12.25 NA 40.460 25.300 59.23 1.320 37.46 -18 NA 0.02 3.53

Biotechnology & Drugs MYGN Myriad Genetics, Inc. NASD Healthcare 675.410 NA NA 21.86 4.97 NA 30.900 28.400 68.14 -0.790 8.08 0 NA NA 5.82

Biotechnology & Drugs NABI Nabi Biopharmaceuticals NASD Healthcare 775.030 -0.33 30.00 13.10 3.09 NA 59.160 58.800 84.71 4.890 0.61 1 NA 0.49 3.88

Biotechnology & Drugs NSTK Nastech Pharmaceutical NASD Healthcare 266.140 NA NA 14.14 5.62 NA 18.820 13.300 32.45 1.780 29.34 -23 NA 0.09 5.22

Biotechnology & Drugs NHCT National Healthcare Technology, Inc. OTC Healthcare 40.510 NA NA 2.20 NA NA 18.410 8.500 NA NA 53.84 NA NA NA NA

Biotechnology & Drugs NTOL Natrol, Inc. NASD Healthcare 31.780 NA NA 2.35 0.84 105.10 13.520 6.700 41.00 0.260 50.46 -11 NA 0.21 3.40

Biotechnology & Drugs NAII Natural Alternatives International, Inc. NASD Healthcare 41.020 NA NA 6.87 1.53 20.26 5.970 4.600 7.37 0.020 22.96 1 NA 0.14 2.13

Biotechnology & Drugs NAWL Naturewell, Inc. OTC Healthcare 0.590 NA NA 0.01 NA NA 118.220 72.100 0.00 0.000 39.01 0 NA NA 0.02

Biotechnology & Drugs NTY NBTY, Inc. NYSE Healthcare 1,578.920 1.16 14.00 23.50 2.24 18.51 67.190 56.600 78.15 1.590 15.76 -6 NA 0.42 3.00

Biotechnology & Drugs NEOG Neogen Corporation NASD Healthcare 146.920 1.30 16.50 18.00 2.67 25.83 8.160 7.000 24.98 -0.170 14.24 -11 NA 0.00 4.95

Biotechnology & Drugs NEOL NeoPharm, Inc. NASD Healthcare 292.600 NA 0.00 12.40 7.13 NA 23.600 18.800 70.22 -0.540 20.33 1 NA NA 5.65

Biotechnology & Drugs NEOP Neoprobe Corporation OTC Healthcare 17.580 NA NA 0.30 2.68 NA 58.590 53.400 0.37 0.200 8.85 5 NA 0.02 8.05

Biotechnology & Drugs NERX NeoRx Corporation NASD Healthcare 31.490 NA NA 0.92 3.02 NA 34.230 31.700 5.84 -0.950 7.39 1 NA 0.39 3.86

Biotechnology & Drugs NTEC Neose Technologies, Inc. NASD Healthcare 77.040 NA NA 2.35 1.10 NA 32.780 30.800 55.99 -1.240 6.05 2 NA 0.24 5.37

Biotechnology & Drugs NTII Neurobiological Tech. NASD Healthcare 103.070 NA NA 3.81 NA NA 27.050 24.000 26.06 0.310 11.29 3 NA NA NA

Biotechnology & Drugs NRMX Neurochem Inc. (USA) NASD Healthcare 440.890 NA NA 12.75 6.72 NA 34.580 22.600 20.72 -0.370 34.64 0 NA 0.13 4.63

Biotechnology & Drugs NBIX Neurocrine Biosciences, Inc. NASD Healthcare 1,810.210 -1.58 32.50 49.19 4.85 NA 36.800 35.700 95.00 4.520 2.99 -5 NA 0.17 6.74

Biotechnology & Drugs NRGN Neurogen Corporation NASD Healthcare 237.930 NA NA 6.88 1.77 NA 34.580 26.000 37.38 0.250 24.82 -3 NA 0.09 14.34

Biotechnology & Drugs NRGX Neurologix, Inc. OTC Healthcare 49.090 NA NA 1.85 7.97 NA 26.530 15.900 27.47 0.010 40.08 -8 NA 0.00 24.17

Biotechnology & Drugs NRPH New River Pharmaceuticals, Inc. NASD Healthcare 863.350 NA NA 47.94 95.50 NA 18.010 6.100 20.11 0.560 66.13 -72 NA 0.01 16.94

Biotechnology & Drugs BBAL New York Health Care, Inc. OTC Healthcare 33.230 NA NA 1.00 4.48 NA 33.230 32.600 NA NA 1.91 NA NA NA 1.23

Biotechnology & Drugs NEXM NexMed, Inc. NASD Healthcare 82.550 NA NA 1.59 23.38 NA 51.920 50.000 21.43 0.430 3.69 5 NA 0.96 3.18

Biotechnology & Drugs NTMD NitroMed, Inc. NASD Healthcare 546.710 NA 0.00 18.00 5.69 NA 30.370 17.000 69.02 0.800 44.03 -1 NA 0.21 5.52

Biotechnology & Drugs NASI North American Scientific, Inc. NASD Healthcare 43.890 NA NA 2.62 0.80 NA 16.750 14.100 43.01 -0.270 15.83 3 NA NA 1.47

Biotechnology & Drugs NFLD Northfield Laboratories NASD Healthcare 345.090 -1.35 10.00 12.90 3.60 NA 26.750 24.500 21.86 -1.460 8.42 -2 NA NA 24.92

Biotechnology & Drugs NWBT Northwest Biotherapeutics OTC Healthcare 3.240 NA NA 0.17 NA NA 19.080 18.900 0.00 0.000 0.93 0 NA NA 0.04

Biotechnology & Drugs NVAX Novavax, Inc. NASD Healthcare 76.220 NA NA 1.75 3.72 NA 43.550 38.000 10.24 0.380 12.75 5 NA 1.95 1.48

Biotechnology & Drugs NOVN Noven Pharmaceuticals, Inc. NASD Healthcare 330.100 0.81 34.00 14.00 2.43 31.56 23.580 22.600 84.40 0.440 4.15 -1 NA 0.00 4.23

Biotechnology & Drugs NVO Novo Nordisk A/S (ADR) NYSE Healthcare 17,585.600 1.97 8.93 49.58 4.25 17.79 354.690 261.800 2.61 0.600 26.19 0 1.73 0.07 1.87

Biotechnology & Drugs NVGN Novogen Limited (ADR) NASD Healthcare 356.350 NA NA 18.35 8.22 NA 19.420 17.480 4.02 0.050 9.99 0 NA 0.01 8.48

Biotechnology & Drugs NPSP NPS Pharmaceuticals, Inc. NASD Healthcare 392.970 NA NA 10.11 NA NA 38.870 38.000 87.39 0.910 2.24 -9 NA NA 6.55

Biotechnology & Drugs NPHCE Nutra Pharma Corp. OTC Healthcare 18.090 NA NA 0.27 265.00 NA 68.250 60.700 NA NA 11.07 NA NA NA 0.20

Biotechnology & Drugs NUTR Nutraceutical Int'l Corp. NASD Healthcare 163.040 NA NA 14.22 2.08 13.15 11.470 10.900 71.28 -0.300 4.94 0 NA 0.06 3.08

Biotechnology & Drugs NXXI Nutrition 21, Inc. NASD Healthcare 34.320 NA NA 0.90 2.28 NA 38.140 32.000 2.03 -0.820 16.09 0 NA NA 3.45

Biotechnology & Drugs NUVO Nuvelo, Inc. NASD Healthcare 404.410 NA NA 9.60 4.86 NA 42.130 41.300 64.94 3.050 1.96 1 NA 0.17 3.48

Biotechnology & Drugs NYMX Nymox Pharmaceutical Corporation NASD Healthcare 56.330 NA NA 2.16 67.50 NA 26.080 12.500 0.52 0.050 52.07 0 NA 0.61 0.14

Biotechnology & Drugs ONCY Oncolytics Biotech, Inc. (USA) NASD Healthcare 126.850 NA NA 3.85 4.05 NA 32.950 32.600 11.27 0.160 1.05 0 NA 0.00 21.25

Biotechnology & Drugs ONCR Oncor, Inc. OTC Healthcare 0.020 NA NA 0.00 NA NA 33.550 24.500 0.15 0.000 26.98 0 NA NA 5.83

Biotechnology & Drugs ONXX Onyx Pharmaceuticals, Inc. NASD Healthcare 882.920 -0.51 18.00 24.97 6.02 NA 35.360 32.900 87.86 -0.160 6.95 0 NA 0.14 9.35

Biotechnology & Drugs ONI Oragenics, Inc. AMEX Healthcare 17.490 NA NA 1.15 7.67 NA 15.210 7.600 1.28 0.000 50.03 1 NA 0.16 4.25

Biotechnology & Drugs ORCH Orchid Cellmark, Inc. NASD Healthcare 208.470 -4.05 30.00 8.50 3.84 NA 24.530 24.400 38.00 -3.260 0.51 0 NA 0.00 3.43

Biotechnology & Drugs ORCY Organic Recycling Technologies Inc. OTC Healthcare 11.050 NA NA 0.50 NA NA 22.090 20.300 NA NA 8.12 NA NA NA 0.14

Biotechnology & Drugs ORGT OrganiTECH USA, Inc. OTC Healthcare 4.240 NA NA 0.20 NA NA 21.220 6.800 NA NA 67.95 NA NA NA 0.34

Biotechnology & Drugs OSCI Oscient Pharmaceuticals Corporation NASD Healthcare 162.940 -0.06 30.00 2.12 2.44 NA 76.860 68.100 37.77 -0.600 11.39 -36 NA 2.62 5.13

Biotechnology & Drugs OSIP OSI Pharmaceuticals, Inc. NASD Healthcare 1,503.260 -0.67 26.67 29.24 3.05 NA 51.410 51.200 95.00 4.210 0.41 -18 NA 0.31 14.48

Biotechnology & Drugs OXGN OXiGENE, Inc. NASD Healthcare 105.620 NA NA 5.27 2.79 NA 20.040 19.400 12.23 -0.420 3.21 10 NA NA 15.90

Biotechnology & Drugs OXIS OXIS International, Inc. OTC Healthcare 15.680 NA NA 0.37 2.87 NA 42.370 11.200 0.07 -0.020 73.57 0 NA 0.00 7.14

Biotechnology & Drugs PBME Pacific Biometrics, Inc. OTC Healthcare 12.100 NA NA 0.90 NA NA 13.450 7.400 0.00 0.000 44.97 -4 NA NA 1.50

Biotechnology & Drugs PHLI PacificHealth Laboratories, Inc. OTC Healthcare 2.870 NA NA 0.28 NA NA 10.240 8.000 0.00 0.000 21.85 0 NA 10.12 0.98

Biotechnology & Drugs PTIE Pain Therapeutics, Inc. NASD Healthcare 275.840 NA NA 6.29 3.68 NA 43.850 30.100 42.72 -0.860 31.36 0 NA NA 9.90

Biotechnology & Drugs PTN Palatin Technologies, Inc. AMEX Healthcare 124.750 NA NA 2.30 13.53 NA 54.240 51.500 16.81 -1.510 5.05 3 NA 0.00 2.06

Biotechnology & Drugs PGNT Paligent Inc. OTC Healthcare 1.950 NA NA 0.06 NA 13.92 32.490 14.900 0.06 0.020 54.14 0 NA NA 0.26

Biotechnology & Drugs PANC Panacos Pharmaceuticals, Inc. NASD Healthcare 384.820 NA NA 9.74 29.97 NA 39.510 21.700 0.00 0.000 45.08 -21 NA 0.07 2.47

Biotechnology & Drugs PRX Par Pharmaceutical Companies, Inc NYSE Healthcare 910.380 2.82 11.80 26.62 2.12 NA 34.200 34.100 95.00 3.610 0.29 2 NA 0.47 3.51

Biotechnology & Drugs PRLN Paracelsian, Inc. OTC Healthcare 0.020 NA NA 0.00 NA NA 23.950 16.000 0.69 0.000 33.21 0 NA NA 0.03

Biotechnology & Drugs PRXL PAREXEL International Corporation NASD Healthcare 533.590 1.49 16.67 20.09 2.56 NA 26.560 26.400 95.00 0.350 0.60 3 NA 0.01 1.54

Biotechnology & Drugs PPCO Penwest Pharmaceuticals NASD Healthcare 381.080 NA NA 17.53 5.69 NA 21.740 21.700 71.54 -0.680 0.18 -3 NA 0.00 8.10

Biotechnology & Drugs PPHM Peregrine Pharmaceuticals NASD Healthcare 166.020 NA NA 1.00 10.00 NA 166.020 164.300 7.70 -6.210 1.04 10 NA 0.05 5.09

Biotechnology & Drugs PRGO Perrigo Company NASD Healthcare 1,338.490 2.23 8.57 14.31 2.27 NA 93.540 77.200 67.21 0.480 17.47 -1 1.12 1.15 1.79

Biotechnology & Drugs PHFRQ Pharmaceutical Formulations, Inc. OTC Healthcare 0.170 NA NA 0.00 NA NA 86.160 83.300 NA NA 3.32 NA NA NA 0.70





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 30Sep05 15 of 45 10/24/2011 3:30 PM

BioTech Industry 30Sep05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs PPDI NASD

Pharmaceutical Product Development, Inc. Healthcare 3,313.330 1.37 18.87 57.51 4.69 30.00 57.610 49.000 78.15 -0.150 14.95 -25 NA 0.01 1.91

Biotechnology & Drugs PCOP Pharmacopeia Drug Discovery, Inc. NASD Healthcare 53.330 NA NA 3.57 1.27 NA 14.940 14.400 58.20 -0.140 3.60 2 NA NA 3.33

Biotechnology & Drugs PCYC Pharmacyclics, Inc. NASD Healthcare 178.670 NA NA 9.02 2.55 NA 19.810 19.500 67.86 -0.460 1.56 0 NA NA 16.35

Biotechnology & Drugs PFTR PharmaFrontiers Corp. OTC Healthcare 25.700 NA NA 1.25 0.84 NA 20.560 19.200 NA NA 6.62 NA NA 0.05 2.14

Biotechnology & Drugs PPRT PharmaPrint Inc. OTC Healthcare 0.010 NA NA 0.00 NA NA 23.980 22.500 NA NA 6.19 NA NA NA 0.06

Biotechnology & Drugs PHRM Pharmion Corporation NASD Healthcare 694.280 0.84 44.25 21.81 1.96 59.69 31.830 26.400 69.38 1.200 17.07 0 NA NA 6.65

Biotechnology & Drugs PARS Pharmos Corporation NASD Healthcare 40.720 NA NA 2.14 0.80 NA 19.030 18.700 5.77 1.100 1.72 0 NA 0.00 21.66

Biotechnology & Drugs PLTT Pilot Therapeutics Holdings, Inc. OTC Healthcare 0.810 NA NA 0.07 NA NA 11.540 2.600 NA NA 77.48 NA NA NA 0.25

Biotechnology & Drugs PLRS Pluristem Life Systems, Inc. OTC Healthcare 8.270 NA NA 0.13 6.84 NA 63.600 47.100 NA NA 25.95 NA NA 0.00 7.01

Biotechnology & Drugs POTP Point Therapeutics, Inc. OTC Healthcare 98.550 NA NA 4.20 4.67 NA 23.470 22.700 28.98 0.290 3.26 0 NA NA 6.79

Biotechnology & Drugs POLXF Polydex Pharmaceuticals Limited NASD Healthcare 16.330 NA NA 5.35 2.01 NA 3.050 2.700 0.72 0.000 11.53 0 NA 0.12 3.17

Biotechnology & Drugs PROAQ Polymer Research Corp. of America OTC Healthcare 1.600 NA NA 0.75 5.10 NA 2.130 0.900 0.14 0.000 57.73 0 NA 6.88 0.69

Biotechnology & Drugs PWRM Power3 Medical Products, Inc. OTC Healthcare 15.680 NA NA 0.24 NA NA 65.350 23.500 0.00 0.000 64.04 0 NA NA 0.02

Biotechnology & Drugs POZN POZEN Inc. NASD Healthcare 317.780 NA NA 10.99 14.31 NA 28.920 25.000 41.20 0.400 13.54 2 NA NA 3.37

Biotechnology & Drugs PRAI PRA International NASD Healthcare 682.390 1.58 15.33 30.31 4.11 26.34 22.510 12.000 66.64 8.110 46.70 -11 NA NA 1.18

Biotechnology & Drugs PRCS Praecis Pharmaceuticals NASD Healthcare 24.660 NA NA 0.47 0.43 NA 52.470 46.200 29.56 -8.380 11.95 0 NA 0.55 5.75

Biotechnology & Drugs PRAN Prana Biotechnology Limited (ADR) NASD Healthcare 18.440 NA NA 1.45 0.65 NA 12.710 11.530 4.03 -1.510 9.31 0 NA NA 18.98

Biotechnology & Drugs PME PreMD Inc. AMEX Healthcare 45.000 NA NA 2.09 173.26 NA 21.530 19.200 NA NA 10.82 NA NA NA 2.99

Biotechnology & Drugs PBIO Pressure BioSciences, Inc. NASD Healthcare 11.540 NA NA 4.76 1.23 NA 2.420 2.400 0.62 -0.040 0.99 7 NA NA 5.12

Biotechnology & Drugs PGLAF Progen Industries Limited (USA) NASD Healthcare 65.990 NA NA 1.86 4.96 NA 35.510 33.000 1.02 0.030 7.07 0 NA 0.01 11.71

Biotechnology & Drugs PGNX Progenics Pharmaceuticals, Inc. NASD Healthcare 505.360 NA NA 23.71 7.26 NA 21.310 17.500 74.98 4.700 17.89 -11 NA NA 8.48

Biotechnology & Drugs PRW Pro-Pharmaceuticals, Inc. AMEX Healthcare 78.120 NA NA 2.86 11.17 NA 27.320 22.300 2.32 -0.270 18.36 0 NA NA 8.54

Biotechnology & Drugs PDLI Protein Design Labs, Inc. NASD Healthcare 2,998.920 NA 40.00 28.00 6.26 NA 107.100 104.000 93.39 14.720 2.90 -46 NA 1.06 3.35

Biotechnology & Drugs PPTI Protein Polymer Technologies, Inc. OTC Healthcare 26.230 NA NA 0.39 NA NA 67.260 34.900 0.02 0.010 48.11 0 NA 0.00 9.55

Biotechnology & Drugs PPMD Protide Pharmaceuticals OTC Healthcare 1.130 NA NA 0.28 4.75 NA 4.030 3.400 NA NA 15.61 NA NA 0.30 2.61

Biotechnology & Drugs PVCT Provectus Pharmaceuticals, Inc. OTC Healthcare 15.380 NA NA 0.90 1.69 NA 17.090 11.300 0.15 0.030 33.86 0 NA 0.22 0.48

Biotechnology & Drugs PSDV pSivida Limited (ADR) NASD Healthcare 143.430 NA NA 6.54 2.35 NA 21.930 21.050 0.37 0.060 4.02 0 NA NA 6.80

Biotechnology & Drugs PMD Psychemedics Corp. AMEX Healthcare 70.270 NA NA 13.60 8.75 20.03 5.170 5.000 32.24 0.080 3.23 -2 2.94 NA 4.38

Biotechnology & Drugs QLTI QLT Inc. (USA) NASD Healthcare 710.480 0.66 17.50 7.67 0.81 NA 92.630 92.000 56.15 1.130 0.68 6 NA 0.20 12.28

Biotechnology & Drugs QSC Questcor Pharmaceuticals AMEX Healthcare 28.510 NA NA 0.54 6.00 NA 52.790 44.300 8.64 -0.090 16.09 2 NA 0.13 1.75

Biotechnology & Drugs REGN Regeneron Pharmaceuticals, Inc. NASD Healthcare 532.640 NA NA 9.49 3.23 NA 56.130 36.000 50.83 1.850 35.86 -3 NA 1.21 12.00

Biotechnology & Drugs RGN RegeneRx Biopharmaceut. AMEX Healthcare 130.860 NA NA 3.48 24.00 NA 37.600 30.400 0.67 -0.800 19.16 4 NA NA 19.58

Biotechnology & Drugs RNVS Renovis, Inc. NASD Healthcare 336.500 NA NA 13.53 5.01 NA 24.870 19.400 56.55 4.820 21.99 -29 NA 0.06 9.29

Biotechnology & Drugs RGEN Repligen Corporation NASD Healthcare 93.890 NA NA 3.12 3.55 NA 30.090 28.400 14.26 0.830 5.63 -6 NA NA 8.76

Biotechnology & Drugs RIGL Rigel Pharmaceuticals, Inc. NASD Healthcare 573.920 NA NA 23.77 13.87 NA 24.140 22.000 64.73 -0.140 8.88 -6 NA 0.07 4.11

Biotechnology & Drugs STCX SalesTactix, Inc. OTC Healthcare 0.380 NA NA 0.06 NA NA 6.840 2.300 NA NA 66.36 NA NA NA NA

Biotechnology & Drugs SLXP Salix Pharmaceuticals Ltd NASD Healthcare 782.760 0.91 36.00 21.25 8.06 42.44 36.840 35.400 95.00 3.230 3.90 0 NA 0.00 4.71

Biotechnology & Drugs LIV Samaritan Pharmaceuticals, Inc. AMEX Healthcare 70.570 NA NA 0.52 17.93 NA 135.720 127.400 0.58 0.050 6.13 0 NA NA 10.44

Biotechnology & Drugs SGMO Sangamo Biosciences, Inc. NASD Healthcare 111.580 NA NA 4.39 4.30 NA 25.420 10.800 32.31 -0.080 57.51 0 NA NA 19.02

Biotechnology & Drugs SGNCE Sanguine Corporation OTC Healthcare 8.800 NA NA 0.11 27.50 4.33 80.010 39.200 NA NA 51.01 NA NA NA 9.66

Biotechnology & Drugs SNY sanofi-aventis (ADR) NYSE Healthcare 110,950.020 1.24 11.70 41.55 2.08 NA 2,670.280 1,900.000 6.84 59.680 28.85 0 1.84 0.34 0.81

Biotechnology & Drugs SNTS Santarus, Inc. NASD Healthcare 228.250 -0.10 30.00 6.21 4.15 NA 36.750 33.500 30.80 -5.220 8.86 3 NA 0.00 4.20

Biotechnology & Drugs SVNTE Savient Pharmaceuticals, Inc. NASD Healthcare 229.130 NA NA 3.77 1.54 NA 60.780 57.400 54.58 7.620 5.56 6 NA 0.00 2.38

Biotechnology & Drugs SCLN SciClone Pharmaceuticals NASD Healthcare 257.800 NA NA 5.64 4.80 NA 45.710 44.600 16.30 -3.480 2.43 47 NA 0.11 5.29

Biotechnology & Drugs DDD SCOLR Pharma Inc. AMEX Healthcare 147.740 NA NA 4.24 7.50 NA 34.840 32.100 8.59 0.740 7.88 3 NA 0.00 29.24

Biotechnology & Drugs SGEN Seattle Genetics, Inc. NASD Healthcare 222.110 NA NA 5.25 2.51 NA 42.310 28.300 54.20 1.830 33.11 22 NA NA 3.77

Biotechnology & Drugs STLT Select Therapeutics Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 17.560 15.000 NA NA 14.58 NA NA NA NA

Biotechnology & Drugs SNT Senesco Technologies, Inc. AMEX Healthcare 25.680 NA NA 1.66 4.60 NA 15.470 13.600 10.24 -0.360 12.07 5 NA NA 10.19

Biotechnology & Drugs SNTKY Senetek PLC (ADR) OTC Healthcare 14.330 NA NA 0.24 NA NA 60.960 60.900 0.05 0.020 0.10 0 NA NA 2.72

Biotechnology & Drugs SNMX Senomyx Inc. NASD Healthcare 434.380 NA NA 17.03 13.21 NA 25.510 21.200 69.20 1.770 16.89 -21 NA NA 10.24

Biotechnology & Drugs SGHL Sentigen Holding Corp. NASD Healthcare 35.880 NA NA 4.80 2.60 NA 7.470 5.000 1.38 0.020 33.11 -5 NA 0.06 6.62

Biotechnology & Drugs SEPR Sepracor Inc. NASD Healthcare 6,215.660 NA NA 58.99 NA NA 105.370 97.200 95.00 3.720 7.75 -16 NA NA 4.40

Biotechnology & Drugs SQNM Sequenom, Inc. NASD Healthcare 38.710 NA NA 0.96 1.57 NA 40.320 39.000 10.53 0.010 3.28 0 NA 0.25 2.12

Biotechnology & Drugs SRLS SeraCare Life Sciences NASD Healthcare 238.880 1.27 20.00 17.76 2.63 27.24 13.450 11.400 37.81 3.260 15.24 -3 NA 0.23 4.73

Biotechnology & Drugs SERO Serologicals Corporation NASD Healthcare 789.170 1.36 17.67 22.56 2.03 45.08 34.980 34.500 NA NA 1.38 -16 NA 0.31 4.66

Biotechnology & Drugs SRA Serono S.A. (ADR) NYSE Healthcare 9,586.630 1.38 12.95 16.45 5.17 NA 582.770 204.000 1.09 -0.040 65.00 0 2.27 0.34 1.56

Biotechnology & Drugs SFCC SFBC International, Inc. NASD Healthcare 813.630 0.88 25.33 44.39 2.78 31.39 18.330 17.000 85.79 1.540 7.25 -2 NA 0.58 2.67

Biotechnology & Drugs SHPGY Shire Pharmaceuticals Group plc (ADR) NASD Healthcare 6,108.370 1.38 14.51 36.99 2.61 21.22 165.140 159.970 24.96 3.510 3.13 0 0.46 0.01 4.75

Biotechnology & Drugs SIGA SIGA Technologies, Inc. NASD Healthcare 25.920 NA NA 1.06 14.69 NA 24.500 16.800 3.94 -0.360 31.43 0 NA 0.15 0.32

Biotechnology & Drugs SVA Sinovac Biotech Ltd. AMEX Healthcare 179.220 NA NA 4.77 13.21 NA 37.570 15.800 1.12 0.360 57.95 0 NA 0.22 1.27

Biotechnology & Drugs RNAI Sirna Therapeutics, Inc. NASD Healthcare 261.680 NA NA 4.40 8.59 NA 59.470 24.500 32.89 14.500 58.80 19 NA 0.00 6.90

Biotechnology & Drugs SKYE SkyePharma plc (ADR) NASD Healthcare 453.110 NA NA 7.28 4.03 NA 62.240 51.040 0.75 -0.020 18.00 0 NA 1.31 0.78

Biotechnology & Drugs SLXA Solexa, Inc. NASD Healthcare 152.640 NA NA 5.85 5.58 NA 26.090 14.100 8.82 1.100 45.96 18 NA 0.11 0.74

Biotechnology & Drugs SNUS Sonus Pharmaceuticals, Inc. NASD Healthcare 91.030 NA NA 4.25 8.78 NA 21.420 21.100 10.17 -1.450 1.49 0 NA 0.01 5.06

Biotechnology & Drugs DIAGF Spectral Diagnostics, Inc (USA) OTC Healthcare 14.410 NA NA 0.73 4.55 NA 19.860 18.300 0.00 0.000 7.86 0 NA 2.50 2.78





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BioTech Industry 30Sep05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs SPPI Spectrum Pharmaceuticals, Inc. NASD Healthcare 115.880 NA NA 4.96 2.72 NA 23.360 22.800 24.34 -0.250 2.41 6 NA NA 8.38

Biotechnology & Drugs SLXCF Stellar Pharmaceuticals Inc. (USA) OTC Healthcare 23.890 NA NA 1.03 7.52 NA 23.200 17.600 NA NA 24.13 NA NA NA 7.22

Biotechnology & Drugs STEM StemCells, Inc. NASD Healthcare 352.800 NA NA 5.52 10.95 NA 63.910 62.600 12.70 4.230 2.05 0 NA 0.06 13.45

Biotechnology & Drugs STGN Stratagene Corporation NASD Healthcare 199.570 1.72 15.00 9.01 3.31 22.21 22.150 8.800 16.15 0.470 60.27 -6 NA 0.07 2.05

Biotechnology & Drugs SUPG SuperGen, Inc. NASD Healthcare 322.900 NA NA 6.30 4.97 NA 51.250 46.700 40.94 1.220 8.89 -1 NA NA 5.90

Biotechnology & Drugs SWME Swiss Medica, Inc. OTC Healthcare 17.740 NA NA 0.20 6.06 NA 88.720 75.100 0.05 0.010 15.35 2 NA 0.42 1.73

Biotechnology & Drugs SYMBA Symbollon Pharmaceuticals, Inc. OTC Healthcare 6.570 NA NA 0.85 5.09 NA 7.740 6.400 0.00 0.000 17.26 0 NA NA 8.59

Biotechnology & Drugs SBIO Synbiotics Corporation OTC Healthcare 2.710 NA NA 0.08 1.31 NA 33.820 13.900 0.01 -0.240 58.90 0 NA 1.19 1.72

Biotechnology & Drugs SYBD Synthetic Blood Int'l Inc OTC Healthcare 22.430 NA NA 0.18 21.88 NA 128.160 125.600 0.02 0.000 2.00 0 NA NA 2.12

Biotechnology & Drugs TNOX Tanox, Inc. NASD Healthcare 656.660 NA NA 14.65 3.19 NA 44.820 25.000 55.88 0.660 44.22 0 NA 0.02 22.60

Biotechnology & Drugs TPPH Tapestry Pharmaceuticals, Inc. NASD Healthcare 12.670 NA NA 0.37 0.66 NA 34.240 31.100 10.52 -0.240 9.17 0 NA 0.18 9.08

Biotechnology & Drugs TGEN Targeted Genetics Corp. NASD Healthcare 58.230 NA NA 0.68 1.46 NA 85.630 60.100 3.89 -1.110 29.81 -25 NA 0.28 5.76

Biotechnology & Drugs TARO Taro Pharmaceutical Industries Ltd. NASD Healthcare 750.620 0.57 43.02 25.73 1.99 37.45 29.170 26.900 65.50 0.970 7.79 0 NA 0.70 2.36

Biotechnology & Drugs TCPI TCPI, Inc. OTC Healthcare 0.090 NA NA 0.00 0.01 NA 96.910 91.100 0.02 0.020 5.99 0 NA 0.01 0.64

Biotechnology & Drugs TECH Techne Corporation NASD Healthcare 2,214.490 2.38 13.00 56.98 8.22 35.15 38.860 36.300 84.07 0.170 6.60 -11 NA 0.06 9.63

Biotechnology & Drugs TELK Telik, Inc. NASD Healthcare 850.270 -0.18 54.00 16.36 3.73 NA 51.970 51.600 91.39 1.130 0.72 0 NA 0.01 14.14

Biotechnology & Drugs TRCA Tercica, Inc. NASD Healthcare 356.140 NA NA 11.28 3.97 NA 31.570 16.100 33.02 -0.870 49.01 -9 NA NA 9.29

Biotechnology & Drugs TEVA NASD

Teva Pharmaceutical Industries Ltd (ADR) Healthcare 20,189.020 0.93 23.21 33.42 3.80 22.01 604.100 555.800 59.96 49.550 8.00 0 0.80 0.36 2.04

Biotechnology & Drugs IMNR The Immune Response Corp. NASD Healthcare 23.920 NA NA 0.46 NA NA 52.010 29.700 3.24 -0.650 42.89 2 NA NA 0.69

Biotechnology & Drugs MDCO The Medicines Company NASD Healthcare 1,141.290 1.60 39.00 23.01 6.33 84.93 49.600 44.600 95.00 -1.550 10.08 -3 NA NA 5.13

Biotechnology & Drugs QGLY The Quigley Corporation NASD Healthcare 105.230 NA NA 9.02 5.26 NA 11.670 9.100 3.99 0.090 22.00 0 NA 0.08 3.98

Biotechnology & Drugs TGX Theragenics Corporation NYSE Healthcare 94.280 NA NA 2.95 0.66 NA 31.960 31.300 38.56 -1.520 2.06 0 NA NA 15.18

Biotechnology & Drugs THRX Theravance, Inc. NASD Healthcare 1,128.260 NA NA 21.04 8.40 NA 53.620 37.500 35.30 4.770 30.07 0 NA 0.02 5.56

Biotechnology & Drugs TWTI Third Wave Technologies NASD Healthcare 203.250 -0.60 25.00 4.95 3.94 NA 41.060 34.700 56.36 -0.600 15.49 4 NA 0.21 2.96

Biotechnology & Drugs THLD Threshold Pharmaceuticals, Inc. NASD Healthcare 420.100 NA NA 13.65 8.97 NA 30.780 13.800 23.11 -0.170 55.16 -1 NA 0.01 5.16

Biotechnology & Drugs TBV Tiens Biotech Group (USA), Inc. AMEX Healthcare 268.930 NA NA 3.77 3.65 10.62 71.330 4.300 0.06 0.040 93.97 0 NA 0.15 6.03

Biotechnology & Drugs TTP Titan Pharmaceuticals AMEX Healthcare 57.330 NA NA 1.77 2.62 NA 32.390 30.000 19.77 -0.550 7.39 0 NA NA 7.40

Biotechnology & Drugs TRGNY Transgene (ADR) OTC Healthcare 80.750 NA NA 2.65 13.40 NA 30.470 7.270 0.00 0.000 76.13 0 NA NA 1.58

Biotechnology & Drugs TRMS Trimeris, Inc. NASD Healthcare 336.850 NA NA 15.34 14.84 NA 21.960 17.600 91.38 -1.000 19.85 3 NA NA 7.51

Biotechnology & Drugs TRIB Trinity Biotech plc (ADR) NASD Healthcare 104.160 NA NA 7.40 0.86 19.87 14.080 12.630 5.93 0.840 10.31 0 NA 0.15 3.40

Biotechnology & Drugs TMGU Trinity Medical Group USA, Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 19.520 9.900 NA NA 49.28 NA NA NA 0.34

Biotechnology & Drugs TRPS Tripos, Inc. NASD Healthcare 42.480 NA NA 4.20 1.26 26.80 10.110 9.600 40.74 -0.420 5.08 -2 NA 0.49 1.02

Biotechnology & Drugs UGNE Unigene Laboratories OTC Healthcare 238.560 NA NA 2.91 NA NA 81.980 76.900 0.38 -0.160 6.20 0 NA NA 0.22

Biotechnology & Drugs UTHR United Therapeutics Corporation NASD Healthcare 1,592.580 1.17 32.50 69.80 7.34 51.67 22.820 22.300 95.00 2.050 2.26 -69 NA 0.00 8.04

Biotechnology & Drugs UG United-Guardian, Inc. AMEX Healthcare 40.490 NA NA 8.20 3.06 15.83 4.940 2.800 7.84 -0.200 43.30 -1 2.20 NA 17.34

Biotechnology & Drugs VRX Valeant Pharmaceuticals International NYSE Healthcare 1,859.730 1.06 57.25 20.08 3.75 NA 92.620 92.100 95.00 0.590 0.56 2 1.54 1.60 3.44

Biotechnology & Drugs VLTS Valentis, Inc. NASD Healthcare 31.230 NA NA 2.38 3.02 NA 13.120 9.800 39.02 -0.120 25.32 -1 NA NA 4.76

Biotechnology & Drugs VAPH Vaso Active Pharmaceuticals, Inc. OTC Healthcare 6.710 NA NA 0.65 NA NA 10.330 5.700 0.90 0.040 44.82 0 NA NA 1.36

Biotechnology & Drugs VXGN VaxGen, Inc. OTC Healthcare 429.290 NA NA 14.50 13.62 NA 29.610 29.600 20.03 -1.680 0.02 0 NA 0.00 1.47

Biotechnology & Drugs VNLS Vernalis plc (ADR) NASD Healthcare 189.330 NA NA 2.43 8.33 NA 77.850 54.500 0.98 0.030 29.99 0 NA 4.68 3.81

Biotechnology & Drugs VRTX Vertex Pharmaceuticals Incorporated NASD Healthcare 2,138.350 NA NA 22.35 17.33 NA 95.680 92.100 86.22 18.970 3.74 -18 NA 2.75 3.37

Biotechnology & Drugs VIAC Viacell, Inc. NASD Healthcare 220.400 NA 0.00 5.80 3.53 NA 38.000 27.000 15.43 1.710 28.95 -6 NA 0.04 4.82

Biotechnology & Drugs VICL Vical Incorporated NASD Healthcare 115.710 NA NA 4.92 1.64 NA 23.520 23.500 30.43 -0.450 0.08 0 NA 0.13 6.63

Biotechnology & Drugs VION Vion Pharmaceuticals, Inc. NASD Healthcare 143.180 NA NA 2.17 2.52 NA 65.980 64.300 50.99 -2.810 2.55 -1 NA NA 10.47

Biotechnology & Drugs VQPH VioQuest Pharmaceuticals, Inc . OTC Healthcare 18.720 NA NA 1.05 12.50 NA 17.830 9.400 NA NA 47.27 NA NA NA 1.02

Biotechnology & Drugs VGNI Viragen International, Inc. OTC Healthcare 5.890 NA NA 0.08 2.29 NA 73.670 9.600 NA NA 86.97 NA NA 0.28 4.05

Biotechnology & Drugs VRA Viragen, Inc. AMEX Healthcare 18.540 NA NA 0.50 1.09 NA 37.090 36.300 5.98 0.010 2.13 3 NA 0.94 0.96

Biotechnology & Drugs VRAL Viral Genetics, Inc. OTC Healthcare 19.450 NA NA 0.21 5.83 NA 92.620 35.200 0.06 0.000 62.00 0 NA 0.58 0.11

Biotechnology & Drugs VBAC Virbac Corporation OTC Healthcare 73.670 NA NA 3.30 4.16 51.79 22.330 8.300 2.87 0.020 62.82 0 NA 1.32 0.90

Biotechnology & Drugs VPHM ViroPharma Incorporated NASD Healthcare 1,203.470 1.33 17.67 20.80 21.09 37.16 57.860 55.600 41.83 11.330 3.90 26 NA 2.00 2.65

Biotechnology & Drugs PRH VitaCube Systems Holdings, Inc. AMEX Healthcare 15.340 NA NA 1.60 2.48 NA 9.590 5.300 NA NA 44.73 NA NA NA 16.49

Biotechnology & Drugs VTLV Vital Living, Inc. OTC Healthcare 4.400 NA NA 0.04 0.23 NA 104.810 83.800 0.78 0.000 20.04 0 NA 0.15 0.30

Biotechnology & Drugs VVUS VIVUS, Inc. NASD Healthcare 159.850 NA NA 3.59 4.81 NA 44.530 43.200 42.74 1.390 2.98 3 NA 0.13 3.26

Biotechnology & Drugs VYRX Vyrex Corporation OTC Healthcare 0.930 NA NA 0.11 NA NA 8.490 7.300 NA NA 14.05 NA NA NA 0.14

Biotechnology & Drugs WPI Watson Pharmaceuticals, Inc. NYSE Healthcare 3,471.730 2.78 9.59 36.61 1.88 30.23 94.830 90.500 82.41 -2.290 4.57 -11 NA 0.27 5.50

Biotechnology & Drugs WFHCQ Women First HealthCare OTC Healthcare 0.010 NA NA 0.00 NA NA 26.660 16.000 0.00 0.000 39.98 0 NA NA 0.16

Biotechnology & Drugs XCYT Xcyte Therapies, Inc. NASD Healthcare 9.440 NA NA 0.48 0.30 NA 19.670 14.400 15.88 -3.160 26.80 0 NA 0.14 5.70

Biotechnology & Drugs XKEM Xechem International, Inc OTC Healthcare 3.380 NA NA 0.01 NA NA 259.690 248.200 0.19 0.000 4.42 0 NA NA 0.08

Biotechnology & Drugs XNPT XenoPort, Inc. NASD Healthcare 325.670 NA NA 16.50 3.74 NA 19.740 5.000 26.14 5.160 74.67 4 NA 0.02 11.44

Biotechnology & Drugs XNVAY Xenova Group plc (ADR) OTC Healthcare 12.950 NA NA 0.30 0.24 NA 43.150 36.250 0.70 -1.020 16.00 0 NA NA 2.07

Biotechnology & Drugs XOMA XOMA Limited NASD Healthcare 151.850 NA NA 1.76 NA NA 86.280 76.900 19.76 -4.970 10.87 -1 NA NA 5.17

Biotechnology & Drugs XTRN Xtrana, Inc. OTC Healthcare 3.640 NA NA 0.22 1.77 NA 16.530 14.200 0.01 0.000 14.11 0 NA NA 19.31

Biotechnology & Drugs YMI YM BioSciences Inc. (USA) AMEX Healthcare 105.450 NA NA 3.00 3.50 NA 35.150 34.400 18.61 1.200 2.14 0 NA NA 8.02

Biotechnology & Drugs ZILA Zila, Inc. NASD Healthcare 159.910 -0.61 32.50 3.49 3.76 NA 45.820 45.400 24.28 -2.140 0.92 0 NA 0.09 2.27

Biotechnology & Drugs ZONA Zonagen, Incorporated NASD Healthcare 57.960 NA NA 5.75 2.75 NA 10.080 9.900 29.69 -0.400 1.79 2 NA NA 29.24





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 30Sep05 17 of 45 10/24/2011 3:30 PM

BioTech Industry 30Sep05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs ZMTX ZymeTx, Inc. OTC Healthcare 0.390 NA NA 0.05 NA NA 8.610 6.600 0.00 0.000 23.31 0 NA NA 0.20

Biotechnology & Drugs ZGEN ZymoGenetics, Inc. NASD Healthcare 957.210 -0.73 15.00 16.50 3.98 NA 58.010 29.300 27.88 0.330 49.49 -6 NA NA 9.32

Major Drugs ABT Abbott Laboratories NYSE Healthcare 65,907.230 1.72 9.91 42.40 4.58 19.05 1,554.420 1,451.400 63.19 10.790 6.63 1 2.59 0.40 1.59

Major Drugs ARXT Adams Respiratory Therapeutics, Inc. NASD Healthcare 1,072.040 1.10 25.32 32.29 NA NA 33.200 32.900 0.44 0.040 0.90 7 NA NA 2.75

Major Drugs ACL Alcon, Inc. NYSE Healthcare 39,650.770 1.99 18.59 127.88 17.00 41.62 310.060 74.400 22.45 2.050 76.00 0 0.77 0.50 1.38

Major Drugs ALLI Allion Healthcare, Inc. NASD Healthcare 226.780 12.86 17.50 18.01 3.70 NA 12.590 12.590 22.21 2.800 0.00 0 NA 0.04 3.43

Major Drugs APNS Applied Neurosolutions, Inc. OTC Healthcare 36.480 NA NA 0.39 14.44 NA 93.540 85.500 11.85 4.790 8.60 -13 NA 0.00 5.40

Major Drugs AZN AstraZeneca PLC (ADR) NYSE Healthcare 77,479.500 1.11 15.07 47.10 5.69 17.50 1,645.000 1,628.600 8.54 8.440 1.00 0 1.61 0.10 1.98

Major Drugs BAY Bayer AG (ADR) NYSE Healthcare 26,876.520 1.93 7.00 36.80 1.92 20.19 730.340 723.000 3.91 0.720 1.01 0 1.92 0.72 1.71

Major Drugs BMY Bristol Myers Squibb Co. NYSE Healthcare 47,058.040 4.14 4.05 24.06 4.36 19.62 1,955.860 1,942.000 68.09 25.350 0.71 -1 4.66 0.58 1.41

Major Drugs LLY Eli Lilly & Co. NYSE Healthcare 60,681.730 1.88 10.09 53.52 5.91 47.13 1,133.810 978.900 70.21 21.160 13.66 -66 2.84 0.46 1.70

Major Drugs GSK GlaxoSmithKline plc (ADR) NYSE Healthcare 145,973.780 2.15 8.38 51.28 12.57 18.93 2,846.610 2,448.100 9.62 3.780 14.00 0 2.71 1.06 1.46

Major Drugs JNJ Johnson & Johnson NYSE Healthcare 188,238.640 1.65 11.10 63.28 5.35 20.83 2,974.690 2,944.900 65.04 9.440 1.00 -2 2.09 0.08 2.47

Major Drugs MRK Merck & Co., Inc. NYSE Healthcare 59,741.810 -3.30 -3.32 27.21 3.44 13.35 2,195.580 2,173.600 61.72 19.170 1.00 -1 5.59 0.41 1.71

Major Drugs NVD Novadel Pharma Inc AMEX Healthcare 70.990 NA NA 1.75 16.36 NA 40.570 26.000 6.70 -0.030 35.91 3 NA 0.00 2.05

Major Drugs NVS Novartis AG (ADR) NYSE Healthcare 118,804.500 1.61 11.63 51.00 3.91 25.30 2,329.500 2,300.000 8.70 17.500 1.27 0 1.73 0.25 1.59

Major Drugs PFE Pfizer Inc. NYSE Healthcare 184,041.420 1.39 9.05 24.97 2.83 18.89 7,370.500 7,309.900 62.72 80.780 0.82 -8 3.04 0.20 1.49

Major Drugs PBH Prestige Brands Holdings, Inc. NYSE Healthcare 616.660 1.36 11.50 12.32 1.58 100.42 50.050 33.000 60.82 2.590 34.07 4 NA 1.27 2.58

Major Drugs RHHBY Roche Holding Ltd. (ADR) OTC Healthcare 120,932.030 2.00 14.29 70.10 4.88 23.53 1,725.130 1,382.400 0.27 1.240 19.87 0 NA 0.25 3.90

Major Drugs SHR Schering AG (ADR) NYSE Healthcare 12,045.970 1.44 12.10 63.40 3.25 17.79 190.000 24.700 3.64 0.440 87.00 0 2.02 0.08 2.53

Major Drugs SGP Schering-Plough Corp. NYSE Healthcare 31,077.770 2.97 20.90 21.05 5.27 NA 1,476.380 1,432.800 75.24 -0.460 2.95 -3 1.05 0.38 2.14

Major Drugs SNSS Sunesis Pharmaceuticals, Inc. NASD Healthcare 143.540 NA NA 6.69 NA NA 21.460 6.000 NA NA 72.04 NA NA 0.20 3.02

Major Drugs WYE Wyeth NYSE Healthcare 62,056.200 2.18 7.30 46.27 5.77 36.94 1,341.180 1,334.100 74.04 4.370 0.53 -4 2.16 0.74 1.55









492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 30Sep05 18 of 45 10/24/2011 3:30 PM

BioTech Industry 08Jul05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs APPA A.P. Pharma, Inc. NASD Healthcare 39.790 NA NA 1.58 3.07 NA 25.180 24.200 38.63 -0.550 3.90 0 NA NA 6.91

Biotechnology & Drugs AAIIQ aaiPharma Inc. OTC Healthcare 7.860 NA NA 0.28 NA NA 28.590 23.000 20.13 -2.280 19.54 -1 NA NA 0.13

Biotechnology & Drugs ASTM Aastrom Biosciences, Inc. NASD Healthcare 331.810 NA NA 3.26 9.17 NA 101.780 96.600 7.42 1.440 5.09 0 NA NA 45.43

Biotechnology & Drugs ABAX Abaxis, Inc. NASD Healthcare 221.900 2.38 20.00 11.15 3.60 49.56 19.900 19.300 50.68 -0.900 3.02 1 NA 0.00 6.02

Biotechnology & Drugs ABGX Abgenix, Inc. NASD Healthcare 858.510 -0.31 15.00 9.57 4.76 NA 89.710 79.400 83.74 1.360 11.49 1 NA 2.02 13.27

Biotechnology & Drugs ABRX Able Laboratories Inc. NASD Healthcare 53.330 NA NA 2.88 0.52 3.24 18.520 17.700 84.63 0.730 4.41 -2 NA 0.00 6.81

Biotechnology & Drugs ACAD ACADIA Pharmaceuticals Inc. NASD Healthcare 210.160 NA NA 9.00 5.02 NA 23.350 17.300 23.21 0.020 25.91 3 NA 0.05 3.73

Biotechnology & Drugs ACAM Acambis plc (ADR) NASD Healthcare 451.070 NA NA 8.54 2.53 15.96 52.820 45.400 2.80 -0.310 14.05 0 NA 0.06 3.58

Biotechnology & Drugs ACCL Accelrys, Inc. NASD Healthcare 135.550 NA NA 5.19 1.44 NA 26.120 24.300 58.59 -1.670 6.96 0 NA NA 1.53

Biotechnology & Drugs AKC Access Pharmaceuticals AMEX Healthcare 25.630 NA NA 1.63 NA NA 15.720 14.000 25.75 -0.070 10.97 0 NA NA 0.35

Biotechnology & Drugs AGNM Acrongenomics Inc. OTC Healthcare 73.220 NA NA 4.65 9.82 NA 15.750 7.900 0.01 0.000 49.83 0 NA 0.02 0.09

Biotechnology & Drugs ACUR Acura Pharmaceuticals, Inc. OTC Healthcare 14.110 NA NA 0.62 NA NA 22.950 19.700 0.62 0.000 14.15 0 NA NA 1.99

Biotechnology & Drugs ACUS Acusphere, Inc. NASD Healthcare 97.900 NA NA 5.49 1.28 NA 17.830 16.400 47.83 0.590 8.03 -19 NA 0.22 5.24

Biotechnology & Drugs ADZA Adeza Biomedical Corporation NASD Healthcare 265.660 1.23 35.00 15.90 3.16 23.45 16.710 11.000 45.56 0.070 34.16 0 NA 0.00 16.40

Biotechnology & Drugs ADH Adherex Technologies Inc. (USA) AMEX Healthcare 63.940 NA NA 0.35 NA NA 182.680 154.100 8.38 0.040 15.64 0 NA NA NA

Biotechnology & Drugs ADLR Adolor Corporation NASD Healthcare 389.700 NA NA 9.97 3.51 NA 39.090 37.700 77.74 1.420 3.55 2 NA NA 9.75

Biotechnology & Drugs AVM Advanced Magnetics, Inc. AMEX Healthcare 108.350 NA NA 11.00 7.36 NA 9.850 8.600 29.65 -0.040 12.69 1 NA NA 4.62

Biotechnology & Drugs APPI Advanced Plant Pharmaceuticals Inc. OTC Healthcare 3.030 NA NA 0.00 NA NA 777.380 738.500 0.00 0.000 5.00 0 NA NA 0.00

Biotechnology & Drugs ATISZ Advanced Tissue Sciences OTC Healthcare 3.730 NA NA 0.05 0.26 NA 73.150 47.600 1.53 0.360 34.93 0 NA 0.31 1.21

Biotechnology & Drugs ADVR Advanced Viral Research OTC Healthcare 66.860 NA NA 0.10 7.53 NA 696.490 647.700 0.07 0.240 7.01 2 NA 0.00 24.14

Biotechnology & Drugs AVNC Advancis Pharmaceutical Corporation NASD Healthcare 46.330 -0.04 30.00 1.56 1.23 NA 29.700 7.700 14.78 0.260 74.07 2 NA 0.08 1.88

Biotechnology & Drugs ANX ADVENTRX Pharmaceuticals, Inc. AMEX Healthcare 119.560 NA NA 2.18 12.02 NA 54.840 45.000 7.24 -0.270 17.95 6 NA NA 9.14

Biotechnology & Drugs AOLS Aeolus Pharmaceuticals, Inc. OTC Healthcare 13.420 NA NA 0.96 6.86 NA 13.980 5.600 5.73 -0.200 59.93 5 NA 0.42 3.81

Biotechnology & Drugs AEZS AEterna Zentaris Inc. (USA) NASD Healthcare 209.010 NA NA 4.53 2.11 NA 46.140 42.400 2.59 -0.410 8.11 0 NA 0.87 2.30

Biotechnology & Drugs AEMD Aethlon Medical, Inc. OTC Healthcare 3.530 NA NA 0.22 NA NA 16.050 11.900 NA NA 25.84 NA NA NA 0.02

Biotechnology & Drugs AFFX Affymetrix, Inc. NASD Healthcare 3,737.560 1.89 26.60 59.25 12.56 59.73 63.080 62.900 95.00 0.050 0.29 -30 NA 0.41 4.07

Biotechnology & Drugs AKES Akesis Pharmaceuticals Inc OTC Healthcare 123.690 NA NA 8.25 146.38 NA 14.990 6.100 NA NA 59.31 NA NA NA 9.19

Biotechnology & Drugs AKN Akorn, Inc. AMEX Healthcare 76.380 NA NA 2.94 12.29 NA 25.980 10.500 22.33 0.460 59.58 0 NA 0.23 2.36

Biotechnology & Drugs AMRI Albany Molecular Research NASD Healthcare 475.980 1.64 15.00 14.75 1.58 NA 32.270 27.400 57.65 0.990 15.09 17 NA 0.17 4.17

Biotechnology & Drugs ALXN Alexion Pharmaceuticals, Inc. NASD Healthcare 704.280 NA NA 25.05 7.14 NA 28.110 27.200 95.00 0.720 3.25 -9 NA 1.53 8.80

Biotechnology & Drugs ACEL Alfacell Corporation NASD Healthcare 76.560 NA NA 2.10 15.85 NA 36.460 35.800 8.74 -0.230 1.80 1 NA 0.04 3.68

Biotechnology & Drugs ALKS Alkermes, Inc. NASD Healthcare 1,310.870 -1.74 14.70 14.50 318.71 NA 90.400 86.700 91.31 2.480 4.10 0 NA 74.81 9.62

Biotechnology & Drugs AGN Allergan, Inc. NYSE Healthcare 11,236.720 1.52 17.33 86.15 10.26 30.42 130.430 127.800 92.63 3.640 2.02 0 0.46 0.53 2.97

Biotechnology & Drugs ALLP Alliance Pharmaceutical Corp. OTC Healthcare 5.460 NA NA 0.16 NA NA 34.120 31.700 1.08 0.050 7.09 0 NA NA 0.50

Biotechnology & Drugs ALTH Allos Therapeutics, Inc. NASD Healthcare 64.850 NA NA 2.08 3.45 NA 31.180 30.600 33.21 1.310 1.85 4 NA NA 15.55

Biotechnology & Drugs ALNY Alnylam Pharmaceuticals, Inc. NASD Healthcare 149.150 NA NA 7.13 3.74 NA 20.920 16.200 9.90 -0.940 22.56 -14 NA 0.20 6.75

Biotechnology & Drugs ALO Alpharma Inc. NYSE Healthcare 804.760 2.17 12.13 15.17 0.94 NA 53.050 40.500 83.61 3.990 23.66 0 1.19 0.68 1.07

Biotechnology & Drugs AAA Altana AG(ADR) NYSE Healthcare 6,831.880 NA NA 50.50 3.25 14.65 135.290 67.600 1.55 0.720 50.03 0 2.41 0.04 NA

Biotechnology & Drugs ALT Alteon Inc. AMEX Healthcare 13.340 NA NA 0.23 0.95 NA 58.000 53.400 20.24 2.170 7.93 0 NA NA 7.25

Biotechnology & Drugs AMAR Amarillo Biosciences, Inc OTC Healthcare 5.610 NA NA 0.35 NA NA 16.020 11.900 0.09 0.000 25.72 0 NA NA 0.01

Biotechnology & Drugs AMRN Amarin Corporation plc (ADR) NASD Healthcare 50.240 NA NA 1.33 2.13 NA 37.770 16.600 0.06 -0.010 56.05 0 NA NA 1.82

Biotechnology & Drugs MABAA American Biogenetic Sciences, Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 44.950 34.500 NA NA 23.25 NA NA NA 0.06

Biotechnology & Drugs AOBO American Oriental Bioengineering, Inc. OTC Healthcare 70.750 NA NA 1.78 2.00 7.33 39.750 13.500 NA NA 66.04 NA NA 0.14 2.68

Biotechnology & Drugs APPX American Pharmaceutical Partners, Inc. NASD Healthcare 2,917.030 0.87 27.63 40.58 8.33 43.03 71.880 20.700 27.21 1.570 71.20 1 NA NA 3.75

Biotechnology & Drugs ABC AmerisourceBergen Corp. NYSE Healthcare 7,387.330 1.76 12.30 70.89 1.78 20.68 104.210 103.100 95.00 1.200 1.06 -5 0.14 0.23 1.26

Biotechnology & Drugs AMGN Amgen, Inc. NASD Healthcare 85,547.040 1.32 17.57 69.13 4.49 35.65 1,237.480 1,229.100 68.65 5.510 0.68 -12 NA 0.21 1.55

Biotechnology & Drugs AMLN Amylin Pharmaceuticals NASD Healthcare 2,266.190 NA NA 21.74 35.19 NA 104.240 99.200 83.84 9.690 4.84 -11 NA 5.96 10.74

Biotechnology & Drugs ANDS Anadys Pharmaceuticals, Inc. NASD Healthcare 244.650 NA NA 10.94 10.38 NA 22.360 19.400 32.02 0.660 13.25 -5 NA 0.09 3.51

Biotechnology & Drugs ADRX Andrx Corporation NASD Healthcare 1,513.470 1.17 17.79 20.68 2.05 20.46 73.180 71.500 81.25 3.330 2.30 0 NA NA 3.16

Biotechnology & Drugs ANPI Angiotech Pharmaceuticals, Inc. (USA) NASD Healthcare 1,176.730 0.67 22.00 13.99 2.55 15.74 84.110 79.100 49.07 -6.970 5.96 0 NA NA 15.13

Biotechnology & Drugs ANIK Anika Therapeutics, Inc. NASD Healthcare 112.640 NA NA 10.92 3.53 26.96 10.310 9.600 38.05 -0.340 6.93 -14 NA NA 7.96

Biotechnology & Drugs ANXB Antex Biologics, Inc. OTC Healthcare 0.010 NA NA 0.00 NA NA 12.410 10.300 NA NA 16.99 NA NA NA 0.79

Biotechnology & Drugs AGEN Antigenics, Inc. NASD Healthcare 274.300 NA NA 6.02 3.11 NA 45.560 24.300 17.61 -2.930 46.67 0 NA 0.66 6.83

Biotechnology & Drugs APHT Aphton Corporation NASD Healthcare 41.160 NA NA 0.69 5.32 NA 59.650 58.000 32.26 4.070 2.77 2 NA 1.78 3.11

Biotechnology & Drugs ARNA Arena Pharmaceuticals NASD Healthcare 250.310 NA NA 7.10 1.67 NA 35.260 32.400 66.78 6.470 8.10 0 NA NA 3.17

Biotechnology & Drugs AGNT Argonaut Technologies, Inc OTC Healthcare 20.360 NA NA 0.98 0.62 NA 20.770 20.300 33.21 -1.390 2.28 -24 NA 0.00 5.64

Biotechnology & Drugs ARIA Ariad Pharmaceuticals, Inc. NASD Healthcare 378.070 -0.73 10.00 7.15 6.81 NA 52.880 49.000 41.03 -0.130 7.33 0 NA 0.16 6.26

Biotechnology & Drugs ARQL ArQule, Inc. NASD Healthcare 229.770 -3.15 3.00 6.60 2.10 NA 34.810 34.100 48.62 5.710 2.05 3 NA 0.00 5.64

Biotechnology & Drugs ARRY Array BioPharma Inc. NASD Healthcare 259.400 -0.19 50.00 6.76 2.43 NA 38.370 33.100 72.37 0.120 13.74 -1 NA NA 4.80

Biotechnology & Drugs ASPV Aspreva Pharmaceuticals Corporation NASD Healthcare 491.030 -5.12 15.00 14.43 4.57 NA 34.030 7.200 7.54 2.570 78.84 7 NA 0.01 16.63

Biotechnology & Drugs ASTR Astralis, Ltd. OTC Healthcare 14.650 NA NA 0.20 18.67 NA 73.270 19.300 0.82 0.000 73.66 0 NA NA 1.67

Biotechnology & Drugs AGIX AtheroGenics, Inc. NASD Healthcare 608.890 NA NA 16.15 NA NA 37.700 36.200 95.00 1.500 3.98 11 NA NA 28.87

Biotechnology & Drugs AIMM AutoImmune Inc. OTC Healthcare 16.410 NA NA 0.97 1.68 NA 16.920 16.800 30.41 0.030 0.71 0 NA NA 95.72

Biotechnology & Drugs AUXL Auxilium Pharmaceuticals, Inc. NASD Healthcare 117.900 -0.10 30.00 5.70 4.75 NA 20.680 15.100 90.43 1.190 26.99 1 NA 0.02 2.67

Biotechnology & Drugs AVN AVANIR Pharmaceuticals AMEX Healthcare 319.440 NA NA 2.97 190.10 NA 107.560 97.600 30.96 4.630 9.26 1 NA 0.65 1.82







492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 08Jul05 19 of 45 10/24/2011 3:30 PM

BioTech Industry 08Jul05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs AVAN AVANT Immunotherapeutics, Inc. NASD Healthcare 101.560 NA NA 1.37 3.02 NA 74.130 73.700 19.04 -1.040 0.58 0 NA 0.06 6.28

Biotechnology & Drugs AVXT AVAX Technologies, Inc. OTC Healthcare 18.700 NA NA 0.30 15.47 NA 62.550 61.400 3.71 0.050 1.83 0 NA 0.51 0.79

Biotechnology & Drugs AVII AVI BioPharma, Inc. NASD Healthcare 99.780 NA NA 2.26 2.30 NA 44.150 37.700 10.48 0.260 14.61 0 NA NA 16.45

Biotechnology & Drugs AVGN Avigen, Inc. NASD Healthcare 69.090 NA NA 3.39 0.93 NA 20.380 20.300 44.32 0.420 0.40 0 NA 0.11 37.84

Biotechnology & Drugs AXCA Axcan Pharma Inc. (USA) NASD Healthcare 703.920 1.49 15.00 15.43 1.71 19.78 45.620 42.000 42.47 -1.250 7.94 0 NA 0.31 3.05

Biotechnology & Drugs AXJ AXM Pharma, Inc. AMEX Healthcare 25.590 NA NA 1.31 4.91 NA 19.540 11.400 5.16 0.540 41.65 0 NA 0.59 0.48

Biotechnology & Drugs AXYX Axonyx Inc. NASD Healthcare 71.910 NA NA 1.34 0.94 NA 53.670 51.900 24.50 -13.840 3.29 3 NA 0.00 12.02

Biotechnology & Drugs BRL Barr Pharmaceuticals, Inc. NYSE Healthcare 5,077.220 1.28 16.13 49.17 4.29 27.84 103.260 98.100 75.93 1.470 5.00 -15 NA 0.02 4.69

Biotechnology & Drugs BTRX Barrier Therapeutics, Inc. NASD Healthcare 192.210 -0.12 30.00 8.02 1.78 15.19 23.970 14.900 66.24 2.650 37.83 -5 NA 0.01 11.63

Biotechnology & Drugs BGCC Beluga Composites Corp. OTC Healthcare 0.050 NA NA 1.50 NA NA 0.030 0.010 NA NA 77.14 NA NA 0.02 2.46

Biotechnology & Drugs BNT Bentley Pharmaceuticals, Inc. NYSE Healthcare 246.690 0.96 32.00 11.57 2.78 37.08 21.320 19.100 39.80 0.180 10.42 1 NA 0.03 2.61

Biotechnology & Drugs BASI Bioanalytical Systems, Inc. NASD Healthcare 31.710 NA NA 6.51 1.65 NA 4.870 3.200 12.91 0.290 34.31 0 NA 0.80 1.51

Biotechnology & Drugs BCRX BioCryst Pharmaceuticals, Inc. NASD Healthcare 138.070 NA NA 5.28 2.97 NA 26.150 16.500 36.56 1.090 36.90 0 NA NA 15.55

Biotechnology & Drugs BDSI BioDelivery Sciences International Inc NASD Healthcare 21.040 NA NA 2.89 47.70 NA 7.270 1.600 0.99 0.000 77.99 0 NA 0.28 0.82

Biotechnology & Drugs BIVN Bioenvision, Inc. NASD Healthcare 327.640 NA NA 8.10 4.23 NA 40.450 40.400 43.40 4.410 0.12 0 NA NA 14.03

Biotechnology & Drugs BIIB Biogen Idec Inc NASD Healthcare 12,210.160 1.49 15.72 35.43 1.80 112.83 344.630 343.300 75.81 -15.250 0.39 -11 NA 0.13 1.62

Biotechnology & Drugs BMRN BioMarin Pharmaceutical NASD Healthcare 491.880 NA NA 7.61 NA NA 64.640 63.200 69.96 -1.030 2.22 0 NA NA 1.06

Biotechnology & Drugs BIOM Biomira Inc. (USA) NASD Healthcare 134.000 NA NA 1.71 4.98 NA 78.360 77.600 4.27 -0.800 0.97 0 NA 0.01 16.80

Biotechnology & Drugs BNTK Bionet Technologies, Inc. OTC Healthcare 0.000 NA NA 0.00 48.42 NA 13.810 8.700 NA NA 37.02 NA NA NA 0.90

Biotechnology & Drugs BNRX Bionutrics, Inc. OTC Healthcare 11.440 NA NA 0.51 0.98 NA 22.440 6.400 NA NA 71.48 NA NA 0.12 0.12

Biotechnology & Drugs BPRG BioProgress PLC (USA) NASD Healthcare 70.030 NA NA 6.19 1.49 NA 11.310 10.750 0.20 0.020 4.99 0 NA NA 2.83

Biotechnology & Drugs BIOP BioPulse International OTC Healthcare 0.030 NA NA 0.00 NA NA 15.450 7.600 NA NA 50.81 NA NA NA 0.04

Biotechnology & Drugs BPUR Biopure Corporation NASD Healthcare 35.080 NA NA 1.44 0.68 NA 24.360 24.300 NA NA 0.25 NA NA NA 8.10

Biotechnology & Drugs BPA BioSante Pharmaceuticals, Inc. AMEX Healthcare 79.540 NA NA 4.10 5.93 NA 19.400 17.200 28.00 0.460 11.34 -11 NA NA 8.26

Biotechnology & Drugs BSTE Biosite Incorporated NASD Healthcare 960.620 1.23 16.17 56.86 3.87 21.63 16.890 15.400 95.00 -0.450 8.84 -42 NA 0.09 3.77

Biotechnology & Drugs BSOU Bio-Solutions International, Inc. OTC Healthcare 4.420 NA NA 8.50 NA NA 0.520 0.280 NA NA 46.15 NA NA NA 0.08

Biotechnology & Drugs BIOI BioSource International, Inc. NASD Healthcare 107.020 NA NA 11.00 2.73 305.56 9.730 8.200 34.56 0.080 15.72 0 NA NA 3.16

Biotechnology & Drugs BSTC BioSpecifics Technologies Corp. OTC Healthcare 5.860 NA NA 1.10 3.04 NA 5.330 3.000 2.70 0.000 43.67 0 NA 1.03 0.65

Biotechnology & Drugs BIOHF Biotech Holdings Ltd. (USA) OTC Healthcare 29.260 NA NA 0.33 NA NA 90.030 44.100 0.00 0.000 51.02 0 NA NA 0.31

Biotechnology & Drugs BTX BioTime, Inc. AMEX Healthcare 7.150 NA NA 0.40 NA NA 17.870 17.200 1.67 0.010 3.76 0 NA NA 3.08

Biotechnology & Drugs BTRNQ BioTransplant Inc. OTC Healthcare 0.890 NA NA 0.04 0.06 NA 25.390 19.600 0.03 0.000 22.79 0 NA 0.04 2.39

Biotechnology & Drugs BVF Biovail Corporation (USA) NYSE Healthcare 2,473.880 0.57 15.84 15.52 2.34 16.37 159.400 124.300 36.90 0.790 22.02 0 NA 0.44 1.71

Biotechnology & Drugs BLSI Boston Life Sciences, Inc. NASD Healthcare 20.320 NA NA 1.95 4.70 NA 10.420 9.400 4.06 0.420 9.82 0 NA NA 3.05

Biotechnology & Drugs BDY Bradley Pharmaceuticals, Inc. NYSE Healthcare 171.510 0.42 20.00 10.83 1.06 8.88 15.840 13.900 71.11 -1.330 12.23 0 NA 0.67 3.27

Biotechnology & Drugs CADKF Cade Struktur Corporation OTC Healthcare 0.000 NA NA 0.00 2.08 3.48 8.340 7.700 NA NA 7.63 NA NA NA 1.50

Biotechnology & Drugs KDUS Cadus Corporation OTC Healthcare 20.110 NA NA 1.53 0.79 NA 13.140 7.600 2.69 0.100 42.18 3 NA NA 328.12

Biotechnology & Drugs KAL Callisto Pharmaceuticals, Inc. AMEX Healthcare 31.540 NA NA 1.01 6.23 NA 31.230 20.300 5.21 0.240 35.00 9 NA NA 3.71

Biotechnology & Drugs CBM Cambrex Corporation NYSE Healthcare 530.010 1.81 11.67 20.08 1.39 NA 26.400 25.400 89.39 0.830 3.77 -10 0.60 0.62 3.19

Biotechnology & Drugs CATG NASD

Cambridge Antibody Tech. Group plc (ADR) Healthcare 613.640 NA NA 11.89 2.43 NA 51.610 37.300 3.77 0.130 27.73 0 NA NA 4.50

Biotechnology & Drugs CNVX CancerVax Corporation NASD Healthcare 82.060 NA NA 2.95 1.26 NA 27.820 17.200 25.38 0.110 38.17 0 NA 0.16 4.09

Biotechnology & Drugs CPD A

Caraco Pharmaceutical Laboratories Ltd. MEX Healthcare 223.800 0.23 33.00 8.49 NA NA 26.360 9.500 11.07 0.400 63.96 -2 NA NA 2.33

Biotechnology & Drugs CAH Cardinal Health, Inc. NYSE Healthcare 25,010.320 1.46 12.50 58.40 2.89 21.47 428.260 423.300 83.42 2.680 1.16 -15 0.41 0.33 1.37

Biotechnology & Drugs CRME Cardiome Pharma Corp.(USA) NASD Healthcare 310.120 NA NA 6.10 3.57 NA 50.840 49.800 29.11 4.950 2.04 0 NA 0.01 6.09

Biotechnology & Drugs CVBT Cardiovascular Biotherapeutics, Inc. OTC Healthcare 1,216.200 NA NA 10.00 73.40 NA 121.620 1.800 NA NA 98.52 NA NA 0.00 10.42

Biotechnology & Drugs CARN Carrington Laboratories, Inc. NASD Healthcare 48.580 NA NA 4.52 3.64 282.56 10.750 9.500 13.71 0.020 11.59 -1 NA 0.28 1.28

Biotechnology & Drugs CRA Celera Genomics, Applera Corp NYSE Healthcare 839.890 NA NA 11.39 0.99 NA 73.740 72.700 78.30 0.870 1.41 0 NA NA 16.24

Biotechnology & Drugs CELG Celgene Corporation NASD Healthcare 7,077.360 1.66 43.83 42.42 13.22 NA 166.840 163.100 83.97 3.720 2.24 -6 NA 0.75 8.30

Biotechnology & Drugs CEGE Cell Genesys, Inc. NASD Healthcare 269.690 NA NA 5.94 2.44 NA 45.400 45.000 65.47 -1.850 0.89 6 NA 1.78 3.04

Biotechnology & Drugs CTIC Cell Therapeutics, Inc. NASD Healthcare 177.560 NA NA 2.75 NA NA 64.570 62.000 36.83 -15.030 3.98 -2 NA NA 2.92

Biotechnology & Drugs CLGY Cellegy Pharmaceuticals, Inc. NASD Healthcare 46.160 NA NA 1.55 NA NA 29.780 22.900 10.43 0.130 23.11 5 NA NA 0.43

Biotechnology & Drugs CVM CEL-SCI Corporation AMEX Healthcare 36.240 NA NA 0.50 11.61 NA 72.480 65.800 1.29 -0.010 9.21 -10 NA 0.00 11.21

Biotechnology & Drugs CEPH Cephalon, Inc. NASD Healthcare 2,340.220 0.67 21.52 40.32 2.76 NA 58.040 57.500 NA NA 0.93 -6 NA 1.53 5.19

Biotechnology & Drugs CERS Cerus Corporation NASD Healthcare 100.580 NA NA 4.51 2.35 NA 22.300 21.500 33.64 -0.310 3.60 2 NA 0.11 3.98

Biotechnology & Drugs CHTL Chantal Pharmaceutical OTC Healthcare 0.040 NA NA 0.00 0.03 NA 40.810 31.400 NA NA 23.06 NA NA 0.62 0.26

Biotechnology & Drugs CHTT Chattem Inc. NASD Healthcare 889.490 1.78 11.75 44.96 7.32 47.68 19.780 18.300 70.76 0.160 7.50 -13 NA 1.50 3.21

Biotechnology & Drugs CXSP ChemGenex Pharmaceuticals Limited (ADR)NASD Healthcare 90.810 NA NA 7.91 NA NA 11.480 6.770 NA NA 41.03 NA NA NA NA

Biotechnology & Drugs CHIR Chiron Corporation NASD Healthcare 6,789.750 1.65 16.10 36.22 2.67 393.70 187.460 108.300 45.79 9.010 42.23 0 NA 0.43 3.13

Biotechnology & Drugs CNXS CNS, Inc. NASD Healthcare 348.240 1.81 13.33 24.37 4.88 26.12 14.290 11.600 59.22 1.090 18.82 -19 0.99 NA 5.21

Biotechnology & Drugs CLSCE Cobalis Corporation OTC Healthcare 12.640 NA NA 0.54 NA NA 23.410 8.400 0.00 0.000 64.12 8 NA NA 0.00

Biotechnology & Drugs CGPI CollaGenex Pharmaceutical, Inc NASD Healthcare 114.020 NA NA 7.91 2.91 40.98 14.410 14.200 53.78 -1.110 1.49 2 NA NA 4.72

Biotechnology & Drugs CBRX Columbia Laboratories NASD Healthcare 140.290 NA NA 3.36 NA NA 41.750 40.800 40.61 -0.440 2.28 1 NA NA 2.10

Biotechnology & Drugs CBTE Commonwealth Biotechnologies, Inc. NASD Healthcare 15.610 NA NA 4.87 2.76 NA 3.200 2.900 9.68 0.030 9.49 0 NA 0.87 3.58

Biotechnology & Drugs COGE Compare Generiks, Inc. OTC Healthcare 0.000 NA NA 0.00 0.25 6.39 4.910 3.800 NA NA 22.69 NA NA NA 1.34

Biotechnology & Drugs CGEN Compugen Ltd. (USA) NASD Healthcare 86.780 NA NA 3.13 1.89 NA 27.730 18.300 29.02 0.220 34.00 0 NA NA 10.18

Biotechnology & Drugs CNCT Connetics Corporation NASD Healthcare 627.620 0.83 32.04 18.04 6.58 37.90 34.790 34.500 95.00 1.930 0.84 -34 NA 3.04 9.20





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 08Jul05 20 of 45 10/24/2011 3:30 PM

BioTech Industry 08Jul05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs VEGF Corautus Genetics Inc. NASD Healthcare 61.060 NA NA 4.11 8.42 NA 14.860 11.800 21.55 0.370 20.58 0 NA 1.46 6.05

Biotechnology & Drugs CORT Corcept Therapeutics Incorporated NASD Healthcare 132.990 -0.17 30.00 5.86 3.27 NA 22.690 9.100 24.28 -0.250 59.90 -21 NA NA 26.23

Biotechnology & Drugs CONX Corgenix Medical Corporation OTC Healthcare 2.120 NA NA 0.34 2.59 NA 6.230 4.700 0.00 0.000 24.52 1 NA 1.15 1.31

Biotechnology & Drugs CGTK Corgentech, Inc. NASD Healthcare 77.290 NA NA 2.75 0.82 NA 28.110 17.400 35.52 -4.170 38.09 0 NA 0.01 5.70

Biotechnology & Drugs CRXA Corixa Corporation NASD Healthcare 262.460 NA NA 4.40 34.03 NA 59.650 52.500 55.43 2.010 11.99 0 NA 16.44 2.95

Biotechnology & Drugs COR Cortex Pharmaceuticals AMEX Healthcare 76.340 NA NA 2.33 3.20 NA 32.760 32.400 5.88 0.030 1.11 2 NA NA 10.88

Biotechnology & Drugs CTRX Cotherix, Inc NASD Healthcare 252.680 -0.19 30.00 10.55 3.65 NA 23.950 13.600 25.33 3.340 43.22 0 NA NA 5.09

Biotechnology & Drugs CVGR Covalent Group, Inc. NASD Healthcare 29.430 NA NA 2.18 3.82 NA 13.500 10.600 33.39 1.900 21.48 0 NA 0.01 2.95

Biotechnology & Drugs CVD Covance Inc. NYSE Healthcare 2,905.690 1.42 16.89 46.11 4.30 28.38 63.020 62.600 86.15 3.880 0.66 -21 NA NA 2.57

Biotechnology & Drugs CRTX Critical Therapeutics, Inc. NASD Healthcare 239.670 NA NA 7.04 3.00 NA 34.040 16.700 12.19 -0.100 50.95 15 NA 0.03 4.83

Biotechnology & Drugs CRXL Crucell N.V. (ADR) NASD Healthcare 809.000 NA NA 21.94 8.63 NA 36.870 32.400 13.47 -0.190 12.13 0 NA 0.02 5.70

Biotechnology & Drugs CBST Cubist Pharmaceuticals NASD Healthcare 747.370 NA NA 14.04 25.00 NA 53.230 53.200 87.82 1.620 0.06 1 NA 5.53 3.95

Biotechnology & Drugs CRGN CuraGen Corporation NASD Healthcare 303.040 NA NA 5.97 3.50 NA 50.760 43.300 68.04 1.920 14.70 0 NA 2.77 15.95

Biotechnology & Drugs CRIS Curis, Inc. NASD Healthcare 202.140 NA NA 4.22 4.29 NA 47.900 46.800 35.44 0.450 2.30 -6 NA 0.10 5.84

Biotechnology & Drugs CVTX CV Therapeutics, Inc. NASD Healthcare 890.270 NA NA 24.71 15.03 NA 36.030 35.700 95.00 2.990 0.91 1 NA 5.57 8.14

Biotechnology & Drugs CYAN Cyanotech Corporation NASD Healthcare 24.450 NA NA 1.17 1.62 50.87 20.900 16.800 11.59 0.030 19.60 0 NA 0.14 3.97

Biotechnology & Drugs CYPB Cypress Bioscience, Inc. NASD Healthcare 399.230 NA NA 13.13 4.37 NA 30.410 28.400 73.28 -0.590 6.60 0 NA 0.00 21.76

Biotechnology & Drugs CYTO Cytogen Corporation NASD Healthcare 82.270 NA NA 5.30 2.44 NA 15.520 15.500 53.07 0.200 0.14 1 NA 0.07 4.28

Biotechnology & Drugs CYTK Cytokinetics, Inc. NASD Healthcare 248.410 NA NA 8.71 2.55 NA 28.520 17.900 42.14 0.680 37.24 -3 NA 0.10 8.67

Biotechnology & Drugs GTF Cytomedix, Inc. AMEX Healthcare 110.210 NA NA 4.70 15.89 NA 23.450 19.700 1.21 0.000 15.98 4 NA NA 2.83

Biotechnology & Drugs CYTR CytRx Corporation NASD Healthcare 49.490 NA NA 0.86 2.71 NA 57.540 53.500 14.22 5.940 7.02 0 NA NA 8.20

Biotechnology & Drugs DKHR D&K Healthcare Resources Inc NASD Healthcare 121.220 5.88 11.67 8.50 0.67 30.80 14.260 13.300 72.66 0.250 6.74 0 0.71 1.48 2.09

Biotechnology & Drugs DATA DATATRAK International, Inc. NASD Healthcare 122.930 NA NA 18.15 10.97 88.97 6.770 5.500 41.02 0.470 18.80 -13 NA NA 7.02

Biotechnology & Drugs DCGN deCODE genetics, Inc. NASD Healthcare 541.100 NA NA 9.92 15.22 NA 54.550 47.900 38.16 -0.950 12.18 -4 NA 4.54 6.83

Biotechnology & Drugs DGENQ Deltagen, Inc. OTC Healthcare 3.890 NA NA 0.10 0.29 NA 38.850 14.000 15.91 0.000 63.97 0 NA 0.37 0.23

Biotechnology & Drugs DNDN Dendreon Corporation NASD Healthcare 345.920 NA NA 5.84 1.92 NA 59.230 58.600 44.26 -8.000 1.07 8 NA 0.03 12.31

Biotechnology & Drugs DEPO DepoMed, Inc. NASD Healthcare 178.800 -0.25 30.00 4.50 16.47 NA 39.730 29.300 65.08 2.680 26.26 0 NA 0.46 2.43

Biotechnology & Drugs DSCI Derma Sciences, Inc. OTC Healthcare 7.370 NA NA 0.60 0.98 NA 12.280 3.900 0.21 0.000 68.25 1 NA 0.52 1.55

Biotechnology & Drugs DIGE Digene Corporation NASD Healthcare 600.850 3.35 30.00 30.00 7.17 49.59 20.030 15.200 84.99 0.810 24.11 -5 NA 0.01 5.08

Biotechnology & Drugs DSCO Discovery Laboratories NASD Healthcare 413.730 NA NA 7.73 10.48 NA 53.520 50.100 37.77 -2.530 6.40 -1 NA 0.28 7.41

Biotechnology & Drugs DPII Discovery Partners Int'l NASD Healthcare 77.790 NA NA 2.97 0.74 NA 26.190 25.500 86.71 2.190 2.64 0 NA NA 13.98

Biotechnology & Drugs DVSA Diversa Corporation NASD Healthcare 249.810 -0.14 50.00 5.68 1.78 NA 43.980 26.100 45.04 -0.610 40.66 2 NA 0.12 4.50

Biotechnology & Drugs DOCP DocPlanet.com Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 7.600 4.100 0.03 0.000 46.02 0 NA NA 0.38

Biotechnology & Drugs DOR DOR BioPharma, Inc. AMEX Healthcare 18.220 NA NA 0.36 3.48 NA 50.610 48.300 10.44 3.670 4.57 0 NA 0.02 3.09

Biotechnology & Drugs DOVP DOV Pharmaceutical, Inc. NASD Healthcare 449.510 NA NA 19.75 19.75 NA 22.760 21.000 79.96 0.190 7.73 -2 NA 3.52 6.72

Biotechnology & Drugs RDY Dr Reddy's Laboratories Limited (ADR) NYSE Healthcare 1,354.170 NA NA 17.70 2.75 66.04 76.520 56.600 17.46 0.010 26.03 0 0.65 0.10 2.70

Biotechnology & Drugs DRUG Dragon Pharmaceuticals Inc. (USA) OTC Healthcare 55.960 NA NA 0.89 1.74 NA 62.880 49.800 0.00 0.000 20.80 0 NA 1.33 1.02

Biotechnology & Drugs DRAX DRAXIS Health Inc. (USA) NASD Healthcare 197.850 NA NA 4.79 2.68 20.13 41.300 33.900 40.01 1.570 17.93 0 NA NA 3.18

Biotechnology & Drugs DRRX DURECT Corporation NASD Healthcare 261.220 NA NA 5.03 20.10 NA 51.930 37.300 45.74 -4.870 28.18 5 NA 4.77 6.32

Biotechnology & Drugs DUSA DUSA Pharmaceuticals, Inc NASD Healthcare 160.410 -0.26 48.55 9.48 3.33 NA 16.920 15.800 60.30 0.230 6.63 -3 NA 0.00 13.98

Biotechnology & Drugs DIL Dyadic International, Inc. AMEX Healthcare 51.600 NA NA 2.32 2.38 NA 22.240 15.100 2.98 0.060 32.11 -1 NA 0.17 6.02

Biotechnology & Drugs DYAX Dyax Corp. NASD Healthcare 149.790 NA NA 4.74 3.78 NA 31.600 29.900 52.76 -2.250 5.38 0 NA 0.30 2.99

Biotechnology & Drugs DVAX Dynavax Technologies Corp NASD Healthcare 118.790 NA NA 4.80 1.82 NA 24.750 20.300 36.89 1.340 17.97 -4 NA NA 13.87

Biotechnology & Drugs EPEI EAPI Entertainment, Inc. OTC Healthcare 14.900 NA NA 0.93 NA NA 16.020 13.600 NA NA 15.13 NA NA NA 0.01

Biotechnology & Drugs EW Edwards Lifesciences Corp NYSE Healthcare 2,511.780 1.62 13.42 42.19 3.87 27.72 59.540 56.600 93.01 -0.160 4.93 -7 NA 0.43 2.27

Biotechnology & Drugs ESALY Eisai Co., Ltd (ADR) OTC Healthcare 9,930.840 2.72 6.50 34.75 2.42 NA 285.790 211.500 0.32 0.000 26.00 0 NA 0.00 2.44

Biotechnology & Drugs ELN Elan Corporation, plc (ADR) NYSE Healthcare 2,856.540 -0.72 9.86 7.23 31.40 NA 395.100 387.200 28.10 -107.440 2.00 0 NA 24.81 3.58

Biotechnology & Drugs ELI Elite Pharmaceuticals, Inc. AMEX Healthcare 46.630 NA NA 2.98 6.17 NA 15.650 15.600 23.51 3.090 0.31 -1 NA 0.43 5.32

Biotechnology & Drugs EMBX Embrex, Inc. NASD Healthcare 90.240 NA NA 11.35 1.89 33.28 7.950 7.100 42.87 0.030 10.69 -2 NA 0.19 2.63

Biotechnology & Drugs EMIS Emisphere Technologies NASD Healthcare 89.640 NA NA 3.85 10.58 NA 23.280 22.900 37.28 2.950 1.65 0 NA 2.84 1.18

Biotechnology & Drugs ENCY Encysive Pharmaceuticals, Inc. NASD Healthcare 645.860 NA NA 11.12 14.36 NA 58.080 57.200 86.51 9.720 1.52 -7 NA 2.93 10.18

Biotechnology & Drugs ENDP Endo Pharmaceuticals NASD Healthcare 3,393.260 0.99 15.96 25.72 5.06 29.43 131.930 68.800 55.25 1.320 47.85 0 NA NA 2.16

Biotechnology & Drugs EVSC Endovasc, Inc. OTC Healthcare 5.530 NA NA 0.05 21.52 NA 116.460 109.100 0.04 0.030 6.32 0 NA 0.76 0.09

Biotechnology & Drugs ENMD EntreMed, Inc. NASD Healthcare 117.080 NA NA 2.35 3.18 NA 49.820 22.900 16.16 0.230 54.03 3 NA NA 9.28

Biotechnology & Drugs ETOP Entropin, Inc. OTC Healthcare 2.150 NA NA 0.07 NA NA 30.650 23.300 NA NA 23.97 NA NA NA 8.28

Biotechnology & Drugs ENZN Enzon Pharmaceuticals, Inc. NASD Healthcare 338.150 2.96 39.00 7.71 1.18 NA 43.860 43.800 76.54 0.120 0.14 1 NA 1.40 6.85

Biotechnology & Drugs ELAB Eon Labs, Inc. NASD Healthcare 2,726.080 1.13 19.30 30.67 5.79 24.58 88.880 28.400 24.09 -6.270 68.05 0 NA NA 5.20

Biotechnology & Drugs EPMN Epimmune Inc. NASD Healthcare 11.970 NA NA 0.75 1.37 NA 16.020 13.300 13.97 -0.030 17.00 0 NA NA 2.45

Biotechnology & Drugs EPIX EPIX Pharmaceuticals, Inc. NASD Healthcare 238.150 NA NA 10.24 6.69 NA 23.260 23.000 61.34 -4.310 1.11 0 NA 3.23 5.50

Biotechnology & Drugs ERGO Ergo Science Corporation OTC Healthcare 13.900 NA NA 2.39 0.64 NA 5.810 5.500 2.24 0.020 5.40 0 NA NA 25.47

Biotechnology & Drugs EXAS EXACT Sciences Corporation NASD Healthcare 60.370 NA NA 2.30 1.79 NA 26.250 22.300 48.83 -0.670 15.04 0 NA 0.13 7.85

Biotechnology & Drugs EXEG eXegenics Inc. OTC Healthcare 6.020 NA NA 0.37 0.64 NA 16.270 15.300 4.65 0.000 5.95 0 NA NA 50.22

Biotechnology & Drugs EXEL Exelixis, Inc. NASD Healthcare 640.970 -0.44 15.00 8.40 19.36 NA 76.310 53.900 75.83 -1.910 29.36 -16 NA 4.32 2.09

Biotechnology & Drugs EYET Eyetech Pharmaceuticals, Inc. NASD Healthcare 557.290 -0.49 42.00 12.90 4.10 NA 43.200 35.100 77.98 2.320 18.75 -16 NA 0.02 6.21

Biotechnology & Drugs FVRL Favrille, Inc. NASD Healthcare 89.320 NA NA 4.40 1.47 NA 20.300 6.000 12.39 2.520 70.44 10 NA 0.10 9.99





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 08Jul05 21 of 45 10/24/2011 3:30 PM

BioTech Industry 08Jul05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs FHRX First Horizon Pharmaceutical Corp. NASD Healthcare 729.850 0.56 38.42 20.85 2.33 26.94 35.000 28.000 95.00 -1.660 20.01 0 NA 0.48 7.47

Biotechnology & Drugs FLML Flamel Technologies S.A. (ADR) NASD Healthcare 433.730 NA NA 19.94 3.72 41.54 21.750 21.100 47.77 1.450 3.00 0 NA NA NA

Biotechnology & Drugs FMTI Forbes Medi-Tech Inc. (USA) NASD Healthcare 73.370 NA NA 2.16 2.93 NA 33.970 33.600 7.99 -0.400 1.08 0 NA 0.04 4.65

Biotechnology & Drugs FRX Forest Laboratories, Inc. NYSE Healthcare 13,652.530 1.04 16.18 40.10 4.45 17.89 340.460 335.200 91.84 -15.680 1.55 -2 NA NA 4.80

Biotechnology & Drugs GGEN GalaGen Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 12.280 7.500 0.08 0.000 38.90 0 NA NA 0.37

Biotechnology & Drugs GCAN GammaCan International, Inc. OTC Healthcare 26.230 NA NA 1.00 20.43 NA 26.230 21.200 NA NA 19.18 NA NA NA 15.99

Biotechnology & Drugs GSAC GelStat Corporation OTC Healthcare 9.840 NA NA 0.70 8.43 NA 14.060 13.900 1.69 0.060 1.15 2 NA 0.29 1.45

Biotechnology & Drugs GENR Genaera Corporation NASD Healthcare 97.190 NA NA 1.70 4.06 NA 57.170 56.700 23.40 -1.220 0.82 0 NA NA 10.66

Biotechnology & Drugs GNSC Genaissance Pharm. Inc. NASD Healthcare 40.260 NA NA 1.14 2.48 NA 35.350 26.700 25.51 0.580 24.47 0 NA 0.27 1.71

Biotechnology & Drugs GLGC Gene Logic Inc. NASD Healthcare 113.310 NA NA 3.57 0.67 NA 31.740 31.200 41.73 -2.120 1.70 1 NA 0.01 3.87

Biotechnology & Drugs GNLB Genelabs Technologies NASD Healthcare 47.970 NA NA 0.54 4.74 NA 88.500 82.500 22.24 2.780 6.78 0 NA 0.03 3.19

Biotechnology & Drugs GMXX GeneMax Corporation OTC Healthcare 5.830 NA NA 0.20 NA NA 29.170 21.700 0.00 0.000 25.61 0 NA NA 0.55

Biotechnology & Drugs DNA Genentech, Inc. NYSE Healthcare 87,865.020 2.32 31.65 83.17 12.55 100.21 1,056.450 454.300 39.68 1.680 57.00 -40 NA 0.07 2.90

Biotechnology & Drugs GNBT Generex Biotechnology NASD Healthcare 24.670 NA NA 0.62 3.93 NA 39.790 34.200 1.57 -0.280 14.05 1 NA 0.79 0.16

Biotechnology & Drugs GBI Genesis Bioventures, Inc. AMEX Healthcare 4.910 NA NA 0.16 1.83 NA 30.660 20.500 0.00 -0.050 33.14 0 NA 0.88 0.00

Biotechnology & Drugs GTOP Genitope Corporation NASD Healthcare 364.360 NA NA 12.90 3.33 NA 28.250 24.400 38.40 1.680 13.61 -22 NA 0.00 30.06

Biotechnology & Drugs GNTA Genta Incorporated NASD Healthcare 112.520 NA NA 1.18 7.13 NA 95.360 93.900 15.37 -4.710 1.53 0 NA 0.28 1.46

Biotechnology & Drugs GNT Gentium S.p.A. AMEX Healthcare 69.760 NA NA 8.99 NA NA 7.760 7.760 NA NA 0.00 NA NA NA NA

Biotechnology & Drugs GNVC GenVec, Inc. NASD Healthcare 105.710 NA NA 1.90 3.90 NA 55.640 40.900 18.63 -0.380 26.49 1 NA 0.16 4.40

Biotechnology & Drugs GENZ Genzyme Corporation NASD Healthcare 15,633.940 1.51 18.27 61.97 3.46 142.46 252.280 227.500 88.78 8.590 9.82 -18 NA 0.19 3.00

Biotechnology & Drugs GORX GeoPharma, Inc. NASD Healthcare 15.690 NA NA 1.81 1.00 NA 8.670 3.600 14.45 0.540 58.48 0 NA 0.24 3.42

Biotechnology & Drugs GERN Geron Corporation NASD Healthcare 472.870 NA NA 8.53 3.65 NA 55.440 53.000 21.06 -0.850 4.39 -6 NA 0.02 25.18

Biotechnology & Drugs GILD Gilead Sciences, Inc. NASD Healthcare 21,067.980 1.58 20.59 46.63 10.18 43.70 451.810 447.700 87.96 18.240 0.91 -21 NA 0.00 7.66

Biotechnology & Drugs GLIAQ Gliatech Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 9.680 7.800 0.05 0.000 19.45 0 NA NA 0.90

Biotechnology & Drugs GLGS GlycoGenesys, Inc. NASD Healthcare 10.290 NA NA 1.02 16.78 NA 10.080 8.000 3.63 -0.190 20.67 0 NA NA 1.04

Biotechnology & Drugs GPCB GPC Biotech AG (ADR) NASD Healthcare 316.390 NA NA 10.52 2.08 NA 30.080 27.100 0.98 0.040 9.90 0 NA 0.01 11.37

Biotechnology & Drugs GTCB GTC Biotherapeutics, Inc. NASD Healthcare 77.760 NA NA 1.66 2.18 NA 46.840 40.800 17.60 2.010 12.90 6 NA 0.44 2.05

Biotechnology & Drugs GTXI GTx, Inc. NASD Healthcare 268.110 NA NA 10.87 4.87 NA 24.660 7.700 22.67 0.050 68.78 6 NA 0.00 8.88

Biotechnology & Drugs GLFD Guilford Pharmaceuticals NASD Healthcare 105.120 NA NA 2.26 NA NA 46.510 43.900 75.00 -2.340 5.62 5 NA NA 3.98

Biotechnology & Drugs HTI Halozyme Therapeutics, Inc. AMEX Healthcare 86.870 NA NA 1.74 7.27 NA 49.920 45.600 12.89 0.710 8.66 2 NA NA 7.02

Biotechnology & Drugs HNAB Hana Biosciences, Inc. OTC Healthcare 32.660 NA NA 1.80 6.37 NA 18.140 13.400 9.36 1.320 26.14 10 NA NA 3.44

Biotechnology & Drugs VGENQ Harvard Scientific Corp. OTC Healthcare 0.000 NA NA 0.00 NA NA 29.330 5.900 NA NA 79.88 NA NA NA NA

Biotechnology & Drugs HKRRF Hawker Resources Inc. (USA) OTC Healthcare 206.520 NA NA 4.23 1.90 NA 48.820 40.500 2.46 1.200 17.05 0 NA 0.02 2.52

Biotechnology & Drugs HDVY Health Discovery Corporation OTC Healthcare 21.620 NA NA 0.22 10.38 NA 98.270 65.800 NA NA 33.04 NA NA 0.94 1.04

Biotechnology & Drugs HESG Health Sciences Group, Inc. OTC Healthcare 18.650 NA NA 0.81 NA NA 23.030 11.700 NA NA 49.19 NA NA NA 0.51

Biotechnology & Drugs HCTL Healthcare Technologies NASD Healthcare 5.240 NA NA 0.68 NA NA 7.700 2.800 0.23 0.000 63.65 0 NA NA NA

Biotechnology & Drugs HXBM Helix BioMedix, Inc. OTC Healthcare 19.790 NA NA 1.30 3.94 NA 15.220 13.000 NA NA 14.59 NA NA NA 13.06

Biotechnology & Drugs HEMA HemaCare Corporation OTC Healthcare 13.750 NA NA 1.70 2.52 9.04 8.090 7.800 1.32 0.020 3.54 1 NA 0.17 2.13

Biotechnology & Drugs HMGN Hemagen Diagnostics, Inc. OTC Healthcare 5.930 NA NA 0.39 NA NA 15.200 12.400 0.28 0.000 18.44 -1 NA NA 2.90

Biotechnology & Drugs HEB Hemispherx BioPharma, Inc AMEX Healthcare 93.640 NA NA 1.86 5.42 NA 50.350 43.300 4.87 0.790 13.99 9 NA 0.24 3.28

Biotechnology & Drugs HMSLD Hemosol Corp. (USA) NASD Healthcare 13.050 NA NA 0.86 0.24 NA 15.170 13.500 NA NA 11.01 NA NA 0.32 0.40

Biotechnology & Drugs HSKA Heska Corporation NASD Healthcare 31.650 NA NA 0.64 23.99 NA 49.450 28.900 37.81 -0.090 41.56 4 NA 9.30 1.07

Biotechnology & Drugs HITK Hi-Tech Pharmacal Co. NASD Healthcare 255.310 NA NA 32.96 3.76 38.28 7.750 6.800 38.47 -0.040 12.21 -3 NA NA 6.35

Biotechnology & Drugs HEPH Hollis-Eden Pharmaceuticals Inc. NASD Healthcare 150.520 -0.10 50.00 7.80 2.93 NA 19.300 17.900 30.48 -0.500 7.24 -1 NA NA 12.69

Biotechnology & Drugs HSP Hospira, Inc. NYSE Healthcare 6,160.480 3.48 6.40 38.97 5.72 19.54 158.080 156.500 63.29 1.160 1.00 1 NA 0.65 2.44

Biotechnology & Drugs HBSC Human BioSystems OTC Healthcare 39.120 NA NA 0.73 NA NA 53.590 53.300 NA NA 0.53 NA NA NA 0.37

Biotechnology & Drugs HGSI Human Genome Sciences NASD Healthcare 1,730.780 -0.42 15.00 13.25 2.94 NA 130.620 127.800 85.61 8.480 2.16 -1 NA 0.86 9.84

Biotechnology & Drugs HBY Hybridon, Inc. AMEX Healthcare 59.960 NA NA 0.54 6.20 NA 111.030 91.100 5.14 -0.960 17.95 5 NA NA 6.77

Biotechnology & Drugs ICGN Icagen, Inc. NASD Healthcare 162.080 NA NA 7.46 3.38 NA 21.730 5.000 18.17 3.950 76.99 4 NA 0.03 8.49

Biotechnology & Drugs ICLR ICON plc (ADR) NASD Healthcare 527.240 1.23 17.50 37.99 2.28 36.35 13.880 13.600 74.22 0.790 2.00 0 NA 0.00 1.95

Biotechnology & Drugs ICOR Icoria, Inc. OTC Healthcare 4.860 NA NA 0.12 0.37 NA 39.680 36.500 5.17 -0.020 8.02 0 NA 0.48 1.99

Biotechnology & Drugs ICOS ICOS Corporation NASD Healthcare 1,414.190 -0.40 44.00 22.15 NA NA 63.850 63.500 66.52 3.130 0.54 -5 NA NA 4.82

Biotechnology & Drugs IDBE ID Biomedical Corporation (USA) NASD Healthcare 745.670 NA NA 17.32 6.78 NA 43.050 42.200 18.12 -0.190 1.98 0 NA 0.97 1.85

Biotechnology & Drugs IDIX Idenix Pharmaceuticals, Inc. NASD Healthcare 1,143.810 -0.38 40.00 23.75 11.27 NA 48.160 13.700 19.42 1.890 71.55 0 NA 0.03 4.77

Biotechnology & Drugs IDXX IDEXX Laboratories, Inc. NASD Healthcare 2,058.010 1.89 14.25 63.14 5.33 28.56 32.590 32.500 92.62 -0.020 0.29 -5 NA 0.00 3.37

Biotechnology & Drugs IG IGI, Inc. AMEX Healthcare 14.880 NA NA 1.26 3.83 NA 11.810 8.100 3.29 -0.020 31.41 0 NA 0.00 1.96

Biotechnology & Drugs IMCL ImClone Systems Incorporated NASD Healthcare 2,834.460 1.76 15.22 33.89 13.64 43.12 83.640 69.100 70.95 0.710 17.38 -5 NA 2.90 4.40

Biotechnology & Drugs ICRP IMCOR Pharmaceutical Co. OTC Healthcare 1.980 NA NA 0.40 0.21 NA 4.960 2.500 NA NA 49.56 NA NA 0.02 0.35

Biotechnology & Drugs IME IMI International Medical Innov. (USA) AMEX Healthcare 38.970 NA NA 1.81 31.22 NA 21.530 19.200 5.02 0.190 10.82 0 NA NA 3.01

Biotechnology & Drugs IMM Immtech International, Inc. AMEX Healthcare 127.780 NA NA 11.20 31.82 NA 11.410 8.700 8.76 0.070 23.74 0 NA NA 3.28

Biotechnology & Drugs ICCC ImmuCell Corporation NASD Healthcare 11.600 NA NA 4.15 1.45 57.64 2.790 2.300 0.22 -0.050 17.71 0 NA NA 6.25

Biotechnology & Drugs IMMFF Immune Network Ltd. OTC Healthcare 0.150 NA NA 0.01 NA NA 20.920 12.800 NA NA 38.81 NA NA NA 0.05

Biotechnology & Drugs IMGN ImmunoGen, Inc. NASD Healthcare 261.230 NA NA 6.37 2.92 NA 41.010 40.400 36.15 -0.100 1.49 -3 NA NA 9.13

Biotechnology & Drugs IMMU Immunomedics, Inc. NASD Healthcare 100.040 NA NA 1.85 11.16 NA 54.070 43.400 29.38 0.340 19.74 -1 NA 1.58 1.32

Biotechnology & Drugs IPXLE Impax Laboratories Inc. NASD Healthcare 898.910 2.60 24.38 15.37 10.41 1,921.25 58.480 40.000 71.08 5.150 31.61 3 NA 1.25 4.44





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 08Jul05 22 of 45 10/24/2011 3:30 PM

BioTech Industry 08Jul05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs INCY Incyte Corporation NASD Healthcare 709.030 -0.39 15.00 8.53 11.84 NA 83.120 75.600 76.20 -7.820 9.05 1 NA 6.33 21.14

Biotechnology & Drugs IDEV Indevus Pharmaceuticals NASD Healthcare 133.940 NA NA 2.85 NA NA 47.000 40.800 43.88 -0.720 13.19 1 NA NA 4.57

Biotechnology & Drugs INHX Inhibitex, Inc. NASD Healthcare 178.880 NA NA 7.10 2.52 NA 25.190 10.600 19.35 -0.020 57.93 0 NA 0.04 7.26

Biotechnology & Drugs INKP InKine Pharmaceutical Company, Inc. NASD Healthcare 164.520 NA NA 3.35 11.12 50.76 49.110 47.900 41.82 -0.380 2.47 0 NA NA 6.22

Biotechnology & Drugs ISV Insite Vision Inc. AMEX Healthcare 50.480 NA NA 0.64 NA NA 78.880 68.800 7.69 -0.540 12.78 0 NA NA 0.84

Biotechnology & Drugs INSM Insmed Incorporated NASD Healthcare 43.640 NA NA 0.97 2.49 NA 44.990 42.100 19.97 -0.840 6.42 0 NA 1.06 8.72

Biotechnology & Drugs ISPH Inspire Pharmaceuticals, Inc. NASD Healthcare 386.170 -0.26 30.00 9.18 2.84 NA 42.070 41.500 91.50 2.980 1.35 -1 NA 0.01 11.65

Biotechnology & Drugs INB Integrated BioPharma, Inc. AMEX Healthcare 34.360 NA NA 2.72 1.78 NA 12.630 5.900 3.76 0.120 53.29 -4 NA 0.22 2.01

Biotechnology & Drugs IFSC Interferon Sciences, Inc. OTC Healthcare 4.110 NA NA 0.11 4.99 NA 37.340 20.900 0.46 0.000 44.03 0 NA 0.27 2.06

Biotechnology & Drugs ITMN InterMune, Inc. NASD Healthcare 487.630 NA NA 14.96 31.59 NA 32.600 25.400 82.16 1.240 22.08 30 NA 11.04 3.26

Biotechnology & Drugs INIS International Isotopes Inc. OTC Healthcare 13.950 NA NA 0.08 10.72 NA 183.570 114.800 NA NA 37.46 NA NA 1.14 1.72

Biotechnology & Drugs IPA Interpharm Holdings, Inc. AMEX Healthcare 34.930 NA NA 1.34 1.48 NA 26.060 19.300 3.47 -0.010 25.95 0 NA 0.57 1.35

Biotechnology & Drugs IBCL Int'l BioChemical Industries, Inc. OTC Healthcare 0.030 NA NA 0.00 NA NA 94.160 92.500 0.01 0.000 1.77 0 NA NA 0.02

Biotechnology & Drugs IBPI IntraBiotics Pharmaceuticals NASD Healthcare 31.740 NA NA 3.50 0.66 NA 9.070 7.300 57.55 0.100 19.50 8 NA NA 89.68

Biotechnology & Drugs INGN Introgen Therapeutics, Inc NASD Healthcare 196.030 NA NA 6.34 7.42 NA 30.920 20.800 27.20 2.240 32.73 0 NA 0.33 5.15

Biotechnology & Drugs IMA Inverness Medical Innovations, Inc. AMEX Healthcare 609.290 1.65 25.00 26.25 1.70 NA 23.210 19.100 49.62 0.850 17.71 -2 NA 0.66 1.70

Biotechnology & Drugs IVRO InVitro International OTC Healthcare 0.350 NA NA 0.02 0.85 24.00 14.510 9.000 NA NA 37.96 NA NA NA 9.37

Biotechnology & Drugs IVGN Invitrogen Corporation NASD Healthcare 4,473.310 1.58 15.28 86.13 2.27 38.35 51.940 51.500 95.00 2.300 0.84 1 NA 0.67 7.53

Biotechnology & Drugs IOX IOMED, Inc. AMEX Healthcare 18.370 NA NA 2.79 6.21 29.06 6.590 4.000 3.19 0.000 39.26 -1 NA 0.15 5.83

Biotechnology & Drugs ISIS ISIS Pharmaceuticals, Inc. NASD Healthcare 235.860 NA NA 4.10 NA NA 57.530 51.600 53.49 0.290 10.31 -1 NA NA 2.69

Biotechnology & Drugs ILE Isolagen, Inc. AMEX Healthcare 130.670 NA NA 4.32 5.78 NA 30.250 28.400 48.51 0.760 6.11 25 NA 3.98 12.01

Biotechnology & Drugs ISTA ISTA Pharmaceuticals NASD Healthcare 232.090 -0.26 26.67 8.98 3.85 NA 25.840 17.200 87.22 6.090 33.45 -30 NA NA 12.35

Biotechnology & Drugs ITER IT&E International Group OTC Healthcare 4.770 NA NA 0.25 6.86 NA 19.080 18.900 NA NA 0.96 NA NA 7.19 2.52

Biotechnology & Drugs IVX IVAX Corporation AMEX Healthcare 5,670.100 1.13 22.64 21.53 3.78 30.76 263.360 200.500 59.69 14.480 23.87 2 NA 0.76 2.88

Biotechnology & Drugs KNDL Kendle International Inc. NASD Healthcare 188.780 NA NA 14.18 1.81 38.12 13.310 11.000 59.24 -0.220 17.37 -14 NA 0.10 1.86

Biotechnology & Drugs KERX Keryx Biopharmaceuticals NASD Healthcare 442.950 NA NA 14.06 11.48 NA 31.500 26.400 64.72 2.740 16.20 0 NA NA 10.59

Biotechnology & Drugs KG King Pharmaceuticals NYSE Healthcare 2,613.110 1.18 9.70 10.81 1.36 186.38 241.730 239.800 75.73 -8.120 0.80 0 NA 0.18 1.92

Biotechnology & Drugs KOSP KOS Pharmaceuticals, Inc. NASD Healthcare 2,854.830 1.21 21.53 70.65 6.12 19.73 40.410 16.000 39.97 0.750 60.40 -32 NA 0.04 2.71

Biotechnology & Drugs KOSN Kosan Biosciences Incorporated NASD Healthcare 159.670 NA NA 5.47 2.60 NA 29.190 22.700 52.42 -0.230 22.23 0 NA 0.07 5.57

Biotechnology & Drugs KV.A K-V Pharmaceutical Company NYSE Healthcare 813.210 1.14 18.88 16.50 2.78 27.09 49.290 37.600 67.14 -1.200 23.71 -3 NA 0.72 9.71

Biotechnology & Drugs LJPC La Jolla Pharmaceutical Company NASD Healthcare 60.600 NA NA 0.82 1.74 NA 73.900 73.600 22.50 -3.120 0.41 1 NA 0.04 4.94

Biotechnology & Drugs LCI Lannett Company, Inc. AMEX Healthcare 127.040 NA NA 5.28 1.70 NA 24.060 10.100 5.29 0.240 58.02 8 NA 0.14 2.57

Biotechnology & Drugs LSBC Large Scale Biology Corp. NASD Healthcare 29.910 NA NA 0.95 5.30 NA 31.490 24.500 9.58 0.340 22.19 0 NA 0.62 0.63

Biotechnology & Drugs LCAR Lescarden Inc. OTC Healthcare 12.230 NA NA 0.41 NA NA 29.830 20.100 0.06 0.000 32.62 0 NA NA 0.58

Biotechnology & Drugs LEXG Lexicon Genetics Incorporated NASD Healthcare 322.290 NA NA 5.07 2.97 NA 63.570 57.600 52.90 -0.010 9.39 0 NA 0.35 2.29

Biotechnology & Drugs LSRI Life Sciences Research Inc. OTC Healthcare 147.400 0.65 25.00 11.77 106.06 9.58 12.520 10.300 11.33 0.620 17.75 1 NA 64.08 1.07

Biotechnology & Drugs LIFC LifeCell Corporation NASD Healthcare 484.200 0.69 78.00 16.55 7.30 63.41 29.260 29.200 61.92 0.030 0.20 -1 NA NA 5.87

Biotechnology & Drugs LCBM Lifecore Biomedical, Inc. NASD Healthcare 150.290 0.41 45.00 11.54 2.71 22.67 13.020 12.000 61.85 1.540 7.86 -1 NA 0.10 6.77

Biotechnology & Drugs LGNDE Ligand Pharmaceuticals NASD Healthcare 561.150 -15.76 36.10 7.59 13.69 NA 73.930 69.500 80.69 -12.640 6.00 0 NA 4.25 1.75

Biotechnology & Drugs LIPD Lipid Sciences, Inc. NASD Healthcare 119.100 NA NA 4.78 8.18 NA 24.920 17.400 4.99 0.190 30.17 0 NA NA 8.05

Biotechnology & Drugs LRP Lorus Therapeutics Inc. (USA) AMEX Healthcare 110.250 NA NA 0.64 8.54 NA 172.260 170.500 1.85 0.980 1.02 0 NA 0.42 4.77

Biotechnology & Drugs LMNX Luminex Corporation NASD Healthcare 346.700 NA NA 11.07 7.67 NA 31.320 28.100 37.79 -0.210 10.28 0 NA NA 8.19

Biotechnology & Drugs MCHM MacroChem Corporation NASD Healthcare 10.400 NA NA 0.25 2.16 NA 41.610 40.700 23.91 0.190 2.19 0 NA NA 5.40

Biotechnology & Drugs MHTT Manhattan Pharmaceuticals, Inc. OTC Healthcare 56.840 NA NA 1.40 13.41 NA 40.600 15.800 4.56 0.020 61.08 55 NA NA 3.20

Biotechnology & Drugs MTEX Mannatech, Inc. NASD Healthcare 494.640 NA NA 18.20 8.38 23.79 27.180 16.600 16.68 0.060 38.92 1 1.54 0.00 1.70

Biotechnology & Drugs MNKD MannKind Corporation NASD Healthcare 357.610 NA NA 10.91 2.80 NA 32.780 16.700 13.36 0.020 49.05 0 NA NA 5.12

Biotechnology & Drugs MSHL Marshall Edwards, Inc. NASD Healthcare 427.040 NA NA 7.50 22.96 NA 56.940 6.800 1.02 0.220 88.06 0 NA NA 10.77

Biotechnology & Drugs MATK Martek Biosciences Corp. NASD Healthcare 1,281.880 2.26 42.50 40.48 2.82 24.46 31.670 30.400 95.00 4.190 4.00 -1 NA 0.15 4.54

Biotechnology & Drugs MZT Matritech, Inc. AMEX Healthcare 27.230 NA NA 0.62 8.95 NA 43.910 43.200 8.39 0.640 1.62 2 NA 0.32 3.09

Biotechnology & Drugs MTXX Matrixx Initiatives, Inc. NASD Healthcare 108.050 0.58 31.50 11.36 2.38 20.66 9.510 8.400 42.64 1.110 11.69 -6 NA 0.00 3.32

Biotechnology & Drugs MAXM Maxim Pharmaceuticals NASD Healthcare 36.040 NA NA 1.26 0.97 NA 28.610 28.500 17.90 -1.290 0.37 0 NA 0.02 5.57

Biotechnology & Drugs MAXY Maxygen, Inc. NASD Healthcare 293.400 NA NA 8.22 1.32 NA 35.690 26.100 35.79 0.210 26.88 -10 NA 0.00 24.44

Biotechnology & Drugs MDZ MDS Inc. (USA) NYSE Healthcare 2,376.180 1.46 15.00 16.77 1.91 NA 141.690 94.900 54.91 3.190 33.02 0 0.64 0.33 1.86

Biotechnology & Drugs MEDX Medarex, Inc. NASD Healthcare 1,029.290 NA NA 9.30 4.48 NA 110.680 109.400 54.66 -0.680 1.15 -5 NA 0.65 10.37

Biotechnology & Drugs MLSC Medical Discoveries, Inc. OTC Healthcare 10.170 NA NA 0.10 NA NA 107.100 84.200 0.00 0.000 21.38 0 NA NA 0.81

Biotechnology & Drugs MRX Medicis Pharmaceutical Corporation NYSE Healthcare 1,731.020 1.08 20.14 31.90 3.76 31.43 54.260 53.300 95.00 2.460 1.78 0 0.38 0.98 7.43

Biotechnology & Drugs MCU Medicure Inc. (USA) AMEX Healthcare 58.790 NA NA 0.88 5.99 NA 66.810 60.800 4.52 -1.610 8.99 0 NA NA 5.15

Biotechnology & Drugs MHUT Medi-Hut Co., Inc. OTC Healthcare 1.160 NA NA 0.08 0.07 0.78 14.470 10.400 1.15 0.170 28.11 2 NA NA 2.66

Biotechnology & Drugs MEDI MedImmune, Inc. NASD Healthcare 6,907.730 2.65 26.55 27.88 3.94 NA 247.770 246.400 84.80 1.760 0.55 -2 NA 0.29 2.04

Biotechnology & Drugs TOX MEDTOX Scientific, Inc. AMEX Healthcare 55.730 1.47 15.00 7.39 1.46 32.13 7.540 7.000 36.75 0.280 7.19 4 NA 0.34 1.24

Biotechnology & Drugs MEMY Memory Pharmaceuticals Corp. NASD Healthcare 41.820 NA NA 2.01 2.16 NA 20.810 13.500 38.80 1.000 35.12 -12 NA 0.18 2.79

Biotechnology & Drugs VIVO Meridian Bioscience, Inc. NASD Healthcare 321.700 2.09 13.75 20.48 7.19 30.71 15.710 11.600 37.00 0.570 26.15 -5 2.34 0.34 1.87

Biotechnology & Drugs MBRX Metabasis Therapeutics, Inc. NASD Healthcare 58.190 NA NA 3.20 1.61 NA 18.180 9.600 31.19 -0.070 47.20 0 NA 0.06 8.37

Biotechnology & Drugs MOGN MGi Pharma, Inc. NASD Healthcare 1,678.370 0.79 37.75 23.39 13.58 NA 71.760 71.500 90.41 -0.830 0.36 -5 NA 2.11 8.33

Biotechnology & Drugs MLAR Micro Laboratories, Inc. OTC Healthcare 1.300 NA NA 0.03 NA NA 49.960 9.500 NA NA 80.98 NA NA NA 0.00





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 08Jul05 23 of 45 10/24/2011 3:30 PM

BioTech Industry 08Jul05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs MII MicroIslet, Inc. AMEX Healthcare 52.330 NA NA 1.31 7.43 NA 39.940 24.900 7.07 0.250 37.66 0 NA NA 24.06

Biotechnology & Drugs MLNM Millennium Pharmaceuticals, Inc. NASD Healthcare 3,026.800 -1.80 15.00 9.84 1.35 NA 307.600 298.400 66.85 -2.260 2.99 0 NA 0.11 4.43

Biotechnology & Drugs MRVT Miravant Medical Technologies OTC Healthcare 18.270 NA NA 0.49 NA NA 37.300 35.600 8.72 -0.060 4.55 0 NA NA 1.79

Biotechnology & Drugs MNTA Momenta Pharmaceuticals, Inc. NASD Healthcare 489.520 NA NA 19.20 9.11 NA 25.500 13.100 14.50 -0.930 48.62 -12 NA 0.03 10.13

Biotechnology & Drugs MCET MultiCell Technologies, Inc. OTC Healthcare 33.190 NA NA 1.05 5.88 NA 31.610 22.760 0.00 0.000 28.00 -11 NA 0.07 3.93

Biotechnology & Drugs MYL Mylan Laboratories Inc. NYSE Healthcare 5,227.930 1.32 15.60 19.41 2.83 26.12 269.340 231.000 69.07 -8.960 14.24 -1 1.24 0.01 6.23

Biotechnology & Drugs MYMX Mymetics Corporation OTC Healthcare 8.540 NA NA 0.05 NA NA 170.710 117.800 0.18 -0.010 30.99 0 NA NA 0.05

Biotechnology & Drugs MYOG Myogen, Inc. NASD Healthcare 268.260 -0.17 20.00 7.50 2.99 NA 35.770 22.500 55.77 -0.150 37.10 -7 NA 0.02 5.80

Biotechnology & Drugs MYGN Myriad Genetics, Inc. NASD Healthcare 541.560 NA NA 17.60 3.76 NA 30.770 28.300 71.27 -1.230 8.03 -2 NA NA 6.09

Biotechnology & Drugs NABI Nabi Biopharmaceuticals NASD Healthcare 930.900 NA NA 15.82 3.45 NA 58.840 58.500 76.90 0.860 0.58 1 NA 0.05 2.58

Biotechnology & Drugs NSTK Nastech Pharmaceutical NASD Healthcare 265.070 NA NA 14.75 5.05 NA 17.970 12.700 24.28 0.080 29.33 -14 NA 0.07 6.58

Biotechnology & Drugs NHCT National Healthcare Technology, Inc. OTC Healthcare 0.200 NA NA 2.50 NA NA 0.080 0.020 NA NA 81.01 NA NA NA NA

Biotechnology & Drugs NTOL Natrol, Inc. NASD Healthcare 37.620 NA NA 2.80 1.01 49.12 13.430 6.600 39.38 0.260 50.88 -6 NA 0.22 3.15

Biotechnology & Drugs NAII Natural Alternatives International, Inc. NASD Healthcare 49.110 NA NA 8.21 1.86 18.41 5.980 4.600 7.27 -1.070 23.10 5 NA 0.20 2.16

Biotechnology & Drugs NAWL Naturewell, Inc. OTC Healthcare 0.970 NA NA 0.01 NA NA 118.220 72.100 0.00 0.000 39.01 0 NA NA 0.02

Biotechnology & Drugs NTY NBTY, Inc. NYSE Healthcare 1,678.960 1.21 14.00 24.99 2.40 17.69 67.190 56.600 76.53 -1.700 15.76 0 NA 0.42 2.76

Biotechnology & Drugs NEOG Neogen Corporation NASD Healthcare 114.990 1.19 16.50 14.11 2.16 21.67 8.150 7.000 27.61 -0.100 14.11 -13 NA 0.04 5.69

Biotechnology & Drugs NEOL NeoPharm, Inc. NASD Healthcare 235.490 NA NA 10.00 4.87 NA 23.550 18.800 75.26 1.160 20.17 5 NA NA 7.10

Biotechnology & Drugs NEOP Neoprobe Corporation OTC Healthcare 19.920 NA NA 0.34 2.52 NA 58.590 53.400 0.03 -0.340 8.85 6 NA 0.03 10.44

Biotechnology & Drugs NERX NeoRx Corporation NASD Healthcare 27.040 NA NA 0.79 1.39 NA 34.230 31.700 8.64 0.910 7.39 1 NA 0.21 7.09

Biotechnology & Drugs NTEC Neose Technologies, Inc. NASD Healthcare 126.700 NA NA 3.87 1.58 NA 32.780 30.800 60.15 4.070 6.05 3 NA 0.22 5.93

Biotechnology & Drugs NTII Neurobiological Tech. NASD Healthcare 84.950 NA NA 3.14 4.55 NA 27.050 24.000 25.02 -0.160 11.29 3 NA NA 2.03

Biotechnology & Drugs NRMX Neurochem Inc. (USA) NASD Healthcare 381.300 NA NA 11.03 5.03 NA 34.570 21.800 21.76 0.920 36.94 0 NA 0.11 6.28

Biotechnology & Drugs NBIX Neurocrine Biosciences, Inc. NASD Healthcare 1,677.810 -1.67 25.00 45.79 4.48 NA 36.640 35.500 86.09 -2.100 3.11 -2 NA 0.17 5.96

Biotechnology & Drugs NRGN Neurogen Corporation NASD Healthcare 238.280 NA NA 6.90 1.68 NA 34.530 25.900 36.90 0.020 25.00 -3 NA 0.09 16.02

Biotechnology & Drugs NRGX Neurologix, Inc. OTC Healthcare 52.510 NA NA 2.00 9.33 NA 26.250 15.800 27.71 0.380 39.82 -13 NA 0.01 9.03

Biotechnology & Drugs NRPH New River Pharmaceuticals, Inc. NASD Healthcare 513.120 NA NA 28.78 34.47 NA 17.830 4.200 17.39 0.230 76.44 -3 NA NA 25.14

Biotechnology & Drugs BBAL New York Health Care, Inc. OTC Healthcare 26.270 NA NA 0.80 4.50 NA 32.840 32.500 NA NA 1.04 NA NA NA 1.09

Biotechnology & Drugs NEXM NexMed, Inc. NASD Healthcare 65.310 NA NA 1.26 9.57 NA 51.830 50.000 20.68 -0.010 3.53 6 NA 0.98 3.12

Biotechnology & Drugs NTMD NitroMed, Inc. NASD Healthcare 711.430 -0.51 21.95 23.50 6.06 NA 30.270 16.900 66.24 0.280 44.18 0 NA 0.00 7.24

Biotechnology & Drugs NASI North American Scientific, Inc. NASD Healthcare 44.400 -0.17 20.00 2.71 0.76 NA 16.390 13.000 45.70 -0.460 20.70 3 NA NA 1.57

Biotechnology & Drugs NFLD Northfield Laboratories NASD Healthcare 384.600 NA NA 14.38 3.79 NA 26.750 24.000 26.63 2.270 10.26 -2 NA NA 55.02

Biotechnology & Drugs NWBT Northwest Biotherapeutics OTC Healthcare 3.050 NA NA 0.16 NA NA 19.080 18.900 0.00 0.000 0.93 0 NA NA 0.04

Biotechnology & Drugs NVAX Novavax, Inc. NASD Healthcare 39.410 NA NA 0.99 1.61 NA 39.810 35.100 10.45 -0.950 11.83 0 NA 1.51 2.21

Biotechnology & Drugs NOVN Noven Pharmaceuticals, Inc. NASD Healthcare 421.700 1.12 24.00 17.90 3.24 38.58 23.560 22.600 83.12 -0.200 4.07 0 NA 0.00 3.42

Biotechnology & Drugs NVO Novo Nordisk A/S (ADR) NYSE Healthcare 16,996.870 1.77 10.46 51.18 NA 20.80 332.110 236.600 3.15 3.400 28.76 0 1.67 NA NA

Biotechnology & Drugs NVGN Novogen Limited (ADR) NASD Healthcare 362.710 NA NA 18.75 8.47 NA 19.340 16.240 3.75 0.310 16.05 0 NA 0.02 10.04

Biotechnology & Drugs NPSP NPS Pharmaceuticals, Inc. NASD Healthcare 492.500 NA NA 12.69 NA NA 38.810 38.000 87.56 -0.970 2.09 -5 NA NA 7.41

Biotechnology & Drugs NPHCE Nutra Pharma Corp. OTC Healthcare 19.370 NA NA 0.30 NA NA 64.570 57.500 NA NA 10.95 NA NA NA 0.03

Biotechnology & Drugs NUTR Nutraceutical Int'l Corp. NASD Healthcare 156.670 NA NA 13.51 2.01 12.85 11.600 11.100 73.27 0.120 4.29 0 NA 0.09 3.16

Biotechnology & Drugs NXXI Nutrition 21, Inc. NASD Healthcare 23.260 NA NA 0.61 1.55 NA 38.140 32.000 4.23 0.910 16.09 2 NA NA 3.45

Biotechnology & Drugs NUVO Nuvelo, Inc. NASD Healthcare 341.190 NA NA 8.12 3.42 NA 42.020 41.200 63.15 8.650 1.95 2 NA 0.15 5.22

Biotechnology & Drugs NYMX Nymox Pharmaceutical Corporation NASD Healthcare 63.960 NA NA 2.49 84.50 NA 25.690 12.300 0.53 0.030 52.12 0 NA 0.66 0.14

Biotechnology & Drugs ONCY Oncolytics Biotech, Inc. (USA) NASD Healthcare 102.960 NA NA 3.15 3.21 NA 32.680 32.400 10.86 0.300 0.87 0 NA 0.00 27.76

Biotechnology & Drugs ONCR Oncor, Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 33.550 24.500 0.15 -0.020 26.98 0 NA NA 5.83

Biotechnology & Drugs ONXX Onyx Pharmaceuticals, Inc. NASD Healthcare 945.090 -0.95 11.00 26.78 5.77 NA 35.290 32.800 89.02 -0.380 7.06 0 NA 0.12 12.21

Biotechnology & Drugs ONI Oragenics, Inc. AMEX Healthcare 25.840 NA NA 1.77 8.73 NA 14.600 7.300 1.27 0.000 49.99 2 NA 0.12 5.50

Biotechnology & Drugs ORCH Orchid Cellmark, Inc. NASD Healthcare 271.070 5.75 30.00 11.08 4.73 NA 24.460 24.400 NA NA 0.26 NA NA 0.00 3.52

Biotechnology & Drugs ORGT OrganiTECH USA, Inc. OTC Healthcare 4.240 NA NA 0.20 NA NA 21.220 6.800 NA NA 67.95 NA NA NA 0.34

Biotechnology & Drugs OSCI Oscient Pharmaceuticals Corporation NASD Healthcare 200.610 NA NA 2.62 2.28 NA 76.570 67.800 39.83 1.380 11.45 -19 NA 1.99 4.85

Biotechnology & Drugs OSIP OSI Pharmaceuticals, Inc. NASD Healthcare 2,281.400 -1.60 15.00 44.50 4.47 NA 51.270 51.000 95.00 -0.860 0.52 -28 NA 0.30 15.29

Biotechnology & Drugs OXGN OXiGENE, Inc. NASD Healthcare 88.640 NA NA 4.42 2.17 NA 20.050 19.400 14.55 0.810 3.26 6 NA NA 15.28

Biotechnology & Drugs OXIS OXIS International, Inc. OTC Healthcare 12.990 NA NA 0.31 2.26 NA 41.910 11.100 0.12 -0.040 73.51 0 NA 0.03 6.03

Biotechnology & Drugs PBME Pacific Biometrics, Inc. OTC Healthcare 13.580 NA NA 1.01 NA NA 13.450 7.400 0.00 0.000 44.97 -1 NA NA 1.50

Biotechnology & Drugs PHLI PacificHealth Laboratories, Inc. OTC Healthcare 2.660 NA NA 0.26 NA NA 10.240 8.000 0.00 0.000 21.85 -1 NA 0.97 1.12

Biotechnology & Drugs PTIE Pain Therapeutics, Inc. NASD Healthcare 276.230 NA NA 6.32 3.27 NA 43.710 30.000 45.70 -0.260 31.36 0 NA NA 11.11

Biotechnology & Drugs PTN Palatin Technologies, Inc. AMEX Healthcare 108.640 NA NA 2.01 7.85 NA 54.050 54.000 19.84 -2.020 0.09 3 NA 0.00 2.69

Biotechnology & Drugs PGNT Paligent Inc. OTC Healthcare 2.440 NA NA 0.08 NA 12.50 32.490 14.900 0.00 -0.030 54.14 0 NA NA 0.47

Biotechnology & Drugs PRX Par Pharmaceutical Companies, Inc NYSE Healthcare 1,107.810 0.86 22.10 32.40 2.62 ####### 34.190 34.100 95.00 0.730 0.27 1 NA 0.48 3.53

Biotechnology & Drugs PRLN Paracelsian, Inc. OTC Healthcare 0.120 NA NA 0.01 NA NA 23.950 16.000 0.69 0.000 33.21 0 NA NA 0.03

Biotechnology & Drugs PRXL PAREXEL International Corporation NASD Healthcare 524.600 1.95 14.33 20.10 1.97 23.51 26.100 26.000 95.00 -0.100 0.38 0 NA 0.01 1.77

Biotechnology & Drugs PPCO Penwest Pharmaceuticals NASD Healthcare 261.160 NA NA 12.02 3.61 NA 21.730 21.600 75.35 -0.930 0.59 0 NA 0.00 19.91

Biotechnology & Drugs PPHM Peregrine Pharmaceuticals NASD Healthcare 155.780 NA NA 1.03 14.85 NA 151.240 142.600 12.69 -1.230 5.71 4 NA 0.07 3.02

Biotechnology & Drugs PRGO Perrigo Company NASD Healthcare 1,302.450 1.51 10.00 13.88 2.14 NA 93.840 65.200 66.72 2.200 30.52 -1 1.15 1.16 1.81

Biotechnology & Drugs PHFR Pharmaceutical Formulations, Inc. OTC Healthcare 14.650 NA NA 0.17 NA NA 86.160 83.300 NA NA 3.32 NA NA NA 0.70





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 08Jul05 24 of 45 10/24/2011 3:30 PM

BioTech Industry 08Jul05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs PPDI NASD

Pharmaceutical Product Development, Inc. Healthcare 2,745.880 1.39 18.11 48.30 4.08 25.16 56.850 48.300 79.38 0.130 15.04 -6 NA 0.01 1.73

Biotechnology & Drugs PCOP Pharmacopeia Drug Discovery, Inc. NASD Healthcare 49.740 NA NA 4.00 1.27 NA 12.440 12.200 71.08 -0.590 1.90 2 NA NA 3.60

Biotechnology & Drugs PCYC Pharmacyclics, Inc. NASD Healthcare 152.830 NA NA 7.74 1.97 NA 19.750 19.500 71.60 0.420 1.24 0 NA NA 18.81

Biotechnology & Drugs PFTR PharmaFrontiers Corp. OTC Healthcare 26.340 NA NA 2.50 1.14 NA 10.530 9.900 0.00 0.000 6.03 -3 NA 0.19 0.34

Biotechnology & Drugs PPRT PharmaPrint Inc. OTC Healthcare 0.010 NA NA 0.00 NA NA 23.980 22.500 NA NA 6.19 NA NA NA 0.06

Biotechnology & Drugs PHRM Pharmion Corporation NASD Healthcare 756.830 1.23 42.00 23.78 2.14 NA 31.830 26.400 65.59 0.250 17.05 4 NA NA 5.36

Biotechnology & Drugs PARS Pharmos Corporation NASD Healthcare 44.900 NA NA 2.36 0.83 NA 19.030 18.600 0.00 0.000 2.24 0 NA 0.00 21.34

Biotechnology & Drugs PLTT Pilot Therapeutics Holdings, Inc. OTC Healthcare 0.810 NA NA 0.07 NA NA 11.540 2.600 NA NA 77.48 NA NA NA 0.25

Biotechnology & Drugs PLRS Pluristem Life Systems, Inc. OTC Healthcare 12.720 NA NA 0.20 10.54 NA 63.600 47.100 NA NA 25.95 NA NA 0.00 7.01

Biotechnology & Drugs POTP Point Therapeutics, Inc. OTC Healthcare 91.690 NA NA 4.09 3.93 NA 22.420 20.400 29.25 1.920 9.00 0 NA NA 8.54

Biotechnology & Drugs POLXF Polydex Pharmaceuticals Limited NASD Healthcare 16.330 NA NA 5.35 2.02 NA 3.050 2.700 0.92 0.000 11.53 0 NA 0.12 3.39

Biotechnology & Drugs PROAQ Polymer Research Corp. of America OTC Healthcare 1.020 NA NA 0.48 3.27 NA 2.130 0.900 0.14 0.000 57.73 0 NA 6.88 0.69

Biotechnology & Drugs PWRM Power3 Medical Products, Inc. OTC Healthcare 13.070 NA NA 0.21 NA NA 62.250 9.300 0.00 0.000 85.06 0 NA NA 0.10

Biotechnology & Drugs POZN POZEN Inc. NASD Healthcare 246.360 NA NA 8.52 9.37 NA 28.920 25.000 40.13 -2.050 13.54 3 NA NA 3.53

Biotechnology & Drugs PRAI PRA International NASD Healthcare 643.160 1.54 15.00 28.74 4.07 24.40 22.380 12.000 30.82 0.920 46.38 -11 NA NA 1.14

Biotechnology & Drugs PRCS Praecis Pharmaceuticals NASD Healthcare 28.310 NA NA 0.54 0.28 NA 52.420 46.100 45.66 -3.510 12.06 1 NA 0.32 11.01

Biotechnology & Drugs PRAN Prana Biotechnology Limited (ADR) NASD Healthcare 15.510 NA NA 1.22 0.56 NA 12.710 11.530 15.95 -0.060 9.31 0 NA NA 18.98

Biotechnology & Drugs PBIO Pressure BioSciences, Inc. NASD Healthcare 6.790 NA NA 2.80 0.77 NA 2.420 2.400 2.19 -0.270 0.99 6 NA NA 6.53

Biotechnology & Drugs PGLAF Progen Industries Limited (USA) NASD Healthcare 78.480 NA NA 2.21 6.06 NA 35.510 33.000 0.94 0.320 7.07 0 NA 0.01 11.71

Biotechnology & Drugs PGNX Progenics Pharmaceuticals, Inc. NASD Healthcare 440.380 NA NA 22.50 18.09 NA 19.570 16.300 61.63 0.690 16.72 -16 NA NA 2.67

Biotechnology & Drugs PRW Pro-Pharmaceuticals, Inc. AMEX Healthcare 77.580 NA NA 2.84 8.91 NA 27.320 22.300 3.31 0.280 18.36 2 NA NA 11.21

Biotechnology & Drugs PDLI Protein Design Labs, Inc. NASD Healthcare 2,257.150 -1.49 66.50 21.29 4.79 NA 106.020 103.000 81.46 6.680 2.85 -33 NA 1.08 3.10

Biotechnology & Drugs PPTI Protein Polymer Technologies, Inc. OTC Healthcare 31.040 NA NA 0.55 NA NA 56.430 30.300 0.01 0.000 46.31 0 NA NA 0.07

Biotechnology & Drugs PPMD Protide Pharmaceuticals OTC Healthcare 0.850 NA NA 0.21 3.54 NA 4.030 3.400 NA NA 15.61 NA NA 0.30 2.61

Biotechnology & Drugs PVLS Provalis PLC (ADR) NASD Healthcare 18.960 NA NA 1.63 0.69 NA 11.630 9.650 0.03 0.000 16.99 0 NA NA 1.88

Biotechnology & Drugs PVCT Provectus Pharmaceuticals, Inc. OTC Healthcare 11.650 NA NA 0.70 1.33 NA 16.640 11.000 0.15 0.000 33.91 0 NA 0.20 0.32

Biotechnology & Drugs PMD Psychemedics Corp. AMEX Healthcare 68.400 NA NA 13.25 9.61 20.87 5.160 5.000 30.84 0.300 3.14 -5 2.42 NA 3.32

Biotechnology & Drugs PURW Pure World, Inc. NASD Healthcare 34.730 NA NA 4.30 2.00 30.71 8.080 4.300 6.50 0.010 46.76 0 NA 0.11 3.43

Biotechnology & Drugs QLTI QLT Inc. (USA) NASD Healthcare 1,023.540 0.70 21.50 10.91 1.16 NA 93.820 93.100 54.45 3.380 0.76 4 NA 0.20 17.16

Biotechnology & Drugs QSC Questcor Pharmaceuticals AMEX Healthcare 32.660 NA NA 0.62 7.91 NA 52.680 44.200 8.83 -0.310 16.09 2 NA 0.38 1.34

Biotechnology & Drugs REGN Regeneron Pharmaceuticals, Inc. NASD Healthcare 533.150 NA NA 9.50 2.87 NA 56.120 36.300 47.96 -1.190 35.32 -9 NA 1.08 12.36

Biotechnology & Drugs RGN RegeneRx Biopharmaceut. AMEX Healthcare 122.210 NA NA 3.39 19.18 NA 36.050 29.200 2.92 -0.010 19.00 6 NA NA 15.86

Biotechnology & Drugs RNVS Renovis, Inc. NASD Healthcare 378.240 NA NA 15.30 5.05 NA 24.720 19.300 37.51 1.910 21.93 -19 NA 0.06 9.52

Biotechnology & Drugs RGEN Repligen Corporation NASD Healthcare 59.890 NA NA 1.99 2.47 NA 30.090 28.600 11.99 0.930 4.96 3 NA NA 5.90

Biotechnology & Drugs RIGL Rigel Pharmaceuticals, Inc. NASD Healthcare 423.070 NA NA 21.29 9.44 NA 19.870 18.100 78.42 1.250 8.92 0 NA 0.06 5.09

Biotechnology & Drugs STCX SalesTactix, Inc. OTC Healthcare 0.340 NA NA 0.05 NA NA 6.840 4.400 NA NA 35.63 NA NA NA NA

Biotechnology & Drugs SLXP Salix Pharmaceuticals Ltd NASD Healthcare 723.620 0.67 46.48 19.74 7.96 61.69 36.660 35.300 91.68 1.220 3.71 0 NA NA 5.17

Biotechnology & Drugs LIV Samaritan Pharmaceuticals, Inc. AMEX Healthcare 59.980 NA NA 0.45 12.14 NA 133.280 125.500 0.57 0.020 5.84 0 NA NA 19.48

Biotechnology & Drugs SGMO Sangamo Biosciences, Inc. NASD Healthcare 96.950 NA NA 3.82 3.33 NA 25.380 15.300 32.73 -0.500 39.72 -9 NA NA 17.30

Biotechnology & Drugs SGNCE Sanguine Corporation OTC Healthcare 12.000 NA NA 0.15 39.61 5.77 80.010 39.200 0.00 0.000 51.01 -1 NA NA 9.66

Biotechnology & Drugs SNY Sanofi-Aventis (ADR) NYSE Healthcare 117,880.090 1.44 10.30 41.76 2.78 NA 2,822.810 2,145.400 4.36 20.940 24.00 0 1.83 NA NA

Biotechnology & Drugs SNTS Santarus, Inc. NASD Healthcare 146.720 -0.05 30.00 4.03 2.01 NA 36.410 33.200 44.49 -1.060 8.81 3 NA 0.15 4.77

Biotechnology & Drugs SVNT Savient Pharmaceuticals, Inc. NASD Healthcare 272.890 NA NA 4.49 1.80 NA 60.780 57.400 43.53 2.150 5.56 6 NA 0.03 3.00

Biotechnology & Drugs SCLN SciClone Pharmaceuticals NASD Healthcare 207.260 NA NA 4.63 3.86 NA 44.760 43.800 24.61 -0.620 2.15 62 NA 0.10 5.51

Biotechnology & Drugs DDD SCOLR Pharma Inc. AMEX Healthcare 131.500 NA NA 3.81 6.17 NA 34.510 31.800 6.57 1.280 7.86 5 NA 0.00 26.28

Biotechnology & Drugs SGEN Seattle Genetics, Inc. NASD Healthcare 250.570 NA NA 5.94 2.59 NA 42.180 28.300 50.06 -0.570 32.91 50 NA NA 4.43

Biotechnology & Drugs STLT Select Therapeutics Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 17.560 15.000 NA NA 14.58 NA NA NA NA

Biotechnology & Drugs SNT Senesco Technologies, Inc. AMEX Healthcare 26.960 NA NA 1.58 6.72 NA 17.060 14.900 12.35 0.160 12.68 6 NA NA 6.67

Biotechnology & Drugs SNTKY Senetek PLC (ADR) OTC Healthcare 12.800 NA NA 0.21 NA NA 60.960 60.900 0.05 -0.010 0.10 0 NA NA 2.50

Biotechnology & Drugs SNMX Senomyx Inc. NASD Healthcare 457.240 NA NA 17.96 12.68 NA 25.460 21.100 62.08 1.630 17.12 -8 NA NA 9.79

Biotechnology & Drugs SGHL Sentigen Holding Corp. NASD Healthcare 35.950 NA NA 4.81 2.52 NA 7.470 5.000 1.07 0.000 33.11 -5 NA 0.06 6.02

Biotechnology & Drugs SEPR Sepracor Inc. NASD Healthcare 6,038.820 NA NA 57.64 NA NA 104.770 96.600 95.00 -4.370 7.80 -13 NA NA 4.79

Biotechnology & Drugs SQNM Sequenom, Inc. NASD Healthcare 42.450 NA NA 1.05 1.38 NA 40.430 39.100 10.50 -0.140 3.29 0 NA 0.24 2.47

Biotechnology & Drugs SRLS SeraCare Life Sciences NASD Healthcare 200.650 1.07 20.00 14.35 2.86 24.36 13.980 11.800 13.09 0.060 15.61 -2 NA 0.60 2.72

Biotechnology & Drugs SERO Serologicals Corporation NASD Healthcare 790.860 1.28 17.67 22.74 1.87 41.96 34.780 34.300 NA NA 1.37 -9 NA 0.31 4.52

Biotechnology & Drugs SRA Serono S.A. (ADR) NYSE Healthcare 9,497.140 1.34 13.43 16.31 5.19 NA 582.290 220.000 1.13 -0.010 62.22 0 2.29 0.36 1.42

Biotechnology & Drugs SFCC SFBC International, Inc. NASD Healthcare 705.340 0.72 27.00 38.59 2.46 28.86 18.280 16.900 81.44 3.740 7.54 -5 NA 0.71 2.75

Biotechnology & Drugs SHPH Shaman Pharmaceuticals Inc. OTC Healthcare 0.010 NA NA 0.00 NA NA 103.460 46.600 0.11 0.000 54.96 0 NA NA 0.11

Biotechnology & Drugs SHPGY Shire Pharmaceuticals Group plc (ADR) NASD Healthcare 5,521.010 1.21 14.30 33.45 2.42 21.00 165.050 160.000 22.95 2.230 3.06 0 0.51 0.01 4.72

Biotechnology & Drugs SIGA SIGA Technologies, Inc. NASD Healthcare 25.240 NA NA 1.03 7.44 NA 24.500 16.800 5.40 0.100 31.43 0 NA 0.00 0.81

Biotechnology & Drugs SVA Sinovac Biotech Ltd. AMEX Healthcare 110.840 NA NA 2.95 8.17 NA 37.570 15.800 0.08 0.010 57.95 0 NA 0.22 1.27

Biotechnology & Drugs RNAI Sirna Therapeutics, Inc. NASD Healthcare 78.620 NA NA 1.89 2.91 NA 41.600 17.500 47.05 -0.740 57.93 0 NA 0.00 8.23

Biotechnology & Drugs SKYE SkyePharma plc (ADR) NASD Healthcare 627.380 NA NA 10.08 5.68 NA 62.240 51.040 0.77 0.180 18.00 0 NA 1.31 0.78

Biotechnology & Drugs SLXA Solexa, Inc. NASD Healthcare 129.820 NA NA 6.50 0.57 NA 19.970 10.800 6.02 1.200 45.93 1 NA 0.11 0.81

Biotechnology & Drugs SNUS Sonus Pharmaceuticals, Inc. NASD Healthcare 72.460 NA NA 3.39 5.05 NA 21.370 21.100 17.13 -0.590 1.26 0 NA 0.01 6.76





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 08Jul05 25 of 45 10/24/2011 3:30 PM

BioTech Industry 08Jul05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs DIAGF Spectral Diagnostics, Inc (USA) NASD Healthcare 10.330 NA NA 0.52 1.73 NA 19.860 17.900 0.00 0.000 9.87 0 NA 1.17 3.34

Biotechnology & Drugs SPPI Spectrum Pharmaceuticals, Inc. NASD Healthcare 72.510 NA NA 4.72 2.23 NA 15.350 14.000 25.43 -0.190 8.81 6 NA NA 10.02

Biotechnology & Drugs SLXCF Stellar Pharmaceuticals Inc. (USA) OTC Healthcare 27.750 NA NA 1.20 8.60 NA 23.130 17.600 NA NA 23.90 NA NA NA 6.63

Biotechnology & Drugs STEM StemCells, Inc. NASD Healthcare 294.410 NA NA 4.71 8.64 NA 62.510 61.300 7.70 -0.010 1.93 0 NA 0.06 13.70

Biotechnology & Drugs STGN Stratagene Corporation NASD Healthcare 190.300 1.37 15.00 8.63 3.27 21.96 22.050 8.800 14.11 -0.080 60.09 -4 NA 0.10 2.03

Biotechnology & Drugs SUPG SuperGen, Inc. NASD Healthcare 279.430 NA NA 5.46 4.16 NA 51.180 46.600 40.08 1.550 8.94 0 NA NA 4.41

Biotechnology & Drugs SWME Swiss Medica, Inc. OTC Healthcare 24.100 NA NA 0.28 5.61 NA 87.650 74.500 0.03 0.030 15.01 0 NA 0.12 3.35

Biotechnology & Drugs SYMBA Symbollon Pharmaceuticals, Inc. OTC Healthcare 7.670 NA NA 1.15 11.04 NA 6.670 5.600 0.00 0.000 16.03 0 NA NA 2.50

Biotechnology & Drugs SBIO Synbiotics Corporation OTC Healthcare 2.200 NA NA 0.07 1.04 NA 33.820 13.900 0.73 0.000 58.90 0 NA 1.00 1.73

Biotechnology & Drugs SYBD Synthetic Blood Int'l Inc OTC Healthcare 27.240 NA NA 0.22 18.83 NA 125.530 123.100 0.02 -0.030 1.94 0 NA NA 3.21

Biotechnology & Drugs TNOX Tanox, Inc. NASD Healthcare 580.390 NA NA 12.95 2.75 NA 44.820 25.000 55.82 -1.190 44.22 0 NA 0.02 17.08

Biotechnology & Drugs TPPH Tapestry Pharmaceuticals, Inc. NASD Healthcare 17.080 NA NA 0.51 0.73 NA 33.490 30.500 11.48 -0.230 8.93 2 NA 0.15 8.36

Biotechnology & Drugs TGEN Targeted Genetics Corp. NASD Healthcare 68.500 NA NA 0.80 1.52 NA 85.630 60.100 5.24 -0.090 29.81 0 NA 0.25 7.62

Biotechnology & Drugs TARO Taro Pharmaceutical Industries Ltd. NASD Healthcare 825.890 1.02 22.50 28.31 2.22 172.62 29.170 26.900 61.91 -0.690 7.79 0 NA 0.69 2.47

Biotechnology & Drugs TCPI TCPI, Inc. OTC Healthcare 0.090 NA NA 0.00 0.01 NA 96.910 91.100 NA NA 5.99 NA NA 0.01 0.64

Biotechnology & Drugs TECH Techne Corporation NASD Healthcare 1,838.230 2.18 13.00 47.81 7.46 32.52 38.450 36.100 84.75 -0.300 6.11 -5 NA 0.06 6.10

Biotechnology & Drugs TELK Telik, Inc. NASD Healthcare 880.740 -0.18 54.00 16.95 3.54 NA 51.960 51.600 89.59 5.430 0.70 2 NA 0.01 14.94

Biotechnology & Drugs TRCA Tercica, Inc. NASD Healthcare 299.100 NA NA 9.47 2.92 NA 31.580 16.100 36.28 4.230 49.03 5 NA NA 18.47

Biotechnology & Drugs TEVA NASD

Teva Pharmaceutical Industries Ltd (ADR) Healthcare 18,646.320 0.94 20.56 30.80 3.52 20.41 605.400 557.000 52.13 11.210 8.00 0 0.89 0.38 1.94

Biotechnology & Drugs IMNR The Immune Response Corp. NASD Healthcare 33.210 NA NA 0.68 NA NA 48.840 29.500 4.78 0.510 39.60 0 NA 38.55 1.83

Biotechnology & Drugs MDCO The Medicines Company NASD Healthcare 1,150.740 1.08 42.67 23.29 6.49 76.61 49.410 44.400 95.00 -2.650 10.14 -5 NA NA 5.47

Biotechnology & Drugs QGLY The Quigley Corporation NASD Healthcare 104.120 NA NA 8.93 4.78 159.46 11.660 9.100 3.21 0.140 21.96 0 NA 0.13 3.85

Biotechnology & Drugs TGX Theragenics Corporation NYSE Healthcare 103.380 NA NA 3.24 0.71 NA 31.910 31.300 43.54 -2.410 1.91 1 NA NA 27.63

Biotechnology & Drugs THRX Theravance, Inc. NASD Healthcare 904.680 NA NA 16.98 5.60 NA 53.280 6.200 26.97 2.770 88.36 0 NA 0.02 6.62

Biotechnology & Drugs TWTI Third Wave Technologies NASD Healthcare 174.500 -0.60 25.00 4.24 3.01 NA 41.150 34.800 57.81 -3.570 15.44 9 NA 0.18 3.28

Biotechnology & Drugs THLD Threshold Pharmaceuticals, Inc. NASD Healthcare 259.500 NA NA 8.44 4.69 NA 30.750 5.300 23.82 7.330 82.76 7 NA 0.01 7.48

Biotechnology & Drugs TBV Tiens Biotech Group (USA), Inc. AMEX Healthcare 413.730 NA NA 5.80 6.26 15.59 71.330 4.300 0.00 0.000 93.97 0 NA 0.16 10.07

Biotechnology & Drugs TTP Titan Pharmaceuticals AMEX Healthcare 60.810 NA NA 1.88 2.22 NA 32.350 31.700 21.48 0.110 2.00 0 NA NA 7.16

Biotechnology & Drugs TRGNY Transgene (ADR) NASD Healthcare 86.840 NA NA 2.85 5.11 NA 30.470 7.270 0.00 0.000 76.13 0 NA NA 3.14

Biotechnology & Drugs TKTX Transkaryotic Therapies NASD Healthcare 1,298.710 NA NA 37.09 7.44 NA 35.020 28.000 94.51 6.910 20.03 0 NA 0.54 5.32

Biotechnology & Drugs TRMS Trimeris, Inc. NASD Healthcare 250.450 NA NA 11.41 9.83 NA 21.950 17.600 94.60 0.800 19.82 0 NA NA 8.35

Biotechnology & Drugs TRIB Trinity Biotech plc (ADR) NASD Healthcare 93.010 NA NA 6.61 0.79 17.76 14.080 12.630 NA NA 10.31 NA NA 0.18 3.43

Biotechnology & Drugs TMGU Trinity Medical Group USA, Inc. OTC Healthcare 0.200 NA NA 0.01 NA NA 19.520 9.900 NA NA 49.28 NA NA NA 0.34

Biotechnology & Drugs TRPS Tripos, Inc. NASD Healthcare 34.810 NA NA 3.45 1.08 575.00 10.090 9.600 45.01 -0.190 4.86 0 NA 0.47 0.97

Biotechnology & Drugs UGNE Unigene Laboratories OTC Healthcare 136.080 NA NA 1.66 NA NA 81.970 76.900 0.58 0.270 6.19 0 NA NA 0.11

Biotechnology & Drugs UTHR United Therapeutics Corporation NASD Healthcare 1,208.470 1.11 33.50 53.41 5.93 51.21 22.630 22.200 95.00 -0.600 1.88 -62 NA 0.00 10.01

Biotechnology & Drugs UG United-Guardian, Inc. AMEX Healthcare 39.950 NA NA 8.10 2.89 15.25 4.930 2.800 11.88 0.010 43.24 -1 2.22 NA 12.82

Biotechnology & Drugs VITX V.I. Technologies, Inc. NASD Healthcare 209.360 NA NA 5.30 10.80 NA 39.500 21.300 4.65 1.830 46.08 1 NA 0.07 2.69

Biotechnology & Drugs VRX Valeant Pharmaceuticals International NYSE Healthcare 1,624.120 2.63 29.00 17.55 3.20 NA 92.540 92.100 95.00 9.220 0.48 0 1.77 1.56 3.17

Biotechnology & Drugs VLTS Valentis, Inc. NASD Healthcare 33.460 NA NA 2.55 3.23 NA 13.120 9.800 39.95 0.120 25.32 -2 NA NA 4.76

Biotechnology & Drugs VAPH Vaso Active Pharmaceuticals, Inc. OTC Healthcare 7.750 NA NA 0.75 9.68 NA 10.330 5.700 0.53 0.000 44.82 0 NA NA 2.20

Biotechnology & Drugs VXGN VaxGen, Inc. OTC Healthcare 302.940 NA NA 12.08 11.35 NA 25.080 24.600 31.43 0.540 1.91 0 NA 0.00 1.47

Biotechnology & Drugs VNLS Vernalis plc (ADR) NASD Healthcare 167.380 NA NA 2.15 7.49 NA 77.850 54.500 0.94 -1.270 29.99 0 NA 4.68 3.81

Biotechnology & Drugs VRTX Vertex Pharmaceuticals NASD Healthcare 1,579.270 NA NA 16.99 NA NA 92.950 89.600 68.39 0.650 3.61 -14 NA NA 2.36

Biotechnology & Drugs VIAC Viacell, Inc. NASD Healthcare 411.290 NA NA 10.89 9.71 NA 37.770 7.500 11.35 4.290 80.14 0 NA 0.05 5.00

Biotechnology & Drugs VICL Vical Incorporated NASD Healthcare 106.300 NA NA 4.52 1.41 NA 23.520 21.700 33.11 -0.310 7.73 0 NA 0.14 8.18

Biotechnology & Drugs MICU Vicuron Pharmaceuticals, Inc. NASD Healthcare 1,704.940 NA NA 27.98 8.09 NA 60.930 59.600 71.57 0.600 2.19 -4 NA 0.05 9.10

Biotechnology & Drugs VION Vion Pharmaceuticals, Inc. NASD Healthcare 153.520 NA NA 2.33 2.49 NA 65.890 64.200 56.41 6.640 2.56 0 NA NA 10.27

Biotechnology & Drugs VGNI Viragen International, Inc. OTC Healthcare 8.840 NA NA 0.12 3.45 NA 73.670 9.600 NA NA 86.97 NA NA 0.28 4.05

Biotechnology & Drugs VRA Viragen, Inc. AMEX Healthcare 26.700 NA NA 0.72 1.56 NA 37.090 36.300 5.95 0.100 2.13 4 NA 0.94 0.96

Biotechnology & Drugs VRAL Viral Genetics, Inc. OTC Healthcare 19.990 NA NA 0.22 5.52 NA 90.860 34.500 NA NA 62.03 NA NA 0.54 1.36

Biotechnology & Drugs VBAC Virbac Corporation OTC Healthcare 58.050 NA NA 2.60 3.58 NA 22.330 8.200 2.79 0.040 63.27 0 NA 1.70 0.65

Biotechnology & Drugs VLGC ViroLogic, Inc NASD Healthcare 302.830 NA NA 2.49 4.48 NA 121.620 121.000 57.96 6.420 0.51 -4 NA 0.06 7.57

Biotechnology & Drugs VPHM ViroPharma Incorporated NASD Healthcare 255.990 0.97 20.00 9.10 NA 36.99 28.130 27.600 45.99 0.600 1.89 34 NA NA 6.18

Biotechnology & Drugs PRH VitaCube Systems Holdings, Inc. AMEX Healthcare 12.870 NA NA 1.35 NA NA 9.530 5.100 NA NA 46.51 NA NA NA 0.41

Biotechnology & Drugs VTLV Vital Living, Inc. OTC Healthcare 5.580 NA NA 0.06 0.29 NA 101.390 61.800 0.81 -0.340 39.04 0 NA 0.15 0.25

Biotechnology & Drugs VVUS VIVUS, Inc. NASD Healthcare 163.660 NA NA 3.68 3.92 NA 44.470 43.100 45.67 4.270 3.09 3 NA 0.09 3.30

Biotechnology & Drugs VYRX Vyrex Corporation OTC Healthcare 0.850 NA NA 0.10 NA NA 8.490 7.300 NA NA 14.05 NA NA NA 0.15

Biotechnology & Drugs WPI Watson Pharmaceuticals, Inc. NYSE Healthcare 3,258.780 2.21 10.02 29.58 1.47 25.15 110.170 104.800 80.35 0.000 4.87 -5 NA 0.27 5.69

Biotechnology & Drugs WFHCQ Women First HealthCare OTC Healthcare 0.010 NA NA 0.00 NA NA 26.660 16.000 0.00 -0.090 39.98 0 NA NA 0.16

Biotechnology & Drugs XCYT Xcyte Therapies, Inc. NASD Healthcare 12.980 NA NA 0.66 0.35 NA 19.660 14.400 37.13 0.070 26.77 1 NA 0.11 5.46

Biotechnology & Drugs XKEM Xechem International, Inc OTC Healthcare 4.150 NA NA 0.02 NA NA 259.670 259.600 0.19 0.000 0.03 0 NA NA 0.14

Biotechnology & Drugs XNPT XenoPort, Inc. NASD Healthcare 198.020 NA NA 10.30 NA NA 19.230 5.000 NA NA 73.99 NA NA 0.04 5.53

Biotechnology & Drugs XNVA Xenova Group plc (ADR) NASD Healthcare 30.730 NA NA 0.71 0.57 NA 43.150 36.250 3.09 -1.510 16.00 0 NA NA 2.07

Biotechnology & Drugs XOMA XOMA Limited NASD Healthcare 152.670 NA NA 1.77 23.34 NA 86.250 76.800 25.40 -6.950 10.96 -2 NA 9.20 4.44





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BioTech Industry 08Jul05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs XTRN Xtrana, Inc. OTC Healthcare 2.650 NA NA 0.16 1.20 1.46 16.530 14.100 0.00 -0.020 14.72 0 NA NA 20.04

Biotechnology & Drugs YMI YM BioSciences Inc. (USA) AMEX Healthcare 97.370 NA NA 2.77 4.00 NA 35.150 34.400 15.51 0.260 2.14 0 NA NA 25.50

Biotechnology & Drugs ZILA Zila, Inc. NASD Healthcare 135.170 -0.67 32.50 2.95 3.18 NA 45.820 45.400 29.34 1.330 0.92 0 NA 0.09 2.27

Biotechnology & Drugs ZONA Zonagen, Incorporated NASD Healthcare 37.700 NA NA 3.74 1.66 NA 10.080 9.900 33.70 2.460 1.79 4 NA NA 20.31

Biotechnology & Drugs ZMTX ZymeTx, Inc. OTC Healthcare 0.430 NA NA 0.05 NA NA 8.610 6.600 0.00 0.000 23.31 0 NA NA 0.20

Biotechnology & Drugs ZGEN ZymoGenetics, Inc. NASD Healthcare 1,081.020 -0.79 15.00 18.70 4.13 NA 57.810 29.200 27.56 0.230 49.49 -9 NA NA 9.21

Major Drugs ABT Abbott Laboratories NYSE Healthcare 76,525.910 1.99 9.88 49.35 5.40 23.82 1,550.680 1,447.900 63.20 25.500 6.63 0 2.23 0.51 1.41

Major Drugs ACL Alcon, Inc. NYSE Healthcare 34,405.470 1.97 17.43 112.41 14.49 37.53 306.070 73.500 22.24 4.330 75.99 0 0.88 0.45 1.51

Major Drugs ALLI Allion Healthcare, Inc. NASD Healthcare 212.330 NA NA 17.85 4.70 NA 11.890 11.890 NA NA 0.00 NA NA 0.87 0.57

Major Drugs APNS Applied Neurosolutions, Inc. OTC Healthcare 27.320 NA NA 0.30 9.82 74.50 91.670 84.000 6.86 0.100 8.37 -9 NA 0.00 5.36

Major Drugs AZN AstraZeneca PLC (ADR) NYSE Healthcare 68,514.250 1.37 12.44 41.65 5.03 17.07 1,645.000 1,628.600 8.04 2.310 1.00 0 3.10 0.08 1.86

Major Drugs BAY Bayer AG (ADR) NYSE Healthcare 23,845.580 1.78 7.00 32.65 1.91 24.87 730.340 723.000 3.81 1.510 1.01 0 2.16 0.90 1.67

Major Drugs BMY Bristol Myers Squibb Co. NYSE Healthcare 48,680.500 5.87 3.00 24.91 5.29 25.14 1,954.260 1,940.410 67.54 41.230 0.71 0 4.50 0.83 1.61

Major Drugs LLY Eli Lilly & Co. NYSE Healthcare 63,736.490 1.89 10.38 56.25 5.50 28.57 1,133.090 978.300 68.96 4.930 13.66 -21 2.70 0.40 2.09

Major Drugs GSK GlaxoSmithKline plc (ADR) NYSE Healthcare 137,320.410 2.07 8.18 48.24 14.25 28.41 2,846.610 2,448.100 9.55 3.610 14.00 0 3.15 1.04 1.21

Major Drugs JNJ Johnson & Johnson NYSE Healthcare 191,139.440 1.66 11.20 64.28 5.68 21.63 2,973.540 2,943.800 65.32 52.730 1.00 -4 2.05 0.08 2.22

Major Drugs MRK Merck & Co., Inc. NYSE Healthcare 68,296.990 -4.94 -2.43 31.00 3.87 12.44 2,203.130 2,181.100 61.74 76.810 1.00 -4 4.90 0.41 1.45

Major Drugs NVD Novadel Pharma Inc AMEX Healthcare 47.060 NA NA 1.16 10.82 NA 40.570 26.000 6.77 -0.110 35.91 3 NA 0.00 2.05

Major Drugs NVS Novartis AG (ADR) NYSE Healthcare 110,348.410 1.56 11.18 47.37 3.75 23.71 2,329.500 2,300.000 7.94 24.610 1.27 0 1.86 0.21 1.97

Major Drugs PFE Pfizer Inc. NYSE Healthcare 201,795.230 1.45 9.34 27.14 3.00 22.16 7,435.340 7,374.100 61.89 -54.540 0.82 -7 2.80 0.29 1.46

Major Drugs PBH Prestige Brands Holdings, Inc. NYSE Healthcare 1,051.450 1.50 14.20 21.03 2.73 NA 50.000 28.000 56.31 28.150 44.00 -11 NA 1.28 2.05

Major Drugs RHHBY Roche Holding Ltd. (ADR) OTC Healthcare 109,373.050 1.86 14.29 63.40 5.05 21.08 1,725.130 1,382.400 0.20 0.120 19.87 0 NA 0.32 2.97

Major Drugs SHR Schering AG (ADR) NYSE Healthcare 11,622.260 1.47 11.65 61.17 3.25 18.99 190.000 155.800 3.46 0.260 18.00 0 2.09 0.08 2.57

Major Drugs SGP Schering-Plough Corp. NYSE Healthcare 27,982.300 3.69 19.78 18.97 4.59 NA 1,475.080 1,431.900 75.79 7.820 2.93 -2 1.16 0.37 2.17

Major Drugs WYE Wyeth NYSE Healthcare 59,375.070 2.03 7.57 44.36 5.65 40.88 1,338.480 1,331.400 74.48 11.680 0.53 -5 2.07 0.73 1.74









492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 08Jul05 27 of 45 10/24/2011 3:30 PM

BioTech Industry 31Mar05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs APPA A.P. Pharma, Inc. NASD Healthcare 36.060 NA NA 1.44 2.55 NA 25.040 24.000 41.07 -0.100 4.15 0 NA 0.00 5.42

Biotechnology & Drugs AAII aaiPharma Inc. NASD Healthcare 20.300 NA NA 0.71 12.73 NA 28.590 20.200 29.37 -0.750 29.34 0 NA 203.07 0.59

Biotechnology & Drugs ASTM Aastrom Biosciences, Inc. NASD Healthcare 210.060 NA NA 2.08 8.04 NA 100.990 95.900 6.06 3.740 5.04 2 NA 0.00 34.89

Biotechnology & Drugs ABAX Abaxis, Inc. NASD Healthcare 175.160 NA NA 8.85 2.93 7.96 19.790 19.000 55.48 0.980 4.00 -4 NA 0.00 5.99

Biotechnology & Drugs ABGX Abgenix, Inc. NASD Healthcare 624.360 NA NA 7.00 2.70 NA 89.190 77.500 85.51 10.880 13.11 0 NA 1.65 12.46

Biotechnology & Drugs ABRX Able Laboratories Inc. NASD Healthcare 421.050 0.87 25.00 23.46 4.47 31.36 17.950 16.000 83.21 1.550 4.48 -9 NA 0.03 11.37

Biotechnology & Drugs ACAD ACADIA Pharmaceuticals Inc. NASD Healthcare 116.380 NA NA 6.90 3.12 NA 16.870 10.500 31.99 0.780 37.75 0 NA 0.08 4.80

Biotechnology & Drugs ACAM Acambis plc (ADR) NASD Healthcare 480.120 NA NA 9.09 2.46 13.41 52.820 45.400 3.40 0.880 14.05 0 NA 0.06 2.73

Biotechnology & Drugs ACCL Accelrys, Inc. NASD Healthcare 157.630 NA NA 5.93 1.53 NA 26.580 26.000 64.27 0.220 2.19 0 NA 0.02 1.65

Biotechnology & Drugs AKC Access Pharmaceuticals AMEX Healthcare 38.650 NA NA 2.49 NA NA 15.520 15.000 26.60 -0.840 3.36 0 NA NA 0.58

Biotechnology & Drugs AGNM Acrongenomics Inc. NASD Healthcare 63.020 NA NA 4.18 125.61 NA 15.080 7.500 0.00 0.000 50.26 0 NA 0.00 0.14

Biotechnology & Drugs ACUR Acura Pharmaceuticals, Inc. OTC Healthcare 13.260 NA NA 0.59 NA NA 22.470 19.300 0.63 0.000 14.10 0 NA NA 3.45

Biotechnology & Drugs ACUS Acusphere, Inc. NASD Healthcare 96.460 NA NA 5.41 2.12 NA 17.830 16.200 45.03 0.740 9.14 -21 NA 0.17 3.60

Biotechnology & Drugs ADZA Adeza Biomedical Corporation NASD Healthcare 200.500 1.73 20.00 12.18 2.45 18.59 16.460 3.800 62.91 10.360 77.11 0 NA 0.00 13.66

Biotechnology & Drugs ADH Adherex Technologies Inc. AMEX Healthcare 44.860 NA NA 0.25 NA NA 179.460 151.700 8.50 15.260 15.47 0 NA NA NA

Biotechnology & Drugs ADLR Adolor Corporation NASD Healthcare 387.740 -0.43 15.00 9.92 3.15 NA 39.090 36.700 80.12 5.420 6.11 2 NA 0.00 8.79

Biotechnology & Drugs AVM Advanced Magnetics, Inc. AMEX Healthcare 70.170 NA NA 8.78 4.63 NA 7.990 7.000 37.07 0.160 11.56 1 NA 0.00 3.90

Biotechnology & Drugs APPI Advanced Plant Pharmaceuticals Inc. OTC Healthcare 2.680 NA NA 0.00 NA NA 705.380 355.200 0.00 0.000 49.64 0 NA NA 0.02

Biotechnology & Drugs ATISZ Advanced Tissue Sciences OTC Healthcare 6.220 NA NA 0.09 0.43 NA 73.150 47.600 1.05 -0.340 34.93 0 NA 0.31 1.21

Biotechnology & Drugs ADVR Advanced Viral Research OTC Healthcare 76.610 NA NA 0.11 9.16 NA 696.490 640.800 0.03 0.120 8.00 0 NA 0.00 9.16

Biotechnology & Drugs AVNC Advancis Pharmaceutical Corporation NASD Healthcare 84.510 -0.08 30.00 3.70 2.11 NA 22.840 9.400 18.80 -1.140 58.84 -1 NA 0.07 2.71

Biotechnology & Drugs ANX ADVENTRX Pharmaceuticals, Inc. AMEX Healthcare 90.940 NA NA 1.69 6.21 NA 53.810 44.000 7.98 -0.090 18.05 0 NA 0.00 21.61

Biotechnology & Drugs AOLS Aeolus Pharmaceuticals, Inc. OTC Healthcare 9.780 NA NA 0.70 2.71 NA 13.980 5.600 7.16 0.000 59.93 1 NA 0.22 5.00

Biotechnology & Drugs AEZS AEterna Zentaris Inc. (USA) NASD Healthcare 233.840 NA NA 5.12 2.35 NA 45.670 45.200 3.47 0.260 0.95 0 NA 0.64 2.00

Biotechnology & Drugs AEMD Aethlon Medical, Inc. OTC Healthcare 5.300 NA NA 0.33 NA NA 16.050 11.900 NA NA 25.84 NA NA NA 0.02

Biotechnology & Drugs AFFX Affymetrix, Inc. NASD Healthcare 2,609.600 1.14 33.33 42.81 10.22 58.97 60.960 60.700 95.00 4.890 0.50 -34 NA 0.48 3.34

Biotechnology & Drugs AKN Akorn, Inc. AMEX Healthcare 57.320 NA NA 2.77 10.26 NA 20.690 6.700 25.83 4.760 67.62 -2 NA 0.23 1.87

Biotechnology & Drugs AMRI Albany Molecular Research NASD Healthcare 328.310 1.45 15.00 10.28 1.11 NA 31.940 14.000 63.85 0.900 56.16 13 NA 0.18 9.03

Biotechnology & Drugs ALXN Alexion Pharmaceuticals, Inc. NASD Healthcare 605.150 NA NA 21.67 4.64 NA 27.930 27.000 95.00 0.020 3.34 -17 NA 2.07 2.72

Biotechnology & Drugs ACEL Alfacell Corporation NASD Healthcare 69.430 NA NA 1.97 10.97 NA 35.250 34.600 10.16 2.000 1.83 3 NA 0.03 4.48

Biotechnology & Drugs ALKS Alkermes, Inc. NASD Healthcare 935.420 -0.58 25.00 10.38 49.80 NA 90.120 86.500 90.16 1.580 4.02 -3 NA 8.33 3.90

Biotechnology & Drugs AGN Allergan, Inc. NYSE Healthcare 9,326.680 1.19 18.65 69.47 8.18 24.49 134.250 131.600 88.62 7.830 1.98 0 0.58 0.52 2.99

Biotechnology & Drugs ALLP Alliance Pharmaceutical Corp. OTC Healthcare 5.460 NA NA 0.17 NA 0.60 33.120 30.800 1.11 -2.960 7.01 0 NA NA 0.46

Biotechnology & Drugs ALTH Allos Therapeutics, Inc. NASD Healthcare 64.220 NA NA 2.06 2.69 NA 31.180 30.600 29.23 1.810 1.78 4 NA 0.00 10.91

Biotechnology & Drugs ALNY Alnylam Pharmaceuticals, Inc. NASD Healthcare 147.230 NA NA 7.33 3.12 NA 20.090 11.000 14.95 0.060 45.24 -27 NA 0.14 7.33

Biotechnology & Drugs ALO Alpharma Inc. NYSE Healthcare 649.090 1.77 10.68 12.32 0.58 157.95 52.690 40.200 76.54 1.610 23.70 -2 1.46 0.65 1.80

Biotechnology & Drugs AAA Altana AG(ADR) NYSE Healthcare 8,590.610 NA NA 63.50 3.98 17.01 135.290 67.600 1.02 -0.780 50.03 0 1.56 0.04 NA

Biotechnology & Drugs ALT Alteon Inc. AMEX Healthcare 28.600 NA NA 0.59 2.25 NA 48.470 45.100 19.77 -0.070 6.96 0 NA 0.00 6.64

Biotechnology & Drugs AMAR Amarillo Biosciences, Inc OTC Healthcare 5.290 NA NA 0.40 NA NA 13.240 7.800 0.20 0.010 41.06 0 NA NA 0.01

Biotechnology & Drugs AMRN Amarin Corporation plc (ADR) NASD Healthcare 67.170 NA NA 2.14 2.52 NA 31.390 21.300 0.12 0.020 32.14 0 NA 0.12 2.97

Biotechnology & Drugs MABAA American Biogenetic Sciences, Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 44.950 34.500 0.00 0.000 23.25 0 NA NA 0.06

Biotechnology & Drugs AOBO American Oriental Bioengineering, Inc. OTC Healthcare 47.760 NA NA 1.42 1.92 8.21 33.630 11.200 0.00 0.000 66.70 0 NA 0.06 3.53

Biotechnology & Drugs APPX American Pharmaceutical Partners, Inc. NASD Healthcare 3,649.640 0.95 30.98 51.74 11.69 66.76 70.540 21.000 25.56 -1.590 70.48 1 NA 0.00 4.38

Biotechnology & Drugs ABC AmerisourceBergen Corp. NYSE Healthcare 6,365.210 1.46 12.27 57.29 1.44 15.16 111.110 109.800 92.88 6.960 1.18 -2 0.18 0.29 1.34

Biotechnology & Drugs AMGN Amgen, Inc. NASD Healthcare 72,920.670 1.17 17.81 58.21 3.72 32.43 1,252.720 1,244.200 68.36 45.640 0.68 -17 NA 0.26 2.21

Biotechnology & Drugs AMLN Amylin Pharmaceuticals NASD Healthcare 1,820.340 NA NA 17.49 NA NA 104.080 99.100 73.37 3.600 4.78 -34 NA NA 7.73

Biotechnology & Drugs ANDS Anadys Pharmaceuticals, Inc. NASD Healthcare 164.020 NA NA 7.36 4.33 NA 22.290 17.200 29.16 0.410 22.82 0 NA 0.08 7.35

Biotechnology & Drugs ADRX Andrx Corporation NASD Healthcare 1,655.670 1.04 18.57 22.67 2.37 25.39 73.030 71.300 73.02 4.080 2.37 0 NA 0.00 2.28

Biotechnology & Drugs ANPI Angiotech Pharmaceuticals, Inc. (USA) NASD Healthcare 1,288.750 0.76 20.25 15.35 2.92 25.97 83.960 78.900 57.72 3.040 6.02 0 NA 0.00 12.01

Biotechnology & Drugs ANIK Anika Therapeutics, Inc. NASD Healthcare 130.510 NA NA 12.80 4.31 12.93 10.200 8.600 41.83 0.410 15.65 -9 NA 0.00 8.71

Biotechnology & Drugs ANXB Antex Biologics, Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 12.410 10.300 NA NA 16.99 NA NA NA 0.79

Biotechnology & Drugs AGEN Antigenics, Inc. NASD Healthcare 305.000 NA NA 6.70 2.47 NA 45.520 22.200 24.74 -3.920 51.23 5 NA 0.09 5.62

Biotechnology & Drugs APHT Aphton Corporation NASD Healthcare 48.130 -0.04 40.00 1.27 1.64 NA 37.900 36.500 40.15 0.030 3.69 2 NA 0.40 7.06

Biotechnology & Drugs ARNA Arena Pharmaceuticals NASD Healthcare 177.790 NA NA 5.05 0.94 NA 35.210 32.700 46.86 1.250 7.12 0 NA 0.00 7.94

Biotechnology & Drugs AGNT Argonaut Technologies NASD Healthcare 18.410 NA NA 0.89 0.49 NA 20.690 20.200 40.09 0.700 2.35 -12 NA 0.00 4.93

Biotechnology & Drugs ARIA Ariad Pharmaceuticals, Inc. NASD Healthcare 295.820 NA NA 5.60 4.38 NA 52.820 51.100 42.10 -0.550 3.27 0 NA 0.14 9.01

Biotechnology & Drugs ARQL ArQule, Inc. NASD Healthcare 162.660 NA NA 4.69 1.63 NA 34.680 33.900 32.86 0.270 2.26 1 NA 0.00 3.77

Biotechnology & Drugs ARRY Array BioPharma Inc. NASD Healthcare 268.340 -0.20 50.00 7.01 2.38 NA 38.280 33.000 73.36 8.320 13.79 1 NA 0.00 4.85

Biotechnology & Drugs ASPV Aspreva Pharmaceuticals Corporation NASD Healthcare 479.400 NA NA 14.55 NA NA 32.950 0.000 0.00 0.000 78.15 7 NA NA NA

Biotechnology & Drugs ASTR Astralis, Ltd. OTC Healthcare 22.560 NA NA 0.31 3.52 NA 73.170 20.500 0.82 -0.260 71.98 7 NA 0.00 10.23

Biotechnology & Drugs AGIX AtheroGenics, Inc. NASD Healthcare 493.080 NA NA 13.09 NA NA 37.670 36.400 95.00 2.550 3.37 -3 NA NA 6.74

Biotechnology & Drugs AIMM AutoImmune Inc. OTC Healthcare 16.920 NA NA 1.00 1.67 NA 16.920 16.800 30.26 0.000 0.71 0 NA 0.00 101.23

Biotechnology & Drugs AUXL Auxilium Pharmaceuticals, Inc. NASD Healthcare 123.230 -0.13 30.00 5.98 2.88 NA 20.610 8.900 83.82 2.350 56.81 0 NA 0.01 4.45

Biotechnology & Drugs AVN AVANIR Pharmaceuticals AMEX Healthcare 214.990 NA NA 2.20 21.06 NA 97.720 89.000 30.48 3.170 8.93 -2 NA 0.11 3.07

Biotechnology & Drugs AVAN AVANT Immunotherapeutics, Inc. NASD Healthcare 120.830 NA NA 1.63 3.15 NA 74.130 72.600 21.20 1.670 1.93 0 NA 0.01 6.34







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BioTech Industry 31Mar05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs AVXT AVAX Technologies, Inc. OTC Healthcare 12.990 NA NA 0.36 6.55 NA 36.070 34.500 6.29 2.250 4.36 0 NA 0.17 1.17

Biotechnology & Drugs AVII AVI BioPharma, Inc. NASD Healthcare 110.360 NA NA 2.50 3.44 NA 44.140 34.400 10.13 0.660 22.07 0 NA 0.00 8.98

Biotechnology & Drugs AVGN Avigen, Inc. NASD Healthcare 56.860 NA NA 2.79 0.71 NA 20.380 20.300 42.28 0.990 0.40 0 NA 0.00 41.74

Biotechnology & Drugs AXCA Axcan Pharma Inc. (USA) NASD Healthcare 766.220 1.35 15.00 16.81 1.86 18.53 45.580 41.900 45.38 0.280 8.08 0 NA 0.32 3.05

Biotechnology & Drugs AXJ AXM Pharma, Inc. AMEX Healthcare 44.020 NA NA 2.74 5.10 NA 16.070 9.800 2.89 0.320 39.01 0 NA 0.00 3.96

Biotechnology & Drugs AXYX Axonyx Inc. NASD Healthcare 66.010 NA NA 1.23 0.70 NA 53.670 51.300 53.52 0.970 16.67 -9 NA 0.01 14.47

Biotechnology & Drugs BRL Barr Pharmaceuticals, Inc. NYSE Healthcare 5,011.300 1.30 15.78 48.83 4.64 32.21 102.630 97.500 76.03 6.570 5.00 -11 NA 0.03 3.91

Biotechnology & Drugs BTRX Barrier Therapeutics, Inc. NASD Healthcare 338.430 NA NA 15.49 3.51 NA 21.850 16.800 60.47 -0.010 23.11 -9 NA 0.01 14.34

Biotechnology & Drugs BGCC Beluga Composites Corp. OTC Healthcare 0.010 NA NA 0.25 NA NA 0.030 0.010 NA NA 77.14 NA NA 0.02 2.46

Biotechnology & Drugs BNT Bentley Pharmaceuticals, Inc. NYSE Healthcare 156.900 0.77 32.00 7.36 1.75 29.21 21.320 19.700 38.97 -0.120 7.59 2 NA 0.04 2.71

Biotechnology & Drugs BASI Bioanalytical Systems, Inc. NASD Healthcare 48.940 NA NA 10.05 2.44 167.50 4.870 3.200 7.08 0.020 34.29 0 NA 0.96 0.99

Biotechnology & Drugs BCRX BioCryst Pharmaceuticals, Inc. NASD Healthcare 120.540 NA NA 4.61 3.42 NA 26.150 19.400 31.63 0.260 25.80 0 NA 0.00 8.43

Biotechnology & Drugs BDSI BioDelivery Sciences Int'l, Inc. NASD Healthcare 21.940 NA NA 3.07 10.54 NA 7.150 1.700 0.95 0.050 76.21 32 NA 0.11 1.59

Biotechnology & Drugs BIVN Bioenvision Inc. NASD Healthcare 164.430 NA NA 5.75 7.37 NA 28.600 28.500 32.53 1.310 0.08 -19 NA 0.00 6.47

Biotechnology & Drugs BIIB Biogen Idec Inc NASD Healthcare 11,510.890 1.19 18.10 34.51 1.69 297.50 333.550 331.100 83.45 2.400 0.74 -47 NA 0.00 2.85

Biotechnology & Drugs BMRN BioMarin Pharmaceutical NASD Healthcare 332.230 NA NA 5.15 NA NA 64.510 63.500 71.90 -0.260 1.57 0 NA NA 1.22

Biotechnology & Drugs BIOM Biomira Inc. (USA) NASD Healthcare 145.710 NA NA 1.86 4.76 NA 78.340 73.600 5.49 1.290 6.05 0 NA 0.02 15.34

Biotechnology & Drugs BNTK Bionet Technologies, Inc. OTC Healthcare 0.010 NA NA 0.00 0.14 NA 13.810 8.700 NA NA 37.02 NA NA 0.00 0.90

Biotechnology & Drugs BNRX Bionutrics, Inc. OTC Healthcare 7.400 NA NA 1.70 NA NA 4.350 2.100 NA NA 71.34 NA NA NA 0.19

Biotechnology & Drugs BPRG BioProgress PLC (USA) NASD Healthcare 124.460 NA NA 11.00 2.48 NA 11.310 10.750 0.05 0.010 4.99 0 NA 0.00 2.83

Biotechnology & Drugs BIOP BioPulse International OTC Healthcare 0.060 NA NA 0.00 NA NA 15.450 7.600 NA NA 50.81 NA NA NA 0.04

Biotechnology & Drugs BPUR Biopure Corporation NASD Healthcare 48.550 NA NA 0.33 0.84 NA 145.930 140.900 2.28 -2.430 3.45 0 NA 0.00 7.29

Biotechnology & Drugs BPA BioSante Pharmaceuticals, Inc. AMEX Healthcare 73.830 NA NA 4.00 3.77 NA 18.460 11.600 26.96 2.610 21.23 6 NA 0.00 15.58

Biotechnology & Drugs BSTE Biosite Incorporated NASD Healthcare 873.620 1.13 18.00 52.03 3.88 21.51 16.790 15.300 95.00 -0.490 8.88 -40 NA 0.10 3.49

Biotechnology & Drugs BSLU Bio-Solutions International, Inc. OTC Healthcare 0.240 NA NA 1.20 NA NA 0.200 0.100 NA NA 46.94 NA NA NA NA

Biotechnology & Drugs BIOI BioSource International, Inc. NASD Healthcare 69.470 3.30 10.00 7.27 1.87 191.32 9.560 7.800 34.41 0.070 18.38 1 NA 0.00 3.14

Biotechnology & Drugs BSTC BioSpecifics Technologies Corp. OTC Healthcare 5.330 NA NA 1.00 2.76 NA 5.330 3.000 2.70 0.000 43.67 2 NA 1.03 0.65

Biotechnology & Drugs BIOHF Biotech Holdings Ltd. (USA) OTC Healthcare 33.310 NA NA 0.37 NA NA 90.030 44.100 NA NA 51.02 NA NA NA 0.31

Biotechnology & Drugs BTX BioTime, Inc. AMEX Healthcare 20.130 NA NA 1.13 22.84 NA 17.810 17.100 1.65 0.030 3.99 0 NA 0.00 12.23

Biotechnology & Drugs BTRNQ BioTransplant Inc. OTC Healthcare 0.060 NA NA 0.00 0.01 NA 25.390 19.600 0.03 -0.110 22.79 0 NA 0.04 2.39

Biotechnology & Drugs BVF Biovail Corporation (USA) NYSE Healthcare 2,399.160 0.61 16.49 15.08 2.28 14.90 159.100 133.600 37.07 5.090 16.03 0 NA 0.42 1.65

Biotechnology & Drugs BCII Bone Care International, Inc. NASD Healthcare 517.690 1.00 65.00 25.94 4.03 125.31 19.960 14.500 80.75 3.280 27.34 -6 NA 0.00 12.39

Biotechnology & Drugs BLSID Boston Life Sciences, Inc. NASD Healthcare 22.230 NA NA 2.50 NA NA 8.890 8.600 NA NA 3.30 NA NA 1.59 1.28

Biotechnology & Drugs BDY Bradley Pharmaceuticals, Inc. NYSE Healthcare 151.400 0.36 20.67 9.56 0.94 7.84 15.840 13.200 78.32 -1.570 12.23 0 NA 0.67 3.27

Biotechnology & Drugs CADKF Cade Struktur Corporation OTC Healthcare 0.000 NA NA 0.00 2.06 3.45 8.340 7.700 NA NA 7.63 NA NA 0.00 1.50

Biotechnology & Drugs KDUS Cadus Corporation OTC Healthcare 19.850 NA NA 1.51 0.78 NA 13.140 7.600 1.93 0.040 42.18 0 NA 0.00 1,360.22

Biotechnology & Drugs KAL Callisto Pharmaceuticals, Inc. AMEX Healthcare 43.760 NA NA 1.50 7.82 NA 29.180 19.000 4.75 1.190 34.88 5 NA 0.00 6.96

Biotechnology & Drugs CBM Cambrex Corporation NYSE Healthcare 556.100 2.01 11.67 21.30 1.52 NA 26.110 25.200 91.82 2.120 3.48 -13 0.56 0.61 2.80

Biotechnology & Drugs CATG NASD

Cambridge Antibody Tech. Group plc (ADR) Healthcare 514.700 NA NA 12.52 2.32 NA 41.110 28.000 3.53 0.540 27.70 0 NA 0.00 10.88

Biotechnology & Drugs CNVX CancerVax Corporation NASD Healthcare 183.270 NA NA 6.59 2.57 NA 27.810 17.200 24.85 0.080 38.15 0 NA 0.10 4.77

Biotechnology & Drugs CPD A

Caraco Pharmaceutical Laboratories Ltd. MEX Healthcare 215.630 NA 33.00 8.18 NA NA 26.360 9.500 9.58 -0.020 63.96 -3 NA 0.00 2.14

Biotechnology & Drugs CAH Cardinal Health, Inc. NYSE Healthcare 24,109.850 1.27 13.55 55.80 2.82 19.44 432.080 427.000 82.70 34.610 1.18 -9 0.22 0.33 1.37

Biotechnology & Drugs CRME Cardiome Pharma Corp.(USA) NASD Healthcare 254.270 NA NA 6.20 6.68 NA 41.010 37.700 24.12 3.300 8.07 0 NA 0.02 3.07

Biotechnology & Drugs CVBT Cardiovascular Biotherapeutics, Inc. OTC Healthcare 1,258.120 NA NA 11.00 NA NA 114.370 1.800 NA NA 98.43 NA NA NA 1.47

Biotechnology & Drugs CARN Carrington Laboratories, Inc. NASD Healthcare 55.040 NA NA 5.16 4.21 2,580.00 10.670 10.600 13.59 0.300 0.63 -1 NA 0.32 1.31

Biotechnology & Drugs CRA Celera Genomics, Applera Corp NYSE Healthcare 751.930 NA NA 10.25 0.86 NA 73.360 72.300 77.88 3.100 1.44 -1 NA 0.00 15.53

Biotechnology & Drugs CELG Celgene Corporation NASD Healthcare 5,605.640 1.78 33.25 34.05 11.77 111.64 164.630 148.200 81.57 2.130 10.03 -9 NA 0.84 6.01

Biotechnology & Drugs CEGE Cell Genesys, Inc. NASD Healthcare 205.480 NA NA 4.53 1.28 NA 45.360 45.000 70.57 8.260 0.80 0 NA 1.24 5.10

Biotechnology & Drugs CTIC Cell Therapeutics, Inc. NASD Healthcare 219.130 -0.07 25.00 3.59 NA NA 61.040 58.400 60.05 6.890 4.56 -9 NA NA 3.75

Biotechnology & Drugs CLGY Cellegy Pharmaceuticals, Inc. NASD Healthcare 42.140 NA NA 1.62 NA NA 26.010 18.900 11.20 -0.080 27.35 -11 NA NA 4.75

Biotechnology & Drugs CVM CEL-SCI Corporation AMEX Healthcare 46.970 NA NA 0.65 11.32 NA 72.270 67.100 1.30 -4.640 7.16 -13 NA 0.00 11.45

Biotechnology & Drugs CEPH Cephalon, Inc. NASD Healthcare 2,717.580 0.67 24.17 46.83 3.19 NA 58.030 58.000 NA NA 0.05 -10 NA 1.55 5.46

Biotechnology & Drugs CERS Cerus Corporation NASD Healthcare 68.190 NA NA 3.07 3.17 NA 22.210 21.200 35.68 0.080 4.48 2 NA 1.82 1.31

Biotechnology & Drugs CHTL Chantal Pharmaceutical OTC Healthcare 0.040 NA NA 0.00 0.03 NA 40.810 31.400 NA NA 23.06 NA NA 0.62 0.26

Biotechnology & Drugs CHTT Chattem Inc. NASD Healthcare 882.080 1.92 11.58 44.47 8.25 523.18 19.840 18.400 70.24 1.680 7.24 -5 NA 1.87 2.88

Biotechnology & Drugs CHIR Chiron Corporation NASD Healthcare 6,558.670 1.42 16.28 35.06 2.52 125.21 187.070 108.500 41.71 0.150 42.00 0 NA 0.42 3.26

Biotechnology & Drugs CNXS CNS, Inc. NASD Healthcare 251.960 1.77 13.33 17.80 3.75 26.37 14.160 11.500 53.91 1.170 18.76 -10 1.12 0.00 4.50

Biotechnology & Drugs CLSCE Cobalis Corporation OTC Healthcare 13.080 NA NA 0.57 NA NA 22.940 8.300 0.00 0.000 64.12 -3 NA NA 0.00

Biotechnology & Drugs CGPI CollaGenex Pharmaceutical, Inc NASD Healthcare 67.300 NA NA 4.67 1.63 14.02 14.410 12.300 61.45 0.240 14.65 0 NA 0.00 4.71

Biotechnology & Drugs CBRX Columbia Laboratories NASD Healthcare 79.750 NA NA 1.91 NA NA 41.750 41.700 41.65 -0.620 0.13 0 NA NA 1.50

Biotechnology & Drugs CBTE Commonwealth Biotechnologies, Inc. NASD Healthcare 12.330 NA NA 3.85 1.89 55.00 3.200 2.200 8.81 0.110 31.29 1 NA 0.56 11.40

Biotechnology & Drugs COGE Compare Generiks, Inc. OTC Healthcare 0.000 NA NA 0.00 0.00 0.00 4.910 3.800 NA NA 22.69 NA NA 0.00 1.34

Biotechnology & Drugs CGEN Compugen Ltd. (USA) NASD Healthcare 107.660 NA NA 4.01 2.24 NA 26.850 23.600 25.44 -1.350 12.10 0 NA 0.00 6.54

Biotechnology & Drugs CNCT Connetics Corporation NASD Healthcare 908.580 0.88 33.67 25.29 7.08 50.48 35.930 35.500 95.00 3.370 1.19 -30 NA 0.70 3.60

Biotechnology & Drugs VEGF Corautus Genetics Inc. NASD Healthcare 67.250 NA NA 4.61 4.50 NA 14.590 8.900 19.43 -0.400 38.99 0 NA 0.69 19.20





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Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs CORT Corcept Therapeutics Incorporated NASD Healthcare 103.030 -0.14 30.00 4.54 2.23 NA 22.690 8.600 25.26 1.100 62.11 -28 NA 0.00 20.95

Biotechnology & Drugs CONX Corgenix Medical Corporation OTC Healthcare 1.680 NA NA 0.27 2.29 NA 6.220 4.700 0.00 0.000 24.49 3 NA 1.28 1.29

Biotechnology & Drugs CGTK Corgentech, Inc. NASD Healthcare 64.480 NA NA 2.32 0.61 NA 27.790 16.100 50.08 -0.880 42.07 -4 NA 0.00 7.06

Biotechnology & Drugs CRXA Corixa Corporation NASD Healthcare 182.240 NA NA 3.07 9.00 NA 59.360 51.400 52.18 2.080 13.48 0 NA 6.30 2.78

Biotechnology & Drugs COR Cortex Pharmaceuticals AMEX Healthcare 63.460 NA NA 2.23 3.34 NA 28.460 28.400 7.07 0.640 0.19 3 NA 0.00 12.53

Biotechnology & Drugs CTRX Cotherix, Inc NASD Healthcare 130.030 -0.12 30.00 6.62 2.98 NA 19.640 5.000 13.91 2.730 74.54 8 NA 0.00 10.49

Biotechnology & Drugs CVGR Covalent Group, Inc. NASD Healthcare 30.650 NA NA 2.30 3.36 NA 13.320 12.300 24.33 0.450 7.69 0 NA 0.01 2.73

Biotechnology & Drugs CVD Covance Inc. NYSE Healthcare 2,989.290 1.34 18.88 47.61 4.65 31.38 62.790 60.900 82.87 2.870 0.78 -23 NA 0.00 2.32

Biotechnology & Drugs CRTX Critical Therapeutics, Inc. NASD Healthcare 163.620 NA NA 6.79 2.50 NA 24.100 11.800 18.52 0.160 51.03 0 NA 0.03 4.94

Biotechnology & Drugs CRXL Crucell N.V. (ADR) NASD Healthcare 481.200 NA NA 13.05 4.72 NA 36.870 33.200 13.98 0.540 9.96 0 NA 0.02 5.70

Biotechnology & Drugs CBST Cubist Pharmaceuticals NASD Healthcare 545.020 -1.01 15.00 10.62 26.06 NA 51.320 50.500 87.49 10.440 1.60 -1 NA 7.93 4.20

Biotechnology & Drugs CRGN CuraGen Corporation NASD Healthcare 210.960 NA NA 4.16 1.97 NA 50.710 40.800 60.96 0.680 19.55 1 NA 2.25 17.67

Biotechnology & Drugs CRIS Curis, Inc. NASD Healthcare 169.300 NA NA 3.58 3.48 NA 47.290 45.600 34.53 4.280 3.51 -3 NA 0.14 8.89

Biotechnology & Drugs CVTX CV Therapeutics, Inc. NASD Healthcare 733.390 NA NA 20.36 8.88 NA 36.020 35.600 91.01 4.600 0.89 0 NA 4.15 9.22

Biotechnology & Drugs CYAN Cyanotech Corporation NASD Healthcare 25.470 NA NA 1.22 1.68 25.40 20.890 16.800 11.36 -0.040 19.59 0 NA 0.15 4.08

Biotechnology & Drugs CYPB Cypress Bioscience, Inc. NASD Healthcare 273.430 NA NA 9.14 2.95 NA 29.920 26.600 75.18 1.360 10.87 -9 NA 0.00 21.80

Biotechnology & Drugs CYTO Cytogen Corporation NASD Healthcare 89.380 NA NA 5.79 1.95 NA 15.440 15.400 51.92 -0.320 0.24 1 NA 0.05 5.74

Biotechnology & Drugs CYTK Cytokinetics, Inc. NASD Healthcare 186.950 NA NA 6.56 1.74 NA 28.500 11.700 28.80 -2.620 58.94 -7 NA 0.10 9.88

Biotechnology & Drugs CYME Cytomedix, Inc. OTC Healthcare 60.940 NA NA 3.12 8.88 NA 19.530 14.800 1.45 0.000 24.23 -4 NA 0.00 3.80

Biotechnology & Drugs CYTR CytRx Corporation NASD Healthcare 77.810 NA NA 1.37 17.18 NA 56.800 45.400 4.29 0.700 20.07 0 NA 0.00 2.28

Biotechnology & Drugs DKHR D&K Healthcare Resources Inc NASD Healthcare 118.010 3.45 12.25 8.37 0.67 20.62 14.100 13.200 74.85 -0.620 6.38 1 0.72 2.51 2.57

Biotechnology & Drugs DATA DATATRAK International, Inc. NASD Healthcare 113.740 NA NA 16.80 10.99 143.59 6.770 5.500 34.06 0.560 18.76 -10 NA 0.00 5.70

Biotechnology & Drugs DCGN deCODE genetics, Inc. NASD Healthcare 310.720 NA NA 5.70 5.93 NA 54.510 46.200 41.29 0.870 15.11 -10 NA 3.91 5.36

Biotechnology & Drugs DGENQ Deltagen, Inc. OTC Healthcare 6.410 NA NA 0.17 0.47 NA 38.850 14.000 15.91 0.000 63.97 0 NA 0.37 0.23

Biotechnology & Drugs DNDN Dendreon Corporation NASD Healthcare 322.610 NA NA 5.45 1.62 NA 59.190 28.900 57.77 0.120 51.18 7 NA 0.02 11.86

Biotechnology & Drugs DEPO DepoMed, Inc. NASD Healthcare 156.340 -0.33 30.00 3.94 NA NA 39.680 35.400 59.99 1.200 42.54 0 NA 1.24 5.34

Biotechnology & Drugs DSCI Derma Sciences, Inc. OTC Healthcare 4.950 NA NA 0.52 0.70 NA 9.520 8.600 0.27 0.000 9.70 1 NA 0.73 1.43

Biotechnology & Drugs DIGE Digene Corporation NASD Healthcare 414.830 2.73 30.00 20.75 5.03 32.02 19.990 15.200 83.06 2.150 23.97 -5 NA 0.01 4.94

Biotechnology & Drugs DSCO Discovery Laboratories NASD Healthcare 301.270 NA NA 5.63 12.93 NA 53.510 49.100 43.58 1.020 8.25 4 NA 0.40 3.78

Biotechnology & Drugs DPII Discovery Partners Int'l NASD Healthcare 82.810 NA NA 3.20 0.76 21.33 25.880 24.100 78.53 -0.090 6.60 0 NA 0.00 14.12

Biotechnology & Drugs DVSA Diversa Corporation NASD Healthcare 217.540 -0.14 50.00 4.98 1.44 NA 43.680 26.200 46.73 0.490 40.18 2 NA 0.12 4.42

Biotechnology & Drugs DOCP DocPlanet.com Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 7.600 4.100 0.03 0.000 46.02 0 NA NA 0.38

Biotechnology & Drugs DOR DOR BioPharma, Inc. AMEX Healthcare 19.670 NA NA 0.39 3.70 NA 50.440 47.600 3.20 0.280 5.63 0 NA 0.03 4.04

Biotechnology & Drugs DOVP DOV Pharmaceutical, Inc. NASD Healthcare 310.100 NA NA 13.68 10.51 NA 21.440 11.800 79.84 1.390 45.30 -1 NA 2.47 5.70

Biotechnology & Drugs RDY Dr Reddy's Laboratories Limited (ADR) NYSE Healthcare 1,311.530 NA NA 17.14 2.75 66.18 76.520 56.600 15.18 4.760 26.03 0 0.63 0.10 2.70

Biotechnology & Drugs DRUG Dragon Pharmaceuticals Inc. (USA) OTC Healthcare 16.480 NA NA 0.80 1.85 NA 20.600 16.900 0.00 0.000 17.97 0 NA 0.00 4.24

Biotechnology & Drugs DRAX DRAXIS Health Inc. (USA) NASD Healthcare 211.230 NA NA 5.15 3.02 26.55 41.020 33.600 43.16 1.860 18.08 0 NA 0.00 2.33

Biotechnology & Drugs DRRX DURECT Corporation NASD Healthcare 188.830 NA NA 3.64 10.27 NA 51.880 29.000 55.13 -0.070 44.10 0 NA 3.38 8.67

Biotechnology & Drugs DUSA DUSA Pharmaceuticals, Inc NASD Healthcare 147.680 -2.08 30.00 8.73 2.81 NA 16.920 16.600 58.81 0.890 1.87 -3 NA 0.00 13.34

Biotechnology & Drugs DYAD Dyadic International, Inc. OTC Healthcare 41.660 NA NA 2.99 17.23 NA 13.930 9.500 4.31 0.600 31.82 0 NA 2.62 2.11

Biotechnology & Drugs DYAX Dyax Corp. NASD Healthcare 101.520 NA NA 3.22 2.12 NA 31.530 27.600 61.34 1.010 12.60 0 NA 0.26 3.80

Biotechnology & Drugs DVAX Dynavax Technologies Corp NASD Healthcare 115.560 NA NA 4.67 1.79 NA 24.750 19.300 31.65 1.050 22.02 -9 NA 0.00 8.80

Biotechnology & Drugs EPEI EAPI Entertainment, Inc. OTC Healthcare 9.760 NA NA 0.69 NA NA 14.140 12.000 NA NA 14.96 NA NA NA 0.00

Biotechnology & Drugs EW Edwards Lifesciences Corp NYSE Healthcare 2,575.180 1.71 13.42 43.22 4.09 NA 59.580 59.500 94.54 2.410 0.14 -6 NA 0.43 1.88

Biotechnology & Drugs ESALY Eisai Co., Ltd (ADR) OTC Healthcare 9,755.270 NA NA 33.90 2.27 18.10 287.770 218.700 0.32 0.140 24.00 0 NA 0.00 2.68

Biotechnology & Drugs ELN Elan Corporation, plc (ADR) NYSE Healthcare 1,259.450 -0.18 18.46 3.24 6.10 NA 388.720 380.900 56.34 10.030 2.01 0 NA 11.22 4.41

Biotechnology & Drugs ELI Elite Pharmaceuticals, Inc. AMEX Healthcare 68.860 NA NA 4.40 9.11 NA 15.650 15.600 3.80 0.550 0.31 -6 NA 0.43 5.32

Biotechnology & Drugs EMBX Embrex, Inc. NASD Healthcare 93.060 NA NA 11.72 1.98 31.85 7.940 6.900 42.80 0.270 13.11 -5 NA 0.19 2.77

Biotechnology & Drugs EMIS Emisphere Technologies NASD Healthcare 70.460 NA NA 3.67 NA NA 19.200 16.300 30.82 0.400 15.10 0 NA NA 2.76

Biotechnology & Drugs ENCY Encysive Pharmaceuticals, Inc. NASD Healthcare 592.460 NA NA 10.22 9.62 NA 57.970 56.800 71.43 3.220 2.02 -3 NA 0.03 4.77

Biotechnology & Drugs ENDP Endo Pharmaceuticals NASD Healthcare 2,973.740 1.22 15.00 22.55 4.53 20.88 131.870 47.500 54.67 6.990 63.98 -15 NA 0.00 2.08

Biotechnology & Drugs EVSC Endovasc, Inc. OTC Healthcare 4.950 NA NA 0.05 NA NA 105.370 98.600 0.01 0.000 6.42 -1 NA NA 0.17

Biotechnology & Drugs ENMD EntreMed, Inc. NASD Healthcare 89.910 NA NA 2.10 4.12 NA 42.820 20.100 21.15 1.870 52.39 2 NA 0.00 11.72

Biotechnology & Drugs ETOP Entropin, Inc. OTC Healthcare 4.290 NA NA 0.14 NA NA 30.650 26.000 NA NA 11.89 NA NA 0.00 21.58

Biotechnology & Drugs ENZN Enzon Pharmaceuticals, Inc. NASD Healthcare 447.100 2.08 34.33 10.19 1.55 NA 43.880 43.800 78.66 3.940 0.17 0 NA 1.38 6.07

Biotechnology & Drugs ELAB Eon Labs, Inc. NASD Healthcare 2,686.830 1.03 20.83 30.24 6.06 22.98 88.850 28.400 29.50 1.220 68.04 0 NA 0.00 4.50

Biotechnology & Drugs EPMN Epimmune Inc. NASD Healthcare 18.560 NA NA 1.16 1.47 NA 16.000 10.100 14.17 0.640 36.89 0 NA 0.00 4.55

Biotechnology & Drugs EPIX EPIX Pharmaceuticals, Inc. NASD Healthcare 162.400 NA NA 7.00 3.92 NA 23.200 22.800 80.27 -1.330 1.84 -39 NA 2.78 5.76

Biotechnology & Drugs ERGO Ergo Science Corporation OTC Healthcare 12.910 NA NA 2.22 0.59 2.68 5.810 5.500 1.93 0.000 5.40 0 NA 0.00 126.75

Biotechnology & Drugs EXAS EXACT Sciences Corporation NASD Healthcare 93.510 NA NA 3.57 2.46 NA 26.190 19.500 50.42 -4.020 20.32 0 NA 0.12 7.60

Biotechnology & Drugs EXEG eXegenics Inc. OTC Healthcare 7.300 NA NA 0.45 0.81 NA 16.230 15.800 4.66 -0.380 2.64 0 NA 0.00 35.57

Biotechnology & Drugs EXEL Exelixis, Inc. NASD Healthcare 516.300 NA NA 6.78 10.04 NA 76.150 53.800 79.63 3.490 29.35 -25 NA 2.91 2.57

Biotechnology & Drugs EYET Eyetech Pharmaceuticals, Inc. NASD Healthcare 1,182.200 -1.15 43.00 27.50 8.79 NA 42.990 28.300 73.93 3.440 34.17 -23 NA 0.02 7.54

Biotechnology & Drugs FVRL Favrille, Inc. NASD Healthcare 101.680 NA NA 5.08 NA NA 20.020 6.000 0.00 0.000 70.02 7 NA 0.23 5.35

Biotechnology & Drugs FHRX First Horizon Pharmaceutical Corp. NASD Healthcare 597.380 0.65 27.50 16.88 1.92 23.41 35.390 26.100 95.00 5.530 26.29 -3 NA 0.49 7.22





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BioTech Industry 31Mar05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs FLML Flamel Technologies S.A. (ADR) NASD Healthcare 280.170 -2.23 50.00 12.94 2.86 43.86 21.650 21.200 41.35 1.170 2.09 0 NA 0.03 4.68

Biotechnology & Drugs FMTI Forbes Medi-Tech Inc. (USA) NASD Healthcare 71.110 NA NA 2.10 2.48 NA 33.860 32.500 9.18 -0.370 4.03 0 NA 0.07 5.09

Biotechnology & Drugs FRX Forest Laboratories, Inc. NYSE Healthcare 12,983.560 0.80 17.62 36.95 3.85 14.92 351.380 345.000 91.91 10.720 1.82 -13 NA 0.00 5.49

Biotechnology & Drugs GGEN GalaGen Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 12.280 7.500 0.08 0.000 38.90 0 NA NA 0.37

Biotechnology & Drugs GCAN GammaCan International, Inc. OTC Healthcare 39.350 NA NA 1.50 26.88 NA 26.230 21.200 NA NA 19.18 NA NA 0.00 10.93

Biotechnology & Drugs GENR Genaera Corporation NASD Healthcare 130.330 -0.49 15.00 2.28 4.47 NA 57.160 51.200 25.57 2.870 10.43 0 NA 0.00 8.43

Biotechnology & Drugs GNSC Genaissance Pharm. Inc. NASD Healthcare 38.880 NA NA 1.25 2.27 NA 31.130 20.300 27.09 0.260 35.21 0 NA 0.26 1.43

Biotechnology & Drugs GLGC Gene Logic Inc. NASD Healthcare 99.660 NA NA 3.14 0.58 NA 31.740 31.200 49.77 1.130 1.70 0 NA 0.01 4.95

Biotechnology & Drugs GNLB Genelabs Technologies NASD Healthcare 52.990 NA NA 0.60 4.10 NA 88.320 70.400 19.13 -21.210 20.34 0 NA 0.06 3.28

Biotechnology & Drugs GMXX GeneMax Corporation OTC Healthcare 9.120 NA NA 0.31 NA NA 29.400 21.800 0.00 -0.010 25.86 0 NA NA 0.02

Biotechnology & Drugs GCOR Genencor International Inc. NASD Healthcare 1,147.290 NA NA 19.23 3.02 62.44 59.660 8.800 12.81 0.830 87.36 0 NA 0.12 3.27

Biotechnology & Drugs DNA Genentech, Inc. NYSE Healthcare 59,231.040 1.87 27.58 56.61 8.74 77.87 1,046.300 451.200 39.99 6.950 56.88 -25 NA 0.06 2.75

Biotechnology & Drugs GNBT Generex Biotechnology NASD Healthcare 19.300 NA NA 0.54 NA NA 35.730 31.100 2.54 0.680 12.97 0 NA 0.25 0.45

Biotechnology & Drugs GBI Genesis Bioventures, Inc. AMEX Healthcare 4.350 NA NA 0.14 1.04 NA 31.060 16.500 0.17 0.000 46.88 0 NA 0.54 0.02

Biotechnology & Drugs GTOP Genitope Corporation NASD Healthcare 352.400 -0.61 15.00 12.50 3.03 NA 28.190 23.700 32.30 2.840 15.93 -31 NA 0.00 32.48

Biotechnology & Drugs GNTA Genta Incorporated NASD Healthcare 107.750 NA NA 1.13 61.50 NA 95.360 84.800 24.54 -4.660 11.07 1 NA 4.64 0.91

Biotechnology & Drugs GNVC GenVec, Inc. NASD Healthcare 96.250 NA NA 1.73 3.16 NA 55.640 36.700 19.56 -3.900 34.04 1 NA 0.15 4.10

Biotechnology & Drugs GENZ Genzyme Corporation NASD Healthcare 14,385.200 1.43 18.73 57.24 3.25 154.29 251.310 223.900 86.65 6.890 10.91 -14 NA 0.22 2.62

Biotechnology & Drugs GORX GeoPharma, Inc. NASD Healthcare 26.440 NA NA 3.05 1.68 NA 8.670 3.600 12.88 -0.570 58.48 -5 NA 0.24 3.42

Biotechnology & Drugs GERN Geron Corporation NASD Healthcare 278.820 NA NA 6.11 2.61 NA 45.630 43.500 23.26 2.320 5.26 -6 NA 0.03 14.75

Biotechnology & Drugs GILD Gilead Sciences, Inc. NASD Healthcare 16,105.770 1.57 18.25 35.80 8.59 36.38 449.880 445.800 85.18 16.650 0.91 -19 NA 0.00 7.30

Biotechnology & Drugs GLIAQ Gliatech Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 9.680 7.800 0.05 -0.050 19.45 0 NA NA 0.90

Biotechnology & Drugs GLBM Global Marine, Ltd. OTC Healthcare 0.010 NA NA 0.04 0.00 NA 0.380 0.350 NA NA 6.88 NA NA 0.13 4.45

Biotechnology & Drugs GLGS GlycoGenesys, Inc. NASD Healthcare 7.760 NA NA 0.77 2.23 NA 10.080 7.100 5.52 0.120 29.59 0 NA 0.00 2.55

Biotechnology & Drugs GPCB GPC Biotech AG (ADR) NASD Healthcare 330.170 NA NA 11.53 2.04 NA 28.640 25.800 0.89 -0.020 9.89 0 NA 0.01 10.92

Biotechnology & Drugs GTCB GTC Biotherapeutics, Inc. NASD Healthcare 48.990 NA NA 1.05 1.21 NA 46.660 39.700 13.40 -0.580 14.92 2 NA 0.42 1.74

Biotechnology & Drugs GTXI GTx, Inc. NASD Healthcare 224.390 NA NA 9.10 3.51 NA 24.660 8.000 22.48 0.260 67.56 6 NA 0.00 13.63

Biotechnology & Drugs GLFD Guilford Pharmaceuticals NASD Healthcare 106.830 NA NA 2.30 2.89 NA 46.450 35.300 81.36 0.840 24.00 0 NA 3.67 4.24

Biotechnology & Drugs HTI Halozyme Therapeutics, Inc. AMEX Healthcare 81.180 NA NA 1.64 5.44 NA 49.500 49.000 11.60 5.740 1.01 0 NA 0.00 10.23

Biotechnology & Drugs HNAB Hana Biosciences Inc OTC Healthcare 23.490 NA NA 1.65 4.67 NA 14.240 10.500 2.67 0.380 26.26 4 NA 0.37 3.04

Biotechnology & Drugs VGENQ Harvard Scientific Corp. OTC Healthcare 0.000 NA NA 0.00 NA NA 29.330 5.900 NA NA 79.88 NA NA NA NA

Biotechnology & Drugs HKRRF Hawker Resources Inc. (USA) OTC Healthcare 155.060 NA NA 3.60 1.55 NA 43.070 35.700 0.00 0.000 17.12 0 NA 0.43 0.56

Biotechnology & Drugs HDVY Health Discovery Corporation OTC Healthcare 0.000 NA NA 0.27 16.97 NA 0.000 0.000 NA NA 56.96 NA NA 1.79 0.22

Biotechnology & Drugs HESG Health Sciences Group, Inc. OTC Healthcare 20.530 NA NA 1.26 NA NA 16.300 8.400 NA NA 48.45 NA NA NA 0.39

Biotechnology & Drugs HCTL Healthcare Technologies NASD Healthcare 5.970 NA NA 0.78 NA NA 7.650 2.500 0.21 0.000 67.32 0 NA NA NA

Biotechnology & Drugs HXBM Helix BioMedix, Inc. OTC Healthcare 25.970 NA NA 1.55 6.16 NA 16.750 14.200 NA NA 15.24 NA NA 0.00 24.26

Biotechnology & Drugs HEMA HemaCare Corporation OTC Healthcare 11.500 NA NA 1.44 2.40 7.62 7.990 7.400 1.11 0.010 7.34 -1 NA 0.22 1.77

Biotechnology & Drugs HMGN Hemagen Diagnostics, Inc. OTC Healthcare 5.480 NA NA 0.36 459.92 NA 15.100 12.300 0.28 0.000 18.44 0 NA 311.75 3.32

Biotechnology & Drugs HEB Hemispherx BioPharma, Inc AMEX Healthcare 74.180 NA NA 1.50 3.27 NA 49.450 42.800 3.37 -1.340 13.45 4 NA 0.13 5.85

Biotechnology & Drugs HMSL Hemosol Corp. (USA) NASD Healthcare 31.430 NA NA 0.55 0.53 NA 57.150 48.000 6.95 0.040 16.00 0 NA 0.28 0.51

Biotechnology & Drugs HSKA Heska Corporation NASD Healthcare 36.880 NA NA 0.75 13.71 NA 49.170 18.100 38.22 -0.480 63.19 -1 NA 4.20 1.14

Biotechnology & Drugs HITK Hi-Tech Pharmacal Co. NASD Healthcare 170.260 1.02 27.00 21.98 2.51 25.53 7.750 6.800 35.13 0.070 12.21 -1 NA 0.00 6.35

Biotechnology & Drugs HEPH Hollis-Eden Pharmaceuticals Inc. NASD Healthcare 135.880 -0.07 75.00 7.05 2.33 NA 19.290 17.300 33.12 0.140 10.31 0 NA 0.00 12.42

Biotechnology & Drugs HSP Hospira, Inc. NYSE Healthcare 5,070.300 2.94 6.75 32.27 5.13 16.77 157.120 147.700 62.80 10.200 6.00 -1 NA 0.71 2.24

Biotechnology & Drugs HGSI Human Genome Sciences NASD Healthcare 1,201.750 NA NA 9.22 1.83 NA 130.340 127.000 83.15 8.600 2.54 -2 NA 0.77 10.18

Biotechnology & Drugs HBY Hybridon, Inc. AMEX Healthcare 65.430 NA NA 0.59 4.17 NA 110.900 84.300 6.01 -1.640 23.99 4 NA 0.00 8.01

Biotechnology & Drugs ICGN Icagen, Inc. NASD Healthcare 136.380 NA NA 6.36 0.49 NA 21.440 5.000 0.00 0.000 76.68 4 NA 0.06 6.73

Biotechnology & Drugs ICLR ICON plc (ADR) NASD Healthcare 520.000 1.23 17.50 37.52 2.20 35.94 13.860 13.600 66.50 0.910 1.87 0 NA 0.04 1.93

Biotechnology & Drugs ICOR Icoria, Inc. NASD Healthcare 12.710 NA NA 0.35 0.91 NA 36.320 32.500 5.70 -6.220 10.53 1 NA 0.31 0.79

Biotechnology & Drugs ICOS ICOS Corporation NASD Healthcare 1,433.650 -0.47 44.00 22.46 218.93 NA 63.830 63.500 63.81 -1.610 0.52 -7 NA 42.69 6.18

Biotechnology & Drugs IDBE ID Biomedical Corporation (USA) NASD Healthcare 643.030 NA NA 15.26 3.36 NA 42.140 39.600 19.20 3.760 6.02 0 NA 0.23 1.39

Biotechnology & Drugs IDIX Idenix Pharmaceuticals, Inc. NASD Healthcare 954.400 -0.29 44.00 19.85 8.71 NA 48.080 12.000 14.93 0.060 75.04 0 NA 0.03 3.35

Biotechnology & Drugs IDXX IDEXX Laboratories, Inc. NASD Healthcare 1,782.350 1.74 13.83 54.16 4.51 24.79 32.910 32.900 92.00 1.540 0.00 -4 NA 0.01 3.02

Biotechnology & Drugs IG IGI, Inc. AMEX Healthcare 16.210 NA NA 1.40 4.23 NA 11.580 8.300 3.49 0.050 28.34 0 NA 0.00 2.50

Biotechnology & Drugs ILXO ILEX Oncology, Inc. NASD Healthcare 984.270 NA NA 25.05 5.74 NA 39.290 38.700 0.00 0.000 1.51 -15 NA 0.12 4.23

Biotechnology & Drugs IMCL ImClone Systems Incorporated NASD Healthcare 2,875.160 1.16 16.67 34.50 16.02 28.94 83.340 66.500 71.18 5.960 20.20 -20 NA 3.36 3.50

Biotechnology & Drugs ICRP IMCOR Pharmaceutical Co. OTC Healthcare 8.210 NA NA 2.05 0.68 NA 4.000 2.030 NA NA 49.29 NA NA 0.10 0.32

Biotechnology & Drugs IME IMI International Medical Innov. (USA) AMEX Healthcare 68.160 NA NA 3.20 19.76 NA 21.300 18.700 4.04 0.070 12.20 0 NA 0.00 20.36

Biotechnology & Drugs IMM Immtech International, Inc. AMEX Healthcare 136.570 NA NA 12.42 38.92 NA 11.000 8.400 9.12 0.070 23.61 -1 NA 0.00 4.20

Biotechnology & Drugs ICCC ImmuCell Corporation NASD Healthcare 11.750 NA NA 4.26 1.56 NA 2.760 2.200 2.10 -0.010 20.23 0 NA 0.00 24.60

Biotechnology & Drugs IMMFF Immune Network Ltd. OTC Healthcare 0.150 NA NA 0.01 NA NA 20.920 12.800 NA NA 38.81 NA NA NA 0.05

Biotechnology & Drugs IMGN ImmunoGen, Inc. NASD Healthcare 213.330 -1.03 15.00 5.23 2.31 NA 40.790 40.200 36.51 -0.100 1.35 -3 NA 0.00 12.09

Biotechnology & Drugs IMMU Immunomedics, Inc. NASD Healthcare 131.400 NA NA 2.43 8.65 NA 54.070 43.400 28.76 -0.690 19.74 0 NA 0.95 3.46

Biotechnology & Drugs IPXL Impax Laboratories Inc. NASD Healthcare 935.760 2.86 23.80 16.00 10.84 2,000.00 58.480 40.000 62.46 2.170 31.61 7 NA 1.25 4.44

Biotechnology & Drugs INCY Incyte Corporation NASD Healthcare 504.450 NA NA 6.83 7.22 NA 73.860 55.400 85.52 10.820 8.95 2 NA 4.82 15.29





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BioTech Industry 31Mar05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs IDEV Indevus Pharmaceuticals NASD Healthcare 130.580 NA NA 2.78 NA NA 46.970 40.800 45.18 3.030 13.14 -6 NA NA 4.31

Biotechnology & Drugs INHX Inhibitex, Inc. NASD Healthcare 152.810 NA NA 6.09 2.73 NA 25.090 10.800 19.51 1.180 56.96 16 NA 0.06 9.28

Biotechnology & Drugs INKP InKine Pharmaceutical Company, Inc. NASD Healthcare 151.170 NA NA 3.10 10.59 53.45 48.770 47.900 42.87 1.860 1.82 -5 NA 0.00 5.64

Biotechnology & Drugs ISV Insite Vision Inc. AMEX Healthcare 30.560 NA NA 0.49 4.60 NA 62.370 50.800 10.64 0.120 18.55 0 NA 0.05 5.64

Biotechnology & Drugs INSM Insmed Incorporated NASD Healthcare 32.650 NA NA 0.85 6.65 NA 38.410 35.800 25.56 3.050 6.80 1 NA 0.00 1.37

Biotechnology & Drugs ISPH Inspire Pharmaceuticals, Inc. NASD Healthcare 341.590 NA NA 8.16 2.28 NA 41.860 41.200 85.47 4.090 1.58 -8 NA 0.01 11.50

Biotechnology & Drugs INB Integrated BioPharma, Inc. AMEX Healthcare 66.860 NA NA 5.30 3.62 NA 12.620 5.900 2.85 0.030 53.23 -4 NA 0.23 2.00

Biotechnology & Drugs IFSC Interferon Sciences, Inc. OTC Healthcare 1.490 NA NA 0.04 0.82 1.43 37.340 19.800 0.46 0.130 43.49 0 NA 0.12 3.13

Biotechnology & Drugs ITMN InterMune, Inc. NASD Healthcare 358.420 NA NA 11.00 10.93 NA 32.580 28.600 82.96 0.370 12.22 32 NA 5.18 3.75

Biotechnology & Drugs INIS International Isotopes Inc. OTC Healthcare 17.500 NA NA 0.11 20.47 NA 159.070 101.300 NA NA 36.32 NA NA 1.43 6.39

Biotechnology & Drugs IPA Interpharm Holdings, Inc. AMEX Healthcare 38.450 NA NA 1.54 1.65 38.50 24.970 18.700 3.66 0.010 25.10 1 NA 0.37 2.46

Biotechnology & Drugs IBCL Int'l BioChemical Industries, Inc. OTC Healthcare 0.110 NA NA 0.00 NA NA 94.160 92.500 0.01 0.000 1.77 0 NA NA 0.02

Biotechnology & Drugs IBPI IntraBiotics Pharmaceuticals NASD Healthcare 32.640 NA NA 3.60 0.66 NA 9.070 7.300 56.44 -0.290 19.50 0 NA 0.00 75.54

Biotechnology & Drugs INGN Introgen Therapeutics, Inc NASD Healthcare 214.280 NA NA 7.89 7.51 NA 27.160 16.700 21.38 3.460 39.84 0 NA 0.26 5.66

Biotechnology & Drugs IMA Inverness Medical Innovations, Inc. AMEX Healthcare 488.760 2.61 25.00 23.50 1.77 NA 20.800 9.200 51.29 1.980 55.76 0 NA 0.70 1.78

Biotechnology & Drugs IVRO InVitro International OTC Healthcare 0.220 NA NA 0.02 0.53 15.00 14.510 9.000 NA NA 37.96 NA NA 0.00 9.37

Biotechnology & Drugs IVGN Invitrogen Corporation NASD Healthcare 3,571.900 1.32 15.22 69.20 1.86 42.58 51.620 51.200 95.00 2.510 0.81 2 NA 0.69 6.79

Biotechnology & Drugs IOX IOMED, Inc. AMEX Healthcare 14.030 NA NA 2.13 4.80 16.64 6.590 5.000 3.25 -0.020 24.07 0 NA 0.17 7.18

Biotechnology & Drugs ISIS ISIS Pharmaceuticals, Inc. NASD Healthcare 221.660 NA NA 3.87 NA NA 57.280 51.400 53.74 3.930 10.31 -24 NA NA 2.89

Biotechnology & Drugs ILE Isolagen, Inc. AMEX Healthcare 190.080 NA NA 6.29 6.55 NA 30.220 27.500 46.03 1.040 9.00 -2 NA 3.11 13.73

Biotechnology & Drugs ISTA ISTA Pharmaceuticals NASD Healthcare 253.830 -0.35 25.00 9.88 12.48 NA 25.690 13.600 63.88 -0.360 33.20 -52 NA 0.00 2.81

Biotechnology & Drugs ITER IT&E International Group OTC Healthcare 7.790 NA NA 0.41 13.03 NA 19.000 18.800 NA NA 1.05 NA NA 2.49 1.18

Biotechnology & Drugs IVX IVAX Corporation AMEX Healthcare 5,160.870 1.05 23.65 19.77 3.46 26.50 261.050 203.600 55.22 6.640 22.01 7 NA 0.76 2.63

Biotechnology & Drugs KNDL Kendle International Inc. NASD Healthcare 152.190 NA NA 11.50 1.48 43.40 13.230 11.000 61.60 -0.020 17.20 -16 NA 0.10 1.75

Biotechnology & Drugs KERX Keryx Biopharmaceuticals NASD Healthcare 415.950 NA NA 13.36 9.78 NA 31.130 21.300 55.57 1.020 31.44 -6 NA 0.00 12.75

Biotechnology & Drugs KG King Pharmaceuticals NYSE Healthcare 2,008.720 0.98 10.09 8.31 1.09 NA 241.720 239.900 76.09 11.490 0.76 0 NA 0.19 1.64

Biotechnology & Drugs KOSP KOS Pharmaceuticals, Inc. NASD Healthcare 1,678.570 0.71 22.73 41.68 3.85 13.11 40.270 19.300 38.49 2.820 52.08 -6 NA 0.04 2.62

Biotechnology & Drugs KOSN Kosan Biosciences Incorporated NASD Healthcare 119.290 NA NA 4.10 1.72 NA 29.100 22.100 53.53 -0.470 24.05 0 NA 0.06 5.64

Biotechnology & Drugs KV.A K-V Pharmaceutical Company NYSE Healthcare 1,141.880 1.41 17.70 23.20 3.90 26.85 49.220 10.540 69.62 7.070 23.65 -1 NA 0.74 8.91

Biotechnology & Drugs LJPC La Jolla Pharmaceutical Company NASD Healthcare 51.630 NA NA 0.70 1.66 NA 73.760 72.900 27.23 -9.910 1.17 1 NA 0.06 3.78

Biotechnology & Drugs LCI Lannett Company, Inc. AMEX Healthcare 153.770 NA NA 6.30 1.45 17.36 24.410 10.200 4.31 -0.040 58.10 2 NA 0.11 8.73

Biotechnology & Drugs LSBC Large Scale Biology Corp. NASD Healthcare 28.210 NA NA 0.90 2.02 NA 31.350 25.100 8.53 0.090 19.93 0 NA 0.02 3.15

Biotechnology & Drugs LCAR Lescarden Inc. OTC Healthcare 10.740 NA NA 0.36 NA NA 29.830 20.100 0.06 -0.400 32.62 0 NA NA 0.59

Biotechnology & Drugs LEXG Lexicon Genetics Incorporated NASD Healthcare 324.680 -0.40 15.00 5.11 2.67 NA 63.540 49.900 53.16 1.330 21.46 -2 NA 0.31 2.55

Biotechnology & Drugs LIFC LifeCell Corporation NASD Healthcare 253.570 0.56 68.00 8.90 4.09 39.91 28.490 28.200 62.56 3.480 0.49 0 NA 0.00 5.62

Biotechnology & Drugs LCBM Lifecore Biomedical, Inc. NASD Healthcare 231.160 0.71 45.00 17.81 4.37 50.74 12.980 12.000 47.85 0.900 7.54 -1 NA 0.10 6.45

Biotechnology & Drugs LGNDE Ligand Pharmaceuticals NASD Healthcare 423.630 -31.12 36.10 5.73 10.33 NA 73.930 69.500 95.00 4.810 6.00 1 NA 4.25 1.75

Biotechnology & Drugs LIPD Lipid Sciences, Inc. NASD Healthcare 100.050 NA NA 4.05 5.97 NA 24.700 14.700 5.23 0.120 40.59 -3 NA 0.00 8.58

Biotechnology & Drugs LRP Lorus Therapeutics Inc. (USA) AMEX Healthcare 103.080 NA NA 0.60 6.58 NA 171.800 170.100 1.25 0.430 0.99 0 NA 0.17 4.43

Biotechnology & Drugs LMNX Luminex Corporation NASD Healthcare 234.810 NA NA 7.53 5.27 NA 31.180 28.500 37.17 0.770 8.60 0 NA 0.00 8.21

Biotechnology & Drugs MCHM MacroChem Corporation NASD Healthcare 15.140 NA NA 0.39 1.89 NA 38.830 36.100 25.17 -0.490 7.02 0 NA 0.00 9.00

Biotechnology & Drugs MHTT Manhattan Pharmaceuticals, Inc. OTC Healthcare 42.690 NA NA 1.55 6.88 NA 27.540 21.300 6.65 0.000 22.66 34 NA 0.00 5.04

Biotechnology & Drugs MTEX Mannatech, Inc. NASD Healthcare 528.650 NA NA 19.55 9.40 27.46 27.040 15.700 16.45 1.410 41.94 -15 0.72 0.00 1.69

Biotechnology & Drugs MNKD MannKind Corporation NASD Healthcare 466.830 NA NA 14.23 3.10 NA 32.810 6.300 12.87 0.220 50.87 1 NA 0.00 7.35

Biotechnology & Drugs MSHL Marshall Edwards, Inc. NASD Healthcare 474.860 NA NA 8.34 23.35 NA 56.940 6.800 0.79 0.120 88.06 0 NA 0.00 8.29

Biotechnology & Drugs MATK Martek Biosciences Corp. NASD Healthcare 1,827.760 1.08 48.00 58.19 4.17 35.08 31.410 30.200 90.43 2.220 3.85 2 NA 0.16 3.51

Biotechnology & Drugs MZT Matritech, Inc. AMEX Healthcare 43.440 NA NA 1.02 8.35 NA 42.590 41.900 7.14 -0.220 1.62 0 NA 0.36 2.32

Biotechnology & Drugs MTXX Matrixx Initiatives, Inc. NASD Healthcare 108.760 0.52 33.00 11.37 2.44 21.87 9.570 9.200 30.50 0.610 3.82 -5 NA 0.00 2.54

Biotechnology & Drugs MAXM Maxim Pharmaceuticals NASD Healthcare 50.270 NA NA 1.76 1.15 NA 28.560 28.500 22.98 -2.700 0.02 0 NA 0.02 5.48

Biotechnology & Drugs MAXY Maxygen, Inc. NASD Healthcare 303.340 NA NA 8.58 1.45 NA 35.350 22.800 35.25 1.280 35.52 -9 NA 0.01 14.18

Biotechnology & Drugs MDZ MDS Inc. (USA) NYSE Healthcare 2,058.800 1.16 15.00 14.53 1.64 NA 141.690 94.900 50.98 17.110 33.02 0 0.74 0.33 1.86

Biotechnology & Drugs MEDX Medarex, Inc. NASD Healthcare 788.080 NA NA 7.13 5.69 NA 110.530 100.000 55.53 6.160 9.53 -6 NA 2.77 7.51

Biotechnology & Drugs MLSC Medical Discoveries, Inc. OTC Healthcare 16.730 NA NA 0.16 NA NA 104.580 85.800 0.00 -0.020 17.96 0 NA NA 0.13

Biotechnology & Drugs MRX Medicis Pharmaceutical Corporation NYSE Healthcare 1,640.010 0.93 22.38 29.98 3.66 28.83 54.700 53.700 95.00 3.430 1.75 -4 0.40 1.02 7.94

Biotechnology & Drugs MCU Medicure Inc. (USA) AMEX Healthcare 39.990 NA NA 0.60 3.12 NA 66.650 60.600 6.67 -0.650 9.07 0 NA 0.00 9.66

Biotechnology & Drugs MHUT Medi-Hut Co., Inc. OTC Healthcare 0.650 NA NA 0.05 0.04 0.44 14.470 10.400 0.00 0.000 28.11 2 NA 0.00 2.66

Biotechnology & Drugs MEDI MedImmune, Inc. NASD Healthcare 5,922.210 3.03 21.48 23.81 3.53 NA 248.730 247.400 84.81 11.880 0.53 -2 NA 0.30 1.91

Biotechnology & Drugs TOX MEDTOX Scientific, Inc. AMEX Healthcare 60.280 NA NA 8.00 1.60 34.33 7.540 7.000 33.10 0.470 7.10 -1 NA 0.16 1.24

Biotechnology & Drugs MEMY Memory Pharmaceuticals Corp. NASD Healthcare 89.560 NA NA 4.38 3.27 NA 20.450 13.300 28.93 -0.730 34.96 -32 NA 0.06 6.37

Biotechnology & Drugs VIVO Meridian Bioscience, Inc. NASD Healthcare 233.200 1.75 12.50 14.90 6.12 24.07 15.650 11.500 33.61 1.250 26.52 -26 3.22 0.43 2.24

Biotechnology & Drugs MBRX Metabasis Therapeutics, Inc. NASD Healthcare 61.670 NA NA 3.40 1.31 NA 18.140 5.000 31.67 0.620 72.43 1 NA 0.05 11.19

Biotechnology & Drugs MOGN MGi Pharma, Inc. NASD Healthcare 1,805.560 1.08 32.50 25.27 15.68 NA 71.450 66.800 92.57 6.260 0.35 -4 NA 2.27 5.82

Biotechnology & Drugs MLAR Micro Laboratories, Inc. OTC Healthcare 1.670 NA NA 0.03 NA NA 49.960 9.500 NA NA 80.98 NA NA NA 0.00

Biotechnology & Drugs MII MicroIslet, Inc. AMEX Healthcare 55.900 NA NA 1.41 5.36 NA 39.650 34.100 6.16 -0.180 13.99 0 NA 0.00 38.48

Biotechnology & Drugs MLNM Millennium Pharmaceuticals, Inc. NASD Healthcare 2,576.190 -1.08 22.80 8.42 1.14 NA 305.960 302.300 68.00 12.490 1.21 0 NA 0.10 3.74





492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 31Mar05 32 of 45 10/24/2011 3:30 PM

BioTech Industry 31Mar05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs MRVT Miravant Medical Technologies OTC Healthcare 31.020 NA NA 0.85 NA NA 36.500 32.500 9.09 0.000 10.95 0 NA NA 5.10

Biotechnology & Drugs MNTA Momenta Pharmaceuticals, Inc. NASD Healthcare 215.070 NA NA 8.47 3.53 NA 25.390 5.400 19.06 0.350 78.73 3 NA 0.01 16.26

Biotechnology & Drugs MUCL MultiCell Technologies, Inc. OTC Healthcare 50.870 NA NA 0.34 18.14 NA 149.630 96.400 0.01 0.000 35.57 0 NA 0.18 1.81

Biotechnology & Drugs MYL Mylan Laboratories Inc. NYSE Healthcare 4,770.970 2.05 11.99 17.72 2.63 20.28 269.240 231.000 73.17 16.670 14.20 0 0.68 0.01 8.49

Biotechnology & Drugs MYMX Mymetics Corporation OTC Healthcare 16.610 NA NA 0.25 NA NA 66.450 55.200 0.48 -0.350 16.93 0 NA NA 0.03

Biotechnology & Drugs MYOG Myogen, Inc. NASD Healthcare 282.170 NA NA 7.89 2.63 NA 35.760 22.000 56.38 1.660 38.48 6 NA 0.02 7.51

Biotechnology & Drugs MYGN Myriad Genetics, Inc. NASD Healthcare 565.460 NA NA 18.39 3.67 NA 30.750 28.300 75.84 1.370 7.96 -3 NA 0.00 6.29

Biotechnology & Drugs NABI Nabi Biopharmaceuticals NASD Healthcare 738.470 NA NA 12.48 2.57 NA 59.170 58.200 76.22 2.350 1.66 0 NA 0.08 2.52

Biotechnology & Drugs NSTK Nastech Pharmaceutical NASD Healthcare 177.160 NA NA 9.88 3.04 NA 17.930 12.700 24.58 2.500 29.17 -9 NA 0.20 4.47

Biotechnology & Drugs NHCT National Healthcare Technology, Inc. OTC Healthcare 0.200 NA NA 2.50 NA NA 0.080 0.020 NA NA 81.01 NA NA NA NA

Biotechnology & Drugs NTOL Natrol, Inc. NASD Healthcare 39.540 NA NA 2.96 1.05 22.09 13.360 4.300 37.65 0.210 67.81 -6 NA 0.20 2.95

Biotechnology & Drugs NAII Natural Alternatives International, Inc. NASD Healthcare 40.080 NA NA 6.76 1.55 12.57 5.930 4.600 25.34 0.680 22.77 6 NA 0.17 2.18

Biotechnology & Drugs NAWL Naturewell, Inc. OTC Healthcare 1.190 NA NA 0.01 NA NA 118.820 72.200 0.00 0.000 38.99 -1 NA NA 0.03

Biotechnology & Drugs NTY NBTY, Inc. NYSE Healthcare 1,685.620 0.97 14.00 25.09 2.47 14.68 67.180 56.600 80.44 8.590 15.75 0 NA 0.45 2.80

Biotechnology & Drugs NEOG Neogen Corporation NASD Healthcare 119.990 1.18 16.50 14.79 2.32 22.79 8.110 7.000 29.52 0.190 13.72 -11 NA 0.05 4.31

Biotechnology & Drugs NEOL NeoPharm, Inc. NASD Healthcare 182.790 NA NA 7.77 3.12 NA 23.530 17.100 72.16 2.330 27.31 5 NA 0.00 7.01

Biotechnology & Drugs NEOP Neoprobe Corporation OTC Healthcare 26.810 NA NA 0.46 4.34 NA 58.290 54.600 0.61 0.000 6.33 2 NA 0.00 11.32

Biotechnology & Drugs NERX NeoRx Corporation NASD Healthcare 30.550 NA NA 0.99 1.17 NA 30.860 28.000 6.63 0.130 9.27 0 NA 0.17 11.71

Biotechnology & Drugs NTEC Neose Technologies, Inc. NASD Healthcare 84.580 NA NA 2.58 1.05 NA 32.780 28.800 47.83 -0.090 12.15 1 NA 0.30 4.02

Biotechnology & Drugs NTII Neurobiological Tech. NASD Healthcare 90.090 NA NA 3.33 4.05 NA 27.050 24.000 25.70 0.490 11.29 -1 NA 0.00 4.44

Biotechnology & Drugs NRMX Neurochem Inc. (USA) NASD Healthcare 360.660 NA NA 11.91 10.72 NA 30.280 19.900 21.25 -1.230 34.28 0 NA 0.26 3.02

Biotechnology & Drugs NBIX Neurocrine Biosciences, Inc. NASD Healthcare 1,392.900 -1.60 25.00 38.06 3.53 NA 36.600 35.000 91.28 2.080 4.36 -1 NA 0.17 5.27

Biotechnology & Drugs NRGN Neurogen Corporation NASD Healthcare 244.330 NA NA 7.08 1.62 NA 34.510 26.000 36.89 0.150 24.66 -3 NA 0.09 14.88

Biotechnology & Drugs NRGX Neurologix, Inc. OTC Healthcare 53.660 NA NA 2.15 13.06 NA 24.960 15.100 27.62 0.060 39.50 -5 NA 0.01 12.04

Biotechnology & Drugs NRPH New River Pharmaceuticals, Inc. NASD Healthcare 452.950 -0.67 40.00 25.50 16.02 NA 17.760 4.200 16.18 0.500 76.36 0 NA 0.00 15.28

Biotechnology & Drugs BBAL New York Health Care, Inc. OTC Healthcare 34.480 NA NA 1.05 4.98 NA 32.840 29.200 0.00 0.000 11.08 0 NA 0.00 0.91

Biotechnology & Drugs NEXM NexMed, Inc. NASD Healthcare 52.190 NA NA 1.13 6.09 NA 46.190 44.000 23.17 -0.390 4.73 5 NA 0.83 3.25

Biotechnology & Drugs NTMD NitroMed, Inc. NASD Healthcare 523.770 NA NA 17.31 3.81 NA 30.260 13.700 64.50 4.240 54.72 -4 NA 0.00 11.79

Biotechnology & Drugs NASIE North American Scientific, Inc. NASD Healthcare 58.300 -0.61 20.00 3.60 0.89 NA 16.200 12.800 49.15 0.060 20.97 0 NA 0.00 1.68

Biotechnology & Drugs NFLD Northfield Laboratories NASD Healthcare 242.450 NA NA 11.25 7.25 NA 21.550 19.500 17.89 1.420 10.20 0 NA 0.00 18.90

Biotechnology & Drugs NWBT Northwest Biotherapeutics OTC Healthcare 4.850 NA NA 0.26 NA NA 19.030 10.600 0.00 0.000 25.90 0 NA NA 0.03

Biotechnology & Drugs NVAX Novavax, Inc. NASD Healthcare 56.120 NA NA 1.41 1.68 NA 39.800 31.400 13.12 -0.270 10.06 -5 NA 1.12 2.79

Biotechnology & Drugs NOVN Noven Pharmaceuticals, Inc. NASD Healthcare 398.660 1.03 22.50 16.96 3.09 36.71 23.510 23.300 84.47 2.400 0.88 -1 NA 0.00 3.15

Biotechnology & Drugs NVO Novo Nordisk A/S (ADR) NYSE Healthcare 18,538.330 2.44 8.93 55.82 NA 21.53 332.110 236.600 2.17 1.850 28.76 0 1.54 NA NA

Biotechnology & Drugs NVGN Novogen Limited (ADR) NASD Healthcare 367.550 NA NA 19.00 8.21 NA 19.340 16.240 2.13 0.070 16.05 0 NA 0.02 10.04

Biotechnology & Drugs NPSP NPS Pharmaceuticals, Inc. NASD Healthcare 489.300 NA NA 12.62 NA NA 38.770 37.800 92.57 -0.620 2.33 -24 NA NA 8.10

Biotechnology & Drugs NPHC Nutra Pharma Corp. OTC Healthcare 18.390 NA NA 0.34 23.64 NA 54.100 47.600 NA NA 12.01 NA NA 0.13 0.10

Biotechnology & Drugs NUTR Nutraceutical Int'l Corp. NASD Healthcare 183.670 NA NA 15.86 2.46 14.28 11.580 11.000 72.27 0.890 5.02 -1 NA 0.07 3.09

Biotechnology & Drugs NXXI Nutrition 21, Inc. NASD Healthcare 48.710 NA NA 1.28 4.35 NA 38.050 34.500 1.90 0.030 9.34 2 NA 0.00 1.80

Biotechnology & Drugs NUVO Nuvelo, Inc. NASD Healthcare 273.020 NA NA 6.50 4.60 NA 42.000 38.500 43.02 2.100 8.34 1 NA 0.34 2.92

Biotechnology & Drugs NYMX Nymox Pharmaceutical Corporation NASD Healthcare 49.860 NA NA 1.98 41.67 NA 25.180 11.300 0.62 -0.150 54.91 0 NA 0.50 0.34

Biotechnology & Drugs ONCY Oncolytics Biotech, Inc. (USA) NASD Healthcare 128.270 NA NA 4.02 4.04 NA 31.920 31.600 10.16 3.130 0.99 0 NA 0.00 36.06

Biotechnology & Drugs ONCR Oncor, Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 33.550 24.500 0.22 0.020 26.98 0 NA NA 5.83

Biotechnology & Drugs ONXX Onyx Pharmaceuticals, Inc. NASD Healthcare 1,105.880 NA NA 31.35 6.14 NA 35.280 24.700 89.25 -1.010 29.98 -4 NA 0.11 13.72

Biotechnology & Drugs ONI Oragenics, Inc. AMEX Healthcare 33.520 NA NA 2.30 7.35 NA 14.570 6.400 1.26 0.180 56.08 1 NA 0.00 13.77

Biotechnology & Drugs ORCH Orchid Biosciences, Inc. NASD Healthcare 263.230 2.80 30.00 11.76 4.41 NA 22.380 22.200 55.31 0.760 0.82 3 NA 0.01 3.34

Biotechnology & Drugs ORPH Orphan Medical, Inc. NASD Healthcare 104.130 -0.37 36.28 9.11 9.65 NA 11.430 11.300 36.51 -0.300 1.14 -1 NA 0.00 2.33

Biotechnology & Drugs OSCI Oscient Pharmaceuticals Corporation NASD Healthcare 178.740 NA NA 2.34 1.55 NA 76.380 66.500 39.74 -0.850 12.94 -20 NA 1.53 5.76

Biotechnology & Drugs OSIP OSI Pharmaceuticals, Inc. NASD Healthcare 2,111.050 -0.79 29.00 41.34 3.91 NA 51.070 50.800 95.00 9.320 0.52 -65 NA 0.28 15.03

Biotechnology & Drugs OXGN OXiGENE, Inc. NASD Healthcare 68.190 NA NA 4.08 2.34 NA 16.710 16.000 12.59 -0.760 4.27 0 NA 0.00 11.67

Biotechnology & Drugs OXIS OXIS International, Inc. OTC Healthcare 14.460 NA NA 0.35 1.71 NA 41.310 20.500 0.21 0.030 50.37 0 NA 0.23 2.81

Biotechnology & Drugs PBME Pacific Biometrics, Inc. OTC Healthcare 16.170 NA NA 1.24 NA NA 13.050 7.200 0.00 0.000 45.57 -4 NA NA 1.09

Biotechnology & Drugs PHLI PacificHealth Laboratories, Inc. OTC Healthcare 6.240 NA NA 0.61 2.86 NA 10.240 6.700 0.00 0.000 34.55 -1 NA 0.21 2.05

Biotechnology & Drugs PTIE Pain Therapeutics, Inc. NASD Healthcare 221.800 NA NA 5.08 2.37 NA 43.660 33.200 46.92 4.320 23.96 1 NA 0.00 12.78

Biotechnology & Drugs PTN Palatin Technologies, Inc AMEX Healthcare 126.310 NA NA 2.34 7.13 NA 53.980 50.600 23.61 2.410 6.15 2 NA 0.00 3.24

Biotechnology & Drugs PGNT Paligent Inc. OTC Healthcare 3.570 NA NA 0.11 NA NA 32.490 14.600 0.09 0.000 55.06 0 NA NA 0.32

Biotechnology & Drugs PRX Par Pharmaceutical Companies, Inc NYSE Healthcare 1,135.520 0.95 15.44 33.44 2.74 42.01 33.960 33.900 95.00 5.720 0.17 1 NA 0.50 3.19

Biotechnology & Drugs PRLN Paracelsian, Inc. OTC Healthcare 0.310 NA NA 0.01 NA NA 23.950 16.000 0.69 0.000 33.21 0 NA NA 0.03

Biotechnology & Drugs PRXL PAREXEL International NASD Healthcare 616.330 1.27 18.33 23.50 2.27 40.03 26.230 26.100 95.00 0.850 0.48 -1 NA 0.00 1.73

Biotechnology & Drugs PPCO Penwest Pharmaceuticals NASD Healthcare 229.260 NA NA 12.36 3.40 NA 18.550 18.200 94.60 2.510 3.29 0 NA 0.00 14.48

Biotechnology & Drugs PPHM Peregrine Pharmaceuticals NASD Healthcare 222.330 NA NA 1.47 21.19 NA 151.240 142.600 13.56 1.430 5.71 -8 NA 0.07 3.02

Biotechnology & Drugs PRGO Perrigo Company NASD Healthcare 1,370.420 2.13 10.00 19.15 2.38 23.61 71.560 57.900 84.74 6.030 29.99 -8 0.84 0.02 2.87

Biotechnology & Drugs PHFR Pharmaceutical Formulations, Inc. OTC Healthcare 17.200 NA NA 0.20 NA NA 85.990 10.800 NA NA 87.44 NA NA NA 0.83

Biotechnology & Drugs PPDI Pharmaceutical Product Development, Inc. NASD Healthcare 2,739.030 1.30 19.55 48.45 4.32 27.86 56.530 48.100 79.61 -0.970 15.07 -2 NA 0.01 1.81

Biotechnology & Drugs PCOP Pharmacopeia Drug Discovery, Inc. NASD Healthcare 62.010 NA NA 5.04 1.42 NA 12.300 12.300 76.64 0.500 0.03 2 NA 0.00 4.09





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Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs PCYC Pharmacyclics, Inc. NASD Healthcare 158.530 NA NA 8.03 1.85 NA 19.740 19.500 69.54 1.100 1.23 -1 NA 0.00 22.19

Biotechnology & Drugs PFTR PharmaFrontiers Corp. OTC Healthcare 37.450 NA NA 4.99 65.34 NA 7.500 5.200 NA NA 30.71 NA NA 0.24 1.54

Biotechnology & Drugs PPRT PharmaPrint Inc. OTC Healthcare 0.050 NA NA 0.00 NA NA 23.980 22.500 NA NA 6.19 NA NA NA 0.06

Biotechnology & Drugs PHRM Pharmion Corporation NASD Healthcare 918.030 2.38 30.00 29.00 2.62 NA 31.660 17.700 64.83 1.520 44.06 4 NA 0.00 5.21

Biotechnology & Drugs PARS Pharmos Corporation NASD Healthcare 59.940 NA NA 0.63 1.28 NA 95.140 93.000 14.46 -0.770 2.25 -9 NA 0.10 5.90

Biotechnology & Drugs PLTT Pilot Therapeutics Holdings, Inc. OTC Healthcare 0.920 NA NA 0.08 NA NA 11.540 2.600 NA NA 77.48 NA NA NA 0.25

Biotechnology & Drugs PLRS Pluristem Life Systems, Inc. OTC Healthcare 8.710 NA NA 0.28 87.82 NA 31.110 23.000 NA NA 26.06 NA NA 0.14 0.71

Biotechnology & Drugs POTP Point Therapeutics, Inc. OTC Healthcare 88.750 NA NA 4.05 6.14 NA 21.910 20.000 21.06 0.530 8.73 0 NA 0.00 5.96

Biotechnology & Drugs POLXF Polydex Pharmaceuticals Limited NASD Healthcare 14.880 NA NA 4.89 1.73 8.43 3.040 2.200 1.02 -0.010 17.82 0 NA 0.14 3.58

Biotechnology & Drugs PROAQ Polymer Research Corp. of America OTC Healthcare 1.150 NA NA 0.54 3.67 NA 2.130 0.900 0.14 0.000 57.73 0 NA 6.88 0.69

Biotechnology & Drugs PWRM Power3 Medical Products, Inc. OTC Healthcare 33.620 NA NA 0.54 NA NA 62.250 9.300 0.00 -0.010 85.06 0 NA NA 0.10

Biotechnology & Drugs POZN POZEN Inc. NASD Healthcare 150.650 NA NA 5.21 4.74 NA 28.920 21.900 48.19 -0.130 24.26 1 NA 0.00 3.82

Biotechnology & Drugs PRAI PRA International NASD Healthcare 602.590 1.46 15.50 26.93 4.00 26.51 22.380 10.500 26.12 5.850 53.08 -11 NA 0.00 1.07

Biotechnology & Drugs PRCS Praecis Pharmaceuticals NASD Healthcare 55.040 NA NA 1.05 0.49 NA 52.420 50.200 52.39 -5.030 4.35 2 NA 0.00 9.45

Biotechnology & Drugs PRAN Prana Biotechnology Limited (ADR) NASD Healthcare 58.370 NA NA 3.49 1.35 NA 16.730 14.860 12.49 -0.010 11.15 0 NA 0.00 11.00

Biotechnology & Drugs PBIO Pressure BioSciences, Inc. NASD Healthcare 20.140 NA NA 2.93 0.80 NA 6.870 6.300 4.73 0.090 8.34 0 NA 0.00 5.45

Biotechnology & Drugs PGLAF Progen Industries Limited (USA) NASD Healthcare 82.510 NA NA 2.39 6.27 NA 34.520 30.700 0.03 -0.040 11.07 0 NA 0.01 11.71

Biotechnology & Drugs PGNX Progenics Pharmaceuticals NASD Healthcare 294.010 NA NA 16.81 8.79 NA 17.490 14.800 67.24 -0.280 15.38 -12 NA 0.00 4.35

Biotechnology & Drugs PRW Pro-Pharmaceuticals, Inc. AMEX Healthcare 75.120 NA NA 2.75 6.15 NA 27.320 20.900 2.69 -0.240 23.49 3 NA 0.00 20.63

Biotechnology & Drugs PDLI Protein Design Labs, Inc. NASD Healthcare 1,536.170 -0.65 94.00 15.99 3.72 NA 96.070 93.300 86.57 3.170 2.88 -24 NA 0.63 9.21

Biotechnology & Drugs PPTI Protein Polymer Technologies, Inc. OTC Healthcare 42.990 NA NA 1.09 NA NA 39.440 29.100 0.01 0.000 26.22 0 NA NA 0.18

Biotechnology & Drugs PPMD Protide Pharmaceuticals OTC Healthcare 0.810 NA NA 0.20 3.37 NA 4.030 3.400 NA NA 15.61 NA NA 0.30 2.61

Biotechnology & Drugs PVLS Provalis PLC (ADR) NASD Healthcare 34.390 NA NA 3.12 1.23 NA 11.020 9.150 0.03 0.000 16.99 0 NA 0.00 1.88

Biotechnology & Drugs PVCT Provectus Pharmaceuticals, Inc. OTC Healthcare 10.740 NA NA 0.70 1.14 NA 15.340 9.400 0.16 0.000 38.73 0 NA 0.14 0.51

Biotechnology & Drugs PMD Psychemedics Corp. AMEX Healthcare 68.090 NA NA 13.28 10.92 24.64 5.130 5.000 25.16 0.360 2.48 -3 2.41 0.00 3.33

Biotechnology & Drugs PURW Pure World, Inc. NASD Healthcare 14.200 NA NA 1.75 0.83 22.14 8.120 4.100 6.28 -0.060 49.51 0 NA 0.12 2.17

Biotechnology & Drugs QLTI QLT Inc. (USA) NASD Healthcare 1,200.990 0.84 19.86 12.86 1.38 NA 93.390 74.100 51.12 -6.340 20.65 -1 NA 0.20 14.39

Biotechnology & Drugs QSC Questcor Pharmaceuticals AMEX Healthcare 31.140 NA NA 0.61 8.57 NA 51.170 34.300 9.69 1.450 32.97 0 NA 0.38 1.54

Biotechnology & Drugs REGN Regeneron Pharmaceuticals NASD Healthcare 286.780 NA NA 5.11 1.56 7.92 56.120 33.500 49.74 -0.560 40.31 -13 NA 1.10 10.08

Biotechnology & Drugs RGN RegeneRx Biopharmaceut. AMEX Healthcare 93.530 NA NA 2.75 40.97 NA 34.010 16.600 3.11 -0.020 51.19 1 NA 0.00 8.82

Biotechnology & Drugs RNVS Renovis, Inc. NASD Healthcare 196.220 NA NA 8.07 2.38 NA 24.310 13.100 30.10 1.730 46.12 -10 NA 0.00 8.61

Biotechnology & Drugs RGEN Repligen Corporation NASD Healthcare 51.100 -0.91 15.00 1.70 2.07 NA 30.060 28.600 9.56 -0.750 4.90 3 NA 0.00 7.52

Biotechnology & Drugs RIGL Rigel Pharmaceuticals, Inc. NASD Healthcare 315.510 NA NA 16.04 6.03 NA 19.670 7.900 75.09 2.750 59.84 -9 NA 0.04 6.50

Biotechnology & Drugs STCX SalesTactix, Inc. OTC Healthcare 0.410 NA NA 0.06 NA NA 6.840 5.500 NA NA 19.54 NA NA NA NA

Biotechnology & Drugs SLXP Salix Pharmaceuticals Ltd NASD Healthcare 603.120 0.93 28.00 16.49 6.95 99.94 36.580 30.700 89.00 2.680 16.06 6 NA 0.00 4.30

Biotechnology & Drugs LIV Samaritan Pharmaceuticals, Inc. AMEX Healthcare 66.710 NA NA 0.51 11.09 NA 130.800 124.900 0.57 0.000 4.51 0 NA 0.00 9.02

Biotechnology & Drugs SGMO Sangamo Biosciences, Inc. NASD Healthcare 101.420 NA NA 4.00 3.12 NA 25.350 12.900 34.75 -1.160 49.12 -15 NA 0.00 14.64

Biotechnology & Drugs SGNC Sanguine Corporation OTC Healthcare 20.710 NA NA 0.26 NA 11.30 79.650 55.800 NA NA 29.94 NA NA NA 0.05

Biotechnology & Drugs SNY Sanofi-Aventis (ADR) NYSE Healthcare 119,517.720 129.11 0.13 42.34 6.99 20.04 2,822.810 2,145.400 3.64 30.580 24.00 0 1.96 0.05 2.74

Biotechnology & Drugs SNTS Santarus, Inc. NASD Healthcare 176.100 -0.06 30.00 4.86 1.50 NA 36.230 29.000 47.03 1.920 19.97 3 NA 0.00 11.51

Biotechnology & Drugs SVNT Savient Pharmaceuticals, Inc. NASD Healthcare 162.590 -6.73 20.00 2.69 1.05 NA 60.440 57.100 41.46 4.820 5.53 0 NA 0.04 1.58

Biotechnology & Drugs SCLN SciClone Pharmaceuticals NASD Healthcare 126.840 NA NA 2.84 2.30 NA 44.660 43.900 26.15 1.000 1.78 9 NA 0.10 5.69

Biotechnology & Drugs DDD SCOLR Pharma Inc. AMEX Healthcare 127.500 NA NA 4.18 12.30 NA 30.500 28.100 3.26 0.160 7.88 2 NA 0.01 14.97

Biotechnology & Drugs SGEN Seattle Genetics, Inc. NASD Healthcare 215.630 -0.34 15.00 5.14 2.08 NA 41.950 30.200 51.51 0.800 28.10 -13 NA 0.00 4.13

Biotechnology & Drugs STLT Select Therapeutics Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 17.560 15.000 NA NA 14.58 NA NA NA NA

Biotechnology & Drugs SNT Senesco Technologies, Inc. AMEX Healthcare 46.890 NA NA 3.40 12.14 NA 13.790 12.200 14.08 0.020 10.95 1 NA 0.00 7.37

Biotechnology & Drugs SNTKY Senetek PLC (ADR) OTC Healthcare 16.380 NA NA 0.27 NA NA 60.660 60.600 0.06 -0.200 0.10 2 NA NA 2.50

Biotechnology & Drugs SNMX Senomyx Inc. NASD Healthcare 302.940 NA NA 11.91 7.86 NA 25.440 17.000 56.56 0.990 33.17 -8 NA 0.00 8.06

Biotechnology & Drugs SGHL Sentigen Holding Corp. NASD Healthcare 34.890 NA NA 4.67 3.45 NA 7.470 5.000 1.07 0.000 33.07 0 NA 0.10 4.60

Biotechnology & Drugs SEPR Sepracor Inc. NASD Healthcare 5,950.680 NA NA 57.41 NA NA 103.650 97.500 95.00 14.340 5.94 0 NA NA 4.12

Biotechnology & Drugs SQNM Sequenom, Inc. NASD Healthcare 42.070 NA NA 1.06 1.11 NA 39.690 38.400 11.05 -2.380 3.25 0 NA 0.00 26.65

Biotechnology & Drugs SRLS SeraCare Life Sciences NASD Healthcare 121.950 NA NA 12.30 2.56 24.26 9.910 8.600 17.89 0.540 13.25 -1 NA 0.62 2.58

Biotechnology & Drugs SERO Serologicals Corporation NASD Healthcare 844.810 1.41 17.67 24.44 2.02 41.01 34.570 33.800 95.00 9.770 2.22 -7 NA 0.32 3.37

Biotechnology & Drugs SRA Serono S.A. (ADR) NYSE Healthcare 10,550.200 1.51 13.00 18.15 4.31 22.58 581.280 232.000 1.14 0.840 60.09 0 0.88 0.28 2.36

Biotechnology & Drugs SFCC SFBC International, Inc. NASD Healthcare 535.110 0.81 24.00 35.24 3.08 28.37 15.180 13.600 61.58 2.250 11.30 -8 NA 1.59 1.82

Biotechnology & Drugs SHPH Shaman Pharmaceuticals Inc. OTC Healthcare 0.010 NA NA 0.00 NA NA 103.460 46.600 0.11 0.000 54.96 0 NA NA 0.11

Biotechnology & Drugs SHPGY Shire Pharmaceuticals Group plc (ADR) NASD Healthcare 5,589.270 1.11 14.01 34.28 2.48 17.34 163.050 158.100 22.02 4.220 3.05 -1 0.50 0.02 4.47

Biotechnology & Drugs SIGA SIGA Technologies, Inc. NASD Healthcare 31.360 NA NA 1.28 4.12 NA 24.500 14.400 5.00 0.040 41.23 5 NA 0.00 3.68

Biotechnology & Drugs SVA Sinovac Biotech Ltd. AMEX Healthcare 98.900 NA NA 2.84 9.32 NA 34.820 14.600 0.07 0.020 58.07 0 NA 0.26 1.29

Biotechnology & Drugs RNAI Sirna Therapeutics, Inc. NASD Healthcare 122.050 NA NA 2.95 3.28 NA 41.370 13.300 49.09 1.030 67.85 0 NA 0.01 5.27

Biotechnology & Drugs SKYE SkyePharma plc (ADR) NASD Healthcare 628.470 NA NA 10.10 4.40 NA 62.220 60.980 0.48 -2.430 2.00 0 NA 1.01 0.54

Biotechnology & Drugs SLXA Solexa Limited NASD Healthcare 314.340 NA NA 9.04 7.30 NA 34.770 7.000 NA NA 79.87 NA NA 0.00 7.84

Biotechnology & Drugs SNUS Sonus Pharmaceuticals, Inc. NASD Healthcare 56.360 -0.56 6.50 2.64 2.31 NA 21.350 20.900 19.92 -1.080 2.10 0 NA 0.01 10.69

Biotechnology & Drugs DIAGF Spectral Diagnostics, Inc (USA) NASD Healthcare 12.770 NA NA 0.75 1.99 NA 17.130 15.400 0.00 0.000 10.13 0 NA 1.08 2.89

Biotechnology & Drugs SPPI Spectrum Pharmaceuticals, Inc. NASD Healthcare 91.500 NA NA 5.97 2.50 NA 15.330 14.100 28.53 0.650 8.00 0 NA 0.00 15.00





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BioTech Industry 31Mar05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs SLXCF Stellar Pharmaceuticals Inc. (USA) OTC Healthcare 40.590 NA NA 1.80 11.40 NA 22.550 13.600 NA NA 39.69 NA NA 0.00 5.36

Biotechnology & Drugs STEM StemCells, Inc. NASD Healthcare 194.530 NA NA 3.15 5.30 NA 61.760 58.100 8.19 -1.890 5.96 0 NA 0.05 12.26

Biotechnology & Drugs STGN Stratagene Corporation NASD Healthcare 193.960 1.51 15.00 8.81 3.51 21.97 22.020 3.900 14.48 -0.360 82.29 -3 NA 0.18 2.16

Biotechnology & Drugs SUPG SuperGen, Inc. NASD Healthcare 244.030 NA NA 4.86 3.39 NA 50.210 47.600 39.31 1.400 5.36 0 NA 0.00 3.85

Biotechnology & Drugs SWME Swiss Medica, Inc. OTC Healthcare 15.730 NA NA 0.26 10.40 NA 60.510 30.800 NA NA 49.10 NA NA 0.00 3.82

Biotechnology & Drugs SYMBA Symbollon Pharmaceuticals OTC Healthcare 7.850 NA NA 1.30 6.30 NA 6.040 4.700 0.00 -0.010 22.18 0 NA 0.00 9.36

Biotechnology & Drugs SBIO Synbiotics Corporation OTC Healthcare 2.380 NA NA 0.11 1.64 NA 21.610 8.900 1.18 0.000 58.81 -1 NA 1.01 1.82

Biotechnology & Drugs SYBD Synthetic Blood Int'l Inc OTC Healthcare 37.650 NA NA 0.30 95.40 NA 125.510 120.000 0.05 0.030 4.39 0 NA 0.00 0.31

Biotechnology & Drugs TNOX Tanox, Inc. NASD Healthcare 422.400 NA NA 9.60 1.88 NA 44.000 23.900 60.37 6.780 45.68 -4 NA 0.02 18.58

Biotechnology & Drugs TPPH Tapestry Pharmaceuticals, Inc. NASD Healthcare 20.400 NA NA 0.61 0.73 NA 33.440 29.300 12.19 0.020 12.37 2 NA 0.23 3.84

Biotechnology & Drugs TGEN Targeted Genetics Corp. NASD Healthcare 52.230 NA NA 0.61 1.05 NA 85.630 83.900 5.39 0.820 2.02 -3 NA 0.23 8.80

Biotechnology & Drugs TARO Taro Pharmaceutical Industries Ltd. NASD Healthcare 924.750 1.12 21.67 31.56 2.49 86.00 29.300 26.100 64.98 2.190 10.93 0 NA 0.73 2.55

Biotechnology & Drugs TCPI TCPI, Inc. OTC Healthcare 0.150 NA NA 0.00 0.01 NA 96.910 91.100 NA NA 5.99 NA NA 0.01 0.64

Biotechnology & Drugs TECH Techne Corporation NASD Healthcare 1,660.200 2.31 11.67 40.18 5.00 29.35 41.320 38.700 79.70 0.510 6.34 1 NA 0.05 11.40

Biotechnology & Drugs TELK Telik, Inc. NASD Healthcare 783.360 -0.16 54.00 15.08 5.23 NA 51.950 51.600 79.72 2.410 0.67 3 NA 0.02 7.88

Biotechnology & Drugs TRCA Tercica, Inc. NASD Healthcare 187.390 NA NA 7.63 3.23 NA 24.560 8.800 29.98 0.670 64.17 5 NA 0.00 10.42

Biotechnology & Drugs TEVA NASD

Teva Pharmaceutical Industries Ltd (ADR) Healthcare 18,947.290 0.96 20.01 30.99 3.52 75.22 611.400 562.500 50.83 30.810 8.00 0 0.88 0.39 1.91

Biotechnology & Drugs IMNR The Immune Response Corp. NASD Healthcare 37.910 NA NA 0.78 NA NA 48.600 17.000 3.89 0.040 46.92 0 NA 0.61 3.97

Biotechnology & Drugs MDCO The Medicines Company NASD Healthcare 1,090.270 1.37 32.50 22.66 6.42 66.26 48.110 42.800 95.00 5.830 11.05 -22 NA 0.00 5.97

Biotechnology & Drugs QGLY The Quigley Corporation NASD Healthcare 96.120 NA NA 8.26 5.00 236.00 11.640 8.800 1.98 -0.060 24.38 -2 NA 0.00 5.47

Biotechnology & Drugs TGX Theragenics Corporation NYSE Healthcare 103.280 NA NA 3.44 0.75 NA 30.020 29.500 54.60 -0.860 1.74 1 NA 0.00 24.52

Biotechnology & Drugs THRX Theravance, Inc NASD Healthcare 968.060 NA NA 18.25 5.07 NA 53.040 6.200 22.15 11.750 88.31 5 NA 0.13 10.98

Biotechnology & Drugs TWTI Third Wave Technologies NASD Healthcare 237.040 -2.23 25.00 5.76 3.77 NA 41.150 24.700 67.47 5.070 39.98 5 NA 0.16 3.51

Biotechnology & Drugs THLD Threshold Pharmaceuticals, Inc. NASD Healthcare 175.240 NA NA 5.99 NA NA 29.250 5.300 0.00 0.000 81.88 7 NA 0.01 13.48

Biotechnology & Drugs TBGU Tiens Biotech Group (USA), Inc. OTC Healthcare 356.670 NA NA 5.00 6.20 13.93 71.330 4.300 0.00 0.000 93.97 0 NA 0.19 10.42

Biotechnology & Drugs TTP Titan Pharmaceuticals AMEX Healthcare 71.800 NA NA 2.22 2.13 NA 32.340 31.700 21.19 -0.520 1.99 0 NA 0.00 10.19

Biotechnology & Drugs TRGNY Transgene (ADR) NASD Healthcare 82.090 NA NA 2.69 4.44 NA 30.470 7.270 0.00 0.000 76.13 0 NA 0.00 3.14

Biotechnology & Drugs TKTX Transkaryotic Therapies NASD Healthcare 868.100 NA NA 24.97 4.48 NA 34.770 27.700 75.33 0.930 20.29 0 NA 0.48 5.62

Biotechnology & Drugs TRMS Trimeris, Inc. NASD Healthcare 245.540 NA NA 11.26 8.13 NA 21.810 18.800 90.53 -0.420 13.79 1 NA 0.00 8.18

Biotechnology & Drugs TRIB Trinity Biotech plc (ADR) NASD Healthcare 118.260 NA NA 2.54 1.26 28.86 46.560 41.500 8.86 -0.010 10.87 0 NA 0.14 5.31

Biotechnology & Drugs TMGU Trinity Medical Group USA, Inc. OTC Healthcare 0.200 NA NA 0.01 NA NA 19.520 9.900 NA NA 49.28 NA NA NA 0.34

Biotechnology & Drugs TRPS Tripos, Inc. NASD Healthcare 38.570 NA NA 4.15 1.39 172.92 9.290 8.700 50.87 -0.020 6.38 0 NA 0.39 1.02

Biotechnology & Drugs UGNE Unigene Laboratories OTC Healthcare 137.260 NA NA 1.76 NA NA 77.990 73.200 0.27 0.000 6.14 -1 NA NA 0.26

Biotechnology & Drugs UTHR United Therapeutics Corporation NASD Healthcare 1,027.820 0.97 36.00 45.70 5.35 70.96 22.490 21.300 95.00 3.310 5.30 -61 NA 0.00 7.97

Biotechnology & Drugs UG United-Guardian, Inc. AMEX Healthcare 36.970 NA NA 7.50 2.75 14.94 4.930 2.800 11.72 0.010 43.21 -2 2.40 0.00 7.67

Biotechnology & Drugs VITXD V.I. Technologies, Inc. NASD Healthcare 115.360 NA NA 3.02 6.97 NA 38.200 29.800 NA NA 22.90 NA NA 0.00 0.94

Biotechnology & Drugs VRX Valeant Pharmaceuticals International NYSE Healthcare 1,894.490 4.25 22.50 22.52 3.98 NA 84.120 83.400 90.93 4.990 0.88 0 1.38 1.67 4.01

Biotechnology & Drugs VLTS Valentis, Inc. NASD Healthcare 34.840 NA NA 2.66 2.21 NA 13.100 9.800 39.14 -0.170 25.18 -20 NA 0.00 5.10

Biotechnology & Drugs VAPH Vaso Active Pharmaceuticals, Inc. OTC Healthcare 6.710 NA NA 0.65 2.63 NA 10.330 2.800 0.50 0.000 66.11 0 NA 0.00 6.09

Biotechnology & Drugs VXGN VaxGen, Inc. OTC Healthcare 312.970 NA NA 12.48 11.72 NA 25.080 23.100 30.34 -0.180 1.91 0 NA 0.00 1.47

Biotechnology & Drugs VNLS Vernalis plc (ADR) NASD Healthcare 174.110 NA NA 2.45 7.31 NA 71.060 49.750 2.82 1.990 29.99 0 NA 4.71 3.83

Biotechnology & Drugs VRTX Vertex Pharmaceuticals NASD Healthcare 751.700 NA NA 9.36 21.33 NA 80.310 78.600 77.71 1.580 2.23 -21 NA 9.67 2.65

Biotechnology & Drugs VIAC Viacell, Inc. NASD Healthcare 271.990 NA NA 7.54 NA NA 36.070 7.500 0.00 0.000 79.21 0 NA 0.55 1.51

Biotechnology & Drugs VICL Vical Incorporated NASD Healthcare 94.050 NA NA 4.00 1.13 NA 23.510 23.100 34.91 0.430 1.75 3 NA 0.13 7.66

Biotechnology & Drugs MICU Vicuron Pharmaceuticals, Inc. NASD Healthcare 955.550 NA NA 15.76 4.14 NA 60.630 56.400 71.32 -0.100 6.98 -4 NA 0.05 7.08

Biotechnology & Drugs VION Vion Pharmaceuticals, Inc. NASD Healthcare 187.780 NA NA 2.85 4.40 NA 65.890 64.200 46.91 2.650 2.56 0 NA 0.00 6.94

Biotechnology & Drugs VGNI Viragen International, Inc. OTC Healthcare 8.840 NA NA 0.12 1.48 NA 73.670 14.200 NA NA 80.72 NA NA 0.13 4.63

Biotechnology & Drugs VRA Viragen, Inc. AMEX Healthcare 24.870 NA NA 0.68 1.09 NA 36.570 35.800 5.76 1.550 2.10 3 NA 0.66 13.04

Biotechnology & Drugs VRAL Viral Genetics, Inc. OTC Healthcare 19.170 NA NA 0.24 6.36 NA 79.890 27.200 NA NA 65.95 NA NA 0.40 0.10

Biotechnology & Drugs VBAC Virbac Corporation OTC Healthcare 78.960 NA NA 3.55 2.25 33.49 22.240 8.100 2.61 -0.010 63.59 0 NA 0.30 3.94

Biotechnology & Drugs VLGC ViroLogic, Inc. NASD Healthcare 280.470 NA NA 2.39 3.82 NA 117.350 102.100 54.70 0.510 13.00 -1 NA 0.07 5.75

Biotechnology & Drugs VPHM ViroPharma Incorporated NASD Healthcare 62.550 NA NA 2.34 NA NA 26.730 23.800 46.14 4.710 0.95 8 NA NA 4.25

Biotechnology & Drugs VTLV Vital Living, Inc. OTC Healthcare 8.730 NA NA 0.11 0.32 NA 79.320 48.400 1.46 1.160 38.98 0 NA 0.11 0.63

Biotechnology & Drugs VVUS VIVUS, Inc. NASD Healthcare 114.290 NA NA 2.99 3.71 NA 38.220 37.100 42.24 0.280 2.94 4 NA 0.11 2.76

Biotechnology & Drugs VYRX Vyrex Corporation OTC Healthcare 1.020 NA NA 0.12 NA NA 8.490 7.400 NA NA 12.87 NA NA NA 0.28

Biotechnology & Drugs WPI Watson Pharmaceuticals NYSE Healthcare 3,380.640 1.98 11.31 30.73 1.50 24.20 110.010 104.900 82.27 8.780 4.65 -4 NA 0.26 5.36

Biotechnology & Drugs WFHCQ Women First HealthCare OTC Healthcare 0.030 NA NA 0.00 NA NA 26.660 16.000 0.33 0.000 39.98 0 NA NA 0.16

Biotechnology & Drugs XCYT Xcyte Therapies, Inc. NASD Healthcare 20.570 NA NA 1.23 0.68 NA 16.720 9.500 43.25 3.560 43.19 1 NA 0.13 6.15

Biotechnology & Drugs XKEM Xechem International, Inc OTC Healthcare 3.880 NA NA 0.02 NA NA 258.670 245.700 0.19 0.000 5.01 0 NA NA 0.51

Biotechnology & Drugs XNVA Xenova Group plc (ADR) NASD Healthcare 40.990 NA NA 0.95 0.62 NA 43.150 42.720 6.59 2.790 0.99 0 NA 0.01 3.25

Biotechnology & Drugs XOMA XOMA Limited NASD Healthcare 85.830 NA NA 1.00 NA NA 85.830 84.800 34.42 -2.650 1.19 0 NA NA 1.13

Biotechnology & Drugs XTRN Xtrana, Inc. OTC Healthcare 3.310 NA NA 0.20 1.12 3.39 16.530 13.800 0.09 0.000 16.53 0 NA 0.01 14.99

Biotechnology & Drugs YMI YM BioSciences Inc. (USA) AMEX Healthcare 89.350 NA NA 2.55 3.25 NA 35.040 34.700 11.56 3.950 0.97 0 NA 0.00 41.88

Biotechnology & Drugs ZILA Zila, Inc. NASD Healthcare 184.770 -0.99 32.50 4.04 4.12 NA 45.740 45.300 26.80 1.150 0.91 0 NA 0.09 2.78

Biotechnology & Drugs ZONA Zonagen, Incorporated NASD Healthcare 15.230 NA NA 3.05 2.30 NA 4.990 4.700 18.73 0.040 5.87 2 NA 0.00 16.00





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BioTech Industry 31Mar05





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs ZMTX ZymeTx, Inc. OTC Healthcare 0.340 NA NA 0.04 NA NA 8.610 6.600 0.00 -0.130 23.31 0 NA NA 0.20

Biotechnology & Drugs ZGEN ZymoGenetics, Inc. NASD Healthcare 880.560 NA NA 15.26 3.15 NA 57.700 23.800 27.20 -0.200 58.76 -6 NA 0.00 9.01

Major Drugs ABT Abbott Laboratories NYSE Healthcare 72,605.630 1.81 10.36 46.62 5.08 23.05 1,557.390 1,454.200 62.33 76.600 6.63 0 2.36 0.47 1.57

Major Drugs ACL Alcon, Inc. NYSE Healthcare 27,349.790 1.69 16.83 89.29 12.47 31.83 306.300 73.500 21.51 6.010 75.99 0 0.63 0.45 1.41

Major Drugs APNS Applied Neurosolutions, Inc. OTC Healthcare 21.750 NA NA 0.24 14.25 NA 90.640 83.100 6.83 0.000 8.32 -1 NA 0.01 10.43

Major Drugs AZN AstraZeneca PLC (ADR) NYSE Healthcare 65,026.850 1.26 13.09 39.53 4.51 17.34 1,645.000 1,628.600 7.90 -16.870 1.00 0 3.26 0.09 1.86

Major Drugs BAY Bayer AG (ADR) NYSE Healthcare 24,167.010 1.21 11.80 33.09 1.52 30.84 730.340 723.000 3.67 2.450 1.01 0 2.21 0.79 1.98

Major Drugs BMY Bristol Myers Squibb Co. NYSE Healthcare 49,751.130 4.69 3.89 25.46 4.86 21.11 1,954.090 1,940.200 66.58 78.030 0.71 0 4.40 1.01 1.50

Major Drugs LLY Eli Lilly & Co. NYSE Healthcare 59,014.750 1.56 11.41 52.10 5.40 31.37 1,132.720 977.900 68.71 27.690 13.67 -3 2.92 0.60 1.69

Major Drugs GSK GlaxoSmithKline plc (ADR) NYSE Healthcare 130,716.190 1.99 7.85 45.92 11.92 26.23 2,846.610 2,448.100 9.45 49.620 14.00 0 3.87 1.01 1.56

Major Drugs JNJ Johnson & Johnson NYSE Healthcare 199,711.440 1.74 11.37 67.16 6.27 23.69 2,973.670 2,943.900 64.39 135.280 1.00 -6 1.70 0.09 1.96

Major Drugs MRK Merck & Co., Inc. NYSE Healthcare 71,474.660 3.74 3.50 32.37 4.14 12.43 2,208.050 2,186.000 58.80 64.690 1.00 -3 4.70 0.40 1.15

Major Drugs NVD Novadel Pharma Inc AMEX Healthcare 41.280 NA NA 1.22 4.85 NA 33.830 22.200 8.45 0.980 34.39 3 NA 0.00 6.82

Major Drugs NVS Novartis AG (ADR) NYSE Healthcare 115,779.130 1.45 12.11 46.78 3.43 22.90 2,474.970 2,450.200 6.67 13.570 1.00 0 1.89 0.20 2.22

Major Drugs PFE Pfizer Inc. NYSE Healthcare 195,944.610 1.26 9.80 26.27 2.88 17.62 7,458.870 7,385.500 63.08 164.350 0.83 -1 2.89 0.27 1.50

Major Drugs PBH Prestige Brands Holdings, Inc. NYSE Healthcare 882.500 1.71 13.75 17.65 34.00 69.22 50.000 0.000 0.00 0.000 44.00 -11 NA 3.42 1.73

Major Drugs RHHBY Roche Holding Ltd. (ADR) OTC Healthcare 93,122.270 1.42 16.48 53.98 3.86 16.11 1,725.130 1,382.400 0.20 0.450 19.87 0 NA 0.32 2.97

Major Drugs SHR Schering AG (ADR) NYSE Healthcare 12,692.000 1.98 9.00 66.80 3.25 19.69 190.000 155.800 3.44 -2.690 18.00 0 1.99 0.08 2.49

Major Drugs SGP Schering-Plough Corp. NYSE Healthcare 28,044.520 4.29 19.60 18.15 4.38 NA 1,545.150 1,498.900 72.65 44.810 2.99 0 1.21 0.52 1.92

Major Drugs WYE Wyeth NYSE Healthcare 56,354.750 2.03 7.49 42.18 5.72 49.10 1,336.050 1,329.000 75.37 77.520 0.53 -2 2.18 0.83 1.69









492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 31Mar05 36 of 45 10/24/2011 3:30 PM

BioTech Industry 31Dec04





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs APPA A.P. Pharma, Inc. NASD Healthcare 41.140 NA NA 1.65 2.52 NA 24.930 23.400 41.47 0.590 4.04 0 NA 0.00 7.54

Biotechnology & Drugs AAII aaiPharma Inc. NASD Healthcare 92.900 -0.07 22.00 3.25 58.28 NA 28.590 20.200 33.59 -3.950 29.34 0 NA 203.07 0.59

Biotechnology & Drugs ASTM Aastrom Biosciences, Inc. NASD Healthcare 130.960 NA NA 1.42 7.24 NA 92.220 85.900 2.65 0.310 6.86 6 NA 0.00 21.42

Biotechnology & Drugs ABAX Abaxis, Inc. NASD Healthcare 285.830 2.10 30.00 14.49 4.87 12.83 19.730 18.900 54.07 0.180 4.19 -4 NA 0.00 5.58

Biotechnology & Drugs ABGX Abgenix, Inc. NASD Healthcare 921.010 NA NA 10.34 3.45 NA 89.070 71.700 81.18 3.710 19.50 -1 NA 0.79 6.79

Biotechnology & Drugs ABRX Able Laboratories Inc. NASD Healthcare 408.310 0.82 39.50 22.75 4.58 40.12 17.950 16.000 82.08 3.460 10.85 -15 NA 0.03 7.05

Biotechnology & Drugs ACAD ACADIA Pharmaceuticals Inc. NASD Healthcare 114.190 NA NA 6.77 3.06 NA 16.870 10.500 27.38 -0.250 37.75 0 NA 0.08 4.80

Biotechnology & Drugs ACAM Acambis plc (ADR) NASD Healthcare 485.600 NA NA 9.81 2.64 8.15 49.510 40.600 2.27 -0.130 17.99 0 NA 0.10 2.09

Biotechnology & Drugs ACCL Accelrys, Inc. NASD Healthcare 206.770 NA NA 7.80 1.89 NA 26.510 26.000 65.01 -0.130 1.92 0 NA 0.01 1.92

Biotechnology & Drugs AKC Access Pharmaceuticals AMEX Healthcare 54.940 NA NA 3.54 NA NA 15.520 13.300 32.00 0.170 14.31 6 NA NA 0.58

Biotechnology & Drugs AGNM Acrongenomics Inc. NASD Healthcare 42.220 NA NA 2.80 84.14 NA 15.080 7.500 NA NA 50.26 NA NA 0.00 0.14

Biotechnology & Drugs ACUS Acusphere, Inc. NASD Healthcare 109.130 NA NA 6.13 2.08 NA 17.800 16.200 40.87 2.660 9.00 0 NA 0.10 5.72

Biotechnology & Drugs ADZA Adeza Biomedical Corporation NASD Healthcare 278.230 NA NA 17.51 NA 27.49 15.890 3.800 NA NA 76.09 NA NA 0.00 3.97

Biotechnology & Drugs ADH Adherex Technologies Inc. AMEX Healthcare 64.600 NA NA 0.36 NA NA 179.460 151.700 0.00 0.000 15.47 0 NA NA NA

Biotechnology & Drugs ADLR Adolor Corporation NASD Healthcare 387.600 -0.54 15.00 9.92 2.88 NA 39.070 36.700 75.95 1.760 6.07 1 NA 0.00 11.26

Biotechnology & Drugs AVM Advanced Magnetics, Inc. AMEX Healthcare 125.640 NA NA 15.72 7.12 NA 7.990 7.000 35.38 0.030 12.41 0 NA 0.00 4.93

Biotechnology & Drugs APPI Advanced Plant Pharmaceuticals Inc. OTC Healthcare 2.470 NA NA 0.00 NA NA 705.380 355.200 0.00 -0.010 49.64 0 NA NA 0.02

Biotechnology & Drugs ATISZ Advanced Tissue Sciences OTC Healthcare 7.390 NA NA 0.10 0.51 NA 73.150 47.600 1.61 -0.120 34.93 0 NA 0.31 1.21

Biotechnology & Drugs ADVR Advanced Viral Research OTC Healthcare 98.900 NA NA 0.14 11.83 NA 696.490 640.800 0.02 0.030 8.00 0 NA 0.00 9.16

Biotechnology & Drugs AVNC Advancis Pharmaceutical Corporation NASD Healthcare 87.090 -0.08 30.00 3.82 1.91 NA 22.800 9.300 23.99 -0.190 59.21 -1 NA 0.06 3.39

Biotechnology & Drugs ANX ADVENTRX Pharmaceuticals, Inc. AMEX Healthcare 60.270 NA NA 1.12 4.12 NA 53.810 44.000 8.16 0.750 18.05 0 NA 0.00 21.61

Biotechnology & Drugs AOLS Aeolus Pharmaceuticals, Inc. OTC Healthcare 17.430 NA NA 1.25 3.15 NA 13.950 12.400 7.18 0.200 11.09 0 NA 0.14 4.96

Biotechnology & Drugs AEZS AEterna Zentaris Inc. (USA) NASD Healthcare 285.650 NA NA 6.26 2.82 NA 45.630 45.200 3.20 -1.250 0.94 0 NA 0.64 1.90

Biotechnology & Drugs AEMD Aethlon Medical, Inc. OTC Healthcare 6.730 NA NA 0.50 NA NA 13.450 9.600 NA NA 25.28 NA NA NA 0.01

Biotechnology & Drugs AFFX Affymetrix, Inc. NASD Healthcare 2,228.010 1.42 36.67 36.55 10.62 62.27 60.960 49.400 95.00 2.300 18.96 -28 NA 0.57 3.24

Biotechnology & Drugs AKN Akorn, Inc. AMEX Healthcare 79.250 NA NA 3.83 14.19 NA 20.690 6.700 4.56 0.020 67.62 -2 NA 0.23 1.87

Biotechnology & Drugs AMRI Albany Molecular Research NASD Healthcare 353.730 1.20 15.00 11.14 1.22 NA 31.750 13.900 63.99 -1.330 56.23 -1 NA 0.19 8.50

Biotechnology & Drugs ALXN Alexion Pharmaceuticals, Inc. NASD Healthcare 695.790 NA NA 25.20 4.54 NA 27.610 26.700 95.00 5.960 3.31 -18 NA 0.78 15.48

Biotechnology & Drugs ACEL Alfacell Corporation NASD Healthcare 154.360 NA NA 4.38 18.87 NA 35.240 30.900 4.55 0.700 12.32 3 NA 0.04 6.41

Biotechnology & Drugs ALKS Alkermes, Inc. NASD Healthcare 1,269.750 -1.01 25.00 14.09 47.54 NA 90.120 86.500 91.62 1.080 4.01 -6 NA 5.73 3.48

Biotechnology & Drugs AGN Allergan, Inc. NYSE Healthcare 10,643.450 1.51 19.52 81.07 10.67 62.65 131.290 128.700 89.39 0.110 1.97 0 0.44 0.59 2.91

Biotechnology & Drugs ALLP Alliance Pharmaceutical Corp. OTC Healthcare 6.070 NA NA 0.19 NA 0.84 31.920 29.700 10.60 -2.830 6.96 0 NA NA 0.55

Biotechnology & Drugs ALTH Allos Therapeutics, Inc. NASD Healthcare 74.770 NA NA 2.40 2.59 NA 31.150 23.100 24.32 -0.430 25.85 2 NA 0.00 9.92

Biotechnology & Drugs ALNY Alnylam Pharmaceuticals, Inc. NASD Healthcare 150.040 NA NA 7.47 3.35 NA 20.090 11.000 19.19 0.120 45.24 -2 NA 0.16 7.11

Biotechnology & Drugs ALO Alpharma Inc. NYSE Healthcare 893.020 1.36 18.83 16.95 0.80 100.30 52.690 40.200 75.45 -0.160 23.70 0 1.06 0.65 1.80

Biotechnology & Drugs AAA Altana Group (ADR) NYSE Healthcare 8,584.810 NA NA 63.00 4.22 17.13 136.270 68.100 1.58 -0.170 50.03 0 1.58 0.04 NA

Biotechnology & Drugs ALT Alteon Inc. AMEX Healthcare 63.500 NA NA 1.31 4.98 NA 48.470 45.100 20.38 -0.900 6.96 0 NA 0.00 6.64

Biotechnology & Drugs AMAR Amarillo Biosciences, Inc OTC Healthcare 4.370 NA NA 0.33 NA NA 13.240 7.800 0.10 0.010 41.06 0 NA NA 0.01

Biotechnology & Drugs AMRN Amarin Corporation plc (ADR) NASD Healthcare 85.060 NA NA 2.71 8.53 NA 31.390 21.300 0.04 -1.160 32.14 0 NA 0.00 2.05

Biotechnology & Drugs MABAA American Biogenetic Sciences, Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 44.950 34.500 0.00 0.000 23.25 0 NA NA 0.06

Biotechnology & Drugs AOBO American Oriental Bioengineering, Inc. OTC Healthcare 52.130 NA NA 1.55 2.10 8.96 33.630 11.200 0.00 0.000 66.70 0 NA 0.06 3.53

Biotechnology & Drugs APPX American Pharmaceutical Partners, Inc. NASD Healthcare 2,638.830 1.66 26.93 37.41 9.11 53.22 70.540 21.000 29.53 -1.230 70.23 5 NA 0.00 4.53

Biotechnology & Drugs ABC AmerisourceBergen Corp. NYSE Healthcare 6,597.890 1.13 13.33 58.68 1.48 14.45 112.440 110.500 95.00 2.530 1.73 0 0.17 0.33 1.36

Biotechnology & Drugs AMGN Amgen, Inc. NASD Healthcare 81,479.230 1.38 19.17 64.15 4.11 38.16 1,270.140 1,146.800 68.77 5.260 9.71 -15 NA 0.16 1.31

Biotechnology & Drugs AMLN Amylin Pharmaceuticals NASD Healthcare 2,204.150 NA NA 23.36 NA NA 94.360 80.700 81.00 5.610 14.47 -31 NA NA 8.49

Biotechnology & Drugs ANDS Anadys Pharmaceuticals, Inc. NASD Healthcare 166.910 NA NA 7.49 4.40 NA 22.290 17.200 27.31 -0.090 22.82 0 NA 0.08 7.35

Biotechnology & Drugs ADRX Andrx Corporation NASD Healthcare 1,590.750 1.27 16.66 21.83 2.35 26.59 72.870 71.000 93.58 15.050 2.57 0 NA 0.00 2.16

Biotechnology & Drugs ANPI Angiotech Pharmaceuticals, Inc.(USA) NASD Healthcare 1,543.050 2.38 20.00 18.41 3.87 NA 83.820 78.800 61.75 6.700 5.99 0 NA 0.00 16.97

Biotechnology & Drugs ANIK Anika Therapeutics, Inc. NASD Healthcare 92.450 NA NA 9.15 3.28 10.20 10.100 6.300 39.57 0.620 38.21 -15 NA 0.00 7.34

Biotechnology & Drugs ANXB Antex Biologics, Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 12.410 10.300 0.65 0.000 16.99 0 NA NA 0.79

Biotechnology & Drugs AGEN Antigenics, Inc. NASD Healthcare 460.680 NA NA 10.12 3.73 NA 45.520 43.100 33.64 -3.340 5.32 5 NA 0.09 5.62

Biotechnology & Drugs APHT Aphton Corporation NASD Healthcare 117.550 -0.10 40.00 3.11 4.01 NA 37.800 29.500 42.42 -0.880 21.95 0 NA 0.40 7.06

Biotechnology & Drugs ARNA Arena Pharmaceuticals NASD Healthcare 177.760 NA NA 6.70 1.26 NA 26.530 18.100 61.68 -0.930 31.78 -3 NA 0.00 17.69

Biotechnology & Drugs AGNT Argonaut Technologies NASD Healthcare 19.860 NA NA 0.96 0.53 NA 20.690 20.000 39.32 0.270 3.31 -3 NA 0.00 4.93

Biotechnology & Drugs ARIA Ariad Pharmaceuticals, Inc. NASD Healthcare 390.950 NA NA 7.43 5.04 NA 52.620 48.900 43.76 -2.020 7.06 -1 NA 0.09 8.60

Biotechnology & Drugs ARQL ArQule, Inc. NASD Healthcare 167.300 NA NA 5.79 2.01 NA 28.890 28.600 41.61 0.340 1.02 3 NA 0.03 3.54

Biotechnology & Drugs ARRY Array BioPharma Inc. NASD Healthcare 275.910 -0.27 50.00 9.52 5.45 NA 28.980 25.400 55.64 1.270 13.84 0 NA 0.00 2.06

Biotechnology & Drugs ASTR Astralis, Ltd. OTC Healthcare 53.290 NA NA 0.73 8.35 NA 73.000 20.400 1.18 -0.340 71.98 7 NA 0.00 10.23

Biotechnology & Drugs AGIX AtheroGenics, Inc. NASD Healthcare 879.770 NA NA 23.56 NA NA 37.340 31.800 95.00 2.750 14.84 0 NA NA 7.53

Biotechnology & Drugs AIMM AutoImmune Inc. OTC Healthcare 14.890 NA NA 0.88 1.47 NA 16.920 16.800 30.28 -0.050 0.71 0 NA 0.00 101.23

Biotechnology & Drugs AUXL Auxilium Pharmaceuticals, Inc. NASD Healthcare 182.380 -0.18 30.00 8.85 4.26 NA 20.610 8.900 74.41 15.340 56.81 12 NA 0.01 4.45

Biotechnology & Drugs AVN AVANIR Pharmaceuticals AMEX Healthcare 325.070 NA NA 3.41 31.87 NA 95.330 93.400 28.14 1.450 2.02 -2 NA 0.11 3.24

Biotechnology & Drugs AVAN AVANT Immunotherapeutics, Inc. NASD Healthcare 149.000 NA NA 2.01 3.55 NA 74.130 73.600 22.69 0.870 0.71 3 NA 0.01 9.61

Biotechnology & Drugs AVXT AVAX Technologies, Inc. OTC Healthcare 11.180 NA NA 0.31 5.64 NA 36.070 33.900 6.30 0.030 6.02 0 NA 0.17 1.17

Biotechnology & Drugs AVII AVI BioPharma, Inc. NASD Healthcare 84.890 NA NA 2.35 2.74 NA 36.120 25.600 11.14 -0.690 29.13 1 NA 0.00 17.65







492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 31Dec04 37 of 45 10/24/2011 3:30 PM

BioTech Industry 31Dec04





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs AVGN Avigen, Inc. NASD Healthcare 66.440 NA NA 3.26 0.78 NA 20.380 19.900 46.17 1.400 2.36 0 NA 0.09 43.97

Biotechnology & Drugs AXCA Axcan Pharma Inc. (USA) NASD Healthcare 880.260 1.02 20.00 19.32 2.25 19.75 45.560 38.300 45.24 -0.590 15.94 0 NA 0.33 2.71

Biotechnology & Drugs AXJ AXM Pharma, Inc. AMEX Healthcare 54.310 NA NA 3.38 6.29 NA 16.070 9.800 0.96 0.080 39.01 0 NA 0.00 3.96

Biotechnology & Drugs AXYX Axonyx Inc. NASD Healthcare 320.580 NA NA 6.20 3.54 NA 51.710 43.100 51.47 1.210 16.67 -10 NA 0.01 14.47

Biotechnology & Drugs BRL Barr Pharmaceuticals, Inc. NYSE Healthcare 4,667.710 1.26 15.26 45.54 4.46 35.58 102.500 97.400 75.39 3.100 4.97 -6 NA 0.04 4.18

Biotechnology & Drugs BTRX Barrier Therapeutics, Inc. NASD Healthcare 362.680 NA NA 16.60 3.76 NA 21.850 16.800 60.54 -0.080 23.11 1 NA 0.01 14.34

Biotechnology & Drugs BNT Bentley Pharmaceuticals, Inc. NYSE Healthcare 229.050 1.37 32.00 10.75 2.78 44.24 21.310 15.300 40.99 0.230 28.19 4 NA 0.03 2.74

Biotechnology & Drugs BASI Bioanalytical Systems, Inc. NASD Healthcare 24.350 NA NA 5.00 1.23 NA 4.870 3.000 6.65 0.010 38.40 0 NA 0.93 0.97

Biotechnology & Drugs BIOC Biocircuits Corporation OTC Healthcare 0.010 NA NA 0.00 NA NA 6.980 1.600 NA NA 77.09 NA NA 0.02 2.46

Biotechnology & Drugs BCRX BioCryst Pharmaceuticals, Inc. NASD Healthcare 125.340 NA NA 5.78 3.66 NA 21.680 16.200 36.90 -0.420 40.17 0 NA 0.00 7.20

Biotechnology & Drugs BDSI BioDelivery Sciences Int'l, Inc. NASD Healthcare 25.150 NA NA 3.52 12.09 NA 7.150 2.700 0.27 0.000 62.22 66 NA 0.11 1.59

Biotechnology & Drugs BIVN Bioenvision Inc. NASD Healthcare 256.230 NA NA 8.96 10.31 NA 28.600 28.500 44.94 0.970 0.34 -19 NA 0.00 6.37

Biotechnology & Drugs BIIB Biogen Idec Inc NASD Healthcare 22,540.340 2.24 20.42 66.61 3.31 NA 338.390 325.500 87.99 5.360 3.79 -65 NA 0.13 2.95

Biotechnology & Drugs BMRN BioMarin Pharmaceutical NASD Healthcare 412.140 NA NA 6.39 29.05 NA 64.500 63.500 74.02 3.000 1.55 0 NA 19.14 1.86

Biotechnology & Drugs BIOM Biomira Inc. (USA) NASD Healthcare 174.870 NA NA 2.41 8.82 NA 72.560 68.200 4.19 0.720 6.01 0 NA 0.00 9.89

Biotechnology & Drugs BNTK Bionet Technologies, Inc. OTC Healthcare 0.000 NA NA 0.00 0.00 NA 13.810 8.700 NA NA 37.02 NA NA 0.00 0.90

Biotechnology & Drugs BNRX Bionutrics, Inc. OTC Healthcare 4.570 NA NA 1.05 NA NA 4.350 2.100 0.00 0.000 51.76 0 NA NA 0.06

Biotechnology & Drugs BPRG BioProgress PLC (USA) NASD Healthcare 161.220 NA NA 14.25 3.21 NA 11.310 10.750 NA NA 4.99 NA NA 0.00 2.83

Biotechnology & Drugs BIOP BioPulse International OTC Healthcare 0.120 NA NA 0.01 NA NA 15.450 7.600 0.00 0.000 50.81 0 NA NA 0.04

Biotechnology & Drugs BPUR Biopure Corporation NASD Healthcare 41.270 NA NA 0.59 0.89 NA 69.950 63.900 8.37 -3.730 8.65 0 NA 0.00 3.18

Biotechnology & Drugs BPA BioSante Pharmaceuticals, Inc. AMEX Healthcare 101.140 NA NA 5.48 5.16 NA 18.460 11.600 12.77 1.080 21.23 29 NA 0.00 15.58

Biotechnology & Drugs BSTE Biosite Incorporated NASD Healthcare 996.840 1.44 18.29 61.54 5.01 29.93 16.200 14.800 95.00 -0.460 8.63 -14 NA 0.11 3.80

Biotechnology & Drugs BSLU Bio-Solutions International, Inc. OTC Healthcare 0.680 NA NA 3.50 NA NA 0.200 0.140 NA NA 28.06 NA NA NA NA

Biotechnology & Drugs BIOI BioSource International, Inc. NASD Healthcare 65.940 4.06 10.00 6.90 1.68 NA 9.560 7.800 33.92 -0.520 18.38 7 NA 0.00 3.30

Biotechnology & Drugs BSTC BioSpecifics Technologies Corp. OTC Healthcare 7.940 NA NA 1.49 4.12 NA 5.330 3.000 2.70 0.000 43.67 3 NA 1.03 0.65

Biotechnology & Drugs BIOHF Biotech Holdings Ltd. (USA) OTC Healthcare 44.100 NA NA 0.50 NA NA 88.210 43.200 0.00 0.000 51.03 0 NA NA 0.07

Biotechnology & Drugs BTX BioTime, Inc. AMEX Healthcare 26.900 NA NA 1.51 30.53 NA 17.810 17.100 1.47 -0.390 3.99 0 NA 0.00 12.23

Biotechnology & Drugs BTRNQ BioTransplant Inc. OTC Healthcare 0.050 NA NA 0.00 0.00 NA 25.390 19.600 0.64 0.000 22.79 0 NA 0.04 2.39

Biotechnology & Drugs BVF Biovail Corporation (USA) NYSE Healthcare 2,629.850 0.73 17.87 16.53 2.64 137.75 159.100 133.600 38.75 -1.900 16.03 0 NA 0.59 1.26

Biotechnology & Drugs BCII Bone Care International, Inc. NASD Healthcare 540.870 1.74 45.00 27.85 4.39 320.11 19.420 14.100 71.23 0.360 27.40 -5 NA 0.00 14.39

Biotechnology & Drugs BLSI Boston Life Sciences, Inc. NASD Healthcare 19.640 NA NA 0.57 NA NA 34.460 31.000 6.24 0.720 10.05 0 NA 1.59 1.28

Biotechnology & Drugs BDY Bradley Pharmaceuticals, Inc. NYSE Healthcare 307.240 0.87 17.65 19.40 1.90 15.92 15.840 13.200 92.00 -0.380 12.23 0 NA 0.67 3.27

Biotechnology & Drugs CADKF Cade Struktur Corporation OTC Healthcare 0.000 NA NA 0.00 2.06 3.45 8.340 7.700 NA NA 7.63 NA NA 0.00 1.50

Biotechnology & Drugs KDUS Cadus Corporation OTC Healthcare 20.110 NA NA 1.53 0.79 NA 13.140 7.600 1.64 0.160 42.18 0 NA 0.00 1,360.22

Biotechnology & Drugs KAL Callisto Pharmaceuticals, Inc. AMEX Healthcare 57.770 NA NA 1.98 10.32 NA 29.180 19.000 2.32 0.160 34.88 2 NA 0.00 6.96

Biotechnology & Drugs CBM Cambrex Corporation NYSE Healthcare 707.530 2.43 11.67 27.10 1.94 NA 26.110 25.200 89.58 0.400 3.48 -4 0.44 0.61 2.80

Biotechnology & Drugs CATG NASD

Cambridge Antibody Tech. Group plc (ADR) Healthcare 581.290 NA NA 14.14 3.69 NA 41.110 28.000 4.15 -0.070 31.89 0 NA 0.00 6.42

Biotechnology & Drugs OLED Cambridge Display Technology, Inc. NASD Healthcare 0.000 NA NA 0.00 0.00 NA 19.500 2.500 NA NA 87.18 NA NA 0.04 1.01

Biotechnology & Drugs CNVX CancerVax Corporation NASD Healthcare 290.400 NA NA 10.85 3.97 NA 26.760 16.600 26.18 -0.280 37.99 0 NA 0.04 6.37

Biotechnology & Drugs CPD A

Caraco Pharmaceutical Laboratories Ltd. MEX Healthcare 234.940 NA NA 9.55 NA 795.83 24.600 4.900 10.59 -0.120 80.08 -1 NA 0.42 1.32

Biotechnology & Drugs CAH Cardinal Health, Inc. NYSE Healthcare 25,125.230 1.15 14.42 58.15 3.06 17.77 432.080 427.000 80.40 -1.120 1.18 -1 0.21 0.40 1.38

Biotechnology & Drugs CRME Cardiome Pharma Corp.(USA) NASD Healthcare 303.840 NA NA 7.64 9.59 NA 39.770 36.600 21.53 8.560 7.97 0 NA 0.00 3.44

Biotechnology & Drugs CTE CardioTech International, Inc. AMEX Healthcare 52.170 NA NA 2.95 2.74 NA 17.680 17.200 8.96 -0.020 2.74 0 NA 0.00 5.39

Biotechnology & Drugs CARN Carrington Laboratories, Inc. NASD Healthcare 65.390 NA NA 6.13 5.00 NA 10.670 10.600 12.54 -0.190 0.63 -1 NA 0.32 1.31

Biotechnology & Drugs CRA Celera Genomics NYSE Healthcare 1,007.520 NA NA 13.75 1.11 NA 73.270 72.200 76.63 2.360 1.47 -5 NA 0.00 14.76

Biotechnology & Drugs CELG Celgene Corporation NASD Healthcare 4,365.980 1.84 44.35 26.52 9.82 99.70 164.630 148.200 91.92 14.360 9.98 -8 NA 0.90 10.63

Biotechnology & Drugs CEGE Cell Genesys, Inc. NASD Healthcare 364.260 NA NA 8.10 2.00 NA 44.970 44.800 54.61 0.630 0.38 0 NA 0.81 3.20

Biotechnology & Drugs CTIC Cell Therapeutics, Inc. NASD Healthcare 496.850 -0.10 25.00 8.14 NA NA 61.040 54.700 54.66 6.510 10.38 -6 NA NA 3.94

Biotechnology & Drugs CLGY Cellegy Pharmaceuticals, Inc. NASD Healthcare 74.630 NA NA 2.87 NA NA 26.010 20.600 13.34 0.260 20.81 -3 NA NA 4.75

Biotechnology & Drugs CVM CEL-SCI Corporation AMEX Healthcare 43.230 NA NA 0.60 6.90 NA 72.050 66.900 7.76 -0.170 7.15 -3 NA 0.00 19.41

Biotechnology & Drugs CEPH Cephalon, Inc. NASD Healthcare 2,919.540 0.86 25.00 50.88 4.03 NA 57.380 57.360 NA NA 0.04 -7 NA 1.79 6.13

Biotechnology & Drugs CERS Cerus Corporation NASD Healthcare 65.520 NA NA 2.95 2.43 NA 22.210 21.200 38.26 0.100 4.55 2 NA 2.23 1.36

Biotechnology & Drugs CHTL Chantal Pharmaceutical OTC Healthcare 0.040 NA NA 0.00 0.03 NA 40.810 31.400 0.00 0.000 23.06 0 NA 0.62 0.26

Biotechnology & Drugs CHTT Chattem Inc. NASD Healthcare 654.900 1.71 11.58 33.10 5.63 33.57 19.790 16.300 67.77 1.460 17.61 -33 NA 1.72 3.93

Biotechnology & Drugs CHIR Chiron Corporation NASD Healthcare 6,227.380 2.59 15.58 33.33 2.52 33.10 186.840 84.400 43.40 0.700 54.83 0 NA 0.45 3.33

Biotechnology & Drugs CNXS CNS, Inc. NASD Healthcare 177.620 1.42 13.67 12.73 2.84 27.86 13.950 11.300 46.56 0.220 19.01 5 1.57 0.00 5.25

Biotechnology & Drugs CLSCE Cobalis Corporation OTC Healthcare 27.100 NA NA 1.25 NA NA 21.680 4.100 0.00 0.000 80.82 -3 NA NA 0.01

Biotechnology & Drugs CGPI CollaGenex Pharmaceutical NASD Healthcare 105.590 2.53 11.00 7.34 2.74 27.39 14.390 12.300 61.43 -0.620 14.49 1 NA 0.00 6.20

Biotechnology & Drugs CBRX Columbia Laboratories NASD Healthcare 110.520 NA NA 2.65 NA NA 41.750 41.300 44.16 -1.290 1.08 0 NA NA 1.93

Biotechnology & Drugs CBTE Commonwealth Biotechnologies, Inc. NASD Healthcare 19.210 NA NA 6.00 2.95 85.71 3.200 2.200 5.28 0.020 31.29 1 NA 0.56 11.40

Biotechnology & Drugs COGE Compare Generiks, Inc. OTC Healthcare 0.000 NA NA 0.00 0.00 0.00 4.910 3.800 NA NA 22.69 NA NA 0.00 1.34

Biotechnology & Drugs CGEN Compugen Ltd. (USA) NASD Healthcare 138.270 NA NA 5.15 2.68 NA 26.850 23.600 31.16 1.090 12.10 0 NA 0.00 8.41

Biotechnology & Drugs CNCT Connetics Corporation NASD Healthcare 865.010 1.48 32.20 24.29 7.23 62.44 35.610 34.200 95.00 0.350 3.97 -23 NA 0.75 3.06

Biotechnology & Drugs VEGF Corautus Genetics Inc. NASD Healthcare 78.330 NA NA 5.38 5.26 NA 14.560 8.900 21.54 0.480 38.99 0 NA 0.69 19.20

Biotechnology & Drugs CORT Corcept Therapeutics Incorporated NASD Healthcare 141.790 -0.22 30.00 6.25 2.79 NA 22.690 8.600 24.64 0.380 62.11 -8 NA 0.00 30.34





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BioTech Industry 31Dec04





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs CONX Corgenix Medical Corporation OTC Healthcare 3.410 NA NA 0.55 4.08 NA 6.210 3.800 0.00 0.000 38.76 2 NA 1.12 1.31

Biotechnology & Drugs CGTK Corgentech, Inc. NASD Healthcare 230.120 NA NA 8.28 1.98 NA 27.790 13.900 55.11 1.710 49.99 -8 NA 0.01 6.77

Biotechnology & Drugs CRXA Corixa Corporation NASD Healthcare 216.080 NA NA 3.64 6.79 NA 59.360 51.400 51.87 0.460 13.41 0 NA 4.80 2.57

Biotechnology & Drugs COR Cortex Pharmaceuticals AMEX Healthcare 77.110 NA NA 2.71 4.06 NA 28.460 28.400 4.81 -1.080 0.19 1 NA 0.00 12.53

Biotechnology & Drugs CTRX Cotherix, Inc NASD Healthcare 234.130 NA NA 11.92 NA NA 19.640 5.000 0.00 0.000 74.54 8 NA 0.00 5.81

Biotechnology & Drugs CVGR Covalent Group, Inc. NASD Healthcare 33.980 NA NA 2.55 3.73 NA 13.320 12.300 20.98 0.120 7.69 0 NA 0.01 2.73

Biotechnology & Drugs CVD Covance Inc. NYSE Healthcare 2,419.550 1.37 18.71 38.75 3.97 27.44 62.440 60.600 83.90 -2.130 2.95 -7 NA 0.00 2.43

Biotechnology & Drugs CRTX Critical Therapeutics, Inc. NASD Healthcare 51.280 NA NA 8.00 2.56 NA 6.410 3.100 17.88 -1.120 75.04 0 NA 0.03 6.07

Biotechnology & Drugs CRXL Crucell N.V. (ADR) NASD Healthcare 497.670 NA NA 13.77 4.75 NA 36.140 31.800 12.81 -1.760 11.95 0 NA 0.02 5.90

Biotechnology & Drugs CBST Cubist Pharmaceuticals NASD Healthcare 477.220 -0.41 15.00 11.83 NA NA 40.340 39.900 75.04 1.610 1.73 -2 NA NA 0.90

Biotechnology & Drugs CRGN CuraGen Corporation NASD Healthcare 358.890 NA NA 7.16 2.77 NA 50.120 40.300 63.62 2.650 19.60 1 NA 1.85 22.58

Biotechnology & Drugs CRIS Curis, Inc. NASD Healthcare 246.850 NA NA 5.22 7.06 NA 41.560 39.600 28.50 1.950 3.57 -2 NA 0.20 6.00

Biotechnology & Drugs CVTX CV Therapeutics, Inc. NASD Healthcare 746.300 NA NA 23.00 8.01 NA 32.450 32.200 90.83 0.980 0.76 -1 NA 3.54 14.86

Biotechnology & Drugs CYAN Cyanotech Corporation NASD Healthcare 29.900 NA NA 1.44 2.03 37.90 20.760 16.700 11.60 -0.160 19.57 0 NA 0.15 3.71

Biotechnology & Drugs CYCC Cyclacel Group plc. (ADR) NASD Healthcare 0.000 NA NA 0.00 0.00 NA 15.240 0.000 NA NA 100.00 NA NA 0.04 7.93

Biotechnology & Drugs CYPB Cypress Bioscience, Inc. NASD Healthcare 420.610 NA NA 14.06 4.45 NA 29.920 26.600 73.01 1.120 11.08 -13 NA 0.00 22.88

Biotechnology & Drugs CYTO Cytogen Corporation NASD Healthcare 177.830 NA NA 11.52 3.88 NA 15.440 15.100 54.38 0.210 2.18 0 NA 0.05 5.74

Biotechnology & Drugs CYTK Cytokinetics, Inc. NASD Healthcare 290.410 -0.75 10.00 10.25 2.45 NA 28.330 5.800 38.15 0.320 59.07 -4 NA 0.08 10.53

Biotechnology & Drugs CYME Cytomedix, Inc. OTC Healthcare 48.440 NA NA 2.48 7.06 NA 19.530 14.800 1.45 0.000 24.23 -5 NA 0.00 3.80

Biotechnology & Drugs CYTR CytRx Corporation NASD Healthcare 55.250 NA NA 1.40 17.56 NA 39.460 32.800 4.47 0.220 16.88 0 NA 0.00 2.28

Biotechnology & Drugs DKHR D&K Healthcare Resources Inc NASD Healthcare 113.240 3.55 10.00 8.03 0.64 17.20 14.100 13.100 80.35 0.130 7.11 1 0.75 1.82 2.14

Biotechnology & Drugs DATA DATATRAK International, Inc. NASD Healthcare 66.810 NA NA 10.95 12.60 2,190.00 6.100 4.900 28.88 0.220 19.70 0 NA 0.00 3.09

Biotechnology & Drugs DCGN deCODE genetics, Inc. NASD Healthcare 425.740 NA NA 7.81 5.94 NA 54.510 46.200 39.27 0.700 15.25 -12 NA 2.90 5.96

Biotechnology & Drugs DGENQ Deltagen, Inc. OTC Healthcare 2.720 NA NA 0.07 0.20 NA 38.850 14.000 16.53 0.060 63.97 0 NA 0.37 0.23

Biotechnology & Drugs DNDN Dendreon Corporation NASD Healthcare 635.960 NA NA 10.78 2.92 NA 58.990 28.800 60.43 -3.530 51.18 0 NA 0.01 10.60

Biotechnology & Drugs DEPO DepoMed, Inc. NASD Healthcare 187.070 -0.22 30.00 5.40 94.82 NA 34.640 20.200 65.43 -0.070 41.69 2 NA 0.77 7.90

Biotechnology & Drugs DSCI Derma Sciences, Inc. OTC Healthcare 6.380 NA NA 0.67 0.90 NA 9.520 8.600 0.27 0.000 9.70 0 NA 0.73 1.43

Biotechnology & Drugs DIGE Digene Corporation NASD Healthcare 521.530 3.03 32.00 26.15 6.48 38.51 19.940 15.200 75.14 -1.260 23.79 -4 NA 0.01 2.97

Biotechnology & Drugs DSCO Discovery Laboratories NASD Healthcare 372.940 NA NA 7.93 13.50 NA 47.030 43.600 48.94 -1.880 7.29 0 NA 0.28 3.31

Biotechnology & Drugs DPII Discovery Partners Int'l NASD Healthcare 121.890 2.17 15.00 4.71 1.15 30.19 25.880 23.800 82.67 -0.330 8.03 0 NA 0.00 14.32

Biotechnology & Drugs DVSA Diversa Corporation NASD Healthcare 381.790 -0.23 50.00 8.74 2.44 NA 43.680 25.900 46.56 -0.060 40.71 0 NA 0.13 5.52

Biotechnology & Drugs DOCP DocPlanet.com Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 7.600 4.100 0.03 0.000 46.02 0 NA NA 0.38

Biotechnology & Drugs DOR DOR BioPharma, Inc. AMEX Healthcare 26.910 NA NA 0.64 6.08 NA 42.040 41.100 3.17 -1.300 2.24 0 NA 0.03 4.04

Biotechnology & Drugs DOVP DOV Pharmaceutical, Inc. NASD Healthcare 386.920 NA NA 18.05 11.86 NA 21.440 10.800 78.16 2.110 49.62 -20 NA 0.12 3.19

Biotechnology & Drugs RDY Dr Reddy's Laboratories Limited (ADR) NYSE Healthcare 1,517.370 NA NA 19.83 NA 36.79 76.520 56.600 14.48 -0.770 26.03 0 0.55 NA NA

Biotechnology & Drugs DRUG Dragon Pharmaceuticals Inc. (USA) OTC Healthcare 25.130 NA NA 1.22 2.82 NA 20.600 16.900 1.57 -0.080 17.97 0 NA 0.00 4.24

Biotechnology & Drugs DRAX DRAXIS Health Inc. (USA) NASD Healthcare 203.160 NA NA 4.96 3.17 27.87 40.960 33.600 40.06 1.510 17.97 0 NA 0.08 2.67

Biotechnology & Drugs DRRX DURECT Corporation NASD Healthcare 169.910 NA NA 3.28 6.71 NA 51.800 30.800 56.94 -2.900 40.54 3 NA 2.46 8.84

Biotechnology & Drugs DUSA DUSA Pharmaceuticals, Inc NASD Healthcare 241.240 -0.60 30.00 14.30 4.23 NA 16.870 15.000 55.79 -0.420 11.09 3 NA 0.00 18.54

Biotechnology & Drugs DYAX Dyax Corp. NASD Healthcare 227.630 NA NA 7.22 3.97 NA 31.530 23.400 66.30 0.790 25.78 -1 NA 0.22 5.02

Biotechnology & Drugs DVAX Dynavax Technologies Corp NASD Healthcare 196.990 NA NA 8.00 3.07 NA 24.620 19.200 27.39 0.040 22.02 -6 NA 0.00 8.80

Biotechnology & Drugs EPEI EAPI Entertainment, Inc. OTC Healthcare 1.770 NA NA 0.13 NA NA 13.590 11.400 NA NA 16.11 NA NA NA 0.02

Biotechnology & Drugs EW Edwards Lifesciences Corp NYSE Healthcare 2,452.670 1.90 13.02 41.26 4.11 NA 59.440 59.400 92.38 -0.020 0.07 -3 NA 0.45 1.92

Biotechnology & Drugs ESALY Eisai Co., Ltd (ADR) OTC Healthcare 9,539.450 NA NA 33.15 2.25 NA 287.770 218.700 0.28 0.020 24.00 0 NA 0.00 2.54

Biotechnology & Drugs ELN Elan Corporation, plc (ADR) NYSE Healthcare 10,592.570 -1.81 15.00 27.25 34.76 NA 388.720 380.900 56.57 2.150 2.01 0 NA 4.95 3.06

Biotechnology & Drugs ELI Elite Pharmaceuticals, Inc. AMEX Healthcare 44.520 NA NA 3.67 26.82 NA 12.130 11.300 0.39 0.020 6.85 -29 NA 1.64 0.39

Biotechnology & Drugs EMBX Embrex, Inc. NASD Healthcare 104.810 NA NA 13.26 2.29 44.35 7.900 7.000 39.52 -0.060 11.44 -2 NA 0.20 2.90

Biotechnology & Drugs EMIS Emisphere Technologies NASD Healthcare 74.270 NA NA 4.02 NA NA 18.470 18.200 30.93 -1.940 1.49 -1 NA NA 5.36

Biotechnology & Drugs ENCY Encysive Pharmaceuticals, Inc. NASD Healthcare 572.840 NA NA 9.93 7.67 NA 57.690 56.500 69.12 9.710 2.06 0 NA 0.02 6.05

Biotechnology & Drugs ENDP Endo Pharmaceuticals NASD Healthcare 2,770.150 1.26 14.50 21.01 4.30 33.89 131.850 30.300 51.09 11.360 63.97 -31 NA 0.00 2.22

Biotechnology & Drugs EVSC Endovasc, Inc. OTC Healthcare 7.260 NA NA 0.08 NA NA 96.860 90.600 0.01 0.000 6.46 -5 NA NA 0.33

Biotechnology & Drugs ENMD EntreMed, Inc. NASD Healthcare 120.450 NA NA 3.24 6.36 NA 37.180 17.700 16.33 -0.820 52.39 3 NA 0.00 11.72

Biotechnology & Drugs ETOP Entropin, Inc. OTC Healthcare 4.290 NA NA 0.14 NA NA 30.650 26.000 0.00 0.000 15.16 0 NA 0.00 21.58

Biotechnology & Drugs ENZN Enzon Pharmaceuticals, Inc. NASD Healthcare 600.850 2.45 34.33 13.72 2.07 NA 43.790 43.700 79.67 3.940 0.21 0 NA 1.38 6.44

Biotechnology & Drugs ELAB Eon Labs, Inc. NASD Healthcare 2,398.220 1.01 22.50 27.00 5.81 22.59 88.820 28.400 31.04 -0.890 68.03 -2 NA 0.00 3.13

Biotechnology & Drugs EPMN Epimmune Inc. NASD Healthcare 26.570 NA NA 1.66 2.10 NA 16.000 10.100 10.57 0.050 36.89 0 NA 0.00 4.55

Biotechnology & Drugs EPIX EPIX Pharmaceuticals, Inc. NASD Healthcare 413.530 NA NA 17.91 9.08 NA 23.090 14.100 90.90 0.710 38.94 -84 NA 2.53 5.67

Biotechnology & Drugs ERGO Ergo Science Corporation OTC Healthcare 14.190 NA NA 2.44 0.65 2.95 5.810 5.500 1.93 0.000 5.40 0 NA 0.00 126.75

Biotechnology & Drugs EXAS EXACT Sciences Corp. NASD Healthcare 100.320 NA NA 3.83 2.36 NA 26.190 19.500 66.86 -0.520 25.55 0 NA 0.00 8.48

Biotechnology & Drugs EXEG eXegenics Inc. OTC Healthcare 5.520 NA NA 0.34 0.61 NA 16.230 15.800 6.98 0.000 2.64 0 NA 0.00 35.57

Biotechnology & Drugs EXEL Exelixis, Inc. NASD Healthcare 710.710 NA NA 9.50 8.81 NA 74.810 63.000 82.79 3.400 15.79 -29 NA 1.39 3.38

Biotechnology & Drugs EYET Eyetech Pharmaceuticals, Inc. NASD Healthcare 1,890.700 NA NA 45.50 12.07 NA 41.550 27.400 70.25 7.030 34.06 -14 NA 0.01 8.84

Biotechnology & Drugs FHRX First Horizon Pharmaceutical Corp. NASD Healthcare 810.080 1.20 27.50 22.89 2.58 30.12 35.390 26.100 94.56 3.630 26.25 -4 NA 0.48 9.71

Biotechnology & Drugs FLML Flamel Technologies S.A. (ADR) NASD Healthcare 417.990 0.91 50.00 19.49 4.51 221.48 21.450 21.000 36.89 0.120 2.08 0 NA 0.02 5.85

Biotechnology & Drugs FMTI Forbes Medi-Tech Inc. (USA) NASD Healthcare 91.510 NA NA 2.71 3.20 NA 33.770 32.400 13.71 -0.320 4.03 0 NA 0.07 5.09





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BioTech Industry 31Dec04





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs FRX Forest Laboratories, Inc. NYSE Healthcare 16,526.740 0.96 18.54 44.86 4.47 18.88 368.410 361.200 88.11 -0.850 1.96 -12 NA 0.00 5.36

Biotechnology & Drugs GGEN GalaGen Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 12.280 7.500 0.08 0.000 38.90 0 NA NA 0.37

Biotechnology & Drugs GENR Genaera Corporation NASD Healthcare 194.460 -0.66 15.00 3.42 8.99 NA 56.860 42.600 20.99 1.430 25.08 3 NA 0.00 8.39

Biotechnology & Drugs GNSC Genaissance Pharm. Inc. NASD Healthcare 65.650 NA NA 2.13 3.80 NA 30.820 20.100 30.91 0.030 34.79 0 NA 0.30 1.30

Biotechnology & Drugs GLGC Gene Logic Inc. NASD Healthcare 116.490 NA NA 3.68 0.66 NA 31.650 31.100 46.97 -1.310 1.75 14 NA 0.01 5.81

Biotechnology & Drugs GNLB Genelabs Technologies NASD Healthcare 105.980 NA NA 1.20 7.44 NA 88.320 70.400 42.91 1.010 20.29 0 NA 0.03 3.64

Biotechnology & Drugs GMXX GeneMax Corporation OTC Healthcare 7.240 NA NA 0.36 NA NA 20.100 15.900 0.07 0.000 20.91 0 NA NA 0.02

Biotechnology & Drugs GCOR Genencor International Inc. NASD Healthcare 978.450 NA NA 16.40 2.70 36.77 59.660 8.200 13.09 0.260 86.26 0 NA 0.12 3.57

Biotechnology & Drugs DNA Genentech, Inc. NYSE Healthcare 57,141.410 2.43 26.83 54.44 8.20 83.37 1,049.620 431.200 42.80 10.640 58.92 -18 NA 0.06 3.12

Biotechnology & Drugs GNBT Generex Biotechnology NASD Healthcare 26.070 NA NA 0.75 52.02 NA 34.750 29.600 0.64 -0.070 14.83 0 NA 0.15 1.82

Biotechnology & Drugs GBI Genesis Bioventures, Inc. AMEX Healthcare 7.140 NA NA 0.23 1.70 NA 31.060 16.500 0.17 0.000 46.88 0 NA 0.54 0.02

Biotechnology & Drugs GTOP Genitope Corporation NASD Healthcare 407.740 -0.84 15.00 17.04 6.23 NA 23.930 20.200 26.34 0.590 15.58 -19 NA 0.00 24.22

Biotechnology & Drugs GNTA Genta Incorporated NASD Healthcare 141.430 NA NA 1.76 NA NA 80.360 46.200 31.35 -2.770 42.51 1 NA NA 1.02

Biotechnology & Drugs GNVC GenVec, Inc. NASD Healthcare 90.570 NA NA 1.63 2.66 NA 55.560 36.600 27.34 0.240 34.13 1 NA 0.14 3.31

Biotechnology & Drugs GENZ Genzyme Corporation NASD Healthcare 13,325.290 1.86 17.74 58.07 4.02 41.42 229.470 204.900 91.30 9.040 10.71 -16 NA 0.29 2.56

Biotechnology & Drugs GORX GeoPharma, Inc. NASD Healthcare 37.060 NA NA 4.67 2.19 467.00 7.940 3.300 21.28 0.460 58.42 -2 NA 0.24 5.07

Biotechnology & Drugs GERN Geron Corporation NASD Healthcare 363.700 NA NA 7.97 3.99 NA 45.630 43.500 23.07 0.090 4.67 -7 NA 0.04 12.46

Biotechnology & Drugs GILD Gilead Sciences, Inc. NASD Healthcare 15,147.740 1.83 20.44 34.99 10.84 30.01 432.920 424.600 90.19 7.970 1.92 -22 NA 0.25 7.85

Biotechnology & Drugs GLIAQ Gliatech Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 9.680 7.800 0.96 0.040 19.45 0 NA NA 0.90

Biotechnology & Drugs GLBM Global Marine, Ltd. OTC Healthcare 0.010 NA NA 0.04 0.00 NA 0.380 0.350 NA NA 6.88 NA NA 0.13 4.45

Biotechnology & Drugs GLGSD GlycoGenesys, Inc. NASD Healthcare 22.180 NA NA 2.20 6.38 NA 10.080 7.100 NA NA 29.59 NA NA 0.00 2.55

Biotechnology & Drugs GPCB GPC Biotech AG (ADR) NASD Healthcare 304.890 NA NA 14.21 2.29 NA 21.460 19.300 0.95 0.270 9.90 0 NA 0.02 12.80

Biotechnology & Drugs GTCB GTC Biotherapeutics, Inc. NASD Healthcare 58.970 NA NA 1.52 1.43 NA 38.790 33.200 21.44 1.500 14.42 0 NA 0.36 1.96

Biotechnology & Drugs GTXI GTx, Inc. NASD Healthcare 332.640 NA NA 13.49 4.71 NA 24.660 8.000 21.45 1.910 67.56 14 NA 0.00 19.58

Biotechnology & Drugs GLFD Guilford Pharmaceuticals NASD Healthcare 217.980 NA NA 4.95 3.51 NA 44.040 34.300 85.08 7.960 23.95 1 NA 2.15 5.94

Biotechnology & Drugs HTI Halozyme Therapeutics, Inc. AMEX Healthcare 104.790 NA NA 2.20 48.69 NA 47.630 47.200 0.00 0.000 0.90 5 NA 0.00 1.81

Biotechnology & Drugs HNAB Hana Biosciences Inc OTC Healthcare 63.700 NA NA 5.90 16.70 NA 10.800 3.700 NA NA 65.73 NA NA 0.37 3.04

Biotechnology & Drugs VGENQ Harvard Scientific Corp. OTC Healthcare 0.000 NA NA 0.00 NA NA 29.330 5.900 NA NA 79.88 NA NA NA NA

Biotechnology & Drugs HAUSQ Hauser, Inc. OTC Healthcare 0.070 NA NA 0.01 NA NA 6.440 2.500 0.00 0.000 61.16 0 NA NA 0.71

Biotechnology & Drugs HKRRF Hawker Resources Inc. (USA) OTC Healthcare 133.520 NA NA 3.10 1.33 22.79 43.070 35.700 0.32 -0.150 17.12 0 NA 0.43 0.56

Biotechnology & Drugs HESG Health Sciences Group, Inc. OTC Healthcare 11.410 NA NA 0.70 NA NA 16.300 8.400 NA NA 48.45 NA NA NA 0.39

Biotechnology & Drugs HCTL Healthcare Technologies NASD Healthcare 4.900 NA NA 0.64 NA 6.60 7.650 2.500 0.21 0.000 67.32 0 NA NA NA

Biotechnology & Drugs HXBM Helix BioMedix, Inc. OTC Healthcare 23.690 NA NA 1.75 6.95 NA 13.540 11.500 0.00 0.000 15.07 0 NA 0.00 24.26

Biotechnology & Drugs HEMA HemaCare Corporation OTC Healthcare 12.380 NA NA 1.55 2.58 8.47 7.990 7.400 0.95 0.000 7.34 1 NA 0.22 1.77

Biotechnology & Drugs HMGN Hemagen Diagnostics, Inc. OTC Healthcare 4.050 NA NA 0.40 16.79 NA 10.110 8.200 0.43 0.040 18.93 3 NA 17.96 0.91

Biotechnology & Drugs HEB Hemispherx BioPharma, Inc AMEX Healthcare 93.960 NA NA 1.90 4.14 NA 49.450 44.500 6.20 1.380 10.01 0 NA 0.13 5.85

Biotechnology & Drugs HMSL Hemosol Corp. (USA) NASD Healthcare 46.970 NA NA 0.82 0.78 NA 57.150 48.000 7.79 1.030 16.00 0 NA 0.28 0.51

Biotechnology & Drugs HSKA Heska Corporation NASD Healthcare 57.480 NA NA 1.17 21.36 NA 49.170 14.000 43.89 0.960 71.53 -1 NA 4.20 1.14

Biotechnology & Drugs HITK Hi-Tech Pharmacal Co. NASD Healthcare 143.680 0.98 27.00 18.44 2.18 25.47 7.790 4.900 34.28 -0.330 37.12 -2 NA 0.00 6.86

Biotechnology & Drugs HEPH Hollis-Eden Pharmaceuticals Inc. NASD Healthcare 181.670 -0.10 75.00 9.42 2.73 NA 19.290 17.300 33.45 0.160 10.29 0 NA 0.00 21.58

Biotechnology & Drugs HSP Hospira, Inc. NYSE Healthcare 5,229.180 2.64 7.20 33.50 5.79 16.84 156.090 146.700 61.88 4.650 6.02 1 NA 0.77 2.17

Biotechnology & Drugs HGSI Human Genome Sciences NASD Healthcare 1,566.700 NA NA 12.02 2.17 NA 130.340 127.000 82.61 8.250 2.56 -1 NA 0.70 16.75

Biotechnology & Drugs HBY Hybridon, Inc. AMEX Healthcare 53.230 NA NA 0.48 3.39 NA 110.900 84.300 7.68 0.010 23.99 5 NA 0.00 8.01

Biotechnology & Drugs ICLR ICON plc (ADR) NASD Healthcare 531.410 1.00 19.00 38.39 2.39 19.70 13.840 13.600 68.57 0.340 1.76 0 NA 0.03 1.97

Biotechnology & Drugs ICOR Icoria, Inc. NASD Healthcare 23.610 NA NA 0.65 1.68 NA 36.320 32.500 25.46 -0.320 10.53 3 NA 0.31 0.79

Biotechnology & Drugs ICOS ICOS Corporation NASD Healthcare 1,796.660 NA NA 28.28 45.76 NA 63.530 58.000 72.38 1.310 8.71 -1 NA 7.10 8.13

Biotechnology & Drugs IDBE ID Biomedical Corporation (USA) NASD Healthcare 629.960 NA NA 14.95 3.29 NA 42.140 39.600 12.83 0.710 6.02 0 NA 0.23 1.39

Biotechnology & Drugs IDIX Idenix Pharmaceuticals, Inc. NASD Healthcare 822.400 -2.72 44.00 17.15 6.70 NA 47.950 5.800 14.86 7.130 87.90 10 NA 0.03 5.95

Biotechnology & Drugs IDXX IDEXX Laboratories, Inc. NASD Healthcare 1,837.010 1.82 14.33 54.59 4.50 26.77 33.650 33.600 90.29 -1.030 0.15 -4 NA 0.00 3.84

Biotechnology & Drugs IG IGI, Inc. AMEX Healthcare 14.480 NA NA 1.25 3.78 NA 11.580 8.400 4.09 0.000 28.34 0 NA 0.00 2.50

Biotechnology & Drugs ILXO ILEX Oncology, Inc. NASD Healthcare 984.270 NA NA 25.05 5.74 NA 39.290 38.700 77.42 -1.650 1.51 -19 NA 0.12 4.23

Biotechnology & Drugs IMCL ImClone Systems Incorporated NASD Healthcare 3,812.820 1.20 20.56 46.08 20.30 40.28 82.740 59.900 68.50 1.990 27.61 -21 NA 3.20 5.41

Biotechnology & Drugs ICPH IMCOR Pharmaceutical Co. OTC Healthcare 40.830 NA NA 0.51 3.38 NA 80.070 42.400 5.23 2.880 47.04 0 NA 0.10 0.32

Biotechnology & Drugs IME IMI International Medical Innov. (USA) AMEX Healthcare 52.960 NA NA 2.49 15.35 NA 21.270 18.700 5.13 0.270 12.08 0 NA 0.00 20.36

Biotechnology & Drugs IMM Immtech International, Inc. AMEX Healthcare 130.960 NA NA 11.99 22.57 NA 10.920 8.300 8.71 0.230 24.01 -1 NA 0.00 8.36

Biotechnology & Drugs ICCC ImmuCell Corporation NASD Healthcare 19.750 NA NA 7.16 2.63 NA 2.760 2.200 2.39 0.010 20.23 0 NA 0.00 24.60

Biotechnology & Drugs IMMFF Immune Network Ltd. OTC Healthcare 0.130 NA NA 0.01 NA NA 20.920 12.800 0.03 0.000 38.81 0 NA NA 0.05

Biotechnology & Drugs IMGN ImmunoGen, Inc. NASD Healthcare 360.590 -1.44 15.00 8.84 3.81 NA 40.790 37.100 41.13 -0.020 9.05 0 NA 0.00 10.42

Biotechnology & Drugs IMMU Immunomedics, Inc. NASD Healthcare 164.380 NA NA 3.04 7.67 NA 54.070 43.400 31.73 -0.790 19.74 0 NA 0.69 4.61

Biotechnology & Drugs IPXL Impax Laboratories Inc. NASD Healthcare 928.740 2.72 25.30 15.88 10.76 1,985.00 58.480 40.000 67.36 5.780 31.61 6 NA 1.25 4.44

Biotechnology & Drugs INCY Incyte Corporation NASD Healthcare 737.850 NA NA 9.99 23.99 NA 73.860 55.400 85.17 0.740 24.99 7 NA 12.32 6.91

Biotechnology & Drugs IDEV Indevus Pharmaceuticals NASD Healthcare 279.860 NA NA 5.96 NA NA 46.960 46.500 40.07 1.480 0.97 -7 NA NA 4.92

Biotechnology & Drugs INHX Inhibitex, Inc. NASD Healthcare 147.250 NA NA 8.04 3.61 NA 18.310 5.000 20.31 -0.180 72.70 16 NA 0.06 9.28

Biotechnology & Drugs INKP InKine Pharmaceutical Company, Inc. NASD Healthcare 264.800 NA NA 5.43 19.84 96.96 48.770 46.400 39.91 0.480 4.85 -4 NA 0.00 4.90

Biotechnology & Drugs ISV Insite Vision Inc. AMEX Healthcare 54.890 NA NA 0.88 8.27 NA 62.370 53.000 10.48 3.930 15.03 0 NA 0.05 5.64





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Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs INSM Insmed Incorporated NASD Healthcare 84.460 NA NA 2.20 17.21 NA 38.410 35.800 17.70 -0.060 6.80 2 NA 0.00 1.37

Biotechnology & Drugs ISPH Inspire Pharmaceuticals, Inc. NASD Healthcare 695.760 NA NA 16.77 5.60 NA 41.490 40.800 77.93 7.340 1.66 -11 NA 0.02 13.06

Biotechnology & Drugs INB Integrated BioPharma, Inc. AMEX Healthcare 86.430 NA NA 6.90 4.00 NA 12.530 6.000 2.65 -0.010 52.10 0 NA 0.21 2.40

Biotechnology & Drugs IFSC Interferon Sciences, Inc. OTC Healthcare 1.120 NA NA 0.03 0.62 1.07 37.340 19.800 0.12 0.000 46.97 0 NA 0.12 3.13

Biotechnology & Drugs ITMN InterMune, Inc. NASD Healthcare 424.990 NA NA 13.26 8.05 NA 32.050 28.200 95.00 2.370 12.01 4 NA 3.23 6.31

Biotechnology & Drugs INIS International Isotopes Inc. OTC Healthcare 15.910 NA NA 0.10 18.60 NA 159.070 101.300 NA NA 36.32 NA NA 1.43 6.39

Biotechnology & Drugs IPA Interpharm Holdings, Inc. AMEX Healthcare 61.170 NA NA 2.45 2.68 54.44 24.970 18.700 3.71 0.030 25.10 1 NA 0.32 3.46

Biotechnology & Drugs IBCL Int'l BioChemical Industries, Inc. OTC Healthcare 0.010 NA NA 0.00 NA NA 94.160 92.500 0.01 0.000 1.77 0 NA NA 0.02

Biotechnology & Drugs IBPI IntraBiotics Pharmaceuticals NASD Healthcare 36.170 -0.11 15.00 4.08 0.72 NA 8.870 6.500 61.20 1.150 26.69 0 NA 0.00 27.15

Biotechnology & Drugs INGN Introgen Therapeutics, Inc NASD Healthcare 229.220 NA NA 8.44 18.91 NA 27.160 16.700 14.95 -1.850 38.51 -2 NA 0.67 2.67

Biotechnology & Drugs IMA Inverness Medical Innovations, Inc. AMEX Healthcare 510.540 -1.86 25.00 25.10 1.88 NA 20.340 8.900 44.42 -0.200 56.24 3 NA 0.74 1.81

Biotechnology & Drugs IVRO InVitro International OTC Healthcare 0.220 NA NA 0.02 0.53 15.00 14.510 9.000 0.00 0.000 37.96 0 NA 0.00 9.37

Biotechnology & Drugs IVGN Invitrogen Corporation NASD Healthcare 3,439.090 1.48 15.63 67.13 1.86 51.13 51.230 50.200 95.00 -0.180 2.01 9 NA 0.71 7.04

Biotechnology & Drugs IOX IOMED, Inc. AMEX Healthcare 17.780 NA NA 2.70 6.16 17.88 6.590 4.600 7.41 0.220 30.14 -4 NA 0.19 6.10

Biotechnology & Drugs ISIS ISIS Pharmaceuticals, Inc. NASD Healthcare 337.940 NA NA 5.90 NA NA 57.280 51.000 56.35 -0.470 10.96 -24 NA NA 3.72

Biotechnology & Drugs ILE Isolagen, Inc. AMEX Healthcare 237.480 NA NA 7.87 4.40 NA 30.170 27.400 42.82 0.180 9.20 -2 NA 0.01 8.10

Biotechnology & Drugs ISTA ISTA Pharmaceuticals NASD Healthcare 176.730 NA NA 10.12 7.87 NA 17.460 7.000 87.18 2.960 46.13 -30 NA 0.00 3.10

Biotechnology & Drugs ITER IT&E International Group OTC Healthcare 9.120 NA NA 0.48 15.25 NA 19.000 18.800 NA NA 1.05 NA NA 2.49 1.18

Biotechnology & Drugs IVX IVAX Corporation AMEX Healthcare 3,966.560 0.87 25.40 15.82 3.39 24.41 250.730 195.600 62.89 17.680 21.99 4 NA 0.91 2.41

Biotechnology & Drugs KNDL Kendle International Inc. NASD Healthcare 116.460 NA NA 8.80 1.18 58.67 13.230 11.000 62.60 0.110 16.88 0 NA 0.11 1.88

Biotechnology & Drugs KERX Keryx Biopharmaceuticals NASD Healthcare 360.220 NA NA 11.57 7.77 NA 31.130 21.300 54.38 0.700 31.59 -6 NA 0.00 20.14

Biotechnology & Drugs KG King Pharmaceuticals NYSE Healthcare 2,996.410 1.93 10.74 12.40 1.58 953.85 241.650 239.800 75.80 -2.700 0.76 0 NA 0.18 1.56

Biotechnology & Drugs KOSP KOS Pharmaceuticals, Inc. NASD Healthcare 1,499.310 0.67 20.00 37.64 3.89 15.48 39.830 19.100 36.24 -0.870 52.05 -15 NA 0.08 2.25

Biotechnology & Drugs KOSN Kosan Biosciences Incorporated NASD Healthcare 201.030 NA NA 6.93 2.65 NA 29.010 21.200 63.54 -1.220 26.92 0 NA 0.06 4.81

Biotechnology & Drugs KV.A K-V Pharmaceutical Company NYSE Healthcare 1,085.280 1.29 17.70 22.05 3.89 24.75 49.220 35.200 56.40 0.680 28.48 0 NA 0.78 10.62

Biotechnology & Drugs LJPC La Jolla Pharmaceutical Company NASD Healthcare 102.540 NA NA 1.67 2.79 NA 61.400 59.800 59.29 3.950 2.61 0 NA 0.05 4.72

Biotechnology & Drugs LCI Lannett Company, Inc. AMEX Healthcare 237.270 NA NA 9.85 2.29 18.98 24.090 9.800 4.54 -0.090 59.32 -2 NA 0.11 5.10

Biotechnology & Drugs LSBC Large Scale Biology Corp. NASD Healthcare 39.500 NA NA 1.26 2.82 NA 31.350 25.100 8.28 0.130 19.93 -3 NA 0.02 3.15

Biotechnology & Drugs LCAR Lescarden Inc. OTC Healthcare 12.230 NA NA 0.41 NA NA 29.830 20.100 1.41 0.080 32.62 0 NA NA 0.25

Biotechnology & Drugs LEXG Lexicon Genetics Incorporated NASD Healthcare 491.910 -0.62 15.00 7.76 4.03 NA 63.430 49.900 53.91 1.210 21.33 2 NA 0.31 3.23

Biotechnology & Drugs LIFC LifeCell Corporation NASD Healthcare 291.180 0.97 81.00 10.22 5.05 15.58 28.490 28.200 56.48 0.040 1.02 0 NA 0.00 5.46

Biotechnology & Drugs LCBM Lifecore Biomedical, Inc. NASD Healthcare 145.750 0.52 45.00 11.26 2.90 51.65 12.940 12.300 41.39 0.040 4.98 0 NA 0.11 5.86

Biotechnology & Drugs LGND Ligand Pharmaceuticals NASD Healthcare 860.570 12.41 36.50 11.64 20.99 NA 73.930 53.200 93.71 -6.440 28.04 0 NA 4.25 1.75

Biotechnology & Drugs LIPD Lipid Sciences, Inc. NASD Healthcare 90.420 NA NA 3.66 5.16 NA 24.700 14.700 4.84 0.020 40.50 -3 NA 0.00 8.17

Biotechnology & Drugs LRP Lorus Therapeutics Inc. (USA) AMEX Healthcare 103.080 NA NA 0.60 5.52 NA 171.800 170.100 1.04 0.310 0.99 0 NA 0.00 4.02

Biotechnology & Drugs LMNX Luminex Corporation NASD Healthcare 276.530 NA NA 8.88 6.03 NA 31.140 28.300 36.02 -1.080 9.12 2 NA 0.00 8.16

Biotechnology & Drugs LYNX Lynx Therapeutics, Inc. NASD Healthcare 28.760 NA NA 3.82 6.62 NA 7.530 6.300 19.54 -0.150 16.31 0 NA 0.05 1.24

Biotechnology & Drugs MCHM MacroChem Corporation NASD Healthcare 28.340 NA NA 0.73 3.54 NA 38.830 36.100 26.42 0.620 7.02 1 NA 0.00 9.00

Biotechnology & Drugs MHTT Manhattan Pharmaceuticals, Inc. OTC Healthcare 26.710 NA NA 0.97 4.30 NA 27.540 21.300 6.65 1.830 22.66 8 NA 0.00 5.04

Biotechnology & Drugs MTEX Mannatech, Inc. NASD Healthcare 504.140 NA NA 19.04 11.42 27.59 26.480 14.700 11.66 0.280 44.48 -17 0.74 0.00 1.50

Biotechnology & Drugs MNKD MannKind Corporation NASD Healthcare 516.690 NA NA 15.75 2.99 NA 32.810 6.300 12.60 4.130 80.80 4 NA 0.00 12.24

Biotechnology & Drugs MSHL Marshall Edwards, Inc. NASD Healthcare 509.310 NA NA 8.95 23.46 NA 56.940 6.800 0.61 -0.190 88.06 0 NA 0.00 11.22

Biotechnology & Drugs MATK Martek Biosciences Corp. NASD Healthcare 1,501.190 1.48 25.00 51.20 4.29 33.12 29.320 28.300 94.46 1.290 3.48 -5 NA 0.00 2.39

Biotechnology & Drugs MZT Matritech, Inc. AMEX Healthcare 45.140 NA NA 1.06 8.67 NA 42.590 41.900 7.75 -0.270 1.62 7 NA 0.36 2.32

Biotechnology & Drugs MTXX Matrixx Initiatives, Inc. NASD Healthcare 109.550 0.57 40.00 11.56 2.58 25.52 9.480 9.100 24.40 0.240 3.98 -1 NA 0.05 2.50

Biotechnology & Drugs MAXM Maxim Pharmaceuticals NASD Healthcare 86.250 NA NA 3.02 1.62 NA 28.560 27.800 33.41 -1.600 2.66 0 NA 0.02 4.84

Biotechnology & Drugs MAXY Maxygen, Inc. NASD Healthcare 452.180 NA NA 12.79 2.01 NA 35.350 24.700 32.41 -0.580 30.14 -9 NA 0.01 17.27

Biotechnology & Drugs MDZ MDS Inc. (USA) NYSE Healthcare 2,012.140 1.02 15.00 14.17 1.62 35.96 142.000 115.000 42.83 -10.940 19.01 0 0.92 0.33 1.91

Biotechnology & Drugs MEDX Medarex, Inc. NASD Healthcare 921.170 NA NA 10.78 5.78 NA 85.450 77.800 71.58 1.980 8.96 -5 NA 1.86 11.38

Biotechnology & Drugs MLSC Medical Discoveries, Inc. OTC Healthcare 20.920 NA NA 0.20 NA NA 104.580 85.800 0.02 -0.330 17.96 0 NA NA 0.13

Biotechnology & Drugs MRX Medicis Pharmaceutical Corporation NYSE Healthcare 1,920.640 1.04 23.26 35.11 3.94 37.47 54.700 53.700 95.00 -2.150 1.83 -5 0.34 0.90 9.54

Biotechnology & Drugs MCU Medicure Inc. (USA) AMEX Healthcare 49.220 NA NA 0.74 3.13 NA 66.650 60.600 7.64 0.200 9.07 0 NA 0.00 14.86

Biotechnology & Drugs MHUT Medi-Hut Co., Inc. OTC Healthcare 0.510 NA NA 0.04 0.03 0.34 14.470 10.400 0.00 0.000 28.11 0 NA 0.00 2.66

Biotechnology & Drugs MEDI MedImmune, Inc. NASD Healthcare 6,742.850 4.30 23.42 27.11 4.12 322.74 248.720 248.600 85.06 7.020 0.05 -1 NA 0.31 2.32

Biotechnology & Drugs TOX MEDTOX Scientific, Inc. AMEX Healthcare 67.820 NA NA 9.00 1.81 48.13 7.540 7.000 26.90 0.190 7.10 0 NA 0.36 1.19

Biotechnology & Drugs MEMY Memory Pharmaceuticals Corp. NASD Healthcare 108.760 NA NA 5.32 3.17 NA 20.450 13.300 32.65 0.000 34.96 -15 NA 0.11 3.75

Biotechnology & Drugs VIVO Meridian Bioscience, Inc. NASD Healthcare 264.290 2.03 12.50 17.55 7.97 29.20 15.060 10.600 26.88 0.060 29.62 -31 2.28 0.54 2.17

Biotechnology & Drugs MBRX Metabasis Therapeutics, Inc. NASD Healthcare 131.500 NA NA 7.25 2.80 NA 18.140 5.000 29.14 -0.780 72.43 0 NA 0.05 11.19

Biotechnology & Drugs MOGN MGi Pharma, Inc. NASD Healthcare 1,986.490 3.76 32.00 28.01 17.93 NA 70.920 66.300 91.48 2.430 6.52 -1 NA 2.36 5.68

Biotechnology & Drugs MLAR Micro Laboratories, Inc. OTC Healthcare 3.250 NA NA 0.07 NA NA 49.960 9.500 0.00 0.000 80.98 0 NA NA 0.00

Biotechnology & Drugs MII MicroIslet, Inc. AMEX Healthcare 50.750 NA NA 1.28 4.86 NA 39.650 30.500 6.23 -0.600 23.07 0 NA 0.00 38.48

Biotechnology & Drugs MLNM Millennium Pharmaceuticals, Inc. NASD Healthcare 3,714.360 -1.03 21.30 12.14 1.57 NA 305.960 302.300 70.11 14.570 1.20 0 NA 0.08 4.34

Biotechnology & Drugs MRVT Miravant Medical Technologies OTC Healthcare 36.860 NA NA 1.01 NA NA 36.500 32.500 9.20 2.100 10.95 0 NA NA 5.10

Biotechnology & Drugs MNTA Momenta Pharmaceuticals, Inc. NASD Healthcare 179.270 NA NA 7.06 2.95 NA 25.390 5.400 17.77 3.400 78.73 0 NA 0.01 16.26

Biotechnology & Drugs MUCL MultiCell Technologies, Inc. OTC Healthcare 23.360 NA NA 0.19 11.95 NA 122.960 79.800 0.01 0.000 35.10 0 NA 0.32 0.92





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BioTech Industry 31Dec04





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs MYL Mylan Laboratories Inc. NYSE Healthcare 4,757.750 1.82 11.79 17.68 2.67 16.79 269.100 228.100 68.94 31.440 15.24 0 0.68 0.01 8.45

Biotechnology & Drugs MYMX Mymetics Corporation OTC Healthcare 19.930 NA NA 0.30 NA NA 66.450 55.200 1.01 0.000 16.93 0 NA NA 0.03

Biotechnology & Drugs MYOG Myogen, Inc. NASD Healthcare 288.350 NA NA 8.07 2.36 NA 35.730 13.500 51.76 5.790 62.22 28 NA 0.02 9.63

Biotechnology & Drugs MYGN Myriad Genetics, Inc. NASD Healthcare 690.220 NA NA 22.51 4.22 NA 30.660 28.200 90.06 5.410 8.03 -1 NA 0.00 8.32

Biotechnology & Drugs NABI Nabi Biopharmaceuticals NASD Healthcare 866.880 NA NA 14.65 2.89 NA 59.170 58.200 74.15 1.120 1.64 1 NA 0.08 3.01

Biotechnology & Drugs NSTK Nastech Pharmaceutical NASD Healthcare 216.310 NA NA 12.10 17.02 NA 17.880 12.700 10.76 -0.890 28.96 -7 NA 1.21 1.70

Biotechnology & Drugs NHCT National Healthcare Technology, Inc. OTC Healthcare 0.250 NA NA 3.15 NA NA 0.080 0.020 0.00 0.000 81.01 0 NA NA NA

Biotechnology & Drugs NTOL Natrol, Inc. NASD Healthcare 44.760 NA NA 3.35 1.19 29.14 13.360 4.300 36.22 0.230 67.81 -6 NA 0.20 2.95

Biotechnology & Drugs NAII Natural Alternatives International, Inc. NASD Healthcare 54.720 NA NA 9.23 2.19 17.99 5.930 4.600 14.25 -0.110 22.42 5 NA 0.18 2.32

Biotechnology & Drugs NAWL Naturewell, Inc. OTC Healthcare 0.590 NA NA 0.01 NA NA 118.290 72.200 0.00 0.000 39.24 0 NA NA 0.02

Biotechnology & Drugs NTY NBTY, Inc. NYSE Healthcare 1,610.110 0.99 14.00 24.01 2.52 14.83 67.060 53.900 72.90 1.210 19.62 6 NA 0.48 2.66

Biotechnology & Drugs NEOG Neogen Corporation NASD Healthcare 183.240 1.63 17.50 22.65 3.68 35.50 8.090 6.900 27.91 0.120 14.71 -8 NA 0.05 4.78

Biotechnology & Drugs NEOL NeoPharm, Inc. NASD Healthcare 291.410 NA NA 12.51 4.05 NA 23.290 16.900 70.57 -3.040 27.45 0 NA 0.00 8.72

Biotechnology & Drugs NEOP Neoprobe Corporation OTC Healthcare 34.100 NA NA 0.59 4.92 NA 58.290 54.600 0.61 -0.590 6.33 8 NA 0.03 5.41

Biotechnology & Drugs NERX NeoRx Corporation NASD Healthcare 64.500 NA NA 2.09 2.47 NA 30.860 28.000 6.40 -0.630 9.27 0 NA 0.17 11.71

Biotechnology & Drugs NTEC Neose Technologies, Inc. NASD Healthcare 166.100 NA NA 6.72 2.31 NA 24.720 22.100 64.48 0.420 10.59 1 NA 0.25 3.81

Biotechnology & Drugs NTII Neurobiological Tech. NASD Healthcare 117.840 NA NA 4.42 4.82 NA 26.660 17.400 24.44 1.260 34.74 2 NA 0.00 11.61

Biotechnology & Drugs NRMX Neurochem Inc. (USA) NASD Healthcare 530.840 NA NA 17.53 11.63 NA 30.280 19.900 25.97 -1.600 34.28 0 NA 0.20 4.93

Biotechnology & Drugs NBIX Neurocrine Biosciences, Inc. NASD Healthcare 1,797.730 -1.97 25.00 49.30 4.36 NA 36.470 34.800 90.65 0.950 4.57 -5 NA 0.17 4.67

Biotechnology & Drugs NRGN Neurogen Corporation NASD Healthcare 320.690 NA NA 9.36 2.11 NA 34.260 26.500 36.97 0.060 22.65 -2 NA 0.09 12.70

Biotechnology & Drugs NRGX Neurologix, Inc. OTC Healthcare 34.910 NA NA 1.55 9.41 NA 22.520 12.400 30.33 6.830 44.94 0 NA 0.01 12.04

Biotechnology & Drugs NRPH New River Pharmaceuticals, Inc. NASD Healthcare 265.730 -0.41 40.00 14.96 9.40 NA 17.760 4.200 13.34 2.370 76.36 3 NA 0.00 15.28

Biotechnology & Drugs BBAL New York Health Care, Inc. OTC Healthcare 12.720 NA NA 0.51 2.42 NA 24.940 22.200 0.00 0.000 10.99 0 NA 0.00 0.91

Biotechnology & Drugs NEXM NexMed, Inc. NASD Healthcare 69.280 NA NA 1.50 8.08 NA 46.190 44.000 23.94 -1.060 4.73 4 NA 0.83 3.25

Biotechnology & Drugs NTMD NitroMed, Inc. NASD Healthcare 698.800 NA NA 26.65 10.97 NA 26.220 12.000 60.35 6.270 54.24 -3 NA 0.00 4.98

Biotechnology & Drugs NASI North American Scientific, Inc. NASD Healthcare 87.630 -0.21 20.00 5.39 1.17 NA 16.260 12.900 48.33 1.330 20.65 1 NA 0.00 1.62

Biotechnology & Drugs NFLD Northfield Laboratories NASD Healthcare 482.670 NA NA 22.55 13.13 NA 21.400 17.600 17.82 0.460 17.77 0 NA 0.00 24.86

Biotechnology & Drugs NWBT Northwest Biotherapeutics OTC Healthcare 0.740 NA NA 0.04 NA NA 19.030 10.600 0.00 0.000 44.30 0 NA NA 0.03

Biotechnology & Drugs NVAX Novavax, Inc. NASD Healthcare 128.950 NA NA 3.26 2.96 NA 39.550 29.300 14.29 -1.560 25.92 4 NA 0.84 4.14

Biotechnology & Drugs NOVN Noven Pharmaceuticals NASD Healthcare 399.880 1.52 22.50 17.06 3.18 28.77 23.440 22.300 79.47 -0.320 4.86 -1 NA 0.00 3.63

Biotechnology & Drugs NVO Novo Nordisk A/S (ADR) NYSE Healthcare 18,348.090 NA NA 54.26 NA 21.24 338.150 241.700 1.61 -0.930 28.52 0 1.37 NA NA

Biotechnology & Drugs NVGN Novogen Limited (ADR) NASD Healthcare 422.220 NA NA 22.08 7.92 NA 19.120 16.060 2.12 0.150 16.01 0 NA 0.03 10.89

Biotechnology & Drugs NPSP NPS Pharmaceuticals, Inc. NASD Healthcare 708.740 NA NA 18.28 17.81 NA 38.770 37.600 95.00 1.020 3.02 -34 NA 4.83 6.92

Biotechnology & Drugs NPHC Nutra Pharma Corp. OTC Healthcare 13.520 NA NA 0.25 17.38 NA 54.100 47.600 NA NA 12.01 NA NA 0.13 0.10

Biotechnology & Drugs NUTR Nutraceutical Int'l Corp. NASD Healthcare 177.270 NA NA 15.41 2.47 13.44 11.500 9.200 65.38 -0.250 20.02 -2 NA 0.09 2.79

Biotechnology & Drugs NXXI Nutrition 21, Inc. NASD Healthcare 39.130 NA NA 1.03 3.42 NA 37.990 34.400 1.92 -0.480 9.46 -2 NA 0.00 1.85

Biotechnology & Drugs NUVO Nuvelo, Inc. NASD Healthcare 317.310 NA NA 9.85 5.42 NA 32.210 29.800 50.96 1.040 7.50 0 NA 0.28 2.68

Biotechnology & Drugs NYMX Nymox Pharmaceutical Corporation NASD Healthcare 70.760 NA NA 2.81 52.15 NA 25.180 11.300 1.22 -0.280 55.13 0 NA 0.37 0.28

Biotechnology & Drugs ONCY Oncolytics Biotech, Inc. (USA) NASD Healthcare 135.690 NA NA 4.59 5.87 NA 29.560 29.300 7.77 0.890 0.89 0 NA 0.01 17.66

Biotechnology & Drugs ONCR Oncor, Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 33.550 24.500 0.15 0.000 26.98 0 NA NA 5.83

Biotechnology & Drugs ONXX Onyx Pharmaceuticals, Inc. NASD Healthcare 1,142.210 NA NA 32.39 5.88 NA 35.260 24.700 95.00 0.950 29.96 -18 NA 0.10 11.22

Biotechnology & Drugs ONI Oragenics, Inc. AMEX Healthcare 56.110 NA NA 3.85 12.31 NA 14.570 6.400 NA NA 56.08 NA NA 0.00 13.77

Biotechnology & Drugs ORCH Orchid Biosciences, Inc. NASD Healthcare 257.330 -1.14 30.00 11.50 4.87 NA 22.380 21.300 47.16 1.720 0.82 5 NA 0.01 2.55

Biotechnology & Drugs ORPH Orphan Medical, Inc. NASD Healthcare 103.040 -0.17 41.03 9.02 7.50 NA 11.420 11.300 39.30 -0.090 1.08 -2 NA 0.00 2.85

Biotechnology & Drugs OSCI Oscient Pharmaceuticals Corporation NASD Healthcare 274.460 NA NA 3.65 1.92 NA 75.190 62.400 40.91 -0.220 17.01 -8 NA 1.23 7.82

Biotechnology & Drugs OSIP OSI Pharmaceuticals, Inc. NASD Healthcare 3,789.990 -4.12 10.00 74.85 21.15 NA 50.630 49.900 87.47 3.400 1.45 -62 NA 0.97 5.83

Biotechnology & Drugs OXGN OXiGENE, Inc. NASD Healthcare 91.980 NA NA 5.50 2.94 NA 16.720 16.100 17.44 -0.490 3.73 3 NA 0.00 10.21

Biotechnology & Drugs OXIS OXIS International, Inc. OTC Healthcare 14.910 NA NA 0.55 NA NA 27.110 21.100 5.33 0.930 22.16 0 NA NA 0.56

Biotechnology & Drugs PBME Pacific Biometrics, Inc. OTC Healthcare 15.140 NA NA 1.16 NA NA 13.050 7.200 0.00 0.000 44.82 -3 NA NA 1.21

Biotechnology & Drugs PHLI PacificHealth Laboratories, Inc. OTC Healthcare 6.960 NA NA 0.68 3.19 NA 10.240 7.500 0.01 0.000 21.85 0 NA 0.21 2.05

Biotechnology & Drugs PTIE Pain Therapeutics, Inc. NASD Healthcare 314.430 NA NA 7.21 6.46 NA 43.610 31.800 37.27 0.660 27.08 1 NA 0.00 7.57

Biotechnology & Drugs PTN Palatin Technologies, Inc AMEX Healthcare 143.590 NA NA 2.66 7.24 NA 53.980 50.600 21.54 -2.100 6.26 2 NA 0.00 3.79

Biotechnology & Drugs PGNT Paligent Inc. OTC Healthcare 5.360 NA NA 0.17 NA NA 32.490 14.600 0.09 0.000 55.06 0 NA NA 0.32

Biotechnology & Drugs PRX Par Pharmaceutical Companies, Inc NYSE Healthcare 1,401.830 1.27 13.63 41.38 3.46 23.75 33.880 33.800 85.54 -0.310 0.23 9 NA 0.50 3.18

Biotechnology & Drugs PRLN Paracelsian, Inc. OTC Healthcare 0.260 NA NA 0.01 NA NA 23.950 16.000 0.69 0.000 33.21 0 NA NA 0.03

Biotechnology & Drugs PRXL PAREXEL International NASD Healthcare 527.670 1.10 18.50 20.30 2.10 37.11 25.990 25.900 95.00 0.270 0.36 -1 NA 0.00 1.75

Biotechnology & Drugs PPRX Peninsula Pharmaceuticals, Inc. NASD Healthcare 0.000 NA NA 0.00 NA NA 23.030 0.000 NA NA 100.00 NA NA NA NA

Biotechnology & Drugs PPCO Penwest Pharmaceuticals NASD Healthcare 221.840 NA NA 11.96 4.28 NA 18.550 18.200 82.47 1.310 1.88 0 NA 0.00 12.67

Biotechnology & Drugs PPHM Peregrine Pharmaceuticals NASD Healthcare 165.370 NA NA 1.17 17.76 NA 141.350 134.000 13.44 -0.030 5.36 -8 NA 0.00 2.57

Biotechnology & Drugs PRGO Perrigo Company NASD Healthcare 1,229.920 1.75 10.00 17.27 2.21 15.28 71.220 57.300 81.57 -0.250 19.54 -8 0.93 0.02 2.80

Biotechnology & Drugs PHFR Pharmaceutical Formulations, Inc. OTC Healthcare 42.980 NA NA 0.50 NA NA 85.960 10.800 0.00 0.000 87.44 -1 NA NA 0.83

Biotechnology & Drugs PPDI Pharmaceutical Product Development, Inc. NASD Healthcare 2,334.250 1.17 20.44 41.29 3.92 41.58 56.530 48.100 82.97 0.890 14.92 -4 NA 0.01 1.82

Biotechnology & Drugs PCOP Pharmacopeia Drug Discovery, Inc. NASD Healthcare 73.450 NA NA 5.97 1.67 NA 12.300 12.300 72.80 0.190 0.03 2 NA 0.00 4.82

Biotechnology & Drugs PCYC Pharmacyclics, Inc. NASD Healthcare 205.740 NA NA 10.47 2.21 NA 19.650 19.400 67.21 -0.160 1.28 -1 NA 0.00 24.47

Biotechnology & Drugs PPRT PharmaPrint Inc. OTC Healthcare 0.140 NA NA 0.01 NA NA 23.980 22.500 0.00 0.000 6.19 0 NA NA 0.06





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Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs PHRM Pharmion Corporation NASD Healthcare 1,336.210 -2.05 30.00 42.21 3.87 NA 31.660 18.700 63.15 5.510 40.93 0 NA 0.00 9.62

Biotechnology & Drugs PARS Pharmos Corporation NASD Healthcare 133.670 NA NA 1.42 2.70 NA 94.130 93.200 15.77 1.880 0.99 -14 NA 0.18 4.28

Biotechnology & Drugs PLTT Pilot Therapeutics Holdings, Inc. OTC Healthcare 0.810 NA NA 0.07 NA NA 11.540 2.600 0.00 0.000 77.48 0 NA NA 0.25

Biotechnology & Drugs PLRS Pluristem Life Systems, Inc. OTC Healthcare 5.510 NA NA 0.21 51.94 NA 26.860 19.900 NA NA 25.91 NA NA 0.03 0.82

Biotechnology & Drugs POTP Point Therapeutics, Inc. OTC Healthcare 97.850 NA NA 5.36 5.99 NA 18.260 16.800 22.40 0.040 7.98 0 NA 0.00 7.93

Biotechnology & Drugs POLXF Polydex Pharmaceuticals Limited NASD Healthcare 18.250 NA NA 6.00 2.13 10.35 3.040 2.200 1.25 0.020 27.68 0 NA 0.14 3.58

Biotechnology & Drugs PROAQ Polymer Research Corp. of America OTC Healthcare 0.640 NA NA 0.30 2.04 NA 2.130 0.900 0.14 0.000 57.73 0 NA 6.88 0.69

Biotechnology & Drugs PWRM Power3 Medical Products, Inc. OTC Healthcare 52.910 NA NA 0.85 NA NA 62.250 9.300 0.02 0.010 85.06 -2 NA NA 0.10

Biotechnology & Drugs POZN POZEN Inc. NASD Healthcare 209.760 NA NA 7.27 5.23 181.75 28.850 21.800 52.49 -0.920 24.45 0 NA 0.00 17.86

Biotechnology & Drugs PRAI PRA International NASD Healthcare 541.420 NA NA 24.78 5.65 33.35 21.850 6.000 0.00 0.000 72.54 -11 NA 0.63 0.88

Biotechnology & Drugs PRCS Praecis Pharmaceuticals NASD Healthcare 99.520 NA NA 1.90 0.79 NA 52.380 51.100 62.59 -5.820 2.44 4 NA 0.26 12.06

Biotechnology & Drugs PRAN Prana Biotechnology Limited (ADR) NASD Healthcare 67.900 NA NA 4.06 1.57 NA 16.730 14.860 12.52 -0.130 11.15 0 NA 0.00 11.00

Biotechnology & Drugs PBIO Pressure BioSciences, Inc. NASD Healthcare 23.100 NA NA 3.37 0.92 NA 6.850 6.200 3.41 0.000 9.79 0 NA 0.00 5.45

Biotechnology & Drugs PRCY ProCyte Corporation OTC Healthcare 25.780 NA NA 1.63 1.32 3.69 15.820 15.200 2.07 0.100 3.90 0 NA 0.00 7.57

Biotechnology & Drugs PGLAF Progen Industries Limited (USA) NASD Healthcare 119.790 NA NA 3.47 9.19 NA 34.520 30.700 0.18 -0.020 11.07 0 NA 0.00 8.56

Biotechnology & Drugs PGNX Progenics Pharmaceuticals NASD Healthcare 295.610 NA NA 17.16 7.21 NA 17.230 14.500 70.39 0.560 15.83 -3 NA 0.00 4.40

Biotechnology & Drugs PRW Pro-Pharmaceuticals, Inc. AMEX Healthcare 68.290 NA NA 2.50 5.59 NA 27.320 20.900 3.60 0.500 23.49 3 NA 0.00 20.63

Biotechnology & Drugs PDLI Protein Design Labs, Inc. NASD Healthcare 1,973.160 NA NA 20.66 4.65 NA 95.510 92.500 93.52 7.770 3.15 -18 NA 0.61 9.16

Biotechnology & Drugs PPTI Protein Polymer Technologies, Inc. OTC Healthcare 27.410 NA NA 0.70 NA NA 39.440 6.300 0.01 0.000 84.03 0 NA NA 0.18

Biotechnology & Drugs PPMD Protide Pharmaceuticals OTC Healthcare 0.440 NA NA 0.11 1.85 NA 4.030 3.400 NA NA 15.61 NA NA 0.30 2.61

Biotechnology & Drugs PVLS Provalis PLC (ADR) NASD Healthcare 48.500 NA NA 4.40 1.75 NA 11.020 9.150 0.00 0.000 17.01 0 NA 0.00 1.41

Biotechnology & Drugs PMD Psychemedics Corp. AMEX Healthcare 66.390 NA NA 12.95 10.89 25.80 5.130 5.000 18.12 0.060 2.48 0 2.47 0.00 2.88

Biotechnology & Drugs PURW Pure World, Inc. NASD Healthcare 12.670 NA NA 1.56 0.74 27.86 8.120 4.100 7.12 -0.010 49.51 0 NA 0.12 2.17

Biotechnology & Drugs QLTI QLT Inc. (USA) NASD Healthcare 1,119.180 0.84 21.40 16.08 2.16 21.10 69.600 56.100 80.90 2.210 19.40 0 NA 0.33 31.04

Biotechnology & Drugs QSC Questcor Pharmaceuticals AMEX Healthcare 27.120 NA NA 0.53 7.46 NA 51.170 34.300 6.85 -0.130 32.97 5 NA 0.38 1.54

Biotechnology & Drugs REGN Regeneron Pharmaceuticals NASD Healthcare 513.390 NA NA 9.21 2.86 37.75 55.740 33.300 56.85 0.850 40.26 -6 NA 1.12 8.67

Biotechnology & Drugs RGRX RegeneRx Biopharmaceut. OTC Healthcare 137.750 NA NA 4.05 60.33 NA 34.010 24.500 3.17 0.000 27.96 0 NA 0.00 8.82

Biotechnology & Drugs RNVS Renovis, Inc. NASD Healthcare 349.650 NA NA 14.38 3.82 NA 24.310 13.100 22.94 0.220 46.12 -7 NA 0.04 10.45

Biotechnology & Drugs RGEN Repligen Corporation NASD Healthcare 86.570 -1.01 15.00 2.88 3.48 NA 30.060 26.300 12.23 -0.960 12.51 1 NA 0.00 8.55

Biotechnology & Drugs RIGL Rigel Pharmaceuticals, Inc. NASD Healthcare 477.710 NA NA 24.42 7.48 NA 19.560 7.800 63.55 3.970 60.13 -45 NA 0.04 9.58

Biotechnology & Drugs STCX SalesTactix, Inc. OTC Healthcare 0.410 NA NA 0.06 NA NA 6.840 5.500 NA NA 19.54 NA NA NA NA

Biotechnology & Drugs SLXP Salix Pharmaceuticals Ltd NASD Healthcare 639.200 4.28 25.00 17.59 7.82 NA 36.340 30.500 90.04 2.190 16.07 6 NA 0.00 3.92

Biotechnology & Drugs LIV Samaritan Pharmaceuticals, Inc. AMEX Healthcare 128.190 NA NA 0.98 21.31 NA 130.800 124.900 0.59 0.130 4.51 0 NA 0.00 9.02

Biotechnology & Drugs SGMO Sangamo Biosciences, Inc. NASD Healthcare 151.120 NA NA 6.00 4.32 NA 25.190 12.800 47.89 -0.600 49.18 -19 NA 0.00 25.87

Biotechnology & Drugs SGNC Sanguine Corporation OTC Healthcare 10.430 NA NA 0.27 NA NA 38.640 27.000 NA NA 30.12 NA NA NA 0.00

Biotechnology & Drugs SNY Sanofi-Aventis (ADR) NYSE Healthcare 58,701.130 178.00 0.10 40.05 6.61 18.95 1,465.700 527.600 6.08 39.110 64.00 0 0.31 0.05 2.74

Biotechnology & Drugs SNTS Santarus, Inc. NASD Healthcare 327.560 -0.11 30.00 9.04 2.80 NA 36.230 29.200 41.13 4.950 19.42 3 NA 0.00 11.51

Biotechnology & Drugs SVNT Savient Pharmaceuticals, Inc. NASD Healthcare 163.800 -0.23 20.00 2.71 1.07 NA 60.440 53.800 40.11 -1.350 10.99 0 NA 0.05 1.42

Biotechnology & Drugs SCLN SciClone Pharmaceuticals NASD Healthcare 165.250 NA NA 3.70 2.87 NA 44.660 43.000 24.31 -0.520 3.72 0 NA 0.10 11.03

Biotechnology & Drugs DDD SCOLR Pharma Inc. AMEX Healthcare 149.770 NA NA 4.91 14.44 NA 30.500 26.300 2.72 0.770 13.78 5 NA 0.01 14.97

Biotechnology & Drugs SGEN Seattle Genetics, Inc. NASD Healthcare 273.940 -0.24 15.00 6.53 2.40 NA 41.950 30.200 50.97 1.280 28.01 -34 NA 0.00 5.95

Biotechnology & Drugs STLT Select Therapeutics Inc. OTC Healthcare 0.000 NA NA 0.00 NA NA 17.560 15.000 0.00 0.000 14.58 0 NA NA NA

Biotechnology & Drugs SNT Senesco Technologies, Inc. AMEX Healthcare 48.260 NA NA 3.50 11.54 NA 13.790 12.200 13.60 0.040 11.53 0 NA 0.00 8.86

Biotechnology & Drugs SNTKY Senetek PLC (ADR) OTC Healthcare 14.560 NA NA 0.24 NA NA 60.660 60.500 0.41 0.200 0.10 2 NA NA 2.50

Biotechnology & Drugs SNMX Senomyx Inc. NASD Healthcare 208.660 NA NA 8.28 4.88 NA 25.200 6.000 53.16 5.150 76.19 0 NA 0.00 13.99

Biotechnology & Drugs SGHL Sentigen Holding Corp. NASD Healthcare 52.440 NA NA 7.02 5.19 NA 7.470 5.000 1.07 0.030 33.07 0 NA 0.10 4.60

Biotechnology & Drugs SEPR Sepracor Inc. NASD Healthcare 6,238.980 NA NA 59.37 NA NA 105.090 102.600 92.85 4.030 2.37 -1 NA NA 4.79

Biotechnology & Drugs SQNM Sequenom, Inc. NASD Healthcare 57.160 NA NA 1.44 1.29 NA 39.690 38.400 20.29 -2.300 3.25 1 NA 0.20 3.11

Biotechnology & Drugs SRLS SeraCare Life Sciences NASD Healthcare 132.490 NA NA 14.92 3.18 33.91 8.880 4.400 12.74 0.130 44.51 0 NA 0.65 2.41

Biotechnology & Drugs SERO Serologicals Corporation NASD Healthcare 654.850 1.82 17.00 22.12 3.31 29.22 29.600 29.100 95.00 1.390 1.70 -8 NA 0.68 4.65

Biotechnology & Drugs SRA Serono S.A. (ADR) NYSE Healthcare 9,777.170 1.45 13.90 16.32 3.70 19.71 599.090 260.000 1.39 -1.030 56.60 0 0.97 0.23 2.59

Biotechnology & Drugs SFCC SFBC International, Inc. NASD Healthcare 583.250 1.13 28.50 39.50 3.98 34.08 14.770 12.300 68.00 1.260 16.70 -4 NA 1.09 10.25

Biotechnology & Drugs SHPH Shaman Pharmaceuticals Inc. OTC Healthcare 0.010 NA NA 0.00 NA NA 103.460 46.600 0.11 0.010 54.96 0 NA NA 0.11

Biotechnology & Drugs SHPGY Shire Pharmaceuticals Group plc (ADR) NASD Healthcare 5,153.420 0.98 16.00 31.95 2.44 16.16 161.300 156.370 22.93 -1.290 3.06 -1 0.17 0.00 4.14

Biotechnology & Drugs SIGA SIGA Technologies, Inc. NASD Healthcare 40.670 NA NA 1.66 5.35 NA 24.500 14.400 4.92 0.020 41.23 2 NA 0.00 3.68

Biotechnology & Drugs SVA Sinovac Biotechnology Ltd. AMEX Healthcare 0.000 NA NA 0.00 11.44 NA 34.770 14.600 0.00 -0.020 58.01 0 NA 0.21 1.67

Biotechnology & Drugs RNAI Sirna Therapeutics, Inc. NASD Healthcare 120.040 NA NA 3.17 3.64 NA 37.870 12.300 51.09 2.730 67.52 0 NA 0.09 5.23

Biotechnology & Drugs SKYE SkyePharma plc (ADR) NASD Healthcare 779.050 NA NA 12.52 5.45 NA 62.220 60.980 4.38 0.840 2.00 0 NA 1.01 0.54

Biotechnology & Drugs SNUS Sonus Pharmaceuticals, Inc. NASD Healthcare 75.360 NA NA 3.53 3.09 NA 21.350 20.900 25.18 0.340 2.10 0 NA 0.01 10.69

Biotechnology & Drugs DIAGF Spectral Diagnostics, Inc (USA) NASD Healthcare 15.850 NA NA 0.93 2.47 NA 17.130 15.400 1.47 -0.850 10.13 0 NA 1.08 2.89

Biotechnology & Drugs SPPI Spectrum Pharmaceuticals, Inc. NASD Healthcare 96.500 NA NA 6.66 2.55 NA 14.490 13.400 24.00 -0.080 7.52 2 NA 0.00 15.85

Biotechnology & Drugs SLRXF Stellar International Inc. (USA) OTC Healthcare 46.000 NA NA 2.04 12.93 NA 22.550 13.600 0.00 -0.130 39.69 0 NA 0.00 5.36

Biotechnology & Drugs STEM StemCells, Inc. NASD Healthcare 229.510 NA NA 4.23 11.82 NA 54.260 52.500 11.54 0.630 5.92 0 NA 0.10 6.67

Biotechnology & Drugs STGN Stratagene Corporation NASD Healthcare 170.620 1.48 15.00 7.75 3.24 23.41 22.020 3.900 16.21 0.860 82.29 -10 NA 0.24 1.77

Biotechnology & Drugs SUPG SuperGen, Inc. NASD Healthcare 353.990 NA NA 7.05 5.78 NA 50.210 47.600 37.43 -2.370 5.20 0 NA 0.04 3.23





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BioTech Industry 31Dec04





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Biotechnology & Drugs SWME Swiss Medica, Inc. OTC Healthcare 23.600 NA NA 0.39 15.61 NA 60.510 30.800 0.00 0.000 49.10 0 NA 0.00 3.82

Biotechnology & Drugs SYMBA Symbollon Pharmaceuticals OTC Healthcare 10.270 NA NA 1.70 8.23 NA 6.040 4.700 0.17 0.010 22.18 4 NA 0.00 9.36

Biotechnology & Drugs SBIO Synbiotics Corporation OTC Healthcare 3.120 NA NA 0.15 2.20 NA 20.820 8.600 1.18 0.000 58.70 -1 NA 1.04 1.80

Biotechnology & Drugs SYBD Synthetic Blood Int'l Inc OTC Healthcare 28.440 NA NA 0.25 30.54 NA 116.080 114.000 0.03 0.000 1.79 0 NA 0.00 1.70

Biotechnology & Drugs TNOX Tanox, Inc. NASD Healthcare 668.370 NA NA 15.20 2.94 NA 43.970 23.900 53.64 4.580 45.65 -5 NA 0.02 35.12

Biotechnology & Drugs TPPH Tapestry Pharmaceuticals, Inc. NASD Healthcare 32.300 NA NA 0.97 0.91 NA 33.300 28.700 15.54 0.430 13.90 1 NA 0.17 6.68

Biotechnology & Drugs TGEN Targeted Genetics Corp. NASD Healthcare 126.550 NA NA 1.55 2.75 NA 81.650 80.100 4.80 -0.130 1.90 0 NA 0.25 6.62

Biotechnology & Drugs TARO Taro Pharmaceutical Industries Ltd. NASD Healthcare 997.120 1.97 47.33 34.03 2.77 44.66 29.300 26.100 60.88 0.330 10.93 0 NA 0.70 2.93

Biotechnology & Drugs TCPI TCPI, Inc. OTC Healthcare 0.060 NA NA 0.00 0.01 NA 96.910 91.100 0.00 0.000 5.99 0 NA 0.01 0.64

Biotechnology & Drugs TECH Techne Corporation NASD Healthcare 1,607.100 2.25 11.67 38.90 5.12 29.74 41.310 38.700 81.96 0.060 6.33 -3 NA 0.05 9.07

Biotechnology & Drugs TELK Telik, Inc. NASD Healthcare 837.770 -0.22 54.00 19.14 5.70 NA 43.770 43.700 92.72 1.360 0.16 4 NA 0.02 10.08

Biotechnology & Drugs TRCA Tercica, Inc. NASD Healthcare 245.590 NA NA 10.00 4.24 NA 24.560 8.800 27.25 0.530 64.17 1 NA 0.00 10.42

Biotechnology & Drugs TEVA NASD

Teva Pharmaceutical Industries Ltd (ADR) Healthcare 18,351.960 0.87 24.02 29.86 3.60 94.79 614.600 571.600 51.96 -52.280 7.00 0 0.68 0.39 2.11

Biotechnology & Drugs IMNR The Immune Response Corp. NASD Healthcare 78.250 NA NA 1.61 NA NA 48.600 17.000 3.85 -0.490 65.02 2 NA 0.61 3.97

Biotechnology & Drugs MDCO The Medicines Company NASD Healthcare 1,385.690 3.75 22.50 28.80 8.67 97.96 48.110 42.800 95.00 2.810 11.05 -20 NA 0.00 6.91

Biotechnology & Drugs QGLY The Quigley Corporation NASD Healthcare 98.070 NA NA 8.43 5.11 240.80 11.640 8.800 2.52 0.010 24.38 -4 NA 0.00 5.47

Biotechnology & Drugs TGX Theragenics Corporation NYSE Healthcare 121.700 NA NA 4.06 0.87 NA 29.980 29.600 57.82 -1.310 1.25 0 NA 0.00 19.06

Biotechnology & Drugs THRX Theravance, Inc NASD Healthcare 949.500 NA NA 17.90 7.51 NA 53.040 6.200 0.00 0.000 88.31 5 NA 0.05 5.47

Biotechnology & Drugs TWTI Third Wave Technologies NASD Healthcare 349.850 24.57 25.00 8.60 5.41 318.52 40.680 24.400 59.36 2.570 40.02 0 NA 0.16 3.83

Biotechnology & Drugs TBGU Tiens Biotech Group (USA), Inc. OTC Healthcare 499.340 NA NA 7.00 8.68 19.50 71.330 4.300 0.00 0.000 93.97 0 NA 0.19 10.42

Biotechnology & Drugs TTP Titan Pharmaceuticals AMEX Healthcare 104.010 NA NA 3.22 2.54 NA 32.300 31.700 26.55 0.770 1.87 1 NA 0.00 13.35

Biotechnology & Drugs TRGNY Transgene (ADR) NASD Healthcare 85.350 NA NA 2.80 2.74 NA 30.470 7.270 0.00 0.000 76.13 0 NA 0.00 5.50

Biotechnology & Drugs TKTX Transkaryotic Therapies NASD Healthcare 882.880 NA NA 25.39 4.29 NA 34.770 27.700 81.23 2.420 20.34 0 NA 0.46 9.66

Biotechnology & Drugs TRMS Trimeris, Inc. NASD Healthcare 309.720 NA NA 14.17 8.87 NA 21.860 18.800 95.00 1.030 13.99 18 NA 0.00 5.44

Biotechnology & Drugs TRIB Trinity Biotech plc (ADR) NASD Healthcare 137.820 NA NA 2.96 1.46 43.53 46.560 41.500 9.34 0.470 10.87 0 NA 0.15 5.34

Biotechnology & Drugs TMGU Trinity Medical Group USA, Inc. OTC Healthcare 0.100 NA NA 0.01 NA NA 19.520 9.900 NA NA 49.28 NA NA NA 0.34

Biotechnology & Drugs TRPS Tripos, Inc. NASD Healthcare 49.530 NA NA 5.33 1.75 NA 9.290 7.900 51.97 -0.360 14.99 4 NA 0.39 1.08

Biotechnology & Drugs UGNE Unigene Laboratories OTC Healthcare 175.480 NA NA 2.25 NA NA 77.990 72.600 0.27 0.000 6.91 -1 NA NA 0.26

Biotechnology & Drugs UTHR United Therapeutics Corporation NASD Healthcare 1,006.610 1.44 54.50 45.15 5.60 217.07 22.290 21.100 95.00 0.770 5.36 -61 NA 0.00 7.61

Biotechnology & Drugs UG United-Guardian, Inc. AMEX Healthcare 41.160 NA NA 8.35 3.06 15.35 4.930 2.800 12.37 0.020 43.21 -2 2.16 0.00 7.67

Biotechnology & Drugs VITX V.I. Technologies, Inc. NASD Healthcare 35.400 NA NA 0.65 3.75 NA 54.460 37.000 6.86 0.500 32.06 0 NA 0.00 2.21

Biotechnology & Drugs VRX Valeant Pharmaceuticals International NYSE Healthcare 2,216.690 21.82 21.00 26.35 4.20 NA 84.120 69.800 95.00 0.920 17.03 0 1.18 1.50 4.46

Biotechnology & Drugs VLTS Valentis, Inc. NASD Healthcare 32.750 NA NA 2.50 2.08 NA 13.100 9.800 40.49 -0.950 25.18 -20 NA 0.00 5.10

Biotechnology & Drugs VAPH Vaso Active Pharmaceuticals, Inc. OTC Healthcare 4.750 NA NA 0.46 1.86 NA 10.330 2.800 0.50 -0.010 72.89 0 NA 0.00 6.09

Biotechnology & Drugs VXGN VaxGen, Inc. OTC Healthcare 426.330 NA NA 17.00 15.97 NA 25.080 9.300 33.22 -4.430 62.92 0 NA 0.00 1.47

Biotechnology & Drugs VNLS Vernalis plc (ADR) NASD Healthcare 227.400 NA NA 3.20 5.13 NA 71.060 49.750 1.78 1.250 29.99 0 NA 0.98 1.02

Biotechnology & Drugs VRTX Vertex Pharmaceuticals NASD Healthcare 848.880 NA NA 10.57 11.40 NA 80.310 78.600 85.53 3.390 2.13 -35 NA 4.61 3.22

Biotechnology & Drugs VICL Vical Incorporated NASD Healthcare 110.390 NA NA 4.70 1.26 NA 23.490 23.100 34.00 0.040 1.65 6 NA 0.12 9.24

Biotechnology & Drugs MICU Vicuron Pharmaceuticals, Inc. NASD Healthcare 1,047.700 NA NA 17.41 6.60 NA 60.180 56.000 75.35 10.900 6.94 -4 NA 0.05 4.59

Biotechnology & Drugs VION Vion Pharmaceuticals,Inc. NASD Healthcare 259.790 NA NA 4.69 6.44 NA 55.390 54.400 50.86 1.040 1.88 -27 NA 0.00 9.61

Biotechnology & Drugs VGNI Viragen International, Inc. OTC Healthcare 15.470 NA NA 0.21 2.42 NA 73.670 14.200 NA NA 80.72 NA NA 0.12 3.57

Biotechnology & Drugs VRA Viragen, Inc. AMEX Healthcare 36.570 NA NA 1.00 1.46 NA 36.570 36.100 1.53 -0.620 1.28 1 NA 0.57 12.43

Biotechnology & Drugs VRAL Viral Genetics, Inc. OTC Healthcare 33.560 NA NA 0.42 11.13 NA 79.890 27.200 NA NA 65.95 NA NA 0.40 0.10

Biotechnology & Drugs VBAC Virbac Corporation OTC Healthcare 74.520 NA NA 3.35 2.12 31.60 22.240 8.100 2.63 0.140 63.59 0 NA 0.30 3.94

Biotechnology & Drugs VLGC ViroLogic, Inc. NASD Healthcare 318.930 NA NA 2.79 8.90 NA 114.310 103.200 54.83 0.300 9.72 0 NA 0.04 2.22

Biotechnology & Drugs VPHM ViroPharma Incorporated NASD Healthcare 86.880 NA NA 3.25 NA NA 26.730 23.800 28.75 -1.160 10.97 0 NA NA 20.83

Biotechnology & Drugs VTLV Vital Living, Inc. OTC Healthcare 12.690 NA NA 0.16 0.46 NA 79.320 48.400 NA NA 38.98 NA NA 0.11 0.63

Biotechnology & Drugs VVUS VIVUS, Inc. NASD Healthcare 169.520 NA NA 4.45 5.40 NA 38.090 35.000 41.91 -0.090 8.12 4 NA 0.07 2.89

Biotechnology & Drugs VYRX Vyrex Corporation OTC Healthcare 1.190 NA NA 0.14 NA NA 8.490 7.400 0.00 0.000 12.87 0 NA NA 0.28

Biotechnology & Drugs WCRX Warner Chilcott plc (ADR) NASD Healthcare 3,091.680 0.77 20.35 65.48 2.78 26.07 47.220 39.200 3.61 -1.700 16.98 0 0.32 0.22 1.46

Biotechnology & Drugs WPI Watson Pharmaceuticals NYSE Healthcare 3,592.770 1.73 10.69 32.81 1.65 24.29 109.500 104.400 79.15 2.380 4.66 -1 NA 0.27 5.24

Biotechnology & Drugs WFHCQ Women First HealthCare OTC Healthcare 0.030 NA NA 0.00 NA NA 26.660 16.000 0.52 -0.110 39.98 0 NA NA 0.16

Biotechnology & Drugs XCYT Xcyte Therapies, Inc. NASD Healthcare 46.150 NA NA 2.76 1.52 NA 16.720 9.500 21.95 0.620 43.19 0 NA 0.13 6.15

Biotechnology & Drugs XKEM Xechem International, Inc. OTC Healthcare 4.660 NA NA 0.02 NA NA 258.670 245.700 0.19 0.000 5.01 0 NA NA 0.51

Biotechnology & Drugs XNVA Xenova Group plc (ADR) NASD Healthcare 56.090 NA NA 1.30 0.82 NA 43.150 42.720 0.12 -0.050 0.99 0 NA 0.00 2.95

Biotechnology & Drugs XOMA XOMA Limited NASD Healthcare 221.620 NA NA 2.59 NA NA 85.570 84.500 43.29 -3.540 1.25 -2 NA NA 2.06

Biotechnology & Drugs XTRN Xtrana, Inc. OTC Healthcare 3.310 NA NA 0.20 1.12 3.39 16.530 13.800 0.09 0.020 16.53 0 NA 0.01 14.99

Biotechnology & Drugs YMI YM BioSciences Inc. (USA) AMEX Healthcare 52.330 NA NA 3.00 3.85 NA 17.440 17.300 0.57 -0.180 0.81 0 NA 0.00 15.44

Biotechnology & Drugs ZILA Zila, Inc. NASD Healthcare 195.750 -1.36 30.00 4.28 4.14 NA 45.740 45.300 24.83 1.050 0.95 0 NA 0.09 2.99

Biotechnology & Drugs ZONA Zonagen, Incorporated NASD Healthcare 21.620 NA NA 4.33 3.26 NA 4.990 4.700 17.97 -0.060 5.87 1 NA 0.00 16.00

Biotechnology & Drugs ZMTX ZymeTx, Inc. OTC Healthcare 0.340 NA NA 0.04 NA NA 8.610 6.600 1.46 -0.010 23.31 0 NA NA 0.20

Biotechnology & Drugs ZGEN ZymoGenetics, Inc. NASD Healthcare 1,316.230 NA NA 23.00 5.12 NA 57.230 17.700 28.93 0.920 69.07 -2 NA 0.00 13.35

Major Drugs ABT Abbott Laboratories NYSE Healthcare 72,652.350 1.96 10.42 46.65 5.61 23.30 1,557.390 1,454.200 61.32 8.970 6.63 0 2.23 0.51 1.40

Major Drugs ACL Alcon, Inc. NYSE Healthcare 24,688.020 1.93 16.38 80.60 12.75 30.64 306.300 73.500 21.74 2.060 76.00 0 0.69 0.46 1.28

Major Drugs APNS Applied Neurosolutions, Inc. OTC Healthcare 25.830 NA NA 0.29 16.92 NA 90.640 83.100 6.83 0.000 8.32 0 NA 0.01 10.43





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BioTech Industry 31Dec04





Price to Institutional Total Debt

Market L-Term Current Price to Earnings Current Shares Institutional Net Shrs Insider to Total Current

Ticker Stock Capitalization ($ Mean Grth Price per Book Ratio, Ratio, excl. Outstanding Share Float Percent Held Purchased Ownership Net Insider Dividend Equity, Ratio,

BioTech Industry Symbol Name of Company (issuer) Exchange Economic Sector millions) PEG Ratio Rate (%) Share ($) Quarterly Xord Items (millions) (millions) (%) (%) Percent (%) Trades Yield (%) Quarterly Quarterly

Major Drugs AZN AstraZeneca PLC (ADR) NYSE Healthcare 61,608.270 1.49 11.61 36.39 4.22 17.61 1,693.000 1,676.100 8.81 -0.140 1.00 0 1.62 0.08 2.03

Major Drugs AVE Aventis (ADR) NYSE Healthcare 75,335.300 203.39 0.10 93.90 5.08 24.95 802.290 681.900 0.15 -17.630 15.01 0 1.08 0.37 1.27

Major Drugs BAY Bayer AG (ADR) NYSE Healthcare 24,817.020 2.34 8.05 33.98 1.52 NA 730.340 723.000 3.35 1.970 1.01 0 1.80 0.72 2.01

Major Drugs BMY Bristol-Myers Squibb Co. NYSE Healthcare 49,846.460 -12.78 -1.23 25.62 4.68 18.37 1,945.610 1,928.900 66.90 89.150 0.86 0 4.37 0.96 1.53

Major Drugs LLY Eli Lilly & Co. NYSE Healthcare 64,220.520 1.67 12.09 56.75 5.68 24.12 1,131.640 966.700 68.77 2.470 14.58 -22 2.68 0.55 1.47

Major Drugs GSK GlaxoSmithKline plc (ADR) NYSE Healthcare 135,345.840 2.24 7.48 47.39 12.46 17.85 2,974.730 2,558.250 8.60 30.780 14.00 0 3.08 1.05 1.71

Major Drugs JNJ Johnson & Johnson NYSE Healthcare 188,213.200 1.72 12.01 63.42 5.97 20.81 2,967.730 2,938.000 64.33 34.010 1.00 -6 1.80 0.11 2.18

Major Drugs MRK Merck & Co., Inc. NYSE Healthcare 71,273.170 4.48 2.73 32.14 4.12 11.74 2,217.580 2,195.400 59.52 1.480 1.00 -2 4.73 0.38 1.29

Major Drugs NVD Novadel Pharma Inc AMEX Healthcare 54.590 NA NA 1.63 6.47 NA 33.490 18.400 5.61 0.600 45.06 0 NA 0.00 6.82

Major Drugs NVS Novartis AG (ADR) NYSE Healthcare 122,882.950 1.72 12.25 50.54 3.97 23.95 2,431.400 2,407.100 6.58 18.370 1.00 0 1.55 0.18 2.40

Major Drugs PFE Pfizer Inc. NYSE Healthcare 202,508.470 1.12 11.32 26.89 2.97 22.64 7,531.000 7,456.900 64.76 -72.360 0.98 -1 2.83 0.28 1.55

Major Drugs RHHBY Roche Holding Ltd. (ADR) OTC Healthcare 95,686.920 1.17 16.00 116.35 4.40 24.92 822.410 735.800 0.19 -0.580 10.53 0 NA 0.44 2.61

Major Drugs SHR Schering AG (ADR) NYSE Healthcare 14,107.500 NA NA 74.25 3.67 23.09 190.000 155.800 4.94 2.520 18.00 0 1.60 0.03 2.48

Major Drugs SGP Schering-Plough Corp. NYSE Healthcare 30,751.270 81.38 16.14 20.88 4.52 NA 1,472.760 1,464.400 75.85 48.380 0.57 0 1.05 0.40 2.53

Major Drugs WYE Wyeth NYSE Healthcare 56,823.390 1.79 8.91 42.59 5.11 17.10 1,334.200 1,320.900 75.59 22.430 1.00 -1 2.16 0.73 1.96









492934fc-52f2-4162-9f84-32d5a4e91159.xls BioTech Industry 31Dec04 45 of 45 10/24/2011 3:30 PM