BIOGRAPHICAL SKETCH BIOGRAPHICAL SKETCH by wuyunyi

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									BIOGRAPHICAL SKETCH
NAME                                                                    POSITION TITLE
Slover, Robert H.                                                       Director of Pediatric Services
eRA COMMONS USER NAME (credential, e.g., agency login)                  Wagner Family Chair in Childhood Diabetes
RSLOVER                                                                 Associate Professor of Pediatric Endocrinology
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, include postdoctoral training and
residency training if applicable.)
                                                                        DEGREE
                   INSTITUTION AND LOCATION                                                 MM/YY                   FIELD OF STUDY
                                                                     (if applicable)
Brigham Young University
                                                                           B.S.              6/1971          Pre-Med
Provo, UT
University of Utah Medical School
                                                                          M.D.               6/1975
Salt Lake City, UT                                                                                           Medicine
Fitzsimons Army Medical Center                                                               7/1975-
Aurora, CO                                                                                   6/1976          Intern

Fitzsimons Army Medical Center                                                               7/1976-
                                                                                                             Pediatric Resident
Aurora, CO                                                                                   6/1978

University of Colorado Health Sciences Center                                                7/1980-
                                                                                                             Fellowship
Denver, CO                                                                                   6/1982

A.              Personal Statement
 I have the expertise, leadership, and motivation necessary to successfully carry out the proposed work. I have a
long and broad background in pediatric endocrinology and specifically in Type 1 diabetes with specific expertise and
training in key research areas needed for this study. My specific research work in the past few years has been in
the area of insulin pump and sensor use, including the use of sensor augmented pump as compared to multiple
daily injections (Star 3 Study) in which I was PI. I am currently PI of a study using a ePID closed loop system in
newly-diagnosed patients to rapidly achieve tight control in order to extend islet cell life and C-peptide production
(Artificial Pancreas Consortium/Trial Net). I am also currently PI for a study using a modified closed loop
pump/sensor system to shut off insulin delivery at the point of hypoglycemia during exercise. I have successfully
administered these and other projects ( e.g. staffing, research protection, budget), collaborated with other
researchers, and have participated in or authored several abstracts, posters, and peer-reviewed publications from
these projects. As a result of these previous experiences, I am aware of the importance of frequent communication
among project members and of constructing a realistic research plan, timeline, and budget. In summary, I have
demonstrated a record of successful research in an area of high relevance to this current project.

B.           Positions and Honors
Positions and Employment
1978-1994       United States Army, Pediatric Endocrinologist
1982-1990       Clinical Assistant Professor, University of Colorado, Denver, CO
1982-1994       Chief, General Pediatric Services, Fitzsimons Army Medical Center, Aurora, CO
1984-1994       Clinical Assistant Professor, Bethesda, Maryland
1990-1998       Assistant Professor, University of Colorado, Denver, CO
1998-1999       Associate Professor, University of Colorado, Denver, CO
1999-2002       Mission President, South Korea
2002-2010       Associate Professor, University of Colorado, Denver, CO
2011-Present    Director of Pediatric Services, Barbara Davis Center for Childhood Diabetes, Denver, CO
2011-Present    Wagner Family Chair in Childhood Diabetes, Denver, CO

Other Experience and Professional Memberships
Member, American Diabetes Association
Member, Pediatric Endocrine Society
Member, The Endocrine Society
Member, Western Society of Pediatric Research
Member, International Society for Pediatric and Adolescent Diabetes
Member, American Academy of Pediatrics
Member, Society for Uniformed Endocrinologists
2004-Present      Faculty Senate, University of Colorado Health Sciences Center, Aurora, CO

Honors
Alpha Omega Alpha National Medical Honor Society
Department of Pediatrics Outstanding Teacher
Department of Pediatrics Outstanding Teacher

C.        Selected Peer-reviewed Publications (selected from more than 250 published papers)

1.  Bergenstal R, Tamborlane W, Ahmann A, Buse J, Dailey G, Davis S, Joyce C, Peoples T,
    Perkins B, Welsh J, Willi S, Wood M. Effectiveness of Sensor-Augmented Insulin-Pump
    Therapy in Type 1 Diabetes. The New England Journal of Medicine. 2010 July, 363(4):311-
    320.
 2. Scrimgeour L, Cobry E, McFann K, Burdick P, Weimer C, Slover R, Chase HP. Improved
    Glycemic control after long-term insulin pump use in pediatric patients with type1 diabetes.
    Diabetes Technol Ther. 2007 Oct: 9(5):421-8.
 3. Chase HP, Horner B, McFann K, Yetzer H, Gaston J, Banion C, Fiallo-Scharer R, Slover
    RH, Kligensmith GJ. The Use of Insulin Pumps with Meal Bolus Alarms in Children with
    Type 1 Diabetes to Improve Glycemic Control. Diabetes Care 29:1012-1015, 2006.
4. Barker JM, Goehrig SH, Barriga K, Hoffman M, Slover R, Eisenbarth GS, Norris JM,
    Klingensmith GJ, Rewers M; DAISY study. Clinical characteristics of children diagnosed type
    1 diabetes through intensive screening and follow-up. Diabetes Care. 2004 Jun; 27(6):1399-
    404.
 5. Burdick J, Chase HP, Slover RH, Kneivel K, Scrimgeour L, Maniatis A, Klingensmith GJ.
    Missed Insulin Meal Boluses and Elevated Hemoglobin A1c Levels in Children Receiving
    Insulin Pump Therapy. Pediatrics; 113(3):221-224, 2004.
6. Chase HP, Slover RH, Burdick J, Knievel K, Scrimgeour L, Maniatis AK, Klingensmith GJ.
    Missed Insulin Meal Boluses and Elevated hemoglobin A1c Levels in Children Receiving
    Insulin Pump Therapy. Pediatrics. 2004 Mar; 113(3 Pt 1):e221-4.
7. Redondo MJ, Taylor J, Weiner M, Behnke S, Yu L, Miao D, Haas JE, Slover R, Eisenbarth
    GS, Klingensmith GJ, Hoffenberg EJ, Rewers MJ. Transglutaminase autoantibody screening
    for celiac disease of children with type 1 diabetes. Diabetes Care, 2003.
8. Roberts MD, Slover RH, Chase HP. Diabetic ketoacidosis with intracerebral complications.
    Pediatric Diabetes; 2:109-114, 2001.
9. Maniatis AK, Klingensmith GJ, Slover RH, Mowry CJ, Chase HP. Continuous Subcutaneous
    Insulin Infusion Therapy for Children and Adolescents: An Option for Routine Diabetes Care.
    Pediatrics; 107:2, 351-356, 2001.
10. Rutledge, KS, Chase, HP, Klingensmith, GJ, Walravens, PA, Slover, RH, and Garg, S.K.
    Effectiveness of postprandial humalog in toddlers with diabetes. Pediatrics 100:968-972,
    1997.
11. Slover, RH, Eisenbarth, GS: Prevention of type I diabetes and recurrent beta-cell destruction of
    transplanted islets. Endocrine Reviews 18:241-258, 1997.
12. Sakkal-Alkaddour, H, Zhang, L, Yang, X, Chang, YT, Kappy, M, Slover, RH, Jorgensen, V,
    Pang, S: Studies of 3B-Hydroxysteroid dehydrogenase (3B-HSD) genes in infants and children
    manifesting premature pubarche (PP) and increased ACTH stimulated delta 5 steroid levels.
    Clinical Endocrinology and Metabolism 81:3961-3965, 1996.
13. Slover, RH, Klingensmith, GJ, Gotlin, RW, Radcliffe,J: A comparison of clonidine and
    standard provocative agents of growth hormone. Amer J Dis Child 38:314-317, March 1984.
14. Diabetes & Metabolism [Slover, Robert, H. – Study Group Member]. New Injection
    recommendations for patients with diabetes. El Sevier Masson Vol. 36; 3-18, September 2010.
15. Diabetes & Metabolism [Slover, Robert. H.- Study Group Member]. The Third Injection
    Technique Workshop in Athens (TITAN). El Sevier Masson Vol. 36; 19-29, September 2010.

D.         Research Support

Ongoing Research Support

CEP235/Z25                   Slover (PI)                                              5/1/2010-4/30/2013
X-54, Low glucose suspend feature
The goal of this study is to assess the automatic suspend feature of a partial closed-loop system during exercise in
adults and older adolescents.
Role: PI

ETP08-2448                   Slover (PI)                                               2/22/2010-03/21/2013
MySentry™ remote monitoring system user evaluation
The goal of this study is to assess feasibility of use of a remote alarm for a continuous glucose monitoring system in
a pediatric population.

UOl HD41890:                         Slover (PI)                                     5/1/2009-10/31/2014
Metabolic control at onset of type I diabetes
The goal of this study is to investigate the hypothesis that achievement of extremely tight control through use of a
closed-loop system within the first week of diagnosis in patients with Type 1 diabetes will prolong beta cell life.
(DirectNet).

Completed Research Support

                             Slover (PI)                                   6/1/2007-6/30/2010
Star 3 study
The goal of this study is to compare glucose control over a 12 month period between patients using multiple daily
injections and those using sensor augmented pump therapy.

								
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